92 research outputs found

    Coefficient multipliers on spaces of vector-valued entire Dirichlet series

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    summary:The spaces of entire functions represented by Dirichlet series have been studied by Hussein and Kamthan and others. In the present paper we consider the space XX of all entire functions defined by vector-valued Dirichlet series and study the properties of a sequence space which is defined using the type of an entire function represented by vector-valued Dirichlet series. The main result concerns with obtaining the nature of the dual space of this sequence space and coefficient multipliers for some classes of vector-valued Dirichlet series

    Modified e-slotted patch antenna for WLAN/Wi-Max satellite applications

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    A low profile modified e-slotted microstrip antenna is proposed for multiple wireless communication applications. The performance of antenna is measured in terms of return loss, current distribution. The effect of variation of height of substrate on antenna impedance bandwidth is also studied. The antenna with overall size 30Ă—50Ă—.8m.m.3 resonates at eight frequencies which covers some important applications like GPS, wireless local area network (WLAN), worldwide interoperability for microwave access (WiMax), Satellite communication etc. The proposed antenna structure offers great advantages due to compact size, simple structure and multiple applications. The multi band antenna was designed and optimized using ansoft HFSS v13 simulator. The simulated result is good agreement with measured result

    Materanal and neonatal outcomes of triplet gestation in a tertiary care centre: a retrospective study

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    Background: A significant rise in triplet pregnancy rate has occurred recently. This rise is of concern, as these infants are frequently reported as a risk factor of adverse outcome. The aim of this study was to retrospectively study the outcomes of triplet births.Methods: A retrospective study was undertaken to analyze the clinical data of all patients with triplet gestation admitted to the labour room of Dr. Baba Saheb Ambedkar Hospital, Delhi to study the maternal and fetal outcomes. Authors retrospectively observed and analyzed the database to examine triplet gestations delivered between January 2014 and December 2018.Results: Over the five-year study period, there were total 44,011 deliveries. Out of these, there were 35 (0.079%) triplet pregnancies. Of all the triplet pregnancies studied 80% resulted from ovulation induction and assisted reproductive technology. The mean gestational age at delivery was 31.6±3.0 weeks, and the mean birth weight was 1,594±460 gm. The most common maternal complications were Preterm labour in 32 pregnancies (92%), anemia in 17 (49%), pre-eclampsia in 11 (31%), post-partum hemorrhage in 8 (22%). Of the total deliveries neonatal complications included Respiratory distress syndrome in 44 (42.2%), Hyperbilirubinemia in 41 (39%), Intrauterine growth restriction in 19 (18.1%). The perinatal mortality rate was 10.5%.Conclusions: Higher order pregnancies are associated with maternal and neonatal complications. These high risk women need more care and the neonates require intensive care and monitoring after birth, most commonly due to prematurity and low birth weight

    Quantification of phenolic compounds in Leucas mollissima Wall. ex Benth through HPTLC and validation of its antioxidant potential

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    The present study deals with quantification of phenolic compounds by a simple, rapid, sensitive and selective high-performance thin-layer chromatographic (HPTLC) method and evaluation of its traditional claims. A chromatographic separation was performed by using a combination of toluene: ethyl acetate: formic acid (70:30:10, v/v/v) as a mobile phase. A densitometric absorption mode has been used for the estimation of catechin and vanillic acid by comparing the peak area against the standard at wavelength 220 nm. The amount of catechin and vanillic acid was found to be 0.15% and 0.45% dry weight basis. The developed method was validated and found to be specific, linear, precise and accurate as per the International Conference on Harmonization guidelines. Antioxidant potential was evaluated by five different models having variable mechanisms of action viz., total phenolic and flavonoid content, reducing power assay, DPPH assay, deoxyribose assay and total antioxidant potential. In vitro potential data reveals that the species has significant potential and may be used as an alternative plant in future for the treatment of diabetic condition. However, identified bioactive compounds (catechin and vanillic acid) may be used as a reference tool for proper recognition and confirmation of right plant material and monitoring of batch-to-batch consistency of finished herbal products using Leucas mollissima as an ingredient

    HOME: A histogram based machine learning approach for effective identification of differentially methylated regions

