363 research outputs found

    Estilos de aprendizaje y salud mental en estudiantes de educación superior tecnológica

    Get PDF
    Introduction: Academic success turns out to be a life goal for many young people in technological higher education, where factors such as learning styles intervene, which facilitate the understanding of their cognitive, affective and physiological characteristics with which they perceive and respond to a learning scenario. On the other hand, mental health is conceived as fundamental for human well-being. Understanding these variables allows students and teachers to organize and plan an optimal teaching-learning process. Objectives: to identify the learning styles most used in the population; to establish the mental health scales by gender and to determine correlations between the variables under study. Methodology: a quantitative approach was used with a basic purpose to know the nature of the variables, the data source was from the field, with a non-experimental cross-sectional design, its scope was descriptive and correlational, an analytical method was established. Results: significant differences were found (p<0.05) in the use of learning styles between men and women in the Active-Reflective, Visual-Verbal and Sensory-Intuitive scales. Likewise, when analyzing mental health by gender, women presented a greater number of symptoms than men, thus, in the category “Somatic symptoms” a difference of 25.9 % to 9.8 % was found; in “Anxiety-Insomnia” from 31.3 to 17.4; in “Social dysfunction” from 17.2 % to 7.5 % and in “Depression” from 15.1 % to 9.1 %. It was further determined that “Active-Reflective” and “Sequential-Global” learning styles possessed a stronger negative correlation with mental health. Conclusions: Finally, it was concluded that the female population presents greater alteration in their mental health, probably influenced by learning styles.Introducción: El éxito académico resulta un objetivo de vida para muchos jóvenes en la educación superior tecnológica, donde intervienen factores como los estilos de aprendizaje que facilitan la comprensión de sus características cognitivas, afectivas y fisiológicas con las que perciben y responden a un escenario de aprendizaje. Por otro lado, la salud mental se concibe como fundamental para el bienestar humano. Comprender estas variables permite a estudiantes y docentes organizar y planear un óptimo proceso de enseñanza-aprendizaje. Objetivos: Identificar los estilos de aprendizaje más utilizados en la población; establecer las escalas de salud mental por género y determinar correlaciones entre las variables de estudio. Metodología: se empleó un enfoque cuantitativo con una finalidad básica para conocer la naturaleza de las variables, la fuente de datos fue de campo, con un diseño no experimental de tipo transversal, su alcance fue descriptivo y correlacional, se estableció un método analítico. Resultados: se halló diferencias significativas (p<0,05) del uso de estilos de aprendizaje entre hombres y mujeres en las escalas Activo-Reflexivo, Visual-Verbal y Sensorial-Intuitivo. Asimismo, al analizar la salud mental por género, las mujeres presentaron mayor número de síntomas que los hombres, es así como, en la categoría “Síntomas somáticos” se constató una diferencia de 25,9 % a 9,8 %; en “Ansiedad-Insomnio” de 31,3 a 17, 4; en “Disfunción social” de 17,2 % a 7,5 % y en “Depresión” de 15,1 % a 9,1 %. Se determinó, además, que los estilos de aprendizaje “Activo-Reflexivo” y “Secuencial-Global” poseyeron una correlación negativa más fuerte con la salud mental. Conclusiones: Finalmente, se concluyó que la población femenina presenta mayor alteración en su salud mental, probablemente influenciada por los estilos de aprendizaje

    Estilos de aprendizaje y salud mental en estudiantes de educación superior tecnológica

