Educar para la paz desde la etapa de Infantil a través de la coeducación

Treball Final de Grau en Mestre o Mestra d'Educació Infantil. Codi: MI1040. Curs acadèmic: 2016/2017Este trabajo final de grado (TFG) de carácter experimental tiene como principal objetivo promover la coeducación y la deconstrucción de los roles de género en las aulas de Infantil. Ha sido implementado en el CEIP Blasco Ibáñez de Castellón de la Plana. Considero de suma importancia que los niños y niñas desde pequeños sean conscientes de los estereotipos por cuestiones de género que impregnan nuestra sociedad y cómo se heredan sutilmente de generación a generación sin apenas darnos cuenta. La idea de la propuesta coeducativa es educar en la igualdad a través de la eliminación de los roles de género que se reproducen en el sistema educativo como subsistema social. Esta reproducción de roles de género conlleva a la cultura de la violencia, puesto que, en gran medida, sitúa al rol del género femenino en desventaja, en inferioridad con respecto al masculino. Por todo ello, se propone la coeducación como elemento clave para la educación para la paz.This final degree (GFR) of experimental work aims promote coeducation and the deconstruction of gender in the classrooms of child roles. It has been implemented in the CEIP Blasco Ibáñez de Castellón de la Plana. I consider of the utmost importance that young children are aware of stereotypes by gender issues that pervade our society and how they are inherited subtly from generation to generation without even realizing. The idea of coeducational proposal is educating the equality through the Elimination of gender roles that breed in the educational system as a social subsystem. This reproduction of gender roles leads to the culture of violence, since, largely, it is located at the role of women at a disadvantage, inferiority with respect to the male. Therefore intends to coeducation as a key element for education for peace

The Sounds of Japanese Noise: First Generation of Japanese Noise-Artists

This article presents pan of my research on a type of electronic music known as Japanese noise carried out for my Honors Thesis in Music, Creating Silence through Noise: an Aesthetic Approach to the Sounds of Japanese noise . It introduces Japanese noise, its origins in the 1970s and 1980s, its musical influences, and the early distribution of its pieces. The first generation of Japanese noise artists and their perceptions of Tokyo are then discussed. Finally, the possibility is advanced of a correlation between such perceptions of the city and the sounds of Japanese noise

Exploring and developing the self-determination of Mexican young adults with intellectual disability following a dialogic approach

The aim of this study was to explore the understandings and experiences of self-determination of a group of Mexican young adults with intellectual disability, in particular, how self-determination could be promoted or hindered in dialogue. In this research self-determination is understood in terms of a person’s conscious and intentional decision-making in interaction with a supportive context of opportunities and encouragement. Self-determination theories emphasise interaction and relationality. Moreover, educational programmes to promote self-determination of young adults with intellectual disability commonly rely on interaction between students and educators to set goals and make plans to achieve them. Yet published studies tend to follow individualistic approaches and employ methods that fail to attend to the interaction and relationality of self-determination, and to the young people’s voices and perspectives. The current project aims to contribute to the field of self-determination, internationally and specifically in Latin America where studies on the self-determination of young adults with intellectual disability are scarce. This project also aims to contribute to the field of dialogic theory which has highlighted the need to widen and deepen the understanding of dialogic education through the inclusion of diverse perspectives, and yet has until now left aside the voices and perspectives of people with intellectual disability. This research involved 10 Mexican young adults with intellectual disability who are students at the university-based transition programme: Building Bridges. I facilitated group discussions with these students and three teachers around topics that were of the students’ interest. I also observed naturally occurring interactions of these students with other people in university, work and independent-living contexts. Fieldnotes and verbatim transcriptions were generated. Thematic analysis of the data generated led to the development of six themes that interplay in the students’ decision-making process: decisions, aspirations, preparation, challenges, self-advocacy and supports. Sociocultural discourse analysis of conversations about the students’ ‘Challenge of the Month’ goals showed how the students’ agency (i.e., intentional decision-making) is negotiated in the interaction and how students’ volition (i.e., conscious decision-making) could be promoted through dialogic interactions. Potential constraints on students’ agency and volition development are evident when discussions of concrete courses of action are prioritised over discussions that would lead students to reflect more deeply on the motives behind their goals, and when educators fail to delve into the students' aspirations and decisions and instead propose other 'more viable' options straightaway. This dissertation upholds the importance of studying self-determination as a contextual and relational phenomenon which could be promoted or hindered in dialogue. The findings may encourage educators and researchers to create opportunities for engagement in dialogic interactions with young adults with intellectual disability in order to collaboratively reflect on important life decisions and aspirations and thus promote self-determination.National Council on Science and Technology of Mexico (CONACYT) Fellow CVU No 764025 Cambridge Commonwealth European and International Trus

