Nonequilibrium phase transitions and stationary state solutions of a three-dimensional random-field Ising model under a time dependent periodic external field

Nonequilibrium behavior and dynamic phase transition properties of a kinetic Ising model under the influence of periodically oscillating random-fields have been analyzed within the framework of effective field theory (EFT) based on a decoupling approximation (DA). Dynamic equation of motion has been solved for a simple cubic lattice ($q=6$) by utilizing a Glauber type stochastic process. Amplitude of the sinusoidally oscillating magnetic field is randomly distributed on the lattice sites according to bimodal and trimodal distribution functions. For a bimodal type of amplitude distribution, it is found in the high frequency regime that the dynamic phase diagrams of the system in temperature versus field amplitude plane resemble the corresponding phase diagrams of pure kinetic Ising model. Our numerical results indicate that for a bimodal distribution, both in the low and high frequency regimes, the dynamic phase diagrams always exhibit a coexistence region in which the stationary state (ferro or para) of the system is completely dependent on the initial conditions whereas for a trimodal distribution, coexistence region disappears depending on the values of system parameters.Comment: 11 pages, 11 figure

Effective field theory analysis of 3D random field Ising model on isometric lattices

Ising model with quenched random magnetic fields is examined for single Gaussian, bimodal and double Gaussian random field distributions by introducing an effective field approximation that takes into account the correlations between different spins that emerge when expanding the identities. Random field distribution shape dependencies of the phase diagrams and magnetization curves are investigated for simple cubic, body centered and face centered cubic lattices. The conditions for the occurrence of reentrant behavior and tricritical points on the system are also discussed in detail.Comment: 13 pages, 8 figure

TSHRV656F Activating Variant of the Thyroid Stimulating Hormone Receptor Gene in Neonatal Onset Hyperthyroidism: A Case Review

An activating variant of the thyroid stimulating hormone receptor (TSHR) gene is one of the rare causes of neonatal hyperthyroidism. This disorder may occur as a result of an autosomal dominant inheritance or sporadically through de novo variation. Here we present a case of neonatal onset congenital non-autoimmune hyperthyroidism (NAH) with a sporadic germline activating TSHRV656F variant. A female infant with tachycardia, who was transferred due to hyperthyroidism in the first week of life, displayed no other symptoms or signs. The patient’s mother did not have Graves’ disease, and TSHR stimulating antibodies were not present in the mother or baby. Imaging showed thyroid gland hyperplasia and left ventricular hypertrophy, the patient was subsequently put on methimazole treatment. After six months undergoing treatment, a heterozygous p.Val656Phe (V656F) (c.1966G>T) variant was detected on exon 10 of the TSHR gene. The variant was not identified in the mother and father, so the case was assumed to be sporadic. In conclusion, although the literature describes V656F variant as a somatic variant in children and adults with toxic thyroid nodule(s) that results in the structural activation of the TSH receptor, no previous cases of neonatal hyperthyroidism due to TSHRV656F variant have been reported. This study is the first case review that highlights the relationship between TSHRV656F variant and neonatal onset NAH

DIAGNOSIS AND TREATMENT OF DIABETIC FOOT ULCERS

Diyabetik ayak ülserleri diyabetin sık görülen ve ciddi bir kronik komplikasyonudur. Diyabetikayak ülserleri diyabetik hastalarda önemli bir morbidite ve mortalite nedenidir. Diyabetikayak ülserlerinin izlem ve tedavisi periferik arter hastalığı, nöropati, travma ve enfeksiyongibi ilişkili nedenler doğrultusunda bireyselleştirilmelidir. Cerrahi ve cerrahi dışı temel yarabakımı prensipleri bu yaraların etkin bir şekilde iyileşmesinde vazgeçilmez bir unsurdur.Ayak ülseri oluşumunun önlenmesi de tedavisi kadar önemlidir ve diyabetin bu ciddikomplikasyonuna karşı en ekonomik yaklaşımıdır. Bu yazıda diyabetik ayak ülserleri nedenlerive patofizyolojisi birlikte incelenmiş, klinik değerlendirme ve tedavi seçenekleri gözdengeçirilmiştir.Diabetic foot ulcers are common and serious chronic complications of diabetes. They are animportant cause of mortality and morbidity. The management of diabetic foot ulcers shouldbe individualized according to the causes of the ulcer such as peripheral arterial disease,neuropathy, pressure trauma, and infection. Basic principles of wound care, includingsurgical and nonsurgical components, are essential to effective healing of these wounds.Prevention of foot ulceration is also important, and the most cost-effective strategy formanaging this serious complication of diabetes. In this article, we performed a review ofdiabetic foot ulcers in terms of its causes, pathophysiology, clinical approach andmanagement

Turner syndrome and associated problems in turkish children: A multicenter study

Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosi) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto’s thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. © Journal of Clinical Research in Pediatric Endocrinology

Prevalence of common mental disorders among Syrian refugee children and adolescents in Sultanbeyli district, Istanbul: results of a population-based survey.

AIMS: Research demonstrates elevated levels of common mental disorders among Syrian refugees, but the majority of studies have, to date, focused on adult populations. This study aims to estimate the prevalence of depression, anxiety and post-traumatic stress disorder (PTSD) among Syrian children and adolescents living in Sultanbeyli district of Istanbul, Turkey. METHODS: A population-based survey among Syrian children and adolescents aged 8-17 years living in Sultanbeyli district was conducted in 2019, as part of an all-age survey of disability. 80 clusters of 50 participants (all-ages) were selected from the local municipality's refugee registration database using probability proportionate to size sampling. Children aged 8-17 years were assessed for symptoms of common mental disorders using the Child Revised Impact of Event Scale (CRIES-8) and abbreviated versions of the Center for Epidemiologic Studies Depression Scale for Children (CES-DC) and the Screen for Child Anxiety Related Disorders (SCARED). RESULTS: Of the 852 participants, 23.7% (95% CI 19.9-27.2) screened positive for symptomatic depression, PTSD and anxiety. The prevalence estimates for depression, PTSD and anxiety were 12.5% (95% CI 9.8-15.6), 11.5% (95% CI 9.1-14.4) and 9.2% (95% CI 6.8-12.1), respectively. Depression and PTSD were significantly more common in older adolescents, whilst anxiety and PTSD were significantly more common in girls. Depression was more common in children from poorer households and those who had received no education. Children coming from larger households were less likely to show symptoms of PTSD. CONCLUSIONS: Syrian refugee children and adolescents are vulnerable to common mental disorders, and culturally appropriate prevention and intervention support are needed for this population

Hasan Ali Yücel'in arkasından:Sen

Taha Toros Arşivi, Dosya No: 109-Hasan Ali-Can Yüce