    Get PDF
    Introduction: Academic success turns out to be a life goal for many young people in technological higher education, where factors such as learning styles intervene, which facilitate the understanding of their cognitive, affective and physiological characteristics with which they perceive and respond to a learning scenario. On the other hand, mental health is conceived as fundamental for human well-being. Understanding these variables allows students and teachers to organize and plan an optimal teaching-learning process. Objectives: to identify the learning styles most used in the population; to establish the mental health scales by gender and to determine correlations between the variables under study. Methodology: a quantitative approach was used with a basic purpose to know the nature of the variables, the data source was from the field, with a non-experimental cross-sectional design, its scope was descriptive and correlational, an analytical method was established. Results: significant differences were found (p<0.05) in the use of learning styles between men and women in the Active-Reflective, Visual-Verbal and Sensory-Intuitive scales. Likewise, when analyzing mental health by gender, women presented a greater number of symptoms than men, thus, in the category “Somatic symptoms” a difference of 25.9 % to 9.8 % was found; in “Anxiety-Insomnia” from 31.3 to 17.4; in “Social dysfunction” from 17.2 % to 7.5 % and in “Depression” from 15.1 % to 9.1 %. It was further determined that “Active-Reflective” and “Sequential-Global” learning styles possessed a stronger negative correlation with mental health. Conclusions: Finally, it was concluded that the female population presents greater alteration in their mental health, probably influenced by learning styles.Introducción: El éxito académico resulta un objetivo de vida para muchos jóvenes en la educación superior tecnológica, donde intervienen factores como los estilos de aprendizaje que facilitan la comprensión de sus características cognitivas, afectivas y fisiológicas con las que perciben y responden a un escenario de aprendizaje. Por otro lado, la salud mental se concibe como fundamental para el bienestar humano. Comprender estas variables permite a estudiantes y docentes organizar y planear un óptimo proceso de enseñanza-aprendizaje. Objetivos: Identificar los estilos de aprendizaje más utilizados en la población; establecer las escalas de salud mental por género y determinar correlaciones entre las variables de estudio. Metodología: se empleó un enfoque cuantitativo con una finalidad básica para conocer la naturaleza de las variables, la fuente de datos fue de campo, con un diseño no experimental de tipo transversal, su alcance fue descriptivo y correlacional, se estableció un método analítico. Resultados: se halló diferencias significativas (p<0,05) del uso de estilos de aprendizaje entre hombres y mujeres en las escalas Activo-Reflexivo, Visual-Verbal y Sensorial-Intuitivo. Asimismo, al analizar la salud mental por género, las mujeres presentaron mayor número de síntomas que los hombres, es así como, en la categoría “Síntomas somáticos” se constató una diferencia de 25,9 % a 9,8 %; en “Ansiedad-Insomnio” de 31,3 a 17, 4; en “Disfunción social” de 17,2 % a 7,5 % y en “Depresión” de 15,1 % a 9,1 %. Se determinó, además, que los estilos de aprendizaje “Activo-Reflexivo” y “Secuencial-Global” poseyeron una correlación negativa más fuerte con la salud mental. Conclusiones: Finalmente, se concluyó que la población femenina presenta mayor alteración en su salud mental, probablemente influenciada por los estilos de aprendizaje

    A IMPORTÂNCIA DA GESTÃO DO TURNOVER

    Get PDF
    Este trabalho tem como objetivo demonstrar qual a importância da gestão de turnover para a área de Recursos Humanos e como é importante que as organizações tenham alguém que faça este controle de rotatividade, este que pode ser medido em índice geral ou por partes, dependendo das necessidades da organização. Para obtenção de dados, optou-se por um estudo teórico baseado nas ideias dos autores Lacombe (2011), Bichuetti(2011), Marras (2000), Lucena (2007), Chiavenato (1999), Martins (2014) e uma pesquisa de campo, utilizando como ferramentas de coleta um questionário com perguntas abertas, semiabertas e fechadas, aplicadas a dois profissionais que realizam o controle de turnover em empresas localizadas na região de Joinville/SC

