2,885 research outputs found
High angular resolution near-IR view of the Orion Bar revealed by Keck/NIRC2
Nearby Photo-Dissociation Regions (PDRs), where the gas and dust are heated
by the far UV-irradiation emitted from stars, are ideal templates to study the
main stellar feedback processes. With this study we aim to probe the detailed
structures at the interfaces between ionized, atomic, and molecular gas in the
Orion Bar. This nearby prototypical strongly irradiated PDR will be among the
first targets of the James Webb Space Telescope (JWST) within the framework of
the PDRs4All Early Release Science program. We employed the sub-arcsec
resolution accessible with Keck-II NIRC2 and its adaptive optics system to
obtain the most detailed and complete images, ever performed, of the
vibrationally excited line H 1-0 S(1) at 2.12~m, tracing the
dissociation front, and the [FeII] and Br lines, at 1.64 and
2.16~m respectively, tracing the ionization front. We obtained narrow-band
filter images in these key gas line diagnostic over at spatial
scales of 0.1 (0.0002~pc or 40~AU at 414~pc). The
Keck/NIRC2 observations spatially resolve a plethora of irradiated
sub-structures such as ridges, filaments, globules and proplyds. A remarkable
spatial coincidence between the H 1-0 S(1) vibrational and HCO J=4-3
rotational emission previously obtained with ALMA is observed. This likely
indicates the intimate link between these two molecular species and highlights
that in high pressure PDR the H/H and C/C/CO transitions zones come
closer as compared to a typical layered structure of a constant density PDR.
This is in agreement with several previous studies that claimed that the Orion
Bar edge is composed of very small, dense, highly irradiated PDRs at high
thermal pressure immersed in a more diffuse environment
Physical Activity Levels in U.S. Latino/Hispanic Adults
Physical activity (PA) prevalence among U.S. Latino/Hispanic adults of diverse backgrounds is not well known. This study describes PA among a representative sample of U.S. Latino/Hispanic adults
Analysis of Neptune's 2017 Bright Equatorial Storm
We report the discovery of a large (8500 km diameter) infrared-bright
storm at Neptune's equator in June 2017. We tracked the storm over a period of
7 months with high-cadence infrared snapshot imaging, carried out on 14 nights
at the 10 meter Keck II telescope and 17 nights at the Shane 120 inch reflector
at Lick Observatory. The cloud feature was larger and more persistent than any
equatorial clouds seen before on Neptune, remaining intermittently active from
at least 10 June to 31 December 2017. Our Keck and Lick observations were
augmented by very high-cadence images from the amateur community, which
permitted the determination of accurate drift rates for the cloud feature. Its
zonal drift speed was variable from 10 June to at least 25 July, but remained a
constant m s from 30 September until at least 15
November. The pressure of the cloud top was determined from radiative transfer
calculations to be 0.3-0.6 bar; this value remained constant over the course of
the observations. Multiple cloud break-up events, in which a bright cloud band
wrapped around Neptune's equator, were observed over the course of our
observations. No "dark spot" vortices were seen near the equator in HST imaging
on 6 and 7 October. The size and pressure of the storm are consistent with
moist convection or a planetary-scale wave as the energy source of convective
upwelling, but more modeling is required to determine the driver of this
equatorial disturbance as well as the triggers for and dynamics of the observed
cloud break-up events.Comment: 42 pages, 14 figures, 6 tables; Accepted to Icaru
The impact of snow cover on nutrients dynamics in Western Siberia territories
International audienc
Impact of Controlling the Site Distribution of Al Atoms on Catalytic Properties in Ferrierite-Type Zeolites
Zeolites with the ferrierite (FER) topology are synthesized using a combination of tetramethylammonium
(TMA) cations with differently sized cyclic amines (pyrrolidine (Pyr), hexamethyleneimine (HMI), and 1,4-
diazabicyclo[2.2.2]octane (DAB)). Using these organic structure-directing agents (SDAs), low Si/Al ratios
and concentrated synthesis mixtures favor the crystallization of FER materials. Increasing the size of the
cyclic amine or decreasing the aluminum content leads to the crystallization of other phases or the creation
of excessive amounts of connectivity defects. TMA cations play a decisive role in the synthesis of the FER
materials, and their presence allows the use of HMI to synthesize FER. Proton MAS NMR is used to quantify
the accessibility of pyridine to acid sites in these FER samples, where it is found that the FER + HMI + TMA
sample contains only 27% acid sites in the 8-MR channels, whereas FER + Pyr and FER + Pyr + TMA
contain 89% and 84%, respectively. The constraint index (CI) test and the carbonylation of dimethyl ether
(DME) with carbon monoxide are used as probe reactions to evaluate how changes in the aluminum distribution
in these FER samples affect their catalytic behavior. Results show that the use of Pyr as an SDA results in
the selective population of acid sites in the 8-MR channels, whereas the use of HMI generates FER zeolites
with an increased concentration of acid sites in the 10-MR channels
Pharmacologic and Clinical Considerations of Nalmefene, a Long Duration Opioid Antagonist, in Opioid Overdose
Opioid use disorder is a well-established and growing problem in the United States. It is responsible for both psychosocial and physical damage to the affected individuals with a significant mortality rate. Given both the medical and non-medical consequences of this epidemic, it is important to understand the current treatments and approaches to opioid use disorder and acute opioid overdose. Naloxone is a competitive mu-opioid receptor antagonist that is used for the reversal of opioid intoxication. When given intravenously, naloxone has an onset of action of approximately 2 min with a duration of action of 60–90 min. Related to its empirical dosing and short duration of action, frequent monitoring of the patient is required so that the effects of opioid toxicity, namely respiratory depression, do not return to wreak havoc. Nalmefene is a pure opioid antagonist structurally similar to naltrexone that can serve as an alternative antidote for reversing respiratory depression associated with acute opioid overdose. Nalmefene is also known as 6-methylene naltrexone. Its main features of interest are its prolonged duration of action that surpasses most opioids and its ability to serve as an antidote for acute opioid overdose. This can be pivotal in reducing healthcare costs, increasing patient satisfaction, and redistributing the time that healthcare staff spend monitoring opioid overdose patients given naloxone
Response to comment on 'Amphibian fungal panzootic causes catastrophic and ongoing loss of biodiversity'
Lambert et al. question our retrospective and holistic epidemiological assessment of the role of chytridiomycosis in amphibian declines. Their alternative assessment is narrow and provides an incomplete evaluation of evidence. Adopting this approach limits understanding of infectious disease impacts and hampers conservation efforts. We reaffirm that our study provides unambiguous evidence that chytridiomycosis has affected at least 501 amphibian species
Modulation of SF1 neuron activity coordinately regulates both feeding behaviour and associated emotional states
Feeding requires the integration of homeostatic drives with emotional states relevant to food procurement in potentially hostile environments. The ventromedial hypothalamus (VMH) regulates feeding and anxiety, but how these are controlled in a concerted manner remains unclear. Using pharmacogenetic, optogenetic, and calcium imaging approaches with a battery of behavioral assays, we demonstrate that VMH steroidogenic factor 1 (SF1) neurons constitute a nutritionally sensitive switch, modulating the competing motivations of feeding and avoidance of potentially dangerous environments. Acute alteration of SF1 neuronal activity alters food intake via changes in appetite and feeding-related behaviors, including locomotion, exploration, anxiety, and valence. In turn, intrinsic SF1 neuron activity is low during feeding and increases with both feeding termination and stress. Our findings identify SF1 neurons as a key part of the neurocircuitry that controls both feeding and related affective states, giving potential insights into the relationship between disordered eating and stress-associated psychological disorders in humans
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