Detecting the Effect of Umckaloabo/EPs®7630 Liquid Extract after its Therapeutic Purposed Usage in Calves Showing Symptoms of Respiratory Tract Infection

Background: Respiratory tract diseases are commonly seen in beef cattle. Young calves are affected with many respiratory pathogens. Viral pathogens are particularly seen. There are many causative factors, e.g. environmental conditions, immune system of calves. Therefore, alternative treatments are needed for viral respiratory infections. The purpose of the current study was to investigate effectiveness of Umckaloabo/EPs®7630 liquid extract in some bovine viral pathogens of young beef calves.Materials, Methods & Results: Antibody presence in terms of bovine herpesvirus type 1 (BHV-1), bovine viral diarrhea virus (BVDV), bovine parainfluenza virus type 3 (BPIV-3), bovine respiratory syncytial virus (BRSV) and bovine adenovirus type 3 (BAV-3) was searched in blood serum samples of 40 Holstein calves aged 6 months and over showing respiratory tract infection symptoms. All animals were found seronegative in terms of other factors except BRSV. Out of 20 BRSV seropositive calves, 10 of them were classified as control group and the other ten as testing group. BRSV antibody titers were also detected in blood samples of both groups on day 0. Umckaloabo/EPs®7630 liquid extract was given through oral route to animals in testing group according to their weights for 14 days morning, noon and night. No application was performed on animals in control group. BRSV antibody titers were detected in blood samples of animals in both groups taken on days 1st, 3rd, 5th, 7th, 10th and 14th. At the end of day 14th, BRSV antibody titer increased in 9 out of 10 animals (90%) in testing group that were given Umckaloabo/EPs® 7630 liquid extract while one of them (10%) showed no variability. BRSV antibody titer increased in 6 out of 10 animals (60%) in control group while it decreased in one of them (10%) and 3 of them (30%) showed no variability. In testing group, BRSV antibody titer started to increase on day 3rd in 6 out of 10 animals (60%), on day 5th in one (10%), on day 10th in one (10%) and on day 14th in another (10%). In control group, BRSV antibody titer started to increase on day 3rd in 3 out of 10 animals (30%) and on day 5th in 3 of them (30%). When haematologic values of blood samples taken from animals in testing and control groups on day 14th were studied comparatively, no statistical importance (P < 0.01 or P < 0.05) and difference was detected. As a result, in stock calves showing respiratory tract infection symptoms, applying Umckaloabo/EPs® 7630 liquid extract helped BRSV antibody titer to increase and symptoms decreased. The increase in antibody titers started from day 3rd especially after applying Umckaloabo/EPs® 7630 liquid extract.Discussion: Respiratory system infections are contagious and fatal in calves. Respiratory tract bacterial and viral vaccinations are applied in order to prevent losses of calves due to these problems. However, these vaccinations are not sufficient most of the time and antibiotics+supportive treatment applications follow afterwards. Therefore, we advise to use a herbal product, Umckaloabo/ EPs®7630 liquid extract, that has both an antiviral efficiency and a feature of supporting immune system in order to prevent mortalities in stock calves, to stop the infection from spreading on all the herd and to decrease the symptoms of respiratory system. We believe that the obtained data should be supported with more examples and more wide-ranging studies

Evaluation of hearing and cochlear function by audiometric testing in patients with hyperemesis gravidarum

INTRODUCTION: The aim of this study was to investigate cochlear functions in patients with hyperemesis gravidarum (HG).METHODS: Twenty-nine HG patients (58 ears) and 31 healthy control subjects (62 ears) were included. Audiometry testings at 250 and 500 Hz and 1, 2, 4, 8, 10, 12, 14, 16 kHz were performed to the patients and controls.RESULTS: Mean age of patients with HG was 26,5 ± 4,4 years and the mean age of control group was 28,0 ± 4,2 years. At the time of the tests mean gestational age of the HG group and controls were 9 and 11 weeks respectively. No differences were observed between the groups in tympanic membrane status, or other otolaringological evaluations. No significant differences were observed in audiometric tests at any frequencies between the groups (p values for all > 0.05).CONCLUSION: There was not a difference between pregnant cases with HG and cases with normal pregnancy in terms of audimetric tests. Cochlear functions are not affected remarkably in women with HG