    Mercadeo con base en las ciencias de la complejidad y la lógica difusa

    Get PDF
    El presente documento pretender ilustrar el trabajo realizado por la Facultad de Administración para con la Sociedad Hotelera Tequendama y en el cual se han utilizado herramientas conceptualmente avanzadas para el estudio y definición de los mercados de la Empresa y la enunciación de grandes líneas estratégicas para la mejor operatividad comercial de la sociedad. La Facultad de Administración de la Universidad del Rosario (UR) conjuntamente con la Sociedad Hotelera Tequendama acordaron realizar una investigación sobre el comportamiento del usuario (huésped), operaciones y mercadeo del Hotel y las Aparta-Suites Tequendama, con base en lógica difusa y las ciencias de la complejidad, que constituyen los ejes del trabajo académico, de investigación y de consultoría de la Facultad. El trabajo se ha denominado: Estudio de mercados dirigido al alojamiento en Bogotá de la sociedad hotelera Tequendama bajo lógica difusa en función de la optimización y la capacidad instalada, que a partir de las conclusiones, recomendaciones expuestas en los informes pasados, brindaría la acción estratégica, que se acompañan de un esquema sumarial al final. La investigación se llevó a cabo durante tres meses, arrojando, finalmente, el conjunto de las conclusiones, recomendaciones y acción estratégica en el futuro inmediato. De este documento de Trabajo se ha suprimido, deliberadamente, toda información confidencial que pudiera perjudicar en algún sentido la imagen del Hotel Tequendama

    Mutanome and expression of immune response genes in microsatellite stable colon cancer

    Get PDF
    The aim of this study was to analyze the impact of the mutanome in the prognosis of microsatellite stable stage II CRC tumors. The exome of 42 stage II, microsatellite stable, colon tumors (21 of them relapse) and their paired mucosa were sequenced and analyzed. Although some pathways accumulated more mutations in patients exhibiting good or poor prognosis, no single somatic mutation was associated with prognosis. Exome sequencing data is also valuable to infer tumor neoantigens able to elicit a host immune response. Hence, putative neoantigens were identified by combining information about missense mutations in each tumor and HLAs genotypes of the patients. Under the hypothesis that neoantigens should be correctly presented in order to activate the immune response, expression levels of genes involved in the antigen presentation machinery were also assessed. In addition, CD8A level (as a marker of T-cell infiltration) was measured. We found that tumors with better prognosis showed a tendency to generate a higher number of immunogenic epitopes, and up-regulated genes involved in the antigen processing machinery. Moreover, tumors with higher T-cell infiltration also showed better prognosis. Stratifying by consensus molecular subtype, CMS4 tumors showed the highest association of expression levels of genes involved in the antigen presentation machinery with prognosis. Thus, we hypothesize that a subset of stage II microsatellite stable CRC tumors are able to generate an immune response in the host via MHC class I antigen presentation, directly related with a better prognosis

    Degradação de biofilme de proteína de soro de leite em diferentes tipos de solos

    Get PDF
    Biofilmes são preparados a partir de materiais biológicos ou polímeros, e agem como barreira a elementos externos, tais como umidade, fatores físicos e biológicos, na qual, essa barreira além de proteger o produto embalado, aumenta seu tempo de prateleira. As proteínas do soro de leite têm sido utilizadas em diversas aplicações alimentícias, devido às suas propriedades funcionais, tais como, a gelatinização, solubilidade, dentre outros. Desta forma, o soro de leite deixou de ser encarado como um resíduo industrial que acarreta graves problemas ambientais associados ao seu alto teor de matéria orgânica e passou a ser visto como uma potencial matéria-prima. O presente trabalho objetivou avaliar o tempo de degradação de biofilme produzido a partir da proteína de leite, em solos que apresentam diferentes tipos de microrganismos, sendo os solos: latossolo vermelho ácrico e gleissolo melânico órtico. Os biofilmes foram produzidos a partir do método de casting e foram caracterizadas através das técnicas análises de umidade, solubilidade em água e Microscopia Eletrônica de Varredura. Os biofilmes apresentaram umidade média de 14,14% e alta solubilidade de 35,98%. Após 15 dias de acondicionamento dos biofilmes nos diferentes solos, foi observada sua degradação. O período de degradação dos biofilmes foi curto, e pode ser relacionado mais com o teor de umidade do solo do que com a microbiota presente no mesmoFil: Santos da Silva, Fábio. Universidad Federal de Goiás (Brasil)Fil: Ramos Silvério, Loren. Universidad Federal de Goiás (Brasil)Fil: Teixeira Melo Pereira, Luana. Universidad Federal de Goiás (Brasil)Fil: Ferreira Moreno, Isabela. Universidad Federal de Goiás (Brasil)Fil: Régia Marques de Souza, Adriana. Universidad Federal de Goiás (Brasil

