1,730 research outputs found

    Reconstruction of pre-Illinoian ice margins and glaciotectonic structures from airborne electromagnetic (AEM) surveys at the western limit of Laurentide glaciation, Midcontinent U.S.A.

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    Early and early Middle Pleistocene glaciations in midcontinental USA are poorly understood relative to more recent Illinoian and Wisconsinan glaciations, largely because pre-Illinoian glacial landforms and deposits are eroded and buried. In this paper, we present a new interpretation of buried, pre-Illinoian glacial features along the Laurentide glacial margin in northeastern Nebraska using Airborne ElectroMagnetics (AEM) supplemented with borehole logs and 2m LiDAR elevation data. We detect and map large-scale (101–102 km) geological features using contrasts in electrical resistivity. The Laurentide glacial limit is marked by a continuous (\u3e120 km) contrast between conductive (\u3c15 Ω-m), clayey tills and resistive (\u3e40 Ω-m) sandy sediments. Several smaller (102 km2) till salients extend 10s of km westward of this margin. We recognize a lithologically heterogeneous zone characterized by variable resistivity and complex geophysical structures extending as much as 17 km west of the glacial limit. This zone is interpreted as a glaciotectonic thrust complex, and it is analogous to a similar thrust complex in Denmark where structural analysis of co-located seismic and AEM surveys provides a standard for comparison. Our study suggests that the maximum advancement of pre-Illinoian glacial ice into Nebraska involved extensive deformation of sedimentary strata, local overriding of these deformed strata by smaller ice tongues, and emplacement of tills as much as 30 km west of the principal Laurentide ice margin. These insights provide the first glimpse of the large-scale stratigraphic architecture of glacial sediments in Nebraska and point to future clarifications of the geology and geomorphology of the Laurentide glacial limit

    Deep dissections of the veins of the bovine head : unpublished work by Prof. J.M.W. Le Roux (1926-1991)

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    The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.mn201

    Osteology of the thoracic limb of the African elephant (Loxodonta africana)

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    The forelimb bones of 8 elephants (7 adults, 1 juvenile) were studied. In addition, the bones of the digits were dissected and studied in situ in a mature specimen. The scapula, humerus and bones of the antebrachium (particularly the ulna) are massive in comparison to the short, relatively small bones of the manus. There are 8 carpal bones, 5 metacarpal bones and 5 digits. Digits 2-4 consist of 3 phalanges each. The 5th digit consists of 2 phalanges, while the 1st is represented by a single phalanx which is tusk-like and pointed. The distal phalanges of digits 2-4 are very small and do not articulate with the middle phalanges. The proximal sesamoids are well developed and are present on the palmar aspect of all 5 metacarpophalangeal joints. All the bones are illustrated from at least 2 aspects.The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.mn201

    Osteology of the pelvic limb of the African elephant (Loxodonta africana)

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    The pelvic girdle was characterized by large, transversely-placed ilial wings. The femur was the longest bone of the skeleton and its fovea capitis was situated caudomedially between the epiphyseal line and the articular surface of the femoral head. A wedge-shaped patella articulated with the femoral trochlea. The bones of the crus were approximately half as long as the femur and consisted of the sturdy tibia and slender fibula. The condyles of the tibia were concave and the femoro-tibial joint was congruent with rudimentary menisci. The tarsus consisted of seven bones which were arranged in three rows. There were five metatarsal bones. Only four digits were present, the third and fourth consisted of three phalanges each while the second and fourth digits were smaller and consisted of two phalanges each. The first digit was represented by one proximal sesamoid bone only. A large, cartilagenous rod or prehallux was attached to the first tarsal and metatarsal bones. Proximal sesamoid bones were present on the plantar aspect of the trochleae of metatarsal bones 1- V. The pes was found to be digitigrade and the digits rested on a thick pad of elastic connective tissue and fat.The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.mn201

    The Grizzly, April 1, 2015

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    UC Stand Plans New Multi-Gender Fashion Show • Woodstock Receives Award • Experiences from Model UN • Ursinus Alum is Succeeding in the Business World • Women and Minorities on Wikipedia Examined • Opinion: The Challenges of Transferring to Ursinus • Tennis Teams Ace Early Slatehttps://digitalcommons.ursinus.edu/grizzlynews/1929/thumbnail.jp

    Inter-model comparison of global hydroxyl radical (OH) distributions and their impact on atmospheric methane over the 2000–2016 period