Absorptive capacity and firm performance: the mediating role of strategic agility

The purpose of the study was to examine the mediating role of strategic agility in absorptive capacity’s effects on the firm performance of accommodation establishments in Turkey. A survey was used to collect data. Questionnaires were conveyed via e-mail and 190 applicable questionnaires were gathered. From the exploratory factor analyses, absorptive capacity was determined to have two dimensions (acquisition and use). While the acquisition dimension was revealed not to have a direct effect on firm performance, the use dimension was found to have a direct effect on firm performance. The acquisition and use dimensions have a positive effect on strategic agility and strategic agility positively affects firm performance. In addition, it was revealed that the acquisition and use dimensions have an indirect effect on firm performance through strategic agility

Absorptive capacity: an empirical study on Turkey’s hotel companies

This article was presented at the 1st International Congress on Tourism, Economic and Business Sciences (01-05 November 2017- Skopje).Absorptive capacity plays a key role in determining a firm’s capability to access and make use of external knowledge. It also refers to the ability to locate new ideas and to incorporate them into an organization’s processes, and this is widely seen as a major contributor to organizational performance. It includes organizational routines and strategic processes by which a firm acquires, assimilates, transforms, and exploits knowledge. In this study, absorptive capacity was examined in terms of hotel operations in Turkey. The study aimed at uncovering the effects of the dimensions of absorptive capacity (acquire, assimilate, transform, exploit) on firm performance and determining if there was a difference in the dimensions of absorptive capacity according to the hotel’s star and hotel age. Data were collected using a questionnaire and 124 applicable questionnaires were gathered at the end of the study. According to results of regression analysis, it was found that the dimensions of acquire, assimilate and adoption of absorptive capacity had a significant effect on firm performance. In contrast to expectations, no significant effect of the transform dimension of absorptive on firm performance was determined. Anova analysis was used to determine whether if there was a difference in the dimensions of absorptive capacity according to the hotel’s star and hotel age. According to the analysis results, no difference was detected.Özümseme kapasitesi, bir işletmenin dış bilgiye erişme ve bunlardan yararlanma yeteneklerini belirlemede önemli bir rol oynamaktadır. Aynı zamanda, yeni fikirleri bulma ve bunları bir organizasyonun süreçlerine dâhil etme kabiliyetine işaret etmekte ve örgütsel performansa büyük katkı sağlayıcı olarak görülmektedir. Bir firmanın dışsal bilgiyi edinmesi, benimsemesi, dönüştürmesi ve kullanması için örgütsel rutinleri ve stratejik süreçleri içermektedir. Bu çalışmada özümseme kapasitesi, Türkiye otel işletmeciliği açısından incelenmiştir. Çalışma, özümseme kapasitesinin boyutlarının (edinme, benimseme, dönüştürme ve kullanma) firma performansı üzerindeki etkilerinin ortaya çıkarılmasını ve otelin yıldızı ve yaşına göre özümseme kapasite boyutlarında bir farklılık olup olmadığını saptamayı amaçlamaktadır. Veriler, anket tekniği kullanılarak toplanmış ve çalışma sonunda 124 kullanılabilir anket formu elde edilmiştir. Regresyon analizinin sonuçlarına göre, özümseme kapasitesinin edinme, benimseme ve kullanma boyutlarının, firma performansı üzerinde belirgin bir etkisi olduğu bulunmuştur. Beklen-tilerin aksine, özümseme kapasitesinin dönüşüm boyutunun firma performansı üzerinde önemli bir etkisi tespit edilememiştir. Otelin yıldız ve otel yaşına göre özümseme kapasitenin boyutlarında bir farklılık olup olmadığının belirlenmesi için Anova analizi kullanılmıştır. Analiz sonuçlarına göre, özümseme kapasitesi boyutlarında hiçbir fark tespit edilmemiştir

