Predicción de la mortalidad en pacientes con hemorragia subaracnoidea mediante el uso de un algoritmo de inteligencia artificial basado en redes neuronales y en el TC inicial

La hemorragia subaracnoidea (HSA) conlleva altas tasas de morbimortalidad. Se han identificado varios factores de riesgo como estimadores de mortalidad y resultados funcionales; sin embargo, las predicciones son imprecisas y, en ocasiones, difíciles de establecer de forma precoz. Los algoritmos de inteligencia artificial (IA) permiten manejar datos complejos y de gran dimensión. Dentro de la IA, las redes neuronales (NN), una técnica de aprendizaje automatizado que es capaz de generar predicciones muy precisas a partir de datos de imágenes. El objetivo de este trabajo es predecir la mortalidad en una cohorte consecutiva de pacientes con HSA mediante el procesamiento de la tomografía computarizada inicial en un algoritmo basado en redes neuronales. Se ha realizado un estudio multicéntrico de una cohorte retrospectiva consecutiva de pacientes con HSA entre 2011 y 2022. Se analizaron variables demográficas, clínicas y radiológicas. Las imágenes de tomografía computarizada iniciales se preprocesaron y se usaron como entrada para entrenar una NN cuya arquitectura se basa en DenseNet-121. La variable resultado fue la mortalidad en los tres primeros meses. Las cohortes de entrenamiento, validación y test se obtuvieron mediante una división aleatoria del conjunto de datos inicial. Se procesaron imágenes de 219 pacientes, 175 para entrenamiento y validación de la NN y 44 para su evaluación. El 52,5% de los pacientes eran mujeres y la mediana de edad fue de 57,9 años. El 18,5% fueron HSA idiopáticas. La mediana de WFNS al ingreso fue de 2 y la mortalidad fue del 28,5%. El modelo mostró un gran rendimiento en la predicción de muerte en pacientes con HSA utilizando exclusivamente las imágenes de la tomografía computarizada inicial (Accuracy = 74%, F1 = 72% y AUC = 82%). La conclusión a la que se llegó es que las modernas técnicas de procesamiento de imágenes basadas en inteligencia artificial y redes neuronales hacen posible predecir la mortalidad en pacientes con HSA con alta precisión utilizando imágenes de TC como única entrada. Estos modelos pueden optimizarse al incluir más datos y pacientes, lo que resulta en una mejor capacitación, desarrollo y rendimie.Grado en Medicin

International trade and gender equality : an applied approach

RESUMEN: Las situaciones de libre comercio y desigualdad de género y las políticas necesarias para superarlas han sido percibidas por la Unión Europea como una de las prioridades a las que se debe hacer frente de modo más activo. A lo largo del presente trabajo se investiga en el entorno europeo el posible efecto de la actividad exterior sobre la desigualdad de género, específicamente sobre la brecha salarial. Resalta la correlación negativa entre ambas variables, consiguiendo unos resultados más significativos cuando se restringe la muestra para los catorce países con mayor coeficiente de apertura. En este contexto el comercio internacional contribuye a favorecer a las mujeres, pero siendo necesarios los principios de la Unión Europea por tratar de consolidar la plena igualdad entre ambos sexos. ABSTRACT: Situations of free trade and gender inequality and politics necessary to overcome them have been perceived by the European Union as one of the priorities that must confront a more active way. Throughout this work, I investigate in the European Union the possible effect that the free trade about gender inequality, specifically on the wage gap. The correlation is negative between two indicators, and results are more significant when the sample is restricted for the fourteen countries with the highest openness coefficient. In this context, the international trade contributes to favoring to women, but principles of the European Union are necessary to try to consolidate full equality between both genders.Grado en Economí

Estudio de la microestructura y propiedades mecánicas de cerámicas eutécticas procesadas por horno láser

En este proyecto se presentan los resultados y conclusiones obtenidos tras tratar por fusión zonal con horno láser muestras de las siguientes mezclas de óxidos cerámicos en proporciones estequiométricas: MnO-Al2O3, CoO-Al2O3 y CaO-Al2O3, a distintas condiciones de tratamiento, para posteriormente realizar un estudio en profundidad de su microestructura mediante: microscopio electrónico de barrido (SEM), caracterización composicional mediante microscopio electrónico (EDX), Análisis Rayos X (XRD).Y por último, caracterizar mecánicamente dichas muestras mediante un ensayo de nanodureza

Neurological outcome prediction in patients with subarachnoid hemorrhage using a model based on initial CT scan, clinical data and neural networks [Abstract]

