138 research outputs found
Dynamic analysis of shear deformable plates using the dual reciprocity method
The Dual Reciprocity Method is a popular mathematical technique to treat domain integrals in the boundary element method (BEM). This technique has been used to treat inertial integrals in the dynamic thin plate bending analysis using a direct formulation of the BEM based on the elastostatic fundamental solution of the problem. In this work, this approach was applied for the dynamic analysis of shear deformable plates based on the Reissner plate bending theory, considering the rotary inertia of the plate. Three kinds of problems: modal, harmonic and transient dynamic analysis, were analyzed. Numerical examples are presented to demonstrate the efficiency and accuracy of the proposed formulation. © 2011 Elsevier Ltd. All rights reserve
Magnetization in quasiperiodic magnetic multilayers with biquadratic exchange coupling
A theoretical study of the magnetization curves of quasiperiodic magnetic
multilayers is presented. We consider structures composed by ferromagnetic
films (Fe) with interfilm exchange coupling provided by intervening
nonferromagnetic layers (Cr). The theory is based on a realistic
phenomenological model, which includes the following contributions to the free
magnetic energy: Zeeman, cubic anisotropy, bilinear and biquadratic exchange
energies. The experimental parameters used here are based on experimental data
recently reported, which contain sufficiently strong biquadratic exchange
coupling.Comment: 6 EPS figures, REVTeX, accepted for publication in Journal of Applied
Physic
An adaptive cross approximation (ACA) for the extended boundary element method (XBEM) in anisotropic materials
The extended boundary element method (XBEM) is a modification from the standard BEM, where enrichment functions are embedded into the BEM formulation. The results obtained with this method were seen to be accurate and stable, being especially useful for fracture problems. However, the method suffers from the presence of a linear system containing unsymmetric and fully populated matrices which needs to be solved in order to get the solution of the boundary problem. This can be computationally expensive for problems dealing with multiple cracks for instance. Adaptive cross approximation (ACA) is used to reduce the number of operations necessary to solve the linear system of equations for a fracture problem with an anisotropic material
A well simulator for homogeneous reservoirs based on formulations of the isogeometric boundary element method
The development of a simulator for homogeneous reservoirs with application in producer wells (represented by a sink) and the aquifer analysis is obtained by combining the Boundary Element Method (BEM), the Isogeometric Formulation using NURBS (Non Uniform Rational B-Spline) as shape functions, and also the Axisymmetric Formulation. The Isogeometric Formulation makes the discretization of geometric model (mesh generation), which is the step of numerical analysis that is more time consuming for the engineer, be no longer necessary, since the same functions that describe the geometry also approximate the field variables in the BEM. In other words, the same discretization used in the geometric model, generated in CAD (Computer Aided Design) modeling programs, also is used by the BEM. The oil and water reservoirs, as simplified models for validation of the new mathematical methodology, can be fully represented by the analysis of a plane passing through the axis of rotational (axial) symmetry. The dimension of the problem is reduced from three to two dimensions: radial and axial directions only, and all variables in the circumferential direction are assumed to be constant. When the geometry and the problem variables are both axisymmetric, then the problem is considered fully axisymmetric. The isogeometric and axisymmetric formulations are coupled to obtain the well simulator for the single and double phase case, i.e. one or two incompressible fluids inside the reservoir. The determination of boundary conditions for the model, including the analysis of fluids interface movement, is also presented. The final code is a new tool for the analysis of gas/water coning phenomenon and quick drawdown problem in homogeneous reservoirs, as validation models. Validation of the results is carried out by comparing with others numerical methods and analytical results
Influence of the biquadratic interlayer coupling in the specific heat of Fibonacci magnetic multilayers
A theoretical study of the specific heat C(T) as a function of temperature in
Fibonacci magnetic superlattices is presented. We consider quasiperiodic
structures composed of ferromagnetic films, each described by the Heisenberg
model, with biquadratic and bilinear coupling between them. We have taken the
ratios between the biquadratic and bilinear exchange terms according to
experimental data recently measured for different regions of their regime.
Although some previous properties of the spin wave specific heat are also
reproduced here, new features appear in this case, the most important of them
being an interesting broken-symmetry related to the interlayer biquadratic
term.Comment: 13 pages, 4 ps figures, Submitted to Physica
The DNA electronic specific heat at low temperature: The role of aperiodicity
AbstractThe electronic specific heat spectra at constant volume (CV) of a long-range correlated extended ladder model, mimicking a DNA molecule, is theoretically analyzed for a stacked array of a double-stranded structure made up from the nucleotides guanine G, adenine A, cytosine C and thymine T. The role of the aperiodicity on CV is discussed, considering two different nucleotide arrangements with increasing disorder, namely the Fibonacci and the Rudin–Shapiro quasiperiodic structures. Comparisons are made for different values of the band fillings, considering also a finite segment of natural DNA, as part of the human chromosome Ch22
Challenges in the rabbit haemorrhagic disease 2 (RHDV2) molecular diagnosis of vaccinated rabbits
Molecular methods are fundamental tools for the diagnosis of viral infections. While interpretation of
results is straightforward for unvaccinated animals, where positivity represents ongoing or past
infections, the presence of vaccine virus in the tissues of recently vaccinated animals may mislead
diagnosis.
In this study, we investigated the interference of RHDV2 vaccination in the results of a RT-qPCR for
RHDV2 detection, and possible associations between mean Cq values of
five animal groups differing in
age, vaccination status and origin (domestic/wild).
