Twisted Tales: Insights into Genome Diversity of Ciliates Using Single-Cell 'Omics.

The emergence of robust single-cell 'omics techniques enables studies of uncultivable species, allowing for the (re)discovery of diverse genomic features. In this study, we combine single-cell genomics and transcriptomics to explore genome evolution in ciliates (a > 1 Gy old clade). Analysis of the data resulting from these single-cell 'omics approaches show: 1) the description of the ciliates in the class Karyorelictea as "primitive" is inaccurate because their somatic macronuclei contain loci of varying copy number (i.e., they have been processed by genome rearrangements from the zygotic nucleus); 2) gene-sized somatic chromosomes exist in the class Litostomatea, consistent with Balbiani's (1890) observation of giant chromosomes in this lineage; and 3) gene scrambling exists in the underexplored Postciliodesmatophora (the classes Heterotrichea and Karyorelictea, abbreviated here as the Po-clade), one of two major clades of ciliates. Together these data highlight the complex evolutionary patterns underlying germline genome architectures in ciliates and provide a basis for further exploration of principles of genome evolution in diverse microbial lineages

Preparation of Dimeric Monopentamethylcyclopentadienyltitanium(III) Dihalides and Related Derivatives

Ministerio de Ciencia, Innovación y Universidades de España, Ministerio de Economía y Competitividad de España, Universidad de Alcal

Homo and Heteropolymetallic Group 4 Molecular Nitrides

Ministerio de Economía y Competitividad de España, Universidad de Alcal

Molecular Nitrides with Titanium and Group 13-15 Elements

MINISTERIO DE EDUCACIÓN Y CIENCIA, COMUNIDAD DE MADRID, UNIVERSIDAD DE ALCAL

Enantiomer stability and combined toxicity of duloxetine and econazole on Daphnia magna using real concentrations determined by capillary electrophoresis

Ministry of Economy and Competitiveness (Spain) CTQ2013-48740-P CTQ2016-76368-P BES-2014-070532 University of Alcal

Cube-Type Nitrido Complexes Containing Titanium and Alkali/Alkaline-Earth Metals

(M = Ca, Sr) have been determined. The properties and solid-state structures of the azaheterometallocubane complexes bearing alkali and alkaline-earth metals are discussed.Ministerio de Ciencia y Tecnología de España, Comunidad de Madrid, Universidad de Alcal

Jes\ufas Duce Garc\ueda, Antolog\ueda de aut\uf3matas en los libros de caballer\uedas castellanos, Alcal\ue1 de Henares, Universidad de Alcal\ue1 / Instituto Universitario de Investigaci\uf3n Miguel de Cervantes, 2016

Recensione di: Jes\ufas Duce Garc\ueda, Antolog\ueda de aut\uf3matas en los libros de caballer\uedas castellanos, Alcal\ue1 de Henares, Universidad de Alcal\ue1 / Instituto Universitario de Investigaci\uf3n Miguel de Cervantes, 2016

Unexpected N-C bond fission of fused N-alkylbenzimidazolium salts. A new approach to pyrido[1,2-a]- or pyridazino[1,6-a]benzimidazoles

The reaction of N-carboxymethylpyrido[1,2-a]- and pyridazino[1,6-a]benzimidazolium salts with thionyl chloride resulted in an N-C bond fission, yielding the corresponding pyrido[1,2-a]- and pyridazino[1,6-a]benzimidazoles. A similar dealkylation process was observed when analogous N-propargylic derivatives were treated with Cu (II) acetate.Universidad de Alcal

Publishing performance in economics: Spanish rankings (1990-1999).

This paper contributes to the growing literature that analyses the Spanish publishing performance in Economics throughout the 1990s. Several bibliometric indicators are used in order to provide Spanish rankings (of both institutions and individual authors) based on Econlit journals. Further, lists of the ten most influential authors and articles over that period, in terms of citations, are reported.Rankings; economics; Bibliometric indicators;