Oral e-Poster Presentations - Booth 1: Vascular A (Aneurysms), September 25, 2023, 1:00 PM - 2:30 PM Background: Subarachnoid hemorrhage(SAH) entails high morbidity and mortality. Several risk factors have been identified as mortality and functional outcome estimators. Artificial intelligence(AI) enables handling high-dimensional and complex data. Neural networks (NN), an automated machine learning technique, can be trained with images and/or data to perform accurate predictions. This study aims to predict the functional outcome of SAH patients at three months using a NN-based algorithm that processes initial CT scan images and clinical features. Methods: Clinical features and CT scans of a multicentric retrospective cohort of SAH patients were analyzed. AUCMEDI, an open-source Python library, was used to create and train two different NNs: one based solely on images and the other incorporating clinical features (age and WFNS). The output variable was a dichotomized modified Rankin scale at 3 months(mRS): Good Outcome=mRS<4; Bad Outcome= mRS<4. The initial dataset was randomly split into training, validation, and test cohorts at a ratio of 70%-10%-20%. Results: Images and data from 219 patients were processed. 52.5% were female patients with a mean age of 57. 18.3% were idiopathic SAH. Median WFNS on admission was 2, and mortality was 28.8%. 54.3% of patients presented a good outcome at 3 months follow-up. Predicting neurological outcome, the model exclusively based on CT scan images (Accuracy=86%, F1=86% and AUC=0.89) outperformed the one based on images and clinical data (Accuracy=79%, F1=78% and AUC=0.87). Explainable Artificial Intelligence maps were built to highlight the areas the algorithm accounts on the CT scan in order to classify patients. Conclusions: Modern image processing techniques based on AI and NN make possible to predict neurological outcome in SAH patients with high accuracy using CT scan images as the only input. Models might be optimized by including more data and patients, therefore improving their performance on tasks beyond the skills of conventional clinical knowledge

Intramuscular EMG-driven Musculoskeletal Modelling: Towards Implanted Muscle Interfacing in Spinal Cord Injury Patients

Objective: Surface EMG-driven modelling has been proposed as a means to control assistive devices by estimating joint torques. Implanted EMG sensors have several advantages over wearable sensors but provide a more localized information on muscle activity, which may impact torque estimates. Here, we tested and compared the use of surface and intramuscular EMG measurements for the estimation of required assistive joint torques using EMG driven modelling. Methods: Four healthy subjects and three incomplete spinal cord injury (SCI) patients performed walking trials at varying speeds. Motion capture marker trajectories, surface and intramuscular EMG, and ground reaction forces were measured concurrently. Subject-specific musculoskeletal models were developed for all subjects, and inverse dynamics analysis was performed for all individual trials. EMG-driven modelling based joint torque estimates were obtained from surface and intramuscular EMG. Results: The correlation between the experimental and predicted joint torques was similar when using intramuscular or surface EMG as input to the EMG-driven modelling estimator in both healthy individuals and patients. Conclusion: We have provided the first comparison of non-invasive and implanted EMG sensors as input signals for torque estimates in healthy individuals and SCI patients. Significance: Implanted EMG sensors have the potential to be used as a reliable input for assistive exoskeleton joint torque actuation