Transient osteoporosis of the hip associated with pregnancy: case report

Transient osteoporosis of the hip associated with pregnancy is a clinical condition with an unclear etiology seen in pregnant women in the 3rd trimester that may lead to severe pain and disability. In this article we present a case getting transient osteoporosis associated with pregnancy based on clinical and radiological findings and discussed it under the guidance of the literature

Examinations of bracket and archwire types on treatment duration of mandibular anterior irregularity

Amaç: Çalışmamızın amacı hızlı seviyeleme iddiaları olan Speed braket ve Supercable ark telinin mandibular kesici dişlerin seviyelenmesi için geçen sürede etkilerinin konvansiyonel braket ve ark telleriyle karşılaştırmalı olarak incelenmesidir. Materyal-Metot: Çalışmamıza Sınıf I anterior hafif veya orta seviye çapraşıklığa sahip 65 birey dahil edilmiştir. Hastalar dört grupta değerlendirilerek 16 hastadan oluşan (8 kız, 8 erkek) birinci gruba Speed System braket ve Supercable ark teli, 15 hastadan oluşan (11 kız, 4 erkek) ikinci gruba Speed System braket ve NiTi ark teli, 15 hastadan oluşan (12 kız, 3 erkek) üçüncü gruba Obey I braket ve Supercable ark teli, 19 hastadan oluşan (15 kız, 4 erkek) dördüncü gruba Obey I braket ve NiTi ark teli uygulanmıştır. Hastaların tedavi öncesi ve tedavi sırasındaki değerleri ağız içi tarama yapılarak dijital olarak alınmıştır. İki ay boyunca ilk olarak 0,016" ve daha sonra iki ay boyunca 0,018" Supercable ve NiTi ark telleri uygulandıktan sonra Little çapraşılık indeksine göre hesaplanan mandibular çapraşıklığı çözme etkinlikleri ölçülmüştür. Bulgular: Tüm gruplarda çapraşıklık indekslerinde istatistiksel olarak anlamlı düşüşler tespit edilmiştir (p<0,001). Gruplar arası ise konvansiyonel braket ve ark teli gruplarında diğer gruplara göre istatistiksel olarak anlamlı daha fazla düşüş bulunmuştur (p<0,001). Sonuç: Speed system braket ve Supercable ark teli grupları, konvansiyonel braket ve ark teli gruplarıyla karşılaştırıldığında tedavi etkinliği daha az bulunmuştur.Objective: The aim of our study is to examine the effects of Speed bracket and Supercable on the level of mandibular incisor teeth compared with conventional brackets and archwires. Material-Method: Our study was conducted on 65 subjects with skeletal and dental Class I mild or moderate anterior crowding. Patients were evaluated in four groups, the first group consisted of 16 patients (8 girls, 8 males), Speed System bracket and Supercable archwire, second group 15 patients (11 girls, 4 boys) Speed System bracket and NiTi archwire, third group 15 patients (13 girls, 2 males) Obey I bracket and Supercable archwire, fourth group 19 patients (15 girls, 4 males) Obey I bracket and Niti archwire. Pretreatment and treatment values of the patients were taken digitally by intraoral scanning.Supercable and NiTi archwires were applied for the first two months at 0.016" and then for two months at 0.018". After the four-month treatment period, groups were assessed for the effects of mandibular anterior crowding according to the Little Index. Results: Statistically significant decreases on irregularity index have been found in all groups. (p<0.001). There was a statistically significant decrease in the conventional bracket and arc wire groups compared to the other groups (p<0.001). Conclusions: Speed system brackets and Supercable arctreated groups were found to be less effective when compared to conventional groups.No sponso

Evaluation of hearing and cochlear function by audiometric testing in patients with hyperemesis gravidarum

