Investigating single-leg landing strategies and movement control across changes in task demands

Variability is an intrinsic characteristic of human movement, with hypothesized connections to neuromotor functioning and mechanisms of injury. The purpose of this study was to evaluate changes in movement variability among kinematic, kinetic, and electromyographic (EMG) variables following mechanical task demand manipulations during single-leg drop landings. Biomechanical outcome variables included 3 kinematic (sagittal, hip, knee, and ankle angles), 4 kinetic (sagittal hip, knee, ankle moments and vertical ground reaction force; GRFz), and 5 EMG variables (gluteus maximus, vastus medialis, biceps femoris, medial gastrocnemius, and tibialis anterior muscles). Mechanical task demands were altered using load and landing height manipulations, computed as percentages of participant anthropometrics (bodyweight: BW, BW+12.5%, BW+25%, and height: H12.5% and H25%, respectively). Fewer emergent strategies were identified under greater mechanical task demands, defined using the load accommodation strategies model, alongside decreased movement variability, assessed using principal component analysis (PCA). Joint-specific biomechanical adjustments were identified, highlighting mechanisms for the observed load accommodation strategies and changes in movement variability. An increasingly upright landing posture was observed under greater mechanical task demands, decreasing effective landing height and reducing landing impulse. Alterations in movement variability were interpreted in the context of the available functional degrees of freedom at each lower extremity joint, aligning with physiological predictions and theories from motor control. The holistic approach taken in this investigation provided a more complete understanding of mechanisms contributing to changes in movement variability and factors that may underlie landing injuries

Kinematic Effects of Stride Length Perturbations on System COM Horizontal Velocity During Locomotion

PURPOSE: To investigate the kinematic effect on the systems’ center of mass horizontal velocity in response to stride length perturbations. METHODS: Twelve healthy adults (23.1±7.71 yrs; 1.69±0.1 m; 66.82±12.6 kg; leg length 894.7±66.1 mm) performed 5 trials of preferred speed walking (PW) and running (PR)followed by 5 stride length perturbations based on percentages of leg length (60%, 80%, 100%, 120% and 140%). 3D kinematic analysis was completed using a 12-camera infrared motion capture system (Vicon, 200hz). Dependent variables computer for each condition included: center of mass horizontal velocity at the highest vertical position (COMHVhi) and at the lowest vertical position (COMHVlo). Statistical analysis included correlation matrices across levels of perturbation for each dependent variable (α=.05). RESULTS: COMHVhi demonstrated significant correlations with greater than 50% shared variance for PR vs 100% (r=.742), 60% vs 80% (r=.824), 60% vs 100% (r=.748), 60% vs 120% (r=.709), 80% vs 100% (r=.896), 100% vs 120% (r=.887), and 100% vs 140% (r=.728), and 120% vs 140% (r=.895). COMHVlo demonstrated significant correlations with greater than 50% shared variance for PR vs 100% (r=.753), PW vs 80% (r=.794), 60% vs 80% (r=.814), 60% vs 100% (r=.735), 60% vs 120% (r=.748), 80% vs 100% (r=.902), 80% vs 120% (r=.751), 100% vs 120% (r=.892), and 120% vs 140% (r=.710). DISCUSSION: Results suggest PR and PW have a greater relationship to stride length less than or equal to leg length, and thus extending stride length begins to diminish mechanical efficiency. It is a well-established mechanical relationship that horizontal velocity is a product of stride length and stride rate. Study results suggest that increases in stride length beyond 100% of leg length may be less than optimal mechanically. CONCLUSION: Stride lengths greater than 100% leg length during walking may be inefficient, perhaps owing to changes in lower extremity stiffness

Step Length Perturbations Alter Variations in Center of Mass Horizontal Velocity

PURPOSE: The purpose of the study was to investigate the effects of SL perturbations on system COM forward velocity (vx) during walking gait. METHODS: Eight healthy adults (23.5±3.6 yrs; 1.72±0.18 m; 73.11±15.29 kg) performed 5 trials of preferred speed walking (PW) and running (PR) followed by 5 stride length perturbations based on percentages of leg length (LL: 60%, 80%, 100%, 120% and 140%). 3D kinematic analysis was completed using a 12-camera infrared motion capture system (Vicon MX T40-S, 200Hz). Data filtering and interpolation included a low pass, 4th order Butterworth filter (cutoff frequency 15Hz) and cubic (3rd order spline). Maximum and minimum system COMvx comparisons were made independently among stride conditions using one-way repeated measures ANOVA and Bonferroni post-hoc contrasts. Change in system COMvx across gait stride were evaluated using one-way repeated measures ANOVA and Bonferroni post-hoc contrasts (α=0.05). RESULTS: Differences in maximum COMvx were detected among stride conditions (F[1.847,59.105]=339.458, pdetected among stride conditions (F[2.118,65.666] =130.951, pdetected significantly greater ΔCOMvx at 140% LL, and significantly less ΔCOMvx at 60% LL (p≤.005). DISCUSSION: Differences in maximum COMvx were detected among stride conditions (F[1.847,59.105]=339.458,

Biomechanics and neural control of movement, 20 years later: what have we learned and what has changed?

