Prevention of neurological injuries during mandibular third molar surgery: technical notes

Surgery to the mandibular third molar is common, and injuries to the inferior alveolar nerve and the lingual nerve are well-recognized complications of this procedure. The aim of these technical notes is to describe operative measures for reducing neurological complications during mandibular third molar surgery. The following procedure should be used to prevent damage to the inferior alveolar nerve: a well-designed mucoperiosteal flap, to obtain appropriate access to the surgical area; a conservative ostectomy on the distal and distal-lingual side; tooth sectioning, to facilitate its removal by decreasing the retention zones; tooth dislocation in the path of withdrawal imposed by the curvature of the root apex; and careful socket debridement, when the roots of the extracted tooth are in intimate contact with the mandibular canal. To prevent injury to the lingual nerve, it is important (I) to assess the integrity of the mandibular inner cortex and exclude the presence of fenestration, which could cause the dislocation of the tooth or its fragment into the sublingual or submandibular space; (II) to avoid inappropriate or excessive dislocation proceedings, in order to prevent lingual cortex fracture; (III) to perform horizontal mesial-distal crown sectioning of the lingually inclined tooth; (IV) to protect the lingual flap with a retractor showing the cortical ridge; and (V) to pass the suture not too apically and from the inner side in a buccal-lingual direction in the retromolar are

Nearby early-type galaxies with ionized gas VI. The Spitzer-IRS view

We present low resolution Spitzer-IRS spectra of 40 ETGs, selected from a sample of 65 ETGs showing emission lines in their optical spectra. We homogeneously extract the mid-infrared (MIR) spectra, and after the proper subtraction of a "passive" ETG template, we derive the intensity of the ionic and molecular lines and of the polycyclic aromatic hydrocarbon emission features. We use MIR diagnostic diagrams to investigate the powering mechanisms of the ionized gas. The mid-infrared spectra of early-type galaxies show a variety of spectral characteristics. We empirically sub-divide the sample into five classes of spectra with common characteristics. Class-0, accounting for 20% of the sample, are purely passive ETGs with neither emission lines nor PAH features. Class-1 show emission lines but no PAH features, and account for 17.5% of the sample. Class-2, in which 50% of the ETGs are found, as well as having emission lines, show PAH features with unusual ratios, e.g. 7.7 {\mu}m/11.3 {\mu}m \leq 2.3. Class-3 objects have emission lines and PAH features with ratios typical of star-forming galaxies. 7.5% of objects fall in this class, likely to be objects in a starburst/post-starburst regime. Class-4, containing only 5% of the ETGs, is dominated by a hot dust continuum. The diagnostic diagram [Ne III]15.55{\mu}m/[Ne II]12.8{\mu}m vs. [S III]33.48{\mu}m/[Si II]34.82{\mu}m, is used to investigate the different mechanisms ionizing the gas. If we exclude NGC 3258 where a starburst seems present, most of our ETGs contain gas ionized via either AGN-like or shock phenomena, or both. Most of the spectra in the present sample are classified as LINERs in the optical window. The proposed MIR spectral classes show unambiguously the manifold of the physical processes and ionization mechanisms, from star formation, low level AGN activity, to shocks, present in LINER nuclei.Comment: Accepted for publication in Astronomy and Astrophysic

Nearby early-type galaxies with ionized gas. The UV emission from GALEX observations

We present GALEX far-ultraviolet (FUV, $\lambda_{eff}$=1538 \AA) and near-ultraviolet (NUV, $\lambda_{eff}$=2316 \AA) surface photometry of 40 early-type galaxies (ETGs) selected from a wider sample of 65 nearby ETGs showing emission lines in their optical spectra. We derive FUV and NUV surface brightness profiles, (FUV-NUV) colour profiles and D$_{25}$ integrated magnitudes. We extend the photometric study to the optical {\it r} band from SDSS imaging for 14 of these ETGs. In general, the (FUV-NUV) radial colour profiles become redder with galactocentric distance in both rejuvenated ($\leq 4$ Gyr) and old ETGs. Colour profiles of NGC 1533, NGC 2962, NGC 2974, NGC 3489, and IC 5063 show rings and/or arm-like structures, bluer than the body of the galaxy, suggesting the presence of recent star formation. Although seven of our ETGs show shell systems in their optical image, only NGC 7135 displays shells in the UV bands. We characterize the UV and optical surface brightness profiles, along the major axis, using a Sersic law. The Sersic law exponent, $n$, varies from 1 to 16 in the UV bands. S0 galaxies tend to have lower values of $n$ ($\leq5$). The Sersic law exponent $n=4$ seems to be a watershed: ETGs with $n>4$ tend to have [$\alpha$/Fe] greater than 0.15, implying a short star-formation time scale. We find a significant correlation between the FUV$-$NUV colour and central velocity dispersions $\sigma$, with the UV colours getting bluer at larger $\sigma$. This trend is likely driven by a combined effect of `downsizing' and of the mass-metallicity relation.Comment: Accepted for publication in MNRAS, 33 pages, 7 figure

