Estudio de confiabilidad de transformadores de potencia 33/13.2 kV

En este documento se presentan los resultados de un estudio de confiabilidad de transformadores de potencia realizado a un lote de 63 transformadores 33/13.2 kV pertenecientes a una empresa de distribución colombiana de la cual se cuenta con información operativa para un periodo de 6 años. En la actualidad, en el sistema de distribución colombiano no se cuenta con suficiente información publicada de confiabilidad de componentes para ser aplicada en estudios predictivos a nivel de sistema o para planes de reposición de activos. La confiabilidad del grupo de componentes es analizada a partir de los registros operativos del instante de salida y el instante de restauración, calculando la cadena de Markov que tipifica a un componente, los procesos de Poisson que modelan el arribo de eventos para fallas y reparaciones, las distribuciones de probabilidad asociadas al tiempo para falla y tiempo para reparación y los índices de confiabilidad

OFERTA DE INFORMACIÓN PARA LA USABILIDAD DE REDES SOCIALES Y ACADÉMICAS EN EL CONTEXTO UNIVERSITARIO MEXICANO

The teaching-learning and scientific research processes currently require updated sources and highly relevant information offers to researchers and students. The Universidad Nacional Autónoma de México from the university library system has identified as a problem the low presence of users in social and academic networks. The objectives of the study were: 1) identify the information channels necessary to exchange with the user about their training and information needs and 2) design an information offer based on the criteria of the users to satisfy their investigative, scientific and information needs. from the use of academic social networks. To obtain results, methods were used at the theoretical and empirical levels, essentially a methodology for the design of information offers. The Academia.NET information offer was designed based on the criteria of potential users, using existing services in virtual settings to collect information. It was concluded that digital natives require information offers that enable their development as usersLos procesos de enseñanza aprendizaje e investigación científica actualmente requieren de fuentes actualizadas y ofertas de información altamente relevantes a los investigadores y estudiantes. La Universidad Nacional Autónoma de México desde el sistema de bibliotecas universitarias ha identificado como problemática la poca presencia de los usuarios en las redes sociales y académicas. Se planteó como objetivos del estudio, identificar los canales de información necesarios para intercambiar con el usuario sobre sus necesidades formativas e informativas y diseñar una oferta de información a partir del criterio de los usuarios para satisfacer sus necesidades investigativas, científicas e informativas a partir del uso de las redes sociales académicas. Para la obtención de resultados se emplearon métodos en los niveles teóricos y empíricos, esencialmente una metodología para el diseño de ofertas de información. Se diseñó la oferta de información Academia.NET a partir de los criterios de los usuarios potenciales, empleando servicios ya existentes en escenarios virtuales para recoger información. Se concluyó que los nativos digitales requieren de ofertas de información que les posibilite su desarrollo como usuario

EuroFlow Lymphoid Screening Tube (LST) data base for automated identification of blood lymphocyte subsets

In recent years the volume and complexity of flow cytometry data has increased substantially. This has led to a greater number of identifiable cell populations in a single measurement. Consequently, new gating strategies and new approaches for cell population definition are required. Here we describe how the EuroFlow Lymphoid Screening Tube (LST) reference data base for peripheral blood (PB) samples was designed, constructed and validated for automated gating of the distinct lymphoid (and myeloid) subsets in PB of patients with chronic lymphoproliferative disorders (CLPD). A total of 46 healthy/reactive PB samples which fulfilled predefined technical requirements, were used to construct the LST-PB reference data base. In addition, another set of 92 PB samples (corresponding to 10 healthy subjects, 51 B-cell CLPD and 31 T/NK-cell CLPD patients), were used to validate the automated gating and cell-population labeling tools with the Infinicyt software. An overall high performance of the LST-PB data base was observed with a median percentage of alarmed cellular events of 0.8% in 10 healthy donor samples and of 44.4% in CLPD data files containing 49.8% (range: 1.3–96%) tumor cells. The higher percent of alarmed cellular events in every CLPD sample was due to aberrant phenotypes (75.6% cases) and/or to abnormally increased cell counts (86.6% samples). All 18 (22%) data files that only displayed numerical alterations, corresponded to T/NK-cell CLPD cases which showed a lower incidence of aberrant phenotypes (41%) vs B-cell CLPD cases (100%). Comparison between automated vs expert-bases manual classification of normal (r2 = 0.96) and tumor cell populations (rho = 0.99) showed a high degree of correlation. In summary, our results show that automated gating of cell populations based on the EuroFlow LST-PB data base provides an innovative, reliable and reproducible tool for fast and simplified identification of normal vs pathological B and T/NK lymphocytes in PB of CLPD patients

EuroFlow Lymphoid Screening Tube (LST) data base for automated identification of blood lymphocyte subsets

In recent years the volume and complexity of flow cytometry data has increased substantially. This has led to a greater number of identifiable cell populations in a single measurement. Consequently, new gating strategies and new approaches for cell population definition are required. Here we describe how the EuroFlow Lymphoid Screening Tube (LST) reference data base for peripheral blood (PB) samples was designed, constructed and validated for automated gating of the distinct lymphoid (and myeloid) subsets in PB of patients with chronic lymphoproliferative disorders (CLPD). A total of 46 healthy/reactive PB samples which fulfilled predefined technical requirements, were used to construct the LST-PB reference data base. In addition, another set of 92 PB samples (corresponding to 10 healthy subjects, 51 B-cell CLPD and 31 T/NK-cell CLPD patients), were used to validate the automated gating and cell-population labeling tools with the Infinicyt software. An overall high performance of the LST-PB data base was observed with a median percentage of alarmed cellular events of 0.8% in 10 healthy donor samples and of 44.4% in CLPD data files containing 49.8% (range: 1.3–96%) tumor cells. The higher percent of alarmed cellular events in every CLPD sample was due to aberrant phenotypes (75.6% cases) and/or to abnormally increased cell counts (86.6% samples). All 18 (22%) data files that only displayed numerical alterations, corresponded to T/NK-cell CLPD cases which showed a lower incidence of aberrant phenotypes (41%) vs B-cell CLPD cases (100%). Comparison between automated vs expert-bases manual classification of normal (r2 = 0.96) and tumor cell populations (rho = 0.99) showed a high degree of correlation. In summary, our results show that automated gating of cell populations based on the EuroFlow LST-PB data base provides an innovative, reliable and reproducible tool for fast and simplified identification of normal vs pathological B and T/NK lymphocytes in PB of CLPD patients