    Combination of Pneumococcal Surface Protein A (PspA) with Whole Cell Pertussis Vaccine Increases Protection Against Pneumococcal Challenge in Mice

    Get PDF
    Streptococcus pneumoniae is the leading cause of respiratory acute infections around the world. In Latin America, approximately 20,000 children under 5 years of age die of pneumococcal diseases annually. Pneumococcal surface protein A (PspA) is among the best-characterized pneumococcal antigens that confer protection in animal models of pneumococcal infections and, as such, is a good alternative for the currently available conjugated vaccines. Efficient immune responses directed to PspA in animal models have already been described. Nevertheless, few low cost adjuvants for a subunit pneumococcal vaccine have been proposed to date. Here, we have tested the adjuvant properties of the whole cell Bordetella pertussis vaccine (wP) that is currently part of the DTP (diphtheria-tetanus-pertussis) vaccine administrated to children in several countries, as an adjuvant to PspA. Nasal immunization of BALB/c mice with a combination of PspA5 and wP or wPlow – a new generation vaccine that contains low levels of B. pertussis LPS – conferred protection against a respiratory lethal challenge with S. pneumoniae. Both PspA5-wP and PspA5-wPlow vaccines induced high levels of systemic and mucosal antibodies against PspA5, with similar profile, indicating no essential requirement for B. pertussis LPS in the adjuvant properties of wP. Accordingly, nasal immunization of C3H/HeJ mice with PspA5-wP conferred protection against the pneumococcal challenge, thus ruling out a role for TLR4 responses in the adjuvant activity and the protection mechanisms triggered by the vaccines. The high levels of anti-PspA5 antibodies correlated with increased cross-reactivity against PspAs from different clades and also reflected in cross-protection. In addition, passive immunization experiments indicated that antibodies played an important role in protection in this model. Finally, subcutaneous immunization with a combination of PspA5 with DTPlow protected mice against challenge with two different pneumococcal strains, opening the possibility for the development of a combined infant vaccine composed of DTP and PspA

    Efficacy of ethyl alcohol and quaternary ammonium in hospital medical equipment disinfection

    Get PDF
    Background and Objectives: Hospital environments may harbor pathogenic and opportunistic microorganisms, and the cleaning and disinfection process is important for the control of Health Care Related Infections (IRAS). Thus, the objective of this work to evaluate compare the efficacy of ethyl alcohol and quaternary ammonium in the disinfection of hospital medical equipment against Staphylococcus aureus (S. aureus). Methods: decontamination of 10 hospital medical equipment contaminated with a suspension of S. aureus ATCC 25923. The decontamination occurred with ethyl alcohol at concentrations of 46.2%, 70% and 99% and with the quaternary ammonium of 1st generation and 5th generation. After the decontamination, samples were harvested from the surface of the equipment for bacterial culture. Results: bacterial growth was verified in 80% of the equipment decontaminated with alcohol 46.2% and 99%. There was no bacterial growth on the surface of equipment decontaminated with alcohol 70% and quaternary ammonium. Conclusion: the disinfection processes with alcohol 70% and quaternary ammonium 1st and 5th generation were effective in the control of S. aureus, proving the effectiveness of these products in the disinfection of hospital medical equipment

    Eficácia do álcool etílico e quaternário de amônio na desinfecção de equipamentos médicos hospitalares

