463 research outputs found

    Friction and Wear Performance Evaluation of Bio-Lubricants and DLC Coatings on Cam/Tappet Interface of Internal Combustion Engines.

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    The environmental concerns associated with artificially formulated engine oils have forced a shift towards bio-based lubricants. The deposition of hard coatings on engine components and migrating to environmentally friendly green lubricants can help in this regard. Chemically modified forms of vegetable oils, with better low-temperature characteristics and enhanced thermo-oxidative stability, are suitable substitutes to conventional lubricant base oils. The research presented in this manuscript was undertaken to experimentally investigate the wear and friction performance of a possible future generation of an environmentally friendly bio-based lubricant as a potential replacement for conventional engine lubricants. In order to quantify the tribological benefits which can be gained by the deposition of DLC coatings, (an (a-C:H) hydrogenated DLC coating and an (a-C:H:W) tungsten-doped DLC coating) were applied on the cam/tappet interface of a direct acting valve train assembly of an internal combustion engine. The tribological correlation between DLC-coated engine components, lubricant base oils and lubricant additives have been thoroughly investigated in this study using actual engine operating conditions. Two additive-free base oils (polyalphaolefines (PAO) and chemically-modified palm oil (TMP)) and two multi-additive-containing lubricants were used in this investigation. Real-time drive torque was measured to determine the friction force, detailed post-test analysis was performed, which involved the use of a specialized jig to measure camlobe wear. An optical profilometer was used to measure the wear on the tappet, high-resolution scanning electron microscopy was employed to study the wear mechanism and energy-dispersive X-ray spectroscopy was performed on the tested samples to qualitatively access the degradation of the coating. When using additive-free TMP, a low friction coefficient was observed for the cam/tappet interface. The presence of additives further improved the friction characteristics of TMP, resulting in reduced average friction torque values. A tremendous enhancement in wear performance was recorded with a-C:H-coated parts and the coating was able to withstand the test conditions with little or no delamination

    Public Place Smoke-Free Regulations, Secondhand Smoke Exposure and Related Beliefs, Awareness, Attitudes, and Practices among Chinese Urban Residents

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    Objective: To evaluate the association between smoke-free regulations in public places and secondhand smoke exposure and related beliefs, awareness, attitudes, and behavior among urban residents in China. Methods: We selected one city (Hangzhou) as the intervention city and another (Jiaxing) as the comparison. A structured self-administered questionnaire was used for data collection, and implemented at two time points across a 20-month interval. Both unadjusted and adjusted logistic methods were considered in analyses. Multiple regression procedures were performed in examining variation between final and baseline measures. Results: Smoke-free regulations in the intervention city were associated with a significant decline in personal secondhand smoke exposure in government buildings, buses or taxis, and restaurants, but there was no change in such exposure in healthcare facilities and schools. In terms of personal smoking beliefs, awareness, attitudes, and practices, the only significant change was in giving quitting advice to proximal family members. Conclusions: There was a statistically significant association between implementation of smoke-free regulations in a city and inhibition of secondhand tobacco smoking exposure in public places. However, any such impact was limited. Effective tobacco control in China will require a combination of strong public health education and enforcement of regulation

    Assessment of tobacco control advocacy behavioural capacity among students at schools of public health in China

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    OBJECTIVES. To evaluate student tobacco control advocacy behavioural capacity using longitudinal trace data. METHODS. A tobacco control advocacy curriculum was developed and implemented at schools of public health (SPH) or departments of public health in seven universities in China. Participants comprised undergraduate students studying the public health curriculum in these 13 Universities. A standardised assessment tool was used to evaluate their tobacco control advocacy behavioural capacity. Repeated measures analysis of variance, paired t tests and paired ?2 tests were used to determine differences between dependent variables across time. Multivariate analysis of variance (MANOVA) and multivariate logistic regression were used to assess treatment effects between intervention and control sites. RESULTS. Respective totals of 426 students in the intervention group and 338 in the control group were available for the evaluation. Approximately 90% of respondents were aged 21 years or older and 56% were women. Findings show that the capacity building program significantly improved public health student advocacy behavioural capacity, including advocacy attitude, interest, motivation and anti-secondhand smoke behaviours. The curriculum did not impact student smoking behaviour. CONCLUSIONS. This study provides sufficient evidence to support the implementation of tobacco control advocacy training at Chinese schools of public health.International Union Against Tuberculosis and Lung Disease(U-China-1-15

    Method for the fast determination of bromate, nitrate and nitrite by ultra performance liquid chromatography–mass spectrometry and their monitoring in Saudi Arabian drinking water with chemometric data treatment