The star formation history of early-type galaxies as a function of mass and environment

Using the third data release of the Sloan Digital Sky Survey (SDSS), we have rigorously defined a volume-limited sample of early-type galaxies in the redshift range 0.005 < z 64 0.1. We have defined the density of the local environment for each galaxy using a method which takes account of the redshift bias introduced by survey boundaries if traditional methods are used. At luminosities greater than our absolute r-band magnitude cut-off of 1220.45, the mean density of environment shows no trend with redshift. We calculate the Lick indices for the entire sample and correct for aperture effects and velocity dispersion in a model-independent way. We find that early-type galaxies in the field are younger than those in environments typical of clusters but that neither metallicity, \u3b1-enhancement nor carbon enhancement are influenced by the environment. We argue that the timing of the process of formation of early-type galaxies is determined by the environment, while the details of the process of star formation, which has built up the stellar mass, are entirely regulated by the halo mass. These results suggest that the star formation took place after the mass assembly and favours an anti-hierarchical model. In such a model, the majority of the mergers must take place before the bulk of the stars form. This can only happen if there exists an efficient feedback mechanism which inhibits the star formation in low-mass haloes and is progressively reduced as mergers increase the mass

Impact of IFN lambda 3/4 single nucleotide polymorphisms on the cytomegalovirus reactivation in autologous stem cell transplant patients

Cytomegalovirus (CMV) infection represents one of the main cause mortality after Stem Cell Transplantation. Recently, a protective effect of the T allele of rs12979860 IL28B Single Nucleotide Polymorphisms (SNPs) against CMV infection in the allogenic stem cell transplantation was suggested. We investigate whether the rs12979860 IL28B SNP and the relative rs368234815 (IFNλ4) genotype may affect the incidence of active CMV infection in Autologous stem cell transplantation (Auto-SCT) setting. The study included 99 patients who underwent to Auto-SCT. IL28 and IFNΔ4 SNPs were correlated with CMV reactivation along with other clinical and treatment parameters. CMV reactivation by CMV DNAemia was evaluated once a week until day 100 from Auto-SCT. CMV reactivation was documented in 50% (TT-ΔG/ΔG), 35% (CC-TT/TT) and 29.2% (CT-TT/ΔG) of the patients respectively. No differences in CMV copies number were recorded at reactivation between different IL28/IFNλ4 genotypes. The analysis of patients older than 60 years showed a significantly higher incidence of active CMV infection in the TT-ΔG/ΔG (83%) population with respect to CC-TT/TT (21%) and CT-TT/ΔG (40%) patients. Our data suggest a negative role of TT-ΔG/ΔG genotype in the CMV reactivation in Auto-SCT. The exposure to rituximab and the pre-infusion presence of anti CMV IgG also significantly influenced CMV reactivation

Star Formation Histories of the LEGUS Dwarf Galaxies (I): recent History of NGC1705, NGC4449 and Holmberg II

We use HST observations from the Legacy Extragalactic UV Survey to reconstruct the recent star formation histories (SFHs) of three actively star-forming dwarf galaxies, NGC4449, Holmberg II and NGC1705, from their UV color-magnitude diagrams (CMDs). We apply a CMD fitting technique using two independent sets of stellar isochrones, PARSEC-COLIBRI and MIST, to assess the uncertainties related to stellar evolution modelling. Irrespective of the adopted stellar models, all the three dwarfs are found to have had almost constant star formation rates (SFRs) in the last 100-200 Myr, with modest enhancements (a factor of $\sim$2) above the 100 Myr-averaged-SFR. Significant differences among the three dwarfs are found in the overall SFR, the timing of the most recent peak and the SFR$/$area. The Initial Mass Function (IMF) of NGC1705 and Holmberg II is consistent with a Salpeter slope down to $\approx$ 5 M$_{\odot}$, whereas it is slightly flatter, s$=-2.0$, in NGC4449. The SFHs derived with the two different sets of stellar models are consistent with each other, except for some quantitative details, attributable to their input assumptions. They also share the drawback that all synthetic diagrams predict a clear separation in color between upper main sequence and helium burning stars, which is not apparent in the data. Since differential reddening, significant in NGC4449, or unresolved binaries don't appear to be sufficient to fill the gap, we suggest this calls for a revision of both sets of stellar evolutionary tracks.Comment: 22 pages, 17 figures, accepted for publication on Ap

