"Más allá del arco iris" : trayectorias de carrera de parejas homosexuales

Este trabalho buscou compreender como se constrói a carreira de casais homossexuais, individual e conjuntamente, e como são negociadas as trajetórias frente às possibilidades existentes. Realizou-se uma pesquisa qualitativa com seis casais de diferentes idades, formações profissionais e tempo de relação. A coleta de dados ocorreu em dois momentos: entrevistas individuais e com o casal. Para análise dos relatos seguiu-se a análise de conteúdo. Os resultados apontaram que a construção do projeto coletivo evidencia a metamorfose dos projetos individuais e redirecionamentos de carreira com alternância na valorização das trajetórias individuais, permitindo explorar nuances e pontos de virada nas trajetórias de casais de dupla carreira. Se por um lado há maior liberdade para negociações das carreiras, por outro, no campo de possibilidades da trajetória de cada um, emerge um espaço de dilemas e conflitos, na forma como estes casais vivenciam papeis e status em uma sociedade pautada na heteronormatividade.This paper aimed to understand how homosexual couples build their careers, individually and jointly, and how trajectories are negotiated considering existing possibilities. Qualitative research was carried out with six homosexual couples of various ages, professional backgrounds, and relationship stages. The data collection had two moments: individual interviews and a joint interview. Analysis of the reports was based on content analysis. The results indicated that the construction of the collective project clearly shows the metamorphosis of the individual projects and career redirections with greater alternation in the valuation of the individual trajectories. This allows the exploration of nuances and turning points of the trajectories of dual career couples. While on the one hand there is greater freedom for negotiations regarding careers, on the other hand, in the field of possibilities for each trajectory, a space of dilemmas and conflicts emerges, in the way these couples experience roles and status in a society based on heteronormativity.Este trabajo buscó comprender cómo se construye la carrera de parejas homosexuales, individual y conjuntamente, y cómo se negocian las trayectorias frente a las posibilidades existentes. Se realizó una investigación cualitativa con seis parejas de diferentes edades, formaciones profesionales y tiempo de relación. La recolección de datos tuvo dos momentos: entrevista individual y entrevista con la pareja. Para la investigación de los datos se siguió el análisis de contenido. Los resultados apuntaron que la construcción del proyecto colectivo evidencia la metamorfosis de los proyectos individuales y redirecciones de carrera con mayor alternancia en la valorización de las trayectorias, permitiendo explorar matices y puntos de giro de trayectorias de parejas de doble carrera. Si, por un lado, hay mayor libertad para negociaciones de las carreras, por otro, en el campo de posibilidades de la trayectoria de cada uno, emerge un espacio de dilemas y conflictos, en la forma en que estas parejas vivencian papeles y status en una sociedad pautada en la heteronormatividad

EXCESSIVE DAYTIME SLEEPNESSAND CARDIOMETABOLIC RISK FACTORS IN CHILDREN AND TEENAGERS WITH OVERWEIGHT

Introdução: atualmente, é observada tendência exacerbada para sonolência diurna excessivaem crianças e adolescentes com excesso de peso. A obesidade e os distúrbios do sono, têmefeito conjunto nas doenças cardiovasculares e no diabetes mellitus. Objetivo: avaliar aprevalência de sonolência diurna excessiva e sua associação com fatores de riscocardiometabólicos. Método: estudo de corte transversal realizado em serviço público, referênciaem atendimento a crianças e adolescentes com excesso de peso no período de junho de 2011a março de 2013, em Campina Grande/PB. A amostra foi composta por 140 crianças e adolescentesde cinco a 18 anos. Foi realizada antropometria, aferida a pressão arterial, aplicado questionáriosobre hábitos do sono, Escala de Sonolência de Epworth e realizados exames laboratoriais(perfil lipídico, glicemia, insulina, HOMA-RI, hemoglobia glicada, proteína C-reativa ultrassensívele leptina). Os dados foram analisados pelo SPSS (v.17), através dos testes do Qui-quadrado, devariância e da correlação de Pearson, com nível de significância de 5%. Resultados: A prevalênciade sonolência diurna excessiva foi de 19,3% e foi maior nas meninas. naqueles com SDE foiobservado maior percentual de alteração nos níveis de LDL, HbA1c e PCR-u, porém sem significânciaestatística. Conclusões: a presença de sonolência na amostra estudada foi prevalente e a aquelescom esta condição apresentaram resultados metabólicos menos favoráveis.Introduction: Currently, an exacerbated trend for excessive daytime sleepiness in overweightchildren and adolescents has been observed. Obesity and sleep disorders have a combinedeffect on cardiovascular diseases and diabetes mellitus. The aim of the study was to evaluatethe prevalence of excessive daytime sleepiness and its association with cardiometabolic riskfactors. Method: Cross-sectional study carried out in a public service, which is reference servicefor overweight children and adolescents in the period from June 2011 to March 2013 in CampinaGrande / PB. The sample consisted of 140 children and adolescents aged from five to 18 years.Anthropometry and blood pressure measures were performed and a questionnaire on sleephabits and Epworth Sleepiness Scale were applied. Laboratory tests were also conducted (lipidprofile, blood glucose levels, insulin, HOMA-IR, glycated hemoglobin, ultrasensitive C-reactiveprotein and leptin). Data were analyzed using SPSS software (v.17), through the chi-squaretest, ANOVA and Pearson’s correlation, with significance level of 5%. Results: the prevalence ofexcessive daytime sleepiness was 19.3% and it was higher among girls. In those with excessivedaytime sleepiness was observed the highest percentage change in LDL levels, HbA1c and CRPu,but without statistical significance. Conclusions: the presence of sleepiness were prevalentin this sample, and those with this condition showed less favorable metabolic results