Viral sequences from vaccinated rabbits that died of RHDV2 infection (n = 14) were compared with the
sequences from the commercial vaccines used in those animals. Group Cq means were compared through
Independent t-test and One-way ANOVA.
We proved that RHDV2 vaccine-RNA is not detected by the RT-qPCR as early as 15 days post-
vaccination, an important fact in assisting results interpretation for diagnosis.
Cq values of vaccinated and non-vaccinated infected domestic adults showed a statistically significant
difference (p
<
0.05), demonstrating that vaccination-induced immunity reduces viral loads and delays
disease progression. Contrarily, in vaccinated young rabbits higher viral loads were registered compared
to non-vaccinated kittens. No significant variation (p = 0.3824) was observed between viral loads of non-
vaccinated domestic and wild RHDV2-victimised rabbits. Although the reduced number of vaccinated
young animals analysed hampered a robust statistical analysis, this occurrence suggests that passively
acquired maternal antibodies may inhibit the active immune response to vaccination, delaying
protection and favouring disease progression.
Our
finding emphasises the importance of adapting kitten RHDV2 vaccination schedules to circumvent
this interference phenomenon
A topological optimization procedure applied to multiple region problems with embedded sources
The main objective of this work is the application of the topological optimization procedure to heat transfer problems considering multiple materials. The topological derivative (DT) is employed for evaluating the domain sensitivity when perturbed by inserting a small inclusion. Electronic components such as printed circuit boards (PCBs) are an important area for the application of topological optimization. Generally, geometrical optimization involving heat transfer in PCBs considers only isotropic behavior and/or a single material. Multiple domains with anisotropic characteristics take an important role on many industrial products, for instance when considering PCBs which are often connected to other components of different materials. In this sense, a methodology for solving topological optimization problems considering anisotropy and multiple regions with embedded heat sources is developed in this paper. A direct boundary element method (BEM) is employed for solving the proposed numerical problem.CNPQ – Brazil through the Science without Borders program and from Brunel University
Resonant Photonic Quasicrystalline and Aperiodic Structures
We have theoretically studied propagation of exciton-polaritons in
deterministic aperiodic multiple-quantum-well structures, particularly, in the
Fibonacci and Thue-Morse chains. The attention is concentrated on the
structures tuned to the resonant Bragg condition with two-dimensional
quantum-well exciton. The superradiant or photonic-quasicrystal regimes are
realized in these structures depending on the number of the wells. The
developed theory based on the two-wave approximation allows one to describe
analytically the exact transfer-matrix computations for transmittance and
reflectance spectra in the whole frequency range except for a narrow region
near the exciton resonance. In this region the optical spectra and the
exciton-polariton dispersion demonstrate scaling invariance and self-similarity
which can be interpreted in terms of the ``band-edge'' cycle of the trace map,
in the case of Fibonacci structures, and in terms of zero reflection
frequencies, in the case of Thue-Morse structures.Comment: 13 pages, 9 figures, submitted to Phys. Rev.
Progression of rabbit haemorrhagic disease virus 2 upon vaccination in an industrial rabbitry: a laboratorial approach
[EN] Rabbit haemorrhagic disease virus 2 (RHDV2) emerged recently in several European countries, leading to extensive economic losses in the industry. In response to this new infection, specific inactivated vaccines were developed in Europe and full and rapid setup of protective immunity induced by vaccination was reported. However, data on the efficacy of these vaccines in an ongoing-infection scenario is unavailable. In this study we investigated an infected RHDV2 indoor industrial meat rabbitry, where fatalities continued to occur after the implementation of the RHDV2 vaccination, introduced to control the disease. The aim of this study was to understand if these mortalities were RHDV2-related, to discover if the dead animals showed any common features such as age or time distance from vaccination, and to identify the source of the outbreak. Anatomo-pathological analysis of vaccinated animals with the virus showed lesions compatible with systemic haemorrhagic disease and RHDV2-RNA was detected in 85.7% of the animals tested. Sequencing of the vp60 gene amplified from liver samples led to the recognition of RHDV2 field strains demonstrating that after the implementation of vaccination, RHDV2 continued to circulate in the premises and to cause sporadic deaths. A nearby, semi-intensive, RHDV2 infected farm belonging to the same owner was identified as the most probable source of the virus. The main risk factors for virus introduction in these two industries were identified. Despite the virus being able to infect a few of the vaccinated rabbits, the significant decrease in mortality rate observed in vaccinated adult rabbits clearly reflects the efficacy of the vaccination. Nonetheless, the time taken to control the infection also highlights the importance of RHDV2 vaccination prior to the first contact with the virus, highly recommendable in endemic areas, to mitigate the infection’s impact on the industry.The authors would like to thank Dr. Fidélia Aboim (Municipal veterinarian) for gathering information on the mortality of wild rabbits in several legal hunting parks and to Maria João Teixeira, Fátima Cordeiro and Ricardino Ferreira for their technical assistance. This study was partially funded by a grant from the Fundação para a Ciência e Tecnologia (FCT) SFRH/79225/2011.Carvalho, C.; Duarte, E.; Monteiro, J.; Afonso, C.; Pacheco, J.; Carvalho, P.; Mendonça, P.... (2017). Progression of rabbit haemorrhagic disease virus 2 upon vaccination in an industrial rabbitry: a laboratorial approach. World Rabbit Science. 25(1):73-85. doi:10.4995/wrs.2017.5708.SWORD738525
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