Anthropogenic sinkholes of the city of Naples, Italy: an update

In recent years, the study of anthropogenic sinkholes in densely urbanized areas has attracted the attention of both researchers and land management entities. The city of Naples (Italy) has been frequently affected by processes generating such landforms in the last decades: for this reason, an update of the sinkhole inventory and a preliminary susceptibility estimation are proposed in this work. Starting from previous data, not modified since 2010, a total of 270 new events occurred in the period February 2010–June 2021 were collected through the examination of online newspapers, local daily reports, council chronicle news and field surveys. The final consistence of the updated inventory is of 458 events occurred between 1880 and 2021, distributed through time with an increasing trend in frequency. Spatial analysis of sinkholes indicates a concentration in the central sector of the city, corresponding to its ancient and historic centre, crossed by a dense network of underground tunnels and cavities. Cavity-roof collapse is confirmed as one of the potential genetic types, along with processes related to rainfall events and service lines damage. A clear correlation between monthly rainfall and the number of triggered sinkholes was identified. Finally, a preliminary sinkhole susceptibility assessment, carried out by Frequency Ratio method, confirms the central sector of city as that most susceptible to sinkholes and emphasizes the predisposing role of service lines, mostly in the outermost areas of the city

Ultra Long Period Cepheids: a primary standard candle out to the Hubble flow

The cosmological distance ladder crucially depends on classical Cepheids (with P=3-80 days), which are primary distance indicators up to 33 Mpc. Within this volume, very few SNe Ia have been calibrated through classical Cepheids, with uncertainty related to the non-linearity and the metallicity dependence of their period-luminosity (PL) relation. Although a general consensus on these effects is still not achieved, classical Cepheids remain the most used primary distance indicators. A possible extension of these standard candles to further distances would be important. In this context, a very promising new tool is represented by the ultra-long period (ULP) Cepheids (P \geq 80 days), recently identified in star-forming galaxies. Only a small number of ULP Cepheids have been discovered so far. Here we present and analyse the properties of an updated sample of 37 ULP Cepheids observed in galaxies within a very large metallicity range of 12+log(O/H) from ~7.2 to 9.2 dex. We find that their location in the colour(V-I)-magnitude diagram as well as their Wesenheit (V-I) index-period (WP) relation suggests that they are the counterparts at high luminosity of the shorter-period (P \leq 80 days) classical Cepheids. However, a complete pulsation and evolutionary theoretical scenario is needed to properly interpret the true nature of these objects. We do not confirm the flattening in the studied WP relation suggested by Bird et al. (2009). Using the whole sample, we find that ULP Cepheids lie around a relation similar to that of the LMC, although with a large spread (~0.4 mag).Comment: 8 pages, 4 figures, accepted for publication in Astrophysics & Space Scienc

Mid-infrared colour gradients and the colour-magnitude relation in Virgo early-type galaxies

We make use of Spitzer imaging between 4 and 16 micron and near-infrared data at 2.2 micron to investigate the nature and distribution of the mid-infrared emission in a sample of early-type galaxies in the Virgo cluster. These data allow us to conclude, with some confidence, that the emission at 16 micron in passive ETGs is stellar in origin, consistent with previous work concluding that the excess mid-infrared emission comes from the dusty envelopes around evolved AGB stars. There is little evidence for the mid-infrared emission of an unresolved central component, as might arise in the presence of a dusty torus associated with a low-luminosity AGN. We nonetheless find that the 16 micron emission is more centrally peaked than the near-infrared emission, implying a radial stellar population gradient. By comparing with independent evidence from studies at optical wavelengths, we conclude that a metallicity that falls with increasing radius is the principal driver of the observed gradient. We also plot the mid-infrared colour-magnitude diagram and combine with similar work on the Coma cluster to define the colour-magnitude relation for absolute K-band magnitudes from -26 to -19. Because a correlation between mass and age would produce a relation with a gradient in the opposite sense to that observed, we conclude that the relation reflects the fact that passive ETGs of lower mass also have a lower average metallicity. The colour-magnitude relation is thus driven by metallicity effects. In contrast to what is found in Coma, we do not find any objects with anomalously bright 16 micron emission relative to the colour-magnitude relation. Although there is little overlap in the mass ranges probed in the two clusters, this may suggest that observable ``rejuvenation'' episodes are limited to intermediate mass objects.Comment: 8 pages, 4 figure