Polarized blazar X-rays imply particle acceleration in shocks

Full list of authors: Liodakis, Ioannis; Marscher, Alan P.; Agudo, Ivan; Berdyugin, Andrei V.; Bernardos, Maria I.; Bonnoli, Giacomo; Borman, George A.; Casadio, Carolina; Casanova, Victor; Cavazzuti, Elisabetta; Cavero, Nicole Rodriguez; Di Gesu, Laura; Di Lalla, Niccolo; Donnarumma, Immacolata; Ehlert, Steven R.; Errando, Manel; Escudero, Juan; Garcia-Comas, Maya; Agis-Gonzalez, Beatriz; Husillos, Cesar; Jormanainen, Jenni; Jorstad, Svetlana G.; Kagitani, Masato; Kopatskaya, Evgenia N.; Kravtsov, Vadim; Krawczynski, Henric; Lindfors, Elina; Larionova, Elena G.; Madejski, Grzegorz M.; Marin, Frederic; Marchini, Alessandro; Marshall, Herman L.; Morozova, Daria A.; Massaro, Francesco; Masiero, Joseph R.; Mawet, Dimitri; Middei, Riccardo; Millar-Blanchaer, Maxwell A.; Myserlis, Ioannis; Negro, Michela; Nilsson, Kari; O'Dell, Stephen L.; Omodei, Nicola; Pacciani, Luigi; Paggi, Alessandro; Panopoulou, Georgia V.; Peirson, Abel L.; Perri, Matteo; Petrucci, Pierre-Olivier; Poutanen, Juri; Puccetti, Simonetta; Romani, Roger W.; Sakanoi, Takeshi; Savchenko, Sergey S.; Sota, Alfredo; Tavecchio, Fabrizio; Tinyanont, Samaporn; Vasilyev, Andrey A.; Weaver, Zachary R.; Zhovtan, Alexey V.; Antonelli, Lucio A.; Bachetti, Matteo; Baldini, Luca; Baumgartner, Wayne H.; Bellazzini, Ronaldo; Bianchi, Stefano; Bongiorno, Stephen D.; Bonino, Raffaella; Brez, Alessandro; Bucciantini, Niccolo; Capitanio, Fiamma; Castellano, Simone; Ciprini, Stefano; Costa, Enrico; De Rosa, Alessandra; Del Monte, Ettore; Di Marco, Alessandro; Doroshenko, Victor; Dovciak, Michal; Enoto, Teruaki; Evangelista, Yuri; Fabiani, Sergio; Ferrazzoli, Riccardo; Garcia, Javier A.; Gunji, Shuichi; Hayashida, Kiyoshi; Heyl, Jeremy; Iwakiri, Wataru; Karas, Vladimir; Kitaguchi, Takao; Kolodziejczak, Jeffery J.; La Monaca, Fabio; Latronico, Luca; Maldera, Simone; Manfreda, Alberto; Marinucci, Andrea; Matt, Giorgio; Mitsuishi, Ikuyuki; Mizuno, Tsunefumi; Muleri, Fabio; Ng, Stephen C. -Y.; Oppedisano, Chiara; Papitto, Alessandro; Pavlov, George G.; Pesce-Rollins, Melissa; Pilia, Maura; Possenti, Andrea; Ramsey, Brian D.; Rankin, John; Ratheesh, Ajay; Sgro, Carmelo; Slane, Patrick; Soffitta, Paolo; Spandre, Gloria; Tamagawa, Toru; Taverna, Roberto; Tawara, Yuzuru; Tennant, Allyn F.; Thomas, Nicolas E.; Tombesi, Francesco; Trois, Alessio; Tsygankov, Sergey; Turolla, Roberto; Vink, Jacco; Weisskopf, Martin C.; Wu, Kinwah; Xie, Fei; Zane, Silvia.--This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Most of the light from blazars, active galactic nuclei with jets of magnetized plasma that point nearly along the line of sight, is produced by high-energy particles, up to around 1 TeV. Although the jets are known to be ultimately powered by a supermassive black hole, how the particles are accelerated to such high energies has been an unanswered question. The process must be related to the magnetic field, which can be probed by observations of the polarization of light from the jets. Measurements of the radio to optical polarization—the only range available until now—probe extended regions of the jet containing particles that left the acceleration site days to years earlier1,2,3, and hence do not directly explore the acceleration mechanism, as could X-ray measurements. Here we report the detection of X-ray polarization from the blazar Markarian 501 (Mrk 501). We measure an X-ray linear polarization degree ΠX of around 10%, which is a factor of around 2 higher than the value at optical wavelengths, with a polarization angle parallel to the radio jet. This points to a shock front as the source of particle acceleration and also implies that the plasma becomes increasingly turbulent with distance from the shock. © The Author(s) 2022.I.L. was supported by the JSPS postdoctoral short-term fellowship programme. The Imaging X-ray Polarimetry Explorer (IXPE) is a joint US and Italian mission. The US contribution is supported by the National Aeronautics and Space Administration (NASA) and led and managed by its Marshall Space Flight Center (MSFC), with industry partner Ball Aerospace (contract NNM15AA18C). The Italian contribution is supported by the Italian Space Agency (Agenzia Spaziale Italiana, ASI) through contract ASI-OHBI-2017-12-I.0, agreements ASI-INAF-2017-12-H0 and ASI-INFN-2017.13-H0, and its Space Science Data Center (SSDC) with agreements ASI-INAF-2022-14-HH.0 and ASI-INFN 2021-43-HH.0, and by the Istituto Nazionale di Astrofisica (INAF) and the Istituto Nazionale di Fisica Nucleare (INFN) in Italy. This research used data products provided by the IXPE Team (MSFC, SSDC, INAF and INFN) and distributed with additional software tools by the High-Energy Astrophysics Science Archive Research Center (HEASARC), at NASA Goddard Space Flight Center (GSFC). Data from the Steward Observatory spectropolarimetric monitoring project were used. This programme is supported by Fermi Guest Investigator grants NNX08AW56G, NNX09AU10G, NNX12AO93G and NNX15AU81G. This research has made use of data from the RoboPol programme, a collaboration between Caltech, the University of Crete, the Institute of Astrophysics-Foundation for Research and Technology (IA-FORTH), the Inter-University Centre for Astronomy and Astrophysics (IUCAA), the Max Planck Institute for Radioastronomy (MPIfR) and the Nicolaus Copernicus University, which was conducted at Skinakas Observatory in Crete, Greece. The Instituto Astrofísica Andalucía (IAA)-Consejo Superior de Investigaciones Científicas (CSIC) co-authors acknowledge financial support from the Spanish Ministerio de Ciencia e Innovacion (MCINN) through the ‘Center of Excellence Severo Ochoa‘ award for the Instituto de Astrofisica de Andalucia-CSIC (SEV-2017-0709). Acquisition and reduction of the POLAMI and Monitoring AGN with Polarimetry at the Calar Alto Telescopes (MAPCAT) data were supported in part by Ministerio de Ciencia e Innovación (MICINN) through grants AYA2016-80889-P and PID2019-107847RB-C44. The POLAMI observations were carried out at the IRAM 30 m Telescope. IRAM is supported by the National Institute of Sciences of the Universe (INSU)/Scientific Research National Center (CNRS) (France), Max-Planck-Gesellschaft (MPG) (Germany) and Instituto Geográfico Nacional (IGN) (Spain). The research at Boston University was supported in part by National Science Foundation grant AST-2108622, NASA Fermi Guest Investigator grant 80NSSC21K1917 and NASA Swift Guest Investigator grant 80NSSC22K0537. This study uses observations conducted with the 1.8 m Perkins Telescope Observatory in Arizona (USA), which is owned and operated by Boston University. Based on observations obtained at the Hale Telescope, Palomar Observatory as part of a continuing collaboration between the California Institute of Technology, NASA/Jet Propulsion Laboratory (JPL), Yale University and the National Astronomical Observatories of China. This research made use of Photutils, an Astropy package for detection and photometry of astronomical sources60. G.V.P. acknowledges support by NASA through the NASA Hubble Fellowship grant no. HST-HF2-51444.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Incorporated, under NASA contract NAS5-26555. Based on observations made with the Nordic Optical Telescope, owned in collaboration by the University of Turku and Aarhus University, and operated jointly by Aarhus University, the University of Turku and the University of Oslo, representing Denmark, Finland and Norway, the University of Iceland and Stockholm University at the Observatorio del Roque de los Muchachos, La Palma, Spain, of the Instituto de Astrofisica de Canarias. The data presented here were obtained (in part) with ALFOSC, which is provided by the Instituto de Astrofisica de Andalucia (IAA) under a joint agreement with the University of Copenhagen and the Nordic Optical Telescope. V.K. thanks the Vilho, Yrjö and Kalle Väisälä Foundation. J.J. was supported by Academy of Finland project 320085. E.L. was supported by Academy of Finland projects 317636 and 320045. Part of the French contribution was supported by the CNRS and the French spatial agency (CNES). Based on observations collected at the Observatorio de Sierra Nevada, owned and operated by the Instituto de Astrofisica de Andalucia (IAA-CSIC). Based on observations collected at the Centro Astronomico Hispano-Aleman (CAHA), proposal 22A-2.2-015, operated jointly by Junta de Andalucia and Consejo Superior de Investigaciones Cientificas (IAA-CSIC).Peer reviewe