INTRODUCTION: The aim of this study was to investigate cochlear functions in patients with hyperemesis gravidarum (HG).METHODS: Twenty-nine HG patients (58 ears) and 31 healthy control subjects (62 ears) were included. Audiometry testings at 250 and 500 Hz and 1, 2, 4, 8, 10, 12, 14, 16 kHz were performed to the patients and controls.RESULTS: Mean age of patients with HG was 26,5 ± 4,4 years and the mean age of control group was 28,0 ± 4,2 years. At the time of the tests mean gestational age of the HG group and controls were 9 and 11 weeks respectively. No differences were observed between the groups in tympanic membrane status, or other otolaringological evaluations. No significant differences were observed in audiometric tests at any frequencies between the groups (p values for all > 0.05).CONCLUSION: There was not a difference between pregnant cases with HG and cases with normal pregnancy in terms of audimetric tests. Cochlear functions are not affected remarkably in women with HG

The Effects of Leukocyte- and Platelet-Rich Plasma (L-Prp) and Pure Platelet-Rich Plasma (P-Prp) in a Rat Endometriosis Model

Objective: We aimed to investigate the effect of platelet‑rich plasma (PRP) derivatives, which can be produced from the patient’s blood and have minimal side effects, on endometriosis.Methods: To our knowledge, this is the first study in the literature that studies the relationship between PRP and endometriosis. Endometriosis foci were created in the first operation. In the second operation (30th day), four groups were formed wherein group 1 (n = 8) was administered saline, group 2 (n = 7) leukocyte and platelet‑rich plasma (L‑PRP), group 3 (n = 8) pure platelet‑rich plasma (P‑PRP) and group 4 (n = 10) was used to obtain PRP. In the last operation (60th day), the endometriotic foci was measured and then excised.Findings: There was no statistically significant difference between the pre and post volumes of the endometriotic foci, between their volume differences, and volume difference rates (P &gt; 0.05). However, it was observed that existing implant volumes in all groups decreased statistically significantly within their groups by the end of the experiment compared to the previous volumes (P &lt; 0.05).Conclusion: When the implants were assessed through histopathological scoring in terms of edema, vascular congestion, inflammatory cell&nbsp; infiltration, hemorrhage, epithelial line, and hemosiderin accumulation, and immunohistochemical staining was assessed in terms of VEGF, there was no significant difference in the comparison between the groups. Although L‑PRP and P‑PRP generated more reduction in the endometriosis foci, they did not create any statistical differences. Key words: L‑Prp; P‑Prp; VEGF; endometriosis

Impact of opioid-free analgesia on pain severity and patient satisfaction after discharge from surgery: multispecialty, prospective cohort study in 25 countries

Background: Balancing opioid stewardship and the need for adequate analgesia following discharge after surgery is challenging. This study aimed to compare the outcomes for patients discharged with opioid versus opioid-free analgesia after common surgical procedures.Methods: This international, multicentre, prospective cohort study collected data from patients undergoing common acute and elective general surgical, urological, gynaecological, and orthopaedic procedures. The primary outcomes were patient-reported time in severe pain measured on a numerical analogue scale from 0 to 100% and patient-reported satisfaction with pain relief during the first week following discharge. Data were collected by in-hospital chart review and patient telephone interview 1 week after discharge.Results: The study recruited 4273 patients from 144 centres in 25 countries; 1311 patients (30.7%) were prescribed opioid analgesia at discharge. Patients reported being in severe pain for 10 (i.q.r. 1-30)% of the first week after discharge and rated satisfaction with analgesia as 90 (i.q.r. 80-100) of 100. After adjustment for confounders, opioid analgesia on discharge was independently associated with increased pain severity (risk ratio 1.52, 95% c.i. 1.31 to 1.76; P &lt; 0.001) and re-presentation to healthcare providers owing to side-effects of medication (OR 2.38, 95% c.i. 1.36 to 4.17; P = 0.004), but not with satisfaction with analgesia (beta coefficient 0.92, 95% c.i. -1.52 to 3.36; P = 0.468) compared with opioid-free analgesia. Although opioid prescribing varied greatly between high-income and low- and middle-income countries, patient-reported outcomes did not.Conclusion: Opioid analgesia prescription on surgical discharge is associated with a higher risk of re-presentation owing to side-effects of medication and increased patient-reported pain, but not with changes in patient-reported satisfaction. Opioid-free discharge analgesia should be adopted routinely