Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases

Respiratory tract disease can be associated with primary or secondary bacterial infections in dogs and cats and is a common reason for use and potential misuse, improper use, and overuse of antimicrobials. There is a lack of comprehensive treatment guidelines such as those that are available for human medicine. Accordingly, the International Society for Companion Animal Infectious Diseases convened a Working Group of clinical microbiologists, pharmacologists, and internists to share experiences, examine scientific data, review clinical trials, and develop these guidelines to assist veterinarians in making antimicrobial treatment choices for use in the management of bacterial respiratory diseases in dogs and cats.M.R. Lappin, J. Blondeau, D. Boothe, E.B. Breitschwerdt, L. Guardabassi, D.H. Lloyd, M.G. Papich, S.C. Rankin, J.E. Sykes, J. Turnidge, and J.S. Wees

Young People, Biographical Narratives and the Life Grid: Young People's Accounts of Parental Substance Use

Research into potentially sensitive issues with young people presents numerous methodological and ethical challenges. While recent studies have highlighted the advantages of task-based activities in research with young people, the literature on life history research provides few suggestions as to effective and appropriate research tools for encouraging young people to tell their stories. This paper explores the contribution that may be made to such research by the life grid, a visual tool for mapping important life events against the passage of time and prompting wide-ranging discussion. Critical advantages of the life grid in qualitative research include: its visual element which can help to engage interviewer and interviewee in a process of constructing and reflecting on a concrete life history record; its role in creating a more relaxed research encounter supportive of the respondent’s ‘voice’; and facilitating the discussion of sensitive issues. In addition, the way in which use of the grid anchors such narratives in accounts of everyday life, often revealing interesting tensions, is explored. These points are discussed with reference to an exploratory study of young people’s experience of parental substance use

The E-ELT first light spectrograph HARMONI: capabilities and modes

Trabajo presentado en SPIE Astronomical Telescopes, celebrado en San Diego (California), del 26 de junio al 1 de julio de 2016HARMONI is the E-ELT's first light visible and near-infrared integral field spectrograph. It will provide four different spatial scales, ranging from coarse spaxels of 60 × 30 mas best suited for seeing limited observations, to 4 mas spaxels that Nyquist sample the diffraction limited point spread function of the E-ELT at near-infrared wavelengths. Each spaxel scale may be combined with eleven spectral settings, that provide a range of spectral resolving powers (R 3500, 7500 and 20000) and instantaneous wavelength coverage spanning the 0.5 - 2.4 ¿m wavelength range of the instrument. In autumn 2015, the HARMONI project started the Preliminary Design Phase, following signature of the contract to design, build, test and commission the instrument, signed between the European Southern Observatory and the UK Science and Technology Facilities Council. Crucially, the contract also includes the preliminary design of the HARMONI Laser Tomographic Adaptive Optics system. The instrument's technical specifications were finalized in the period leading up to contract signature. In this paper, we report on the first activity carried out during preliminary design, defining the baseline architecture for the system, and the trade-off studies leading up to the choice of baseline

The Mid-Infrared Instrument for the James Webb Space Telescope, VI: The Medium Resolution Spectrometer

We describe the design and performance of the Medium Resolution Spectrometer (MRS) for the JWST-MIRI instrument. The MRS incorporates four coaxial spectral channels in a compact opto-mechanical layout that generates spectral images over fields of view up to 7.7 × 7.7" in extent and at spectral resolving powers ranging from 1300 to 3700. Each channel includes an all-reflective integral field unit (IFU): an "image slicer" that reformats the input field for presentation to a grating spectrometer. Two 1024 × 1024 focal plane detector arrays record the output spectral images with an instantaneous spectral coverage of approximately one third of the full wavelength range of each channel. The full 5-28.5 mum spectrum is then obtained by making three exposures using gratings and pass-band-determining filters that are selected using just two three-position mechanisms. The expected on-orbit optical performance is presented, based on testing of the MIRI Flight Model and including spectral and spatial coverage and resolution. The point spread function of the reconstructed images is shown to be diffraction limited and the optical transmission is shown to be consistent with the design expectations.published in PASP, vol. 127, issue 953, pp.623-632, 2015status: publishe

Harps-N: the new planet hunter at TNG

The Telescopio Nazionale Galileo (TNG)[9] hosts, starting in April 2012, the visible spectrograph HARPS-N. It is based on the design of its predecessor working at ESO's 3.6m telescope, achieving unprecedented results on radial velocity measurements of extrasolar planetary systems. The spectrograph's ultra-stable environment, in a temperature-controlled vacuum chamber, will allow measurements under 1 m/s which will enable the characterization of rocky, Earth-like planets. Enhancements from the original HARPS include better scrambling using octagonal section fibers with a shorter length, as well as a native tip-tilt system to increase image sharpness, and an integrated pipeline providing a complete set of parameters. Observations in the Kepler field will be the main goal of HARPS-N, and a substantial fraction of TNG observing time will be devoted to this follow-up. The operation process of the observatory has been updated, from scheduling constraints to telescope control system. Here we describe the entire instrument, along with the results from the first technical commissioning

HARMONI: a single-field wide-band integral-field spectrograph for the European ELT

Trabajo presentado en SPIE Astronomical Telescopes, celebrado en San Diego (California), del 15 de junio al 2 de julio de 2010We describe the results of a Phase A study for a single field, wide band, near-infrared integral field spectrograph for the European Extremely Large Telescope (E-ELT). HARMONI, the High Angular Resolution Monolithic Optical & Nearinfrared Integral field spectrograph, provides the E-ELT’s core spectroscopic requirement. It is a work-horse instrument, with four different spatial scales, ranging from seeing to diffraction-limited, and spectral resolving powers of 4000, 10000 & 20000 covering the 0.47 to 2.45 μm wavelength range. It is optimally suited to carry out a wide range of observing programs, focusing on detailed, spatially resolved studies of extended objects to unravel their morphology, kinematics and chemical composition, whilst also enabling ultra-sensitive observations of point sources. We present a synopsis of the key science cases motivating the instrument, the top level specifications, a description of the opto-mechanical concept, operation and calibration plan, and image quality and throughput budgets. Issues of expected performance, complementarity and synergies, as well as simulated observations are presented elsewhere in these proceeding