Técnicas de Extração de Informação para Avaliação da Qualidade de Páginas Web com o Uso de Ontologias

A qualidade dos conteúdos das páginas Web podem ser determinadas parcialmente através de indicadores como autoria do página, presença de referencias e de propriedade. Este artigo discute a aplicação de técnicas de extração de informação sobre a identificação de indicadores de qualidade, especificamente autoria. Ao contrário de outras técnicas de extração, as técnicas desenvolvidas neste trabalho não utilizam a estrutura da página como principal elemento de análise, voltando sua atenção para o conteúdo extraido. O objetivo final do trabalho é criar uma ferramenta que possibilita a avaliação da qualidade de sites de saúde. Com as entidades extraídas é populado uma ontologia onde estão definidos os critérios de qualidade para as páginas Web

Adrenergic Regulation of Drp1-Driven Mitochondrial Fission in Cardiac Physio-Pathology

Abnormal mitochondrial morphology, especially fragmented mitochondria, and mitochondrial dysfunction are hallmarks of a variety of human diseases including heart failure (HF). Although emerging evidence suggests a link between mitochondrial fragmentation and cardiac dysfunction, it is still not well described which cardiac signaling pathway regulates mitochondrial morphology and function under pathophysiological conditions such as HF. Mitochondria change their shape and location via the activity of mitochondrial fission and fusion proteins. This mechanism is suggested as an important modulator for mitochondrial and cellular functions including bioenergetics, reactive oxygen species (ROS) generation, spatiotemporal dynamics of Ca2+ signaling, cell growth, and death in the mammalian cell- and tissue-specific manners. Recent reports show that a mitochondrial fission protein, dynamin-like/related protein 1 (DLP1/Drp1), is post-translationally modified via cell signaling pathways, which control its subcellular localization, stability, and activity in cardiomyocytes/heart. In this review, we summarize the possible molecular mechanisms for causing post-translational modifications (PTMs) of DLP1/Drp1 in cardiomyocytes, and further discuss how these PTMs of DLP1/Drp1 mediate abnormal mitochondrial morphology and mitochondrial dysfunction under adrenergic signaling activation that contributes to the development and progression of HF

8-week-Old AJ and C57BL6J Morphologic, Mechanic, and Histomorphometric Raw Data

Please see Methods section of manuscript for trait abbreviations and measures from which raw values were derived

Dynamics of dissociative electron attachment to ammonia

Ab initio theoretical studies and momentum-imaging experiments are combined to provide a consistent picture of the dynamics of dissociative electron attachment to ammonia through its 5.5- and 10.5-eV resonance channels. The present study clarifies the character and symmetry of the anion states involved and the dynamics that leads to the observed fragment-ion channels, their branching ratios, and angular distributions

Dynamics of dissociative electron attachment to ammonia

Ab initio theoretical studies and momentum-imaging experiments are combined to provide a consistent picture of the dynamics of dissociative electron attachment to ammonia through its 5.5- and 10.5-eV resonance channels. The present study clarifies the character and symmetry of the anion states involved and the dynamics that leads to the observed fragment-ion channels, their branching ratios, and angular distributions