X-Ray Polarization Observations of BL Lacertae

Full list of authors: Middei, Riccardo; Liodakis, Ioannis; Perri, Matteo; Puccetti, Simonetta; Cavazzuti, Elisabetta; Di Gesu, Laura; Ehlert, Steven R.; Madejski, Grzegorz; Marscher, Alan P.; Marshall, Herman L.; Muleri, Fabio; Negro, Michela; Jorstad, Svetlana G.; Agis-Gonzalez, Beatriz; Agudo, Ivan; Bonnoli, Giacomo; Bernardos, Maria, I; Casanova, Victor; Garcia-Comas, Maya; Husillos, Cesar; Marchini, Alessandro; Sota, Alfredo; Kouch, Pouya M.; Lindfors, Elina; Borman, George A.; Kopatskaya, Evgenia N.; Larionova, Elena G.; Morozova, Daria A.; Savchenko, Sergey S.; Vasilyev, Andrey A.; Zhovtan, Alexey, V; Casadio, Carolina; Escudero, Juan; Myserlis, Ioannis; Hales, Antonio; Kameno, Seiji; Kneissl, Ruediger; Messias, Hugo; Nagai, Hiroshi; Blinov, Dmitry; Bourbah, Ioakeim G.; Kiehlmann, Sebastian; Kontopodis, Evangelos; Mandarakas, Nikos; Romanopoulos, Stylianos; Skalidis, Raphael; Vervelaki, Anna; Masiero, Joseph R.; Mawet, Dimitri; Millar-Blanchaer, Maxwell A.; Panopoulou, Georgia, V; Tinyanont, Samaporn; Berdyugin, Andrei, V; Kagitani, Masato; Kravtsov, Vadim; Sakanoi, Takeshi; Imazawa, Ryo; Sasada, Mahito; Fukazawa, Yasushi; Kawabata, Koji S.; Uemura, Makoto; Mizuno, Tsunefumi; Nakaoka, Tatsuya; Akitaya, Hiroshi; Gurwell, Mark; Rao, Ramprasad; Di Lalla, Niccolo; Cibrario, Nicolo; Donnarumma, Immacolata; Kim, Dawoon E.; Omodei, Nicola; Pacciani, Luigi; Poutanen, Juri; Tavecchio, Fabrizio; Antonelli, Lucio A.; Bachetti, Matteo; Baldini, Luca; Baumgartner, Wayne H.; Bellazzini, Ronaldo; Bianchi, Stefano; Bongiorno, Stephen D.; Bonino, Raffaella; Brez, Alessandro; Bucciantini, Niccolo; Capitanio, Fiamma; Castellano, Simone; Ciprini, Stefano; Costa, Enrico; De Rosa, Alessandra; Del Monte, Ettore; Di Marco, Alessandro; Doroshenko, Victor; Dovciak, Michal; Enoto, Teruaki; Evangelista, Yuri; Fabiani, Sergio; Ferrazzoli, Riccardo; Garcia, Javier A.; Gunji, Shuichi; Hayashida, Kiyoshi; Heyl, Jeremy; Iwakiri, Wataru; Karas, Vladimir; Kitaguchi, Takao; Kolodziejczak, Jeffery J.; Krawczynski, Henric; La Monaca, Fabio; Latronico, Luca; Maldera, Simone; Manfreda, Alberto; Marin, Frederic; Marinucci, Andrea; Massaro, Francesco; Matt, Giorgio; Mitsuishi, Ikuyuki; Ng, C-Y; O'Dell, Stephen L.; Oppedisano, Chiara; Papitto, Alessandro; Pavlov, George G.; Peirson, Abel L.; Pesce-Rollins, Melissa; Petrucci, Pierre-Olivier; Pilia, Maura; Possenti, Andrea; Ramsey, Brian D.; Rankin, John; Ratheesh, Ajay; Romani, Roger W.; Sgro, Carmelo; Slane, Patrick; Soffitta, Paolo; Spandre, Gloria; Tamagawa, Toru; Taverna, Roberto; Tawara, Yuzuru; Tennant, Allyn F.; Thomas, Nicholas E.; Tombesi, Francesco; Trois, Alessio; Tsygankov, Sergey; Turolla, Roberto; Vink, Jacco; Weisskopf, Martin C.; Wu, Kinwah; Xie, Fei; Zane, Silvia.--This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.Blazars are a class of jet-dominated active galactic nuclei with a typical double-humped spectral energy distribution. It is of common consensus that the synchrotron emission is responsible for the low frequency peak, while the origin of the high frequency hump is still debated. The analysis of X-rays and their polarization can provide a valuable tool to understand the physical mechanisms responsible for the origin of high-energy emission of blazars. We report the first observations of BL Lacertae (BL Lac) performed with the Imaging X-ray Polarimetry Explorer, from which an upper limit to the polarization degree ΠX < 12.6% was found in the 2–8 keV band. We contemporaneously measured the polarization in radio, infrared, and optical wavelengths. Our multiwavelength polarization analysis disfavors a significant contribution of proton-synchrotron radiation to the X-ray emission at these epochs. Instead, it supports a leptonic origin for the X-ray emission in BL Lac. © 2022. The Author(s). Published by the American Astronomical Society.The Imaging X-ray Polarimetry Explorer (IXPE) is a joint US and Italian mission. The US contribution is supported by the National Aeronautics and Space Administration (NASA) and led and managed by its Marshall Space Flight Center (MSFC), with industry partner Ball Aerospace (contract NNM15AA18C). The Italian contribution is supported by the Italian Space Agency (Agenzia Spaziale Italiana, ASI) through contract ASI-OHBI-2017-12-I.0, agreements ASI-INAF-2017-12-H0 and ASI-INFN-2017.13-H0, and its Space Science Data Center (SSDC), and by the Istituto Nazionale di Astrofisica (INAF) and the Istituto Nazionale di Fisica Nucleare (INFN) in Italy. This research used data products provided by the IXPE Team (MSFC, SSDC, INAF, and INFN) and distributed with additional software tools by the High-Energy Astrophysics