1,103 research outputs found
Study on determining stability domains for nonlinear dynamical systems Final report 1 May 1966 - 1 Feb. 1967
Numerical procedure for determining stability domains in nonlinear dynamical system
Study on determining stability domains for nonlinear dynamical systems, II Quarterly progress report, 1 Aug. - 31 Oct. 1966
Stability domain determination for nonlinear dynamical syste
Confinement of chiral molecules in reverse micelles:FT-IR,polarimetric and VCD investigation on the state of dimethyl tartrate in sodium bis(2-ethylhexyl) sulfosuccinate reverse micelles dispersed in carbon tetrachloride
The state of d and l-dimethyl tartrate confined within dry sodium bis(2-ethylhexyl) sulfosuccinate
(AOT) reverse micelles dispersed in CCl4 has been investigated by FT-IR spectroscopy, polarimetry, and
vibrational circular dichroism (VCD). Measurements have been performed at 25 ◦C as a function of the
solubilizate-to-surfactant molar ratio (R) at a fixed AOT concentration (0.158 M). The analysis of experimental
data is consistent with the hypothesis that both enantiomers of dimethyl tartrate are mainly
entrapped in the reverse micelles and located in proximity to the surfactant head-group region. The
formation of this interesting self-organized chiral nanostructure involves some changes of the typical
H-bonding of dimethyl tartrates in the pure solid state or as monomers dispersed in CCl4 attributable to
the establishment of specific solubilizate/surfactant head-group interactions and confinement effects
Improving performance of the hospitalization process by applying the principles of Lean Thinking
Purpose: The goal was to improve the quality of the hospitalization process and the management of patients, allowing the reduction of costs and the minimization of the preoperative Length of Hospital Stay (LOS). Design/methodology/approach: The methodology used to improve the quality of the hospitalization process and patient management was Lean Thinking. Therefore, the Lean tools (Value stream map and Ishikawa diagram) were used to identify waste and inefficiencies, improving the process with the implementation of corrective actions. The data was collected through personal observations, patient interviews, brainstorming and from printed medical records of 151 patients undergoing oral cancer surgery in the period from 2006 to 2018. Findings: The authors identified, through Value Stream Map, waste and inefficiencies during preoperative activities, consequently influencing preoperative LOS, considered the best performance indicator. The main causes were identified through the Ishikawa diagram, allowing reflection on possible solutions. The main corrective action was the introduction of the pre-hospitalization service. A comparative statistical analysis showed the significance of the solutions implemented. The average preoperative LOS decreased from 4.90 to 3.80 days (−22.40%) with a p-value of 0.001. Originality/value: The methodology allowed to highlight the improvement of the patient hospitalization process with the introduction of the pre-hospitalization service. Therefore, by adopting the culture of continuous improvement, the flow of hospitalization was redrawn. The benefits of the solutions implemented are addressed to the patient in terms of lower LOS and greater service satisfaction and to the hospital for lower patient management costs and improved process quality. This article will be useful for those who need examples on how to apply Lean tools in healthcare
Six Sigma Approach for a First Evaluation of a Pharmacological Therapy in Tongue Cancer
Tongue cancers are among the most frequent malignancies in the population and their influence can be affected by many risk factors. Patients undergoing tongue surgery face different complications and can experience a long length of hospital stay (LOS). The aim of this paper is to compare two pharmacological therapies in order to understand which one decreases the LOS. At the University hospital of Naples “Federico II” two antibiotics were employed: Cefazolin plus Clindamycin and Ceftriaxone. Six Sigma methodology was employed to analyse two group of patients treated with these two different antibiotics: 55 patients treated with the antibiotic Cefazolin plus Clindamycin and 66 patients with the antibiotic Ceftriaxone. This is the first time that this methodology is used in order to compare two antibiotics in the oncology field. The results obtained show clearly and with a statistical evidence that patients treated with Ceftriaxone experienced a lower LOS (−28.6% in terms of percentage between medians). Reducing the LOS for patients means limiting the number of complications and, therefore, reducing the hospitalization costs. It would be valuable for both hospital and patients: the former would save money that they could invest in other important care activities; the latter would experience a higher quality of care with fewer complications
Sodium bis-(2-ethylhexyl) sulfosuccinate sepf-aggregation in vacuo: Molecular Dynamics simulation
Molecular dynamics (MD) simulations were conducted for systems in vacuo consisting of n AOT
anions (bis(2-ethylhexyl)sulfosuccinate ions) and n 1 or n Na+ ions up to n = 20. For n = 15,
positively charged systems with Li+, K+, and Cs+ cations were also considered. All systems were
observed to form reverse micelle-like aggregates whose centre is occupied by cations and polar
heads in a very compact solid-like way, while globally the aggregate has the form of an elongated
and rather flat ellipsoid. Various types of statistical analyses were carried out on the systems to
enlighten structural and dynamical properties including gyration radius, atomic pair correlation
functions, atomic B-factor and moment of inertia tensor. For completeness and comparison the
stability of reverse micelle is tested in the case of neutral n = 20 system in CCl4 solution
Current driven rotating kink mode in a plasma column with a non-line-tied free end
First experimental measurements are presented for the kink instability in a
linear plasma column which is insulated from an axial boundary by finite sheath
resistivity. Instability threshold below the classical Kruskal-Shafranov
threshold, axially asymmetric mode structure and rotation are observed. These
are accurately reproduced by a recent kink theory, which