Facile, catalyst-free, microwave-assisted access toward the synthesis of 2-aryl/alkyl-3-(1<i>H</i>-benzo[<i>d</i>]imidazol-2-yl)-2, 3-dihydroquinazolin-4(1<i>H</i>)-ones

<p>An efficient, catalyst-free, microwave-assisted approach has been developed for the synthesis of 2-aryl/alkyl-3-(1<i>H</i>-benzo[<i>d</i>]imidazol-2-yl)-2,3-dihydroquinazolin-4(1<i>H</i>)-one derivatives by condensing 2-aminobenzamides with various aliphatic, aromatic, and heterocyclic aldehydes. This catalyst-free approach exhibited good functional group compatibility and produced the desired products in good to excellent yields in just 10–20 min. This approach can be seen as a better alternative of the metal-catalyzed protocols used for the synthesis of this class of compounds. The formation of desired compound has also been confirmed by X-ray analysis.</p