Science Archive Research Center (HEASARC), at NASA Goddard Space Flight Center (GSFC). We acknowledge financial support from ASI-INAF agreement n. 2022-14-HH.0. The research at Boston University was supported in part by National Science Foundation grant AST-2108622 and NASA Swift Guest Investigator grant 80NSSC22K0537. This research has made use of data from the RoboPol program, a collaboration between Caltech, the University of Crete, IA-FORTH, IUCAA, the MPIfR, and the Nicolaus Copernicus University, which was conducted at Skinakas Observatory in Crete, Greece. The IAA-CSIC coauthors acknowledge financial support from the Spanish "Ministerio de Ciencia e Innovacion" (MCINN) through the "Center of Excellence Severo Ochoa" award for the Instituto de Astrofísica de Andalucía-CSIC (SEV-2017-0709). Acquisition and reduction of the POLAMI, TOP-MAPCAR, and OSN data was supported in part by MICINN through grants AYA2016-80889-P and PID2019-107847RB-C44. The POLAMI observations were carried out at the IRAM 30 m Telescope. IRAM is supported by INSU/CNRS (France), MPG (Germany), and IGN (Spain). This Letter makes use of the following ALMA director's discretionary time data under proposal ESO#2021.A.00016.T. ALMA is a partnership of ESO (representing its member states), NSF (USA), and NINS (Japan), together with NRC (Canada), MOST, and ASIAA (Taiwan), and KASI (Republic of Korea), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO, and NAOJ. Some of the data reported here are based on observations obtained at the Hale Telescope, Palomar Observatory as part of a continuing collaboration between the California Institute of Technology, NASA/JPL, Yale University, and the National Astronomical Observatories of China. This research made use of Photutils, an Astropy package for detection and photometry of astronomical sources (Bradley et al. 2019). G.V.P. acknowledges support by NASA through the NASA Hubble Fellowship grant #HST-HF2-51444.001-A awarded by the Space Telescope Science Institute, which is operated by the Association of Universities for Research in Astronomy, Inc., under NASA contract NAS5-26555. The data in this study include observations made with the Nordic Optical Telescope, owned in collaboration by the University of Turku and Aarhus University, and operated jointly by Aarhus University, the University of Turku, and the University of Oslo, representing Denmark, Finland, and Norway, the University of Iceland and Stockholm University at the Observatorio del Roque de los Muchachos, La Palma, Spain, of the Instituto de Astrofisica de Canarias. The data presented here were obtained in part with ALFOSC, which is provided by the Instituto de Astrofísica de Andalucía (IAA) under a joint agreement with the University of Copenhagen and NOT. E.L. was supported by Academy of Finland projects 317636 and 320045. Part of the French contribution is supported by the Scientific Research National Center (CNRS) and the French Spatial Agency (CNES). Some of the data are based on observations collected at the Observatorio de Sierra Nevada, owned and operated by the Instituto de Astrofísica de Andalucía (IAA-CSIC). Further data are based on observations collected at the Centro Astronómico Hispano-Alemán (CAHA), operated jointly by Junta de Andalucía and Consejo Superior de Investigaciones Científicas (IAA-CSIC). D.B., S.K., R.S., and N. M. acknowledge support from the European Research Council (ERC) under the European Unions Horizon 2020 research and innovation program under grant agreement No. 771282. C.C. acknowledges support by the European Research Council (ERC) under the HORIZON ERC Grants 2021 program under grant agreement No. 101040021. The Dipol-2 polarimeter was built in cooperation by the University of Turku, Finland, and the Leibniz Institut für Sonnenphysik, Germany, with support from the Leibniz Association grant SAW-2011-KIS-7. We are grateful to the Institute for Astronomy, University of Hawaii, for the allocated observing time. A.H. acknowledges The National Radio Astronomy Observatory is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc. This work was supported by JST, the establishment of university fellowships toward the creation of science technology innovation; grant No. JPMJFS2129. This work was supported by Japan Society for the Promotion of Science (JSPS) KAKENHI grant Nos. JP21H01137. This work was also partially supported by Optical and Near-Infrared Astronomy Inter-University Cooperation Program from the Ministry of Education, Culture, Sports, Science and Technology (MEXT) of Japan.With funding from the Spanish government through the "Severo Ochoa Centre of Excellence" accreditation (CEX2021-001131-S).Peer reviewe