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    Background The development of whole genome bisulfite sequencing has made it possible to identify methylation differences at single base resolution throughout an entire genome. However, a persistent challenge in DNA methylome analysis is the accurate identification of differentially methylated regions (DMRs) between samples. Sensitive and specific identification of DMRs among different conditions requires accurate and efficient algorithms, and while various tools have been developed to tackle this problem, they frequently suffer from inaccurate DMR boundary identification and high false positive rate. Results We present a novel Histogram Of MEthylation (HOME) based method that takes into account the inherent difference in the distribution of methylation levels between DMRs and non-DMRs to discriminate between the two using a Support Vector Machine. We show that generated features used by HOME are dataset-independent such that a classifier trained on, for example, a mouse methylome training set of regions of differentially accessible chromatin, can be applied to any other organism’s dataset and identify accurate DMRs. We demonstrate that DMRs identified by HOME exhibit higher association with biologically relevant genes, processes, and regulatory events compared to the existing methods. Moreover, HOME provides additional functionalities lacking in most of the current DMR finders such as DMR identification in non-CG context and time series analysis. HOME is freely available at https://github.com/ListerLab/HOME . Conclusion HOME produces more accurate DMRs than the current state-of-the-art methods on both simulated and biological datasets. The broad applicability of HOME to identify accurate DMRs in genomic data from any organism will have a significant impact upon expanding our knowledge of how DNA methylation dynamics affect cell development and differentiation.This work was supported by the Australian Research Council (ARC) Centre of Excellence program in Plant Energy Biology (CE140100008). RL was supported by a Sylvia and Charles Viertel Senior Medical Research Fellowship, ARC Future Fellowship (FT120100862), and Howard Hughes Medical Institute International Research Scholarship (RL

    Quantification of phenolic compounds in Leucas mollissima Wall. ex Benth through HPTLC and validation of its antioxidant potential

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    694-699The present study deals with quantification of phenolic compounds by a simple, rapid, sensitive and selective high-performance thin-layer chromatographic (HPTLC) method and evaluation of its traditional claims. A chromatographic separation was performed by using a combination of toluene: ethyl acetate: formic acid (70:30:10, v/v/v) as a mobile phase. A densitometric absorption mode has been used for the estimation of catechin and vanillic acid by comparing the peak area against the standard at wavelength 220 nm. The amount of catechin and vanillic acid was found to be 0.15% and 0.45% dry weight basis. The developed method was validated and found to be specific, linear, precise and accurate as per the International Conference on Harmonization guidelines. Antioxidant potential was evaluated by five different models having variable mechanisms of action viz., total phenolic and flavonoid content, reducing power assay, DPPH assay, deoxyribose assay and total antioxidant potential. In vitro potential data reveals that the species has significant potential and may be used as an alternative plant in future for the treatment of diabetic condition. However, identified bioactive compounds (catechin and vanillic acid) may be used as a reference tool for proper recognition and confirmation of right plant material and monitoring of batch-to-batch consistency of finished herbal products using Leucas mollissima as an ingredient

    ANTI-DIABETIC ACTIVITY OF TRADITIONAL POLYHERBAL FORMULATION: DEVELOPMENT AND EVALUATION

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    Herbal therapy has emerged as a prominent therapeutic approach for a wide range of ailments. In tandem with a nutritious diet and lifestyle, these interventions aim to address certain health objectives by supplying each cell with the most suitable and advantageous nourishment. There exists a botanical alternative for each synthetic medicine now available. Material and Methods: The herbs utilized in the formulation were obtained from reputable vendors and subsequently verified by Department of Life Sciences, Garden City University, Bengaluru, Karnataka, India. For the purpose of standardizing raw materials, shade-dried powdered plant parts from the plants Berberis aristata (dried stem), Terminalia chebula (pericarp of matured fruit), Emblica officinalis (pericarp of dried mature fruit), Terminalalia belerica (pericarp of dried ripe fruit), and Cyperus rotundus (dried rhizome) are used. Results: Blood glucose and lipid profiles were taken first thing in the morning. The formulation had a significant impact when compared to the typical range before diabetes was introduced. Total cholesterol, bad LDL cholesterol, and bad triglyceride levels were all reduced while HDL levels were increased. The phytochemical investigation backed up the claim that flavonoids were present. This may explain why it has such a dramatic impact on treating diabetes. It is recommended that future clinical trials be conducted in Human Volunteers, and that stability studies be conducted on the manufactured polyherbal capsules. Conclusion: The oldest type of therapy, herbal remedies are used to identify and treat illnesses. An animal model was used to assess the antidiabetic potency of five raw materials that were chosen for formulation into polyherbal capsules. The capsules significantly improved the lipid profile and fasting blood glucose indices, as well as their anti-diabetic efficacy. Future use is advised to pursue additional stability research and clinical trials