Efecto del programa "Modelipinto" en la motricidad fina de los niños de 4 años. Virú, 2023

En la presente investigación, se consideró como objetivo general determinar el efecto del programa Modelipinto en la motricidad fina de los niños de 4 Años del Colegio María de Fátima Virú; desarrollándose una investigación de tipo aplicada, pre experimental con pre y post test, en una muestra de 20 niños; donde se optó por emplear para la recolección de datos , la técnica de la observación y como instrumento una guía de observación; que al ser sometida a la prueba de Alpha de Cronbach obtuvo una fiabilidad de 0,861.Entre los principales resultados se halló que en el pre test el nivel de motricidad 60%, estuvo bajo y el 65% de niños; medio asimismo, se estableció que el programa ejerce un efecto significativo en la coordinación bimanual, viso manual y grafo perceptiva en los niños; se obtuvo además un valor p=0.000 y Z = -4,793 según la prueba de Wilcoxon por lo que se concluyó que el programa Modelipinto prevalece el nivel en proceso,seguiendo el nivel logrado en niños de 4 años del Colegio María de Fátima Virú

Ácidos biliares y transaminasas séricas como predictores de complicaciones fetales en gestantes con colestasis intrahepática. Hospital Nacional Alberto Sabogal Sologuren. Callao. 2015 - 2016

Objetivo: Determinar si los ácidos biliares y transaminasas séricas son predictores de complicaciones fetales en gestantes con Colestasis Intrahepática en el Hospital Nacional Alberto Sabogal Sologuren. Material y métodos: Estudio de pruebas diagnósticas, retrospectivo, observacional, en 73 gestantes con colestasis intrahepatica estableciéndose dos grupos de estudio de 43 y 30 gestantes de acuerdo a la presencia o ausencia de complicaciones fetales. Se calculó la sensibilidad, especificidad, valor predictivo positivo y negativo. Se aplicó el test de chi cuadrado y área bajo la curva. Resultados: Los puntos de corte encontrados fueron los siguientes; ácidos biliares séricos: 35.5 umol/L, Alanina aminotransferasa: 56.5 U/L y para Aspartato aminotransferasa 76.5 U/L. La sensibilidad, especificidad, VPP y VPN de los ácidos biliares fueron 76,74%; 90.0%; 91.67%; 91.67% y 72.97% respectivamente. Con respecto a las transaminasas; para la Alanina aminotransferasa se encontró: sensibilidad 55.81%, especificidad: 63.33; VPP: 68.57%; VPN: 50 y en el caso del Aspartato aminotransferasa se obtuvo: sensibilidad: 62.79%, especificidad: 70%, VPP: 75% y VPN: 56.8% y el área bajo la curva para los ácidos biliares de 0.887 Conclusiones: Los ácidos biliares y transaminasas séricas son predictores de complicaciones fetales en gestantes con Colestasis Intrahepática.Objective: To determine if bile acids and serum transaminases are predictors of fetal complications in pregnant women with Intrahepatic Cholestasis at the Alberto Sabogal Sologuren National Hospital. Material and methods: A retrospective, observational study of diagnostic tests in 73 pregnant women with intrahepatic cholestasis, establishing two study groups of 43 and 30 pregnant women according to the presence or absence of fetal complications. Sensitivity, specificity, positive and negative predictive value were calculated. The chi square test and area under the curve were applied. Results: The cut-off points found were as follows; Serum bile acids: 35.5 umol / L, Alanine aminotransferase: 56.5 U / L and for Aspartate aminotransferase 76.5 U / L. The sensitivity, specificity, VPP and NPV of bile acids were 76.74%; 90.0%; 91.67%; 91.67% and 72.97% respectively. With regard to transaminases; For the Alanine aminotransferase was found: sensitivity 55.81%, specificity: 63.33; VPP: 68.57%; VPN: 50 and in the case of Aspartate aminotransferase: sensitivity: 62.79%, specificity: 70%, PPV: 75% and NPV: 56.8% and the area under the curve for bile acids of 0.887 Conclusions: Bile acids and serum transaminases are predictors of fetal complications in pregnant women with Intrahepatic Cholestasis.Tesi