X-Ray Polarization of BL Lacertae in Outburst

Full list of authors: Peirson, Abel L.; Negro, Michela; Liodakis, Ioannis; Middei, Riccardo; Kim, Dawoon E.; Marscher, Alan P.; Marshall, Herman L.; Pacciani, Luigi; Romani, Roger W.; Wu, Kinwah; Di Marco, Alessandro; Di Lalla, Niccolo; Omodei, Nicola; Jorstad, Svetlana G.; Agudo, Ivan; Kouch, Pouya M.; Lindfors, Elina; Aceituno, Francisco Jose; Bernardos, Maria I.; Bonnoli, Giacomo; Casanova, Victor; Garcia-Comas, Maya; Agis-Gonzalez, Beatriz; Husillos, Cesar; Marchini, Alessandro; Sota, Alfredo; Casadio, Carolina; Escudero, Juan; Myserlis, Ioannis; Sievers, Albrecht; Gurwell, Mark; Rao, Ramprasad; Imazawa, Ryo; Sasada, Mahito; Fukazawa, Yasushi; Kawabata, Koji S.; Uemura, Makoto; Mizuno, Tsunefumi; Nakaoka, Tatsuya; Akitaya, Hiroshi; Cheong, Yeon; Jeong, Hyeon-Woo; Kang, Sincheol; Kim, Sang-Hyun; Lee, Sang-Sung; Angelakis, Emmanouil; Kraus, Alexander; Cibrario, Nicolo; Donnarumma, Immacolata; Poutanen, Juri; Tavecchio, Fabrizio; Antonelli, Lucio A.; Bachetti, Matteo; Baldini, Luca; Baumgartner, Wayne H.; Bellazzini, Ronaldo; Bianchi, Stefano; Bongiorno, Stephen D.; Bonino, Raffaella; Brez, Alessandro; Bucciantini, Niccolo; Capitanio, Fiamma; Castellano, Simone; Cavazzuti, Elisabetta; Chen, Chien-Ting; Ciprini, Stefano; Costa, Enrico; De Rosa, Alessandra; Del Monte, Ettore; Di Gesu, Laura; Doroshenko, Victor; Dovciak, Michal; Ehlert, Steven R.; Enoto, Teruaki; Evangelista, Yuri; Fabiani, Sergio; Ferrazzoli, Riccardo; Garcia, Javier A.; Gunji, Shuichi; Hayashida, Kiyoshi; Heyl, Jeremy; Iwakiri, Wataru; Kaaret, Philip; Karas, Vladimir; Kitaguchi, Takao; Kolodziejczak, Jeffery J.; Krawczynski, Henric; La Monaca, Fabio; Latronico, Luca; Madejski, Grzegorz; Maldera, Simone; Manfreda, Alberto; Marin, Frederic; Marinucci, Andrea; Massaro, Francesco; Matt, Giorgio; Mitsuishi, Ikuyuki; Muleri, Fabio; Ng, C. -Y.; O'Dell, Stephen L.; Oppedisano, Chiara; Papitto, Alessandro; Pavlov, George G.; Perri, Matteo; Pesce-Rollins, Melissa; Petrucci, Pierre-Olivier; Pilia, Maura; Possenti, Andrea; Puccetti, Simonetta; Ramsey, Brian D.; Rankin, John; Ratheesh, Ajay; Roberts, Oliver J.; Sgro, Carmelo; Slane, Patrick; Soffitta, Paolo; Spandre, Gloria; Swartz, Douglas A.; Tamagawa, Toru; Taverna, Roberto; Tawara, Yuzuru; Tennant, Allyn F.; Thomas, Nicholas E.; Tombesi, Francesco; Trois, Alessio; Tsygankov, Sergey; Turolla, Roberto; Vink, Jacco; Weisskopf, Martin C.; Xie, Fei; Zane, Silvia.--This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.We report the first >99% confidence detection of X-ray polarization in BL Lacertae. During a recent X-ray/γ-ray outburst, a 287 ks observation (2022 November 27–30) was taken using the Imaging X-ray Polarimetry Explorer (IXPE), together with contemporaneous multiwavelength observations from the Neil Gehrels Swift observatory and XMM-Newton in soft X-rays (0.3–10 keV), NuSTAR in hard X-rays (3–70 keV), and optical polarization from the Calar Alto and Perkins Telescope observatories. Our contemporaneous X-ray data suggest that the IXPE energy band is at the crossover between the low- and high-frequency blazar emission humps. The source displays significant variability during the observation, and we measure polarization in three separate time bins. Contemporaneous X-ray spectra allow us to determine the relative contribution from each emission hump. We find >99% confidence X-ray polarization {{\rm{\Pi }}}_{2\mbox{--}4\mathrm{keV}}={21.7}_{-7.9}^{+5.6} \% and electric vector polarization angle ψ2–4keV = −28fdg7 ± 8fdg7 in the time bin with highest estimated synchrotron flux contribution. We discuss possible implications of our observations, including previous IXPE BL Lacertae pointings, tentatively concluding that synchrotron self-Compton emission dominates over hadronic emission processes during the observed epochs. © 2023. The Author(s). Published by the American Astronomical Society.The Imaging X-ray Polarimetry Explorer (IXPE) is a joint US and Italian mission. The US contribution is supported by the National Aeronautics and Space Administration (NASA) and led and managed by its Marshall Space Flight Center (MSFC), with industry partner Ball Aerospace (contract NNM15AA18C). The Italian contribution is supported by the Italian Space Agency (Agenzia Spaziale Italiana, ASI) through contract ASI-OHBI-2017-12-I.0, agreements ASI-INAF-2017-12-H0 and ASI-INFN-2017.13-H0, and its Space Science Data Center (SSDC) with agreements ASI-INAF-2022-14-HH.0 and ASI-INFN 2021-43-HH.0, and by the Istituto Nazionale di Astrofisica (INAF) and the Istituto Nazionale di Fisica Nucleare (INFN) in Italy. This research used data products provided by the IXPE Team (MSFC, SSDC, INAF, and INFN) and distributed with additional software tools by the High-Energy Astrophysics Science Archive Research Center (HEASARC), at NASA Goddard Space Flight Center (GSFC). Funding for this work was provided in part by contract 80MSFC17C0012 from the MSFC to MIT in support of the IXPE project. Support