Single-occupancy simulator for ambient intelligent environment

In this paper, the simulation of an occupant’s behaviour in a single-occupant ambient intelligent environment is addressed. The algorithm of the simulator is designed flexible enough to accept different environmental profiles including the number of areas and the connections between them along with different occupant’s profiles including expected daily occupancy pattern of him/her and the uncertainty of his/her behaviour to follow this occupancy pattern. The generated occupancy signal by the simulator represents the occupancy of areas by assuming a signal level for the occupancy of each area in a single-occupant environment with the resolution of one minute in a whole day activity of the occupant in the environment. The validity of the simulator will be verified by tuning the simulator’s parameters to occupancy data collected by sensory agents from a real equivalent environment. By applying the generated data from this simulator to the data mining techniques, the ability of different techniques will be investigated

Occupancy monitoring and prediction in ambient intelligent environment

Occupancy monitoring and prediction as an influential factor in the extraction of occupants' behavioural patterns for the realisation of ambient intelligent environments is addressed in this research. The proposed occupancy monitoring technique uses occupancy detection sensors with unobtrusive features to monitor occupancy in the environment. Initially the occupancy detection is conducted for a purely single-occupant environment. Then, it is extended to the multipleoccupant environment and associated problems are investigated. Along with the occupancy monitoring, it is aimed to supply prediction techniques with a suitable occupancy signal as the input which can enhance efforts in developing ambient intelligent environments. By predicting the occupancy pattern of monitored occupants, safety, security, the convenience of occupants, and energy saving can be improved. Elderly care and supporting people with health problems like dementia and Alzheimer disease are amongst the applications of such an environment. In the research, environments are considered in different scenarios based on the complexity of the problem including single-occupant and multiple-occupant scenarios. Using simple sensory devices instead of visual equipment without any impact on privacy and her/his normal daily activity, an occupant is monitored in a living or working environment in the single-occupant scenario. ZigBee wireless communication technology is used to collect signals from sensory devices such as motion detection sensors and door contact sensors. All these technologies together including sensors, wireless communication, and tagging are integrated as a wireless sensory agent

Expanded Perlite-Polyphosphoric Acid (EP-PPA) as a Low-Cost Heterogeneous Solid Acid Catalyst for Green and Metal-Free Synthesis of Nitriles from Aldehydes

Expanded Perlite-Polyphosphoric Acid (EP-PPA) as a solid acid catalyst reported earlier by our group, has been found to be very effective for direct transformation of aldehydes into nitriles. The aforesaid catalyst exhibited excellent catalytic activity in high yielding preparation of a wide range of nitriles under solvent-free conditions. Furthermore, the method consistently has the advantages of environmental acceptability, short reaction times, excellent functional group compatibility and easy experimental and work-up procedures. Importantly, catalyst reusability up to six runs with little loss of catalytic activity made the present procedure better than the most previously reported protocols

Planejamento de cenário para tecnologia emergente (big data & cloud) no setor de saúde

