78 research outputs found
La colonización cisterciense en la Meseta del Duero : El ejemplo de Moreruela : Siglos XII-XIV
Tesis Universidad Complutense de Madrid, 1983.Fac. de Ciencias Políticas y SociologíaTRUEProQuestpu
Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)
Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters.
Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs).
Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001).
Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio
Formas y funciones de la renta: un estudio comparado de la fiscalidadad sectorial en la Edad Media Europea (1050-1350)
Peer reviewe
Las granjas de Moreruela. Notas para el estudio de la colonización cisterciense en la Meseta del Duero
Peer reviewe
Venganza y justicia en el Cantar de Mio Cid
Actas del Congreso Internacional "IX Centenario de la muerte del Cid", celebrado en la Universidad de Alcalá de Henares, los días 19 y 20 de noviembre de 1999Peer reviewe
Vengeance, justice et lutte politique dans l'historiographie castillane du moyen âge
L'analyse, dans une perspective anthropologique, de trois célèbres récits épiques de vengeance qui figurent dans l'Histoire d'Espagne du roi Alphonse le Sage (la Légende des Infants de Lara, le «Roman» de l'Infant Garcia et le Cantar de mio Cid), montre que les narrations sont articulées autour des bonnes et des mauvaises vengeances. Il n'y a pas de condamnation abstraite de la vengeance, ni de proposition de recours à la justice comme moyen plus adéquat de résoudre les conflits, mais des vengeances qui se présentent tantôt comme injustes et injustifiées, tantôt comme dues et légitimes. Une logique de réparation régit ce processus social dans lequel se libèrent les antagonismes suscités par la compétition et la lutte politique, logique qui condamne les trahisons et légitime les répliques qui les punissent. Sont ainsi remises en question deux dichotomies, l'une qui oppose la vengeance à la justice comme formes antithétiques et successives de résolution des conflits, l'autre qui oppose les luttes familiales aux luttes politiques.Peer reviewe
La rhétorique de légitimation seigneuriale dans les fueros de León (XIe-XIIIe siècles)
Peer reviewe
The Rural History of Medieval European Societies. Trends and Perspectives
This collection gathers together a range of scholars who reflect on recent historiographical developments in medieval rural history within their respective countries. Each contribution provides a survey of a recent area of research, as well as documenting its significant results, and offering perspectives for future investigations. This international approach not only provides a deeper insight into how medieval rural studies relates to current debates in the social sciences, but it also highlights the connections between specific national historical traditions and present-day research issues in their historical contexts. By comparing different European regions it is possible to see more clearly the similarities and the differences which lie between them; this volume therefore constitutes a truer means of constructing syntheses and for identifying fruitful lines of future research
Lenguaje y prácticas de negociar en la resolución de conflictos en la sociedad castellano-leonesa medieval
Trabajo presentado en Negociar en la Edad Media: coloquio celebrado en Barcelona los días 14, 15 y 16 de octubre de 2004Peer reviewe
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