for this work was provided in part by the NASA through the Smithsonian Astrophysical Observatory (SAO) contract SV3-73016 to MIT for support of the Chandra X-Ray Center (CXC), which is operated by SAO for and on behalf of NASA under contract NAS8-03060. The IAA-CSIC coauthors acknowledge financial support from the Spanish "Ministerio de Ciencia e Innovación" (MCIN/AEI/10.13039/501100011033) through the Center of Excellence Severo Ochoa award for the Instituto de Astrofíisica de Andalucía-CSIC (CEX2021-001131-S), and through grants PID2019-107847RB-C44 and PID2022-139117NB-C44. Some of the data are based on observations collected at the Observatorio de Sierra Nevada, owned and operated by the Instituto de Astrofísica de Andalucía (IAA-CSIC). Further data are based on observations collected at the Centro Astronómico Hispano-Alemán (CAHA), operated jointly by Junta de Andalucía and Consejo Superior de Investigaciones Científicas (IAA-CSIC). The POLAMI observations were carried out at the IRAM 30 m Telescope. I.R.A.M. is supported by INSU/CNRS (France), MPG (Germany), and IGN (Spain). The Submillimetre Array is a joint project between the Smithsonian Astrophysical Observatory and the Academia Sinica Institute of Astronomy and Astrophysics and is funded by the Smithsonian Institution and the Academia Sinica. Maunakea, the location of the SMA, is a culturally important site for the indigenous Hawaiian people; we are privileged to study the cosmos from its summit. The data in this study include observations made with the Nordic Optical Telescope, owned in collaboration by the University of Turku and Aarhus University, and operated jointly by Aarhus University, the University of Turku, and the University of Oslo, representing Denmark, Finland, and Norway, the University of Iceland, and Stockholm University at the Observatorio del Roque de los Muchachos, La Palma, Spain, of the Instituto de Astrofisica de Canarias. The data presented here were obtained in part with ALFOSC, which is provided by the Instituto de Astrofísica de Andalucía (IAA) under a joint agreement with the University of Copenhagen and NOT. E.L. was supported by Academy of Finland projects 317636 and 320045. We acknowledge funding to support our NOT observations from the Finnish Centre for Astronomy with ESO (FINCA), University of Turku, Finland (Academy of Finland grant nr 306531). The research at Boston University was supported in part by National Science Foundation grant AST-2108622, NASA Fermi Guest Investigator grants 80NSSC21K1917 and 80NSSC22K1571, and NASA Swift Guest Investigator grant 80NSSC22K0537. This study used observations conducted with the 1.8 m Perkins Telescope Observatory (PTO) in Arizona (USA), which is owned and operated by Boston University. The above study is based in part on observations obtained with XMM-Newton, an ESA science mission with instruments and contributions directly funded by ESA Member States and NASA. We are grateful to the NuSTAR team for approving our DDT request. This work was supported under NASA contract No. NNG08FD60C, and made use of data from the NuSTAR mission, a project led by the California Institute of Technology, managed by the Jet Propulsion Laboratory, and funded by the NASA. This research has made use of the NuSTAR Data Analysis Software (NuSTARDAS) jointly developed by the ASI Science Data Center (ASDC, Italy) and the California Institute of Technology (USA). This work was supported by JST, the establishment of university fellowships toward the creation of science technology innovation, grant No. JPMJFS2129. This work was supported by Japan Society for the Promotion of Science (JSPS) KAKENHI grant No. JP21H01137. This work was also partially supported by Optical and Near-Infrared Astronomy Inter-University Cooperation Program from the Ministry of Education, Culture, Sports, Science, and Technology (MEXT) of Japan. We are grateful to the observation and operating members of Kanata Telescope. M.N. acknowledges the support by NASA under award number 80GSFC21M0002. C.C. acknowledges support by the ERC under the Horizon ERC Grants 2021 program under grant agreement no. 101040021. S.K., S.-S.L., W.Y.C., S.-H.K., and H.-W.J. were supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MIST; 2020R1A2C2009003). The KVN is a facility operated by the Korea Astronomy and Space Science Institute. The KVN operations are supported by KREONET (Korea Research Environment Open NETwork), which is managed and operated by KISTI (Korea Institute of Science and Technology Information). Partly based on observations with the 100 m telescope of the MPIfR (Max-Planck-Institut für Radioastronomie) at Effelsberg. Observations with the 100 m radio telescope at Effelsberg have received funding from the European Union's Horizon 2020 research and innovation program under grant agreement No 101004719 (ORP). A.L.P. acknowledges support from NASA FINESST grant 80NSSC19K1407 and the Stanford Data Science Scholars program.Peer reviewe

