Factors affecting trueness of intraoral scans : an update

Background: Intraoral scanning (IOS) technologies have been constantly developed and improved. This systematic review aimed at assessing studies in the recent literature describing factors that influence the trueness of intraoral scans. Methods: Comparative in vitro and in vivo (i.e., interventional and observational) studies that quantitatively assessed the trueness of intraoral scans and that identified factors significantly affecting IOS trueness values were considered eligible for inclusion. The PUBMED and EMBASE databases were searched for articles published in the last two years (from February 2020 to February 2022). Data assessment and extraction were performed according to the guidelines of the PRISMA statement. Results: The present search strategy yielded 13 publications. An initial screening of the publications was performed using abstracts and key words, and after application of exclusion criteria, a total of nine studies were finally identified as eligible to be discussed. Several factors significantly affecting IOS were identified. Conclusions: Studies using current IOS technologies revealed that the device, scanning distance, operator experience, rescanning and post-processing scans, conditions of the preparations and presence of adjacent teeth are factors significantly affecting IOS trueness.peer-reviewe

The oral health status of the Gozitan community

The objective of this study is to assess the oral health status and treatment needs of Gozo residents – a geographically isolated community. A cross-sectional study of 332 Gozitan attendees on the Mobile Dental Unit was carried out during a three-month period in 14 localities in Gozo. The participants attended for a dental check-up and indices were used to record caries, plaque, calculus, erosion, soft tissue pathologies and number of dental functional units. Of the 332 participants 76.8% presented with plaque deposits, 78% require either restorative or periodontal treatment while signs of erosive wear were present in 28% of participants. In younger age bands (0–9 and 10–19) untreated carious lesions amount to 1.34 and 1.0 (DT portion of DMFT) respectively, care index FT (filled teeth)/DMFT was 0.37 overall. Most participants in 50+ age bands had less than 10 remaining functional units. Thus, the oral health status of the Gozitan community shows a high level of unmet dental treatment needs. This underscores the need for provision of better dental services in Gozo, re-orientation of existing services to focus on prevention, and introduction of evidence-based preventive strategies in school-children.peer-reviewe

The correlation between the level of knowledge in reading nutritional labels and oral health

Abstract and Objectives: To establish whether the level of knowledge in reading nutritional labels in the Maltese population is correlated to their oral health status. Materials and Methods: Participants were recruited from dental screenings on the Mobile Dental Unit (MDU) or at the University of Malta dental teaching clinics. A questionnaire was used to collect general information, participants’ awareness of WHO sugar guidelines, food preferences, and their level of knowledge in reading nutrition labels. The decayed, missing, and filled teeth (DMFT) Index and erosion scores were also recorded. Results: A total of 122 random subjects participated in this research project, of which 62.3% were females. 17.2% of the total sample were aware of the WHO guidelines regarding sugar intake. 41.7% of people showed a good level of knowledge in reading nutrition labels. Mean DMFT scores and care index were found to be 10.5 ± 7.2 and 37.2 ± 30.3% respectively. Furthermore, the BEWE index was found to be 1.2 ± 3.3%. Higher educational levels were associated with healthier diets. Within the 35-65 years group, DMFT was significantly lower if the respondent had the ability to read labels. Conclusion: The study showed that there is a low awareness of WHO daily sugar intake guidelines and a moderate understanding of nutrition labels. Age-related trends, educational background, and knowledge in reading and correctly understanding food nutritional labels were related to better oral health.peer-reviewe

Hypovitaminosis D is associated with depression and anxiety in schizophrenia: results from the national FACE-SZ cohort. Running title: hypovitaminosis D, depression and anxiety in schizophrenia

International audienceBackground. Guidelines have been edited for the treatment of schizophrenia (SZ) and bipola

Interest of Human Papillomavirus DNA quantification and genotyping in paired cervical and urine samples to detect cervical lesions

International audienceBackgroundCervical cancer is caused by persistent infection with high-risk human papillomavirus (HR-HPV). Conventional human papillomavirus (HPV) testing requires cervical sampling. However, vaginal and urine self-sampling methods are more acceptable for patients and result in increased participation when they are available in screening programs. In this context, we have developed a non-invasive screening method via the detection of HPV DNA in urine samples.PurposeTo compare HPV viral loads and genotypes in paired cervical and urine samples, and to assess correlation between virological and cytological results in women seeking gynecological consultation.MethodsPaired urine and cervical specimens were collected and analyzed from 230 of 245 women participating in the previously described prospective PapU study. HPV DNA detection and quantification were performed using a real-time PCR method with short fragment PCR primers. Genotyping was carried out using the INNO-LiPA HPV genotyping assay.ResultsThe prevalence of HPV in the 230 paired urine and cervical smear samples was 42 and 49&nbsp;%, respectively. Overall agreement for HPV positivity and negativity between the paired samples was 90&nbsp;% (κ&nbsp;=&nbsp;0.80). High HPV viral load in both cervical and urine samples was associated with cytological abnormalities. HPV-positive women were mostly infected with HR-HPV types. The agreement between high- and low-risk HPV (LR-HPV) detection in both samples was 97&nbsp;% (κ&nbsp;=&nbsp;0.95 for HR-HPV and κ&nbsp;=&nbsp;0.97 for LR-HPV).ConclusionsHigh concordance rates for HPV-DNA quantification and high/low-risk HPV genotyping in paired urine/cervical samples suggest that urinary HPV DNA testing could be useful for cervical lesion screening.</p

Interest of Human Papillomavirus DNA quantification and genotyping in paired cervical and urine samples to detect cervical lesions

International audienceBackgroundCervical cancer is caused by persistent infection with high-risk human papillomavirus (HR-HPV). Conventional human papillomavirus (HPV) testing requires cervical sampling. However, vaginal and urine self-sampling methods are more acceptable for patients and result in increased participation when they are available in screening programs. In this context, we have developed a non-invasive screening method via the detection of HPV DNA in urine samples.PurposeTo compare HPV viral loads and genotypes in paired cervical and urine samples, and to assess correlation between virological and cytological results in women seeking gynecological consultation.MethodsPaired urine and cervical specimens were collected and analyzed from 230 of 245 women participating in the previously described prospective PapU study. HPV DNA detection and quantification were performed using a real-time PCR method with short fragment PCR primers. Genotyping was carried out using the INNO-LiPA HPV genotyping assay.ResultsThe prevalence of HPV in the 230 paired urine and cervical smear samples was 42 and 49&nbsp;%, respectively. Overall agreement for HPV positivity and negativity between the paired samples was 90&nbsp;% (κ&nbsp;=&nbsp;0.80). High HPV viral load in both cervical and urine samples was associated with cytological abnormalities. HPV-positive women were mostly infected with HR-HPV types. The agreement between high- and low-risk HPV (LR-HPV) detection in both samples was 97&nbsp;% (κ&nbsp;=&nbsp;0.95 for HR-HPV and κ&nbsp;=&nbsp;0.97 for LR-HPV).ConclusionsHigh concordance rates for HPV-DNA quantification and high/low-risk HPV genotyping in paired urine/cervical samples suggest that urinary HPV DNA testing could be useful for cervical lesion screening.</p