    Aromatic Rice of India: It’s Types and Breeding Strategies

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    The coalescence of organoleptic traits viz., pleasant aroma, cooked rice texture, and taste make aromatic rice unique and distinguished from non-aromatic rice. Aromatic rice is cultivated in every rice growing country; with each country has its own indigenous collection. International trade of rice is dominated by Indica (long grained), Japonica (short grained), aromatic rice (Basmati and Jasmine) and glutinous rice; amidst which, Basmati types from India and Pakistan; and Jasmine types from Thailand have phenomenal demand. In India all types of aromatic rice are cultivated based on Kernel length; short, medium, long and very long grained. Basmati varieties own the major market, while other types of aromatic rice besides Basmati are popular in local market only. The country inherits rich diversity of aromatic rice germplasm; with more than 300 different types, each of the rice growing states of India has its own locally popular aromatic rice varieties. India a country where two third of its population consume rice as part of their daily food; aromatic rice always remain their favorite. Basmati, by virtue of its excellent qualities it dominates both national and international market. Every year, Basmati ranks first in respect of foreign exchange earned from the export of agricultural products from India (APEDA). The phenomenal demand and export figures have augmented Basmati Breeding program. However, only few aromatic varieties are cultivated depending on their demand, and their breeding program is also limited. In India, Basmati has over-shadowed other types of aromatic rice in market and in plant breeding programs too. Breeding for Basmati varieties is undertaken by prime agricultural institutions of India. The country regulates quality standards and development of Basmati varieties with the help of Export of Basmati Rice (Quality Control and Inspection) Rules 2003; Agricultural and Processed Food Products Export Development Authority (APEDA); and Basmati Export Development Foundation (BEDF). However, no such initiatives have been taken to promote the development of other aromatic rice varieties of India besides Basmati

    Utilisation, equity and determinants of full antenatal care in India: analysis from the National Family Health Survey 4

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    Objectives: We examined the utilisation, equity and determinants of full antenatal care (ANC), defined as 4 or more antenatal visits, at least one tetanus toxoid (TT) injection and consumption of iron folic acid (IFA) for a minimum of 100 days, in India. Methods: We analysed a sample of 190,898 women from India’s National Family Health Survey 4. Concentration curves and concentration index were used to assess equity in full ANC utilisation. Multivariable logistic regression model was used to examine the factors associated with full ANC utilisation. Results: In India, 21% of pregnant women utilised full ANC, ranging from 2.3–65.9% across states. Overall, 51.6% had 4 or more ANC visits, 30.8% consumed IFA for atleast 100 days, and 91.1% had one or more doses of tetanus toxoid. Full ANC utilisation was inequitable across place of residence, caste and maternal education. Registration of pregnancy, utilisation of government’s Integrated Child Development Services (ICDS) and health insurance coverage were associated with higher odds of full ANC utilisation. Lower maternal education, lower wealth quintile(s), lack of father’s participation during antenatal visits, higher birth order, teenage and unintended pregnancy were associated with lower odds of full ANC utilisation. Conclusions: Full ANC utilisation in India was inadequate and inequitable. Although half of the women did not receive the minimum recommended ANC visits, the utilisation of TT immunisation was almost universal. The positive association of full ANC with ICDS utilisation and child’s father involvement may be leveraged for increasing the uptake of full ANC. Strategies to address the socio-demographic factors associated with low and inequitable utilisation of full ANC are imperative for strengthening India’s maternal health program.publishedVersio
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