The emergence of big data, as well as advancements in data science approaches and technology, is providing pharmaceutical companies with an opportunity to gain novel insights that can enhance and accelerate drug development. It will increasingly help government, health agencies, players, and providers to make decisions about such issues as drug discovery, patient access, and marketing. In this paper we use scenario planning tools and system dynamic to evaluate the impact of emergent technology such as big data &cloud &in healthcare industry. In this case we have four scenarios of big data and emergent tech transformation in Iran health care industry.La aparición de grandes volúmenes de datos, así como los avances en los enfoques y la tecnología de la ciencia de datos, brindan a las compañías farmacéuticas la oportunidad de obtener información novedosa que puede mejorar y acelerar el desarrollo de medicamentos. Ayudará cada vez más al gobierno, agencias de salud, jugadores y proveedores a tomar decisiones sobre temas como el descubrimiento de medicamentos, el acceso de pacientes y la comercialización. En este documento, utilizamos herramientas de planificación de escenarios y dinámica del sistema para evaluar el impacto de la tecnología emergente, como Big Data y nube, y en la industria de la salud. En este caso, tenemos cuatro escenarios de big data y transformación de tecnología emergente en la industria del cuidado de la salud de IránO surgimento de grandes volumes de dados, bem como os avanços nas abordagens e tecnologias da ciência de dados, estão proporcionando às empresas farmacêuticas uma oportunidade de obter novos insights que possam melhorar e acelerar o desenvolvimento de medicamentos. Ajudará cada vez mais o governo, as agências de saúde, os atores e os provedores a tomar decisões sobre questões como descoberta de medicamentos, acesso de pacientes e marketing. Neste documento, usamos ferramentas de planejamento de cenário e dinâmica de sistema para avaliar o impacto de tecnologias emergentes, como big data e nuvem e no setor de saúde. Neste caso, temos quatro cenários de big data e transformação tecnológica emergente na indústria de saúde do Irã

Sun-light-driven Suzuki-Miyaura Cross-coupling using a Novel Superparamagnetic Metal-organic Framework Catalyst

A prominent catalytic activity for sun-light driven Suzuki-Miyaura cross-coupling reaction has been shown in the presence of superparamagnetic core-shell metal-organic framework (Fe3O4@Ni-Co-BTC NPs) (with particle size 10–47 nm) and unique bimetallic core-shell nanostructure). Various aryl halides with electron-donating or electron-withdrawing substituents were coupled with different arylboronic acids towards corresponding products at ambient temperature in H2O. The results of photocatalysis demonstrate that Fe3O4@Ni-Co-BTC NPs is a good photocatalyst under sun light irradiation with high efficiency, chemoselectivity and functional group tolerance. This magnetic separable nanostructured catalyst can be reused more than six times with minimal loss of catalytic activity rendering this catalyst long-term stability. The results acquired in the present study can serve as inspiration for the further exploitation of the sun-light-driven cross-coupling reaction under mild conditions. This work is licensed under a Creative Commons Attribution 4.0 International License

Direct and Facile Synthesis of Acyl Isothiocyanates from Carboxylic Acids Using Trichloroisocyanuric Acid/Triphenylphosphine System

A mild, efficient, and practical method for one-step synthesis of alkanoyl and aroyl isothiocyanates from carboxylic acids using a safe and inexpensive mixed reagent, trichloroisocyanuric acid/triphenyl¬phosphine is described at room temperature. Availability of the reagents and easy workup of the reaction make this method attractive for organic chemists

On the Category of EQ-algebras

In this paper, we studied the category of EQ-algebras and showed that it is complete, but it is not cocomplete, in general. We proved that multiplicatively relative EQ-algebras have coequlizers and we calculated coproduct and pushout in a special case. Also, we constructed a free EQ-algebra on a singleton

Conformational behaviour of mannuronic acid based azasugars

A set of mannuronic acid based iminosugars, comprising the C-5-carboxylic acid, -methyl ester and -amide analogues of 1-deoxymannorjirimicin (DMJ), was synthesized and their pH dependent conformational behavior studied. Under acidic conditions the methyl ester and the carboxylic acid took up an "inverted" 1C4 chair conformation as opposed to the "normal" 4C1 chair at basic pH. This conformational change is explained by the stereoelectronic effects of the ring substituents and it parallels the behavior of the mannuronic acid ester oxocarbenium ion. Because of this solution phase behavior, the mannuronic acid ester azasugar was probed as an inhibitor for a Caulobacter GH47 mannosidase that hydrolyzes its substrates following a reaction itinerary that proceeds through a 3H4 transition state. No binding was observed for the mannuronic acid ester azasugar, but sub-atomic resolution data were obtained for the DMJ-CkGH47 complex, showing two conformations, 3S1 and 1C4, for the DMJ inhibitor