Integración de recursos electrónicos en las bibliotecas del Consorcio de Bibliotecas Universitarias de Andaluzas (CBUA)

En los últimos años, el presupuesto en recursos electrónicos ha ido creciendo paulatinamente en las Bibliotecas Universitarias y como consecuencia las inversiones en este tipo de materiales han ido aumentando, convirtiéndose hoy día la Biblioteca Universitaria en una gran factoría virtual. El Consorcio de Bibliotecas Universitarias Andaluzas (CBUA) que asume entre sus políticas el desarrollo de proyectos para la mejora de la calidad de los servicios a través de la cooperación, consciente de esta situación, acomete el plan de dotar a las Bibliotecas del Consorcio de tecnologías centradas en el usuario, para hacer más accesibles las colecciones de recursos electrónicos y poder competir en la Europa del conocimiento con parámetros de calidad. Se presenta el proyecto que está llevando a cabo el Grupo de Trabajo de MAP y ERM del CBUA, de implementación y puesta en marcha de herramientas, para el acceso, integración y gestión de los recursos electrónicos en las Bibliotecas Universitarias Andaluzas, para un mejor uso de las colecciones digitales contratadas, que redundará en la calidad y mejora de los servicios prestados. Se enumeran las fases del proyecto, los objetivos operativos, las líneas de acción, las acciones realizadas, la documentación generada, la difusión y formación en las nuevas herramientas y la repercusión que está teniendo en las Bibliotecas del CBU