Dificultades Financieras y Alternativas de Solución que utiliza la Empresa Comercial Distribuidora Rizo Jarquín Del Municipio de Matagalpa, en el I semestre del año 2014

En el presente trabajo investigativo se estudió la Gestión en el Área Financiera de las empresas de Matagalpa, para analizar las Dificultades Financieras y Alternativas de Solución que utiliza la Empresa Comercial Distribuidora Rizo Jarquín del municipio de Matagalpa en el I semestre del año 2014. La importancia de esta temática es que ayuda a administrar mejor los recursos financieros y aumentar el valor de la organización, también brinda un material de apoyo al momento de realizar el presupuesto, el cual admite implementar la proyección de metas para determinado periodo, además sirve de ayuda para que los funcionarios de la empresa estén preparados para enfrentar las diferentes dificultades que se presenten en la entidad. La gestión financiera requiere de mayor organización demandando más funcionarios en el área como especialistas, eso dependiendo del tamaño de la empresa. Las principales conclusiones de este estudio fueron que la Distribuidora Rizo Jarquín presenta como dificultad financiera un bajo nivel de ventas en algunos meses del año, para el cual hacen uso de la alternativa de implementar promociones en los productos sin afectar su valor agregado para así poder superar esta debilidad, haciendo uso de las etapas de los problemas financieros al igual que las fuentes de información para identificar los problemas; aplicándolas de manera general y empíric

Microenvironmental FGF2 regulates glioblastoma stem cells through FGFR1- ERK1/2-ZEB1 axis

Glioblastoma (GBM) is the most lethal and aggressive brain cancer in adults with a median survival of approximately 20 months after diagnosis. GBM represents a highly infiltrative and heterogenous tumour, formed by populations of cells harbouring diverse molecular signatures and responses to therapy. Tumour recurrence and poor prognosis have been thought to be a consequence of resident glioblastoma stem cells (GSCs), which are quiescent cells capable of self-renewal, migration and initiation of new tumours. These cells are subject to cell-autonomous factors and extrinsic cues, which are translated into cell responses that promote tumour progression. Particularly, trophic factors from the tumour microenvironment, such as fibroblast growth factor 2 (FGF2), are essential to GBM growth and GSC maintenance. FGF2 and its cognate receptors have been linked to malignancy and progression in GBM as they promote angiogenesis, proliferation and GSC self-renewal. However, the specific mechanisms of how this growth factor contributes to GSC functions remain incompletely understood. Therefore, we analysed expression of FGF receptors (FGFRs) and the effects of FGF2 on patient-derived glioblastoma cells. We found that FGF2 induces expression of the stemness-associated transcription factors ZEB1, SOX2 and OLIG2. Analysis of FGFR1-3 function using knockdown approaches in patient-derived glioblastoma cell lines revealed that FGFR1 was the only FGFR relevant for GSC maintenance. FGFR1 knockdown reduced sphere/colony-formation, invasion and increased survival in xenograft mouse models. On the other hand, serial dilution orthotopic xenografts of FGFR1+ sorted cells revealed higher tumour formation capacity than FGFR1- cells, consistent with a stem cell population. We found that differentiated cancer cells showed a reduction in FGFR1, ZEB1, SOX2 and OLIG2 expression, and that FGFR1 regulated ZEB1 function through ERK1/2 signalling. Finally, analysis of large-scale gene-expression datasets revealed association of FGFR1 with the mesenchymal subclass of glioblastoma and increased expression levels of FGFR1 in 30-40% of cases. Therefore, in this thesis we demonstrate that FGF2-FGFR1 axis regulates key stemness transcription factors and identify FGFR1 as a potential GSC marker and therapeutic target