We summarize content from the opening thematic session of the 20th anniversary meeting for Biomechanics and Neural Control of Movement (BANCOM). Scientific discoveries from the past 20 years of research are covered, highlighting the impacts of rapid technological, computational, and financial growth on motor control research. We discuss spinal-level communication mechanisms, relationships between muscle structure and function, and direct cortical movement representations that can be decoded in the control of neuroprostheses. In addition to summarizing the rich scientific ideas shared during the session, we reflect on research infrastructure and capacity that contributed to progress in the field, and outline unresolved issues and remaining open questions

Syndromic surveillance using minimum transfer of identifiable data: the example of the National Bioterrorism Syndromic Surveillance Demonstration Program

Several health plants and other organizations are collaborating with the Centers for Disease Control and Prevention to develop a syndromic surveillance system with national coverage that includes more than 20 million people. A principal design feature of this system is reliance on daily reporting of counts of individuals with syndromes of interest in specified geographic regions rather than reporting of individual encounter-level information. On request from public health agencies, health plans and telephone triage services provide additional information regarding individuals who are part of apparent clusters of illness. This reporting framework has several advantages, including less sharing of protected health information, less risk that confidential information will be distributed inappropriately, the prospect of better public acceptance, greater acceptance by health plans, and less effort and cost for both health plans and public health agencies. If successful, this system will allow any organization with appropriate data to contribute vital information to public health syndromic surveillance systems while preserving individuals’ privacy to the greatest extent possible

Hip Fracture Incidence in Relation to Age, Menopausal Status, and Age at Menopause: Prospective Analysis

Using data from the UK Million Women Study, Emily Banks and colleagues investigate the relationships between the incidence of hip fracture and a woman's age, menopausal status, and age at menopause

SN Zwicky: uncovering a population of gravitational lens galaxies with magnified "standard candles"

We report the discovery of a very rare phenomenon, a multiply-imaged gravitationally lensed Type Ia supernova (SNe Ia), "SN Zwicky", a.k.a. SN 2022qmx, magnified nearly twenty-five times by a foreground galaxy. The system was identified as intrinsically bright thanks to the "standard candle" nature of SNe Ia. Observations with high-spatial resolution instruments resolved a system with four nearly simultaneous images, with an Einstein radius of only $\theta_E =0.167"$, corresponding to a lens mass of $8\cdot 10^9$ solar masses within a physical size below $0.8$ kiloparsecs. A smooth lens model fails to reproduce the image flux ratios, suggesting significant additional magnification from compact objects. Given the small image splitting and a relatively faint deflecting galaxy, the lensing system would not have been found through the angular separation technique generally used in large imaging surveys

Long working hours and risk of coronary heart disease and stroke : a systematic review and meta-analysis of published and unpublished data for 603 838 individuals

Background Long working hours might increase the risk of cardiovascular disease, but prospective evidence is scarce, imprecise, and mostly limited to coronary heart disease. We aimed to assess long working hours as a risk factor for incident coronary heart disease and stroke. Methods We identified published studies through a systematic review of PubMed and Embase from inception to Aug 20, 2014. We obtained unpublished data for 20 cohort studies from the Individual-Participant-Data Meta-analysis in Working Populations (IPD-Work) Consortium and open-access data archives. We used cumulative random-effects meta-analysis to combine effect estimates from published and unpublished data. Findings We included 25 studies from 24 cohorts in Europe, the USA, and Australia. The meta-analysis of coronary heart disease comprised data for 603 838 men and women who were free from coronary heart disease at baseline; the meta-analysis of stroke comprised data for 528 908 men and women who were free from stroke at baseline. Follow-up for coronary heart disease was 5.1 million person-years (mean 8.5 years), in which 4768 events were recorded, and for stroke was 3.8 million person-years (mean 7.2 years), in which 1722 events were recorded. In cumulative meta-analysis adjusted for age, sex, and socioeconomic status, compared with standard hours (35-40 h per week), working long hours (>= 55 h per week) was associated with an increase in risk of incident coronary heart disease (relative risk [RR] 1.13, 95% CI 1.02-1.26; p=0.02) and incident stroke (1.33, 1.11-1.61; p=0.002). The excess risk of stroke remained unchanged in analyses that addressed reverse causation, multivariable adjustments for other risk factors, and different methods of stroke ascertainment (range of RR estimates 1.30-1.42). We recorded a dose-response association for stroke, with RR estimates of 1.10 (95% CI 0.94-1.28; p=0.24) for 41-48 working hours, 1.27 (1.03-1.56; p=0.03) for 49-54 working hours, and 1.33 (1.11-1.61; p=0.002) for 55 working hours or more per week compared with standard working hours (p(trend) Interpretation Employees who work long hours have a higher risk of stroke than those working standard hours; the association with coronary heart disease is weaker. These findings suggest that more attention should be paid to the management of vascular risk factors in individuals who work long hours. Copyright (C) Kivimaki et al. Open Access article distributed under the terms of CC BY.Peer reviewe