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    A rapid, sensitive and precise method for the determination of bromate (BrO3(-)), nitrate (NO3(-)) and nitrite (NO2(-)) in drinking water was developed with Ultra performance Liquid Chromatography-Mass Spectrometry (UPLC-ESI/MS). The elution of BrO3(-), NO3(-) and NO2(-) was attained in less than two minutes in a reverse phase column. Quality parameters of the method were established; run-to-run and day-to-day precisions were <3% when analysing standards at 10”gL(-1). The limit of detection was 0.04”g NO2(-)L(-1) and 0.03”gL(-1) for both NO3(-)and BrO3(-). The developed UPLC-ESI/MS method was used to quantify these anions in metropolitan water from Saudi Arabia (Jeddah, Dammam and Riyadh areas) and commercial bottled water (from well or unknown source) after mere filtration steps. The quantified levels of NO3(-) were not found to pose a risk. In contrast, BrO3(-) was found above the maximum contaminant level established by the US Environmental Protection Agency in 25% and 33% of the bottled and metropolitan waters, respectively. NO2(-) was found at higher concentrations than the aforementioned limits in 70% and 92% of the bottled and metropolitan water samples, respectively. Therefore, remediation measures or improvements in the disinfection treatments are required. The concentrations of BrO3(-), NO3(-) and NO2(-) were mapped with Principal Component analysis (PCA), which differentiated metropolitan water from bottled water through the concentrations of BrO3(-) and NO3(-) mainly. Furthermore, it was possible to discriminate between well water; blend of well water and desalinated water; and desalinated water. The point or source (region) was found to not be distinctive

    Integration of metal organic frameworks with enzymes as multifunctional solids for cascade catalysis

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    [EN] Enzymes exhibit a large degree of compatibility with metal-organic frameworks (MOFs) which allows the development of multicomponent catalysts consisting of enzymes adsorbed or occluded by MOFs. The combination of enzymes and MOFs in a multicomponent catalyst can be used to promote cascade reactions in which two or more individual reactions are performed in a single step. Cascade reactions take place due to the cooperation of active sites present on the MOF with the enzyme. A survey of the available data establishes that often an enzyme undergoes stabilization by association with a MOF and the system exhibits notable recyclability. In addition, the existence of synergism is observed as a consequence of the close proximity of all the required active sites in the multicomponent catalyst. After an introductory section describing the specific features and properties of enzyme-MOF assemblies, the main part of the present review focuses on the description of the cascade reactions that have been reported with commercial enzymes associated with MOFs, paying special attention to the advantages derived from the multicomponent catalyst. Related to the catalytic activity to metabolize glucose, generating reactive oxygen species (ROS) and decreasing the solution pH, an independent section describes the recent use of enzyme-MOF catalysts in cancer therapy. The last paragraphs summarize the current state of the art and provide our view on future developments in this field.Financial support by the Spanish Ministry of Science and Innovation (Severo Ochoa and CTQ2018-980237-CO2-1) and Generalitat Valenciana (Prometeo 2017-083) is gratefully acknowledged. A. D. thanks the University Grants Commission (UGC), New Delhi, for the award of an Assistant Professorship under its Faculty Recharge Programme. A. D. also thanks the Department of Science and Technology, India, for the financial support through Extra Mural Research Funding (EMR/2016/006500).Dhakshinamoorthy, A.; Asiri, AM.; GarcĂ­a GĂłmez, H. (2020). Integration of metal organic frameworks with enzymes as multifunctional solids for cascade catalysis. Dalton Transactions. 49(32):11059-11072. https://doi.org/10.1039/d0dt02045aS11059110724932Koshland, D. E. (1958). Application of a Theory of Enzyme Specificity to Protein Synthesis. Proceedings of the National Academy of Sciences, 44(2), 98-104. doi:10.1073/pnas.44.2.98Stanton, R. V., PerĂ€kylĂ€, M., Bakowies, D., & Kollman, P. A. (1998). Combined ab initio and Free Energy Calculations To Study Reactions in Enzymes and Solution:  Amide Hydrolysis in Trypsin and Aqueous Solution. Journal of the American Chemical Society, 120(14), 3448-3457. doi:10.1021/ja972723xKuhn, B., & Kollman, P. A. (2000). QM−FE and Molecular Dynamics Calculations on Catechol O-Methyltransferase:  Free Energy of Activation in the Enzyme and in Aqueous Solution and Regioselectivity of the Enzyme-Catalyzed Reaction. Journal of the American Chemical Society, 122(11), 2586-2596. doi:10.1021/ja992218vBruice, T. C., & Lightstone, F. C. (1998). Ground State and Transition State Contributions to the Rates of Intramolecular and Enzymatic Reactions. Accounts of Chemical Research, 32(2), 127-136. doi:10.1021/ar960131yTsitkov, S., & Hess, H. (2019). Design Principles for a Compartmentalized Enzyme Cascade Reaction. ACS Catalysis, 9(3), 2432-2439. doi:10.1021/acscatal.8b04419Muschiol, J., Peters, C., Oberleitner, N., Mihovilovic, M. D., Bornscheuer, U. T., & Rudroff, F. (2015). Cascade catalysis – strategies and challenges en route to preparative synthetic biology. Chemical Communications, 51(27), 5798-5811. doi:10.1039/c4cc08752fLiu, Z., Lv, Y., & An, Z. (2017). Enzymatic Cascade Catalysis for the Synthesis of Multiblock and Ultrahigh-Molecular-Weight Polymers with Oxygen Tolerance. Angewandte Chemie International Edition, 56(44), 13852-13856. doi:10.1002/anie.201707993Wang, H., Cheng, L., Ma, S., Ding, L., Zhang, W., Xu, Z., 
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 Hupp, J. T. (2012). Metal–Organic Framework Materials with Ultrahigh Surface Areas: Is the Sky the Limit? Journal of the American Chemical Society, 134(36), 15016-15021. doi:10.1021/ja3055639Martin, R. L., & Haranczyk, M. (2013). Exploring frontiers of high surface area metal–organic frameworks. Chemical Science, 4(4), 1781. doi:10.1039/c3sc00033hHe, Y., Li, B., O’Keeffe, M., & Chen, B. (2014). Multifunctional metal–organic frameworks constructed from meta-benzenedicarboxylate units. Chem. Soc. Rev., 43(16), 5618-5656. doi:10.1039/c4cs00041bYuan, S., Feng, L., Wang, K., Pang, J., Bosch, M., Lollar, C., 
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    Exploring the drivers and barriers to green supply chain management implementation: A study of independent UK restaurants