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    The modeling study presented here aims to estimate how uncertainties in global hydroxyl radical (OH) distributions, variability, and trends may contribute to resolving discrepancies between simulated and observed methane (CH4) changes since 2000. A multi-model ensemble of 14 OH fields was analyzed and aggregated into 64 scenarios to force the offline atmospheric chemistry transport model LMDz (Laboratoire de Meteorologie Dynamique) with a standard CH4 emission scenario over the period 2000–2016. The multi-model simulated global volume-weighted tropospheric mean OH concentration ([OH]) averaged over 2000–2010 ranges between 8:7*10^5 and 12:8*10^5 molec cm-3. The inter-model differences in tropospheric OH burden and vertical distributions are mainly determined by the differences in the nitrogen oxide (NO) distributions, while the spatial discrepancies between OH fields are mostly due to differences in natural emissions and volatile organic compound (VOC) chemistry. From 2000 to 2010, most simulated OH fields show an increase of 0.1–0:3*10^5 molec cm-3 in the tropospheric mean [OH], with year-to-year variations much smaller than during the historical period 1960–2000. Once ingested into the LMDz model, these OH changes translated into a 5 to 15 ppbv reduction in the CH4 mixing ratio in 2010, which represents 7%–20% of the model-simulated CH4 increase due to surface emissions. Between 2010 and 2016, the ensemble of simulations showed that OH changes could lead to a CH4 mixing ratio uncertainty of > 30 ppbv. Over the full 2000–2016 time period, using a common stateof- the-art but nonoptimized emission scenario, the impact of [OH] changes tested here can explain up to 54% of the gap between model simulations and observations. This result emphasizes the importance of better representing OH abundance and variations in CH4 forward simulations and emission optimizations performed by atmospheric inversions

    Prison, Poverty & Charity: Medieval to Modern

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    Exhibit in six panels comparing medieval prison, poverty and assistance to incarcerated people in the Middle Ages and today, with specific reference to the work of the Nebraska nonprofit RISE. This banner was created in Hist 4910 and was done as a collective class project. Additional banners and a PDF of all banners can be found in the additional files.https://digitalcommons.unomaha.edu/tellallthetruthspring2024/1000/thumbnail.jp

    Characterization of SARS-CoV-2 nucleocapsid protein reveals multiple functional consequences of the C-terminal domain

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    Nucleocapsid (N) encoded by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) plays key roles in the replication cycle and is a critical serological marker. Here, we characterize essential biochemical properties of N and describe the utility of these insights in serological studies. We define N domains important for oligomerization and RNA binding and show that N oligomerization provides a high-affinity RNA-binding platform. We also map the RNA-binding interface, showing protection in the N-terminal domain and linker region. In addition, phosphorylation causes reduction of RNA binding and redistribution of N from liquid droplets to loose coils, showing how N-RNA accessibility and assembly may be regulated by phosphorylation. Finally, we find that the C-terminal domain of N is the most immunogenic, based on antibody binding to patient samples. Together, we provide a biochemical description of SARS-CoV-2 N and highlight the value of using N domains as highly specific and sensitive diagnostic markers

    Discontinuation of RAAS Inhibition in Children with Advanced CKD

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    Background and objectives Although renin-angiotensin-aldosterone system inhibition (RAASi) is a cornerstone in the treatment of children with CKD, it is sometimes discontinued when kidney function declines. We studied the reasons of RAASi discontinuation and associations between RAASi discontinuation and important risk markers of CKD progression and on eGFR decline in the Cardiovascular Comorbidity in Children with CKD study. Design, setting, participants,& measurements In this study, 69 children with CKD(67% male, mean age 13.7 years, mean eGFR 27 ml/min per 1.73m(2)) who discontinued RAASi during prospective follow-up were included. Initial change in BP, albuminuria, and potassium after discontinuation were assessed (median time 6 months). Rate of eGFR decline (eGFR slope) during a median of 1.9 years before and 1.2 years after discontinuation were estimated using linear mixed effects modeling. Results Physician-reported reasons for RAASi discontinuation were increase in serum creatinine, hyperkalemia, and symptomatic hypotension. After discontinuation of RAASi, BP and albuminuria increased, whereas potassium decreased. eGFR declined more rapidly after discontinuation of RAASi (23.9 ml/min per 1.73m2 per year; 95% confidence interval, 25.1 to 22.6) compared with the slope during RAASi treatment (21.5 ml/min per 1.73 m(2) per year; 95% confidence interval, 22.4 to 20.6; P=0.005). In contrast, no change in eGFR slope was observed in a matched control cohort of patients in whom RAASi was continued. Conclusions Discontinuation of RAASi in children with CKD is associated with an acceleration of kidney function decline, even in advanced CKD
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