A meliponicultura como atividade produtiva: Uma análise em comunidade quilombola do Sertão paraibano

Nas comunidades quilombolas, o mel, o cerume e o pólen, produzidos pelas abelhas nativas são bastante utilizados possuindo fins diversos, que variam de acordo com a cultura local. O presente estudo teve como objetivo mostrar que a meliponicultura pode constituir-se numa oportunidade de renda complementar para os quilombolas do município de Diamante no Estado da Paraíba. A coleta dos dados foi realizada no período de setembro a outubro de 2015, oportunidade em que se utilizou um questionário previamente elaborado, contendo questões subjetivas. Constatou-se que em relação à assistência técnica por parte dos órgãos públicos e do incentivo para a prática da meliponicultura, a maioria dos participantes nunca receberam a visita de um técnico para tratar do assunto e que apenas uma pequena parcela participou de alguma capacitação técnicas. Por outro lado, 85% dos participantes acreditam que o principal obstáculo enfrentado por eles em relação à meliponicultura diz respeito à falta de apoio e de assistência técnica; 15% acrescentaram que além desses obstáculos, a falta de uma flora apropriada na região também tem contribuído para limitar a produção de mel na comunidade

Intestinal microsporidiosis: a hidden risk in rheumatic disease patients undergoing anti-tumor necrosis factor therapy combined with disease-modifying anti-rheumatic drugs?

OBJECTIVE: Immunosuppressed patients are at risk of microsporidiosis, and this parasitosis has an increased rate of dissemination in this population. Our objective was to evaluate the presence of microsporidiosis and other intestinal parasites in rheumatic disease patients undergoing anti-tumor necrosis factor/disease-modifying anti-rheumatic drug treatment. METHODS: Ninety-eight patients (47 with rheumatoid arthritis, 31 with ankylosing spondylitis and 11 with psoriatic arthritis) and 92 healthy control patients were enrolled in the study. Three stool samples and cultures were collected from each subject. RESULTS: The frequency of microsporidia was significantly higher in rheumatic disease patients than in control subjects (36 vs. 4%, respectively; p<0.0001), as well as in those with rheumatic diseases (32 vs. 4%, respectively; p<0.0001), ankylosing spondylitis (45 vs. 4%, respectively; p<0.0001) and psoriatic arthritis (40 vs. 4%, respectively; p<0.0001), despite a similar social-economic class distribution in both the patient and control groups (p = 0.1153). Of note, concomitant fecal leukocytes were observed in the majority of the microsporidia-positive patients (79.5%). Approximately 80% of the patients had gastrointestinal symptoms, such as diarrhea (26%), abdominal pain (31%) and weight loss (5%), although the frequencies of these symptoms were comparable in patients with and without this infection (p&gt;0.05). Rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis disease activity parameters were comparable in both groups (p&gt;0.05). The duration of anti-tumor necrosis factor/disease-modifying anti-rheumatic drugs and glucocorticoid use were also similar in both groups. CONCLUSION: We have documented that microsporidiosis with intestinal mucosa disruption is frequent in patients undergoing concomitant anti-tumor necrosis factor/disease-modifying anti-rheumatic drug therapy. Impaired host defenses due to the combination of the underlying disease and the immunosuppressive therapy is the most likely explanation for this finding, and this increased susceptibility reinforces the need for the investigation of microsporidia and implementation of treatment strategies in this population.FAPESPCNPQFederico FoundationWyet

O sentido da vida dos enfermeiros no trabalho em cuidados paliativos: revisão integrativa de literatura