    Get PDF
    Background and Objectives: Hospital environments may harbor pathogenic and opportunistic microorganisms, and the cleaning and disinfection process is important for the control of Health Care Related Infections (IRAS). Thus, the objective of this work to evaluate compare the efficacy of ethyl alcohol and quaternary ammonium in the disinfection of hospital medical equipment against Staphylococcus aureus (S. aureus). Methods: decontamination of 10 hospital medical equipment contaminated with a suspension of S. aureus ATCC 25923. The decontamination occurred with ethyl alcohol at concentrations of 46.2%, 70% and 99% and with the quaternary ammonium of 1st generation and 5th generation. After the decontamination, samples were harvested from the surface of the equipment for bacterial culture. Results: bacterial growth was verified in 80% of the equipment decontaminated with alcohol 46.2% and 99%. There was no bacterial growth on the surface of equipment decontaminated with alcohol 70% and quaternary ammonium. Conclusions: the disinfection processes with alcohol 70% and quaternary ammonium 1st and 5th generation were effective in the control of S. aureus, proving the effectiveness of these products in the disinfection of hospital medical equipment.Antecedentes y objetivos: Los ambientes hospitalarios pueden albergar microorganismos patógenos y oportunistas, siendo el proceso de limpieza y desinfección importante para el control de las Infecciones relacionadas a la Asistencia a la Salud (IRAS). Así, el objetivo de este trabajo evaluar comparar la eficacia del alcohol etílico y del cuaternario de amonio en el proceso de desinfección de equipos médicos hospitalarios previamente contaminados con Staphylococcus aureus (S. aureus). Métodos: la descontaminación de 10 equipos médicos hospitalarios contaminados con una suspensión de S. aureus ATCC 25923. La descontaminación ocurrió con alcohol etílico en las concentraciones de 46,2%, 70% y 99% y con el cuaternario de amonio de 1ª y de 5ª generación. Después de la descontaminación, se tomaron muestras de la superficie de los equipos para cultivo bacteriano. Resultados: se verificó crecimiento bacteriano en el 80% de los equipos descontaminados con alcohol 46,2% y 99%. No hubo crecimiento bacteriano en la superficie de los equipos descontaminados con alcohol 70% y cuaternarios de amonio. Conclusión: los procesos de desinfección con alcohol 70% y cuaternario de amonio de 1ª y 5ª generación fueron eficaces en el control del S. aureus, comprobando la acción efectiva de estos productos en la desinfección de los equipos médicos hospitalarios.Justificativa e Objetivo: Os ambientes hospitalares podem albergar micro-organismos patogênicos e oportunistas, sendo o processo de limpeza e desinfecção importante para o controle das Infecções relacionadas à Assistência à Saúde (IRAS). Assim, o objetivo deste trabalho foi avaliar a eficácia do álcool etílico e do quaternário de amônio no processo de desinfecção de equipamentos médicos hospitalares previamente contaminados com Staphylococcus aureus (S. aureus). Método: descontaminação de 10 equipamentos médicos hospitalares contaminados com uma suspensão de S. aureus ATCC 25923. A descontaminação ocorreu com álcool etílico nas concentrações de 46,2%, 70% e 99% e com o quaternário de amônio de 1ª e de 5ª geração. Após a descontaminação, foram colhidas amostras da superfície dos equipamentos para cultura bacteriana. Resultados: foi verificado crescimento bacteriano em 80% dos equipamentos descontaminados com álcool 46,2% e 99%. Não houve crescimento bacteriano na superfície dos equipamentos descontaminados com álcool 70% e quaternários de amônio. Conclusão: os processos de desinfecção com álcool 70% e quaternário de amônio de 1ª e 5ª geração foram eficazes no controle do S. aureus, comprovando a ação efetiva destes produtos na desinfecção dos equipamentos médicos hospitalares

    Structural assessment, toxicity, and increased antimicrobial activity

    Get PDF
    Scorpion venom is a rich source of biologically active components and various peptides with high-potential therapeutic use that have been characterized for their antimicrobial and antiproliferative activities. Stigmurin is a peptide identified from the Tityus stigmurus venom gland with high antibacterial and antiproliferative activities and low toxicity. Amino acid substitutions in peptides without a disulfide bridge sequence have been made with the aim of reducing their toxicity and increasing their biological activities. The purpose of this study was to evaluate the structural conformation and structural stability, as well as antimicrobial, antiproliferative, and hemolytic activities of two peptide analogs to Stigmurin, denominated StigA6 and StigA16. In silico analysis revealed the α-helix structure for both analog peptides, which was confirmed by circular dichroism. Data showed that the net charge and hydrophobic moment of the analog peptides were higher than those for Stigmurin, which can explain the increase in antimicrobial activity presented by them. Both analog peptides exhibited activity on cancerous cells similar to the native peptide; however, they were less toxic when tested on the normal cell line. These results reveal a potential biotechnological application of the analog peptides StigA6 and StigA16 as prototypes to new therapeutic agents.publishersversionpublishe
    corecore