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    This is an exploratory study into the drivers and barriers faced by independent restaurants when implementing green supply chain management (GSCM) practices. There is a limited evidence in the literature that attempts to explore GSCM implementation practices in the restaurant industry. The study follows a qualitative interviewing and grounded theory approach. Analysis of the results revealed that restaurants experience many of the same drivers and barriers identified in the existing literature with notable exceptions such as the drivers of company ethos and a media focus. Whereas the key barriers emerged from the study are logistics, skepticism, corporate lying and the owner’s financial responsibility. These findings could be indicators of the wider experience of the UK independent restaurant industry. The study contributes to the literature by offering an insight into how the previously unstudied experiences of UK independent restaurants are similar and different to that of the larger restaurant chains and SMEs in other industries

    Family-based factors associated with overweight and obesity among Pakistani primary school children

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    <p>Abstract</p> <p>Background</p> <p>Childhood obesity epidemic is now penetrating the developing countries including Pakistan, especially in the affluent urban population. There is no data on association of family-based factors with overweight and obesity among school-aged children in Pakistan. The study aimed to explore the family-based factors associated with overweight and obesity among Pakistani primary school children.</p> <p>Methods</p> <p>A population-based cross-sectional study was conducted with a representative multistage cluster sample of 1860 children aged five to twelve years in Lahore, Pakistan. Overweight (> +1SD BMI-for-age z-score) and obesity (> +2SD BMI-for-age z-score) were defined using the World Health Organization reference 2007. Chi-square test was used as the test of trend. Linear regression was used to examine the predictive power of independent variables in relation to BMI. Logistic regression was used to quantify the independent predictors of overweight and adjusted odds ratios (aOR) with 95% confidence intervals (CI) were obtained. All regression analyses were controlled for age and gender and statistical significance was considered at P < 0.05.</p> <p>Results</p> <p>Significant family-based correlates of overweight and obesity included higher parental education (P < 0.001), both parents working (P = 0.002), fewer siblings (P < 0.001), fewer persons in child's living room (P < 0.001) and residence in high-income neighborhoods (P < 0.001). Smoking in living place was not associated with overweight and obesity. Higher parental education (P < 0.001) and living in high-income neighborhoods (P < 0.001) showed a significant independent positive association with BMI while greater number of siblings (P = 0.001) and persons in child's living room (P = 0.022) showed a significant independent inverse association. College-level or higher parental education as compared to high school-level or lower parental education (aOR 2.54, 95% CI 1.76-3.67), living in high-income neighborhoods as compared to low-income neighborhoods (aOR 2.13, 95% CI 1.31-3.46) and three or less siblings as compared to more than three siblings (aOR 1.75, 95% CI 1.26-2.42) were significant independent predictors of overweight.</p> <p>Conclusion</p> <p>Family-based factors were significantly associated with overweight and obesity among school-aged children in Pakistan. Higher parental education, living in high-income neighborhoods and fewer siblings were independent predictors of overweight. These findings support the need to design evidence-based child health policy and implement targeted interventions, considering the impact of family-based factors and involving communities.</p
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