Objetivou-se identificar evidências científicas acerca do sentido da vida dos enfermeiros no trabalho em cuidados paliativos no contexto hospitalar numa perspectiva existencialista. Revisão integrativa conduzida nas bases indexadas LILACS, MEDLINE, BDENF, CINAHL e SCOPUS no período de 2008 a junho de 2019, seguindo as recomendações da ferramenta PRISMA. Foram selecionados 12 artigos internacionais dos quais emergiram três categorias temáticas: “experiências existenciais de enfermeiros que trabalham aos cuidados paliativos”, “os sentidos e significados atribuídos pelos enfermeiros em cuidados paliativos”, e “estratégias de enfrentamento e intervenções apontadas como superação de questões existenciais”. Para que o trabalho dos enfermeiros tenha sentido e represente um valor importante em sua vidas, torna-se importante conhecer as fontes motivadoras que orientam suas decisões, bem como a criação de janelas estratégicas no cuidado que promovam satisfação e desempenho no processo de trabalho e favoreça a cultura do cuidado a pacientes em cuidados paliativos. Descritores: Existencialismo; Espiritualidade; Enfermeiros; Cuidado Paliativo

Vaccination with Recombinant Microneme Proteins Confers Protection against Experimental Toxoplasmosis in Mice

Toxoplasmosis, a zoonotic disease caused by Toxoplasma gondii, is an important public health problem and veterinary concern. Although there is no vaccine for human toxoplasmosis, many attempts have been made to develop one. Promising vaccine candidates utilize proteins, or their genes, from microneme organelle of T. gondii that are involved in the initial stages of host cell invasion by the parasite. In the present study, we used different recombinant microneme proteins (TgMIC1, TgMIC4, or TgMIC6) or combinations of these proteins (TgMIC1-4 and TgMIC1-4-6) to evaluate the immune response and protection against experimental toxoplasmosis in C57BL/6 mice. Vaccination with recombinant TgMIC1, TgMIC4, or TgMIC6 alone conferred partial protection, as demonstrated by reduced brain cyst burden and mortality rates after challenge. Immunization with TgMIC1-4 or TgMIC1-4-6 vaccines provided the most effective protection, since 70% and 80% of mice, respectively, survived to the acute phase of infection. In addition, these vaccinated mice, in comparison to non-vaccinated ones, showed reduced parasite burden by 59% and 68%, respectively. The protective effect was related to the cellular and humoral immune responses induced by vaccination and included the release of Th1 cytokines IFN-γ and IL-12, antigen-stimulated spleen cell proliferation, and production of antigen-specific serum antibodies. Our results demonstrate that microneme proteins are potential vaccines against T. gondii, since their inoculation prevents or decreases the deleterious effects of the infection

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear un derstanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5–7 vast areas of the tropics remain understudied.8–11 In the American tropics, Amazonia stands out as the world’s most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepre sented in biodiversity databases.13–15 To worsen this situation, human-induced modifications16,17 may elim inate pieces of the Amazon’s biodiversity puzzle before we can use them to understand how ecological com munities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple or ganism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region’s vulnerability to environmental change. 15%–18% of the most ne glected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lostinfo:eu-repo/semantics/publishedVersio

Educomunicação e suas áreas de intervenção: Novos paradigmas para o diálogo intercultural

oai:omp.abpeducom.org.br:publicationFormat/1O material aqui divulgado representa, em essência, a contribuição do VII Encontro Brasileiro de Educomunicação ao V Global MIL Week, da UNESCO, ocorrido na ECA/USP, entre 3&nbsp;e 5 de novembro de 2016. Estamos diante de um conjunto de 104 papers executivos, com uma média de entre 7 e 10 páginas, cada um. Com este rico e abundante material, chegamos ao sétimo e-book publicado pela ABPEducom, em seus seis primeiros anos de existência. A especificidade desta obra é a de trazer as “Áreas de Intervenção” do campo da Educomunicação, colocando-as a serviço de uma meta essencial ao agir educomunicativo: o diálogo intercultural, trabalhado na linha do tema geral do evento internacional: Media and Information Literacy: New Paradigms for Intercultural Dialogue

Pervasive gaps in Amazonian ecological research

Biodiversity loss is one of the main challenges of our time,1,2 and attempts to address it require a clear understanding of how ecological communities respond to environmental change across time and space.3,4 While the increasing availability of global databases on ecological communities has advanced our knowledge of biodiversity sensitivity to environmental changes,5,6,7 vast areas of the tropics remain understudied.8,9,10,11 In the American tropics, Amazonia stands out as the world's most diverse rainforest and the primary source of Neotropical biodiversity,12 but it remains among the least known forests in America and is often underrepresented in biodiversity databases.13,14,15 To worsen this situation, human-induced modifications16,17 may eliminate pieces of the Amazon's biodiversity puzzle before we can use them to understand how ecological communities are responding. To increase generalization and applicability of biodiversity knowledge,18,19 it is thus crucial to reduce biases in ecological research, particularly in regions projected to face the most pronounced environmental changes. We integrate ecological community metadata of 7,694 sampling sites for multiple organism groups in a machine learning model framework to map the research probability across the Brazilian Amazonia, while identifying the region's vulnerability to environmental change. 15%–18% of the most neglected areas in ecological research are expected to experience severe climate or land use changes by 2050. This means that unless we take immediate action, we will not be able to establish their current status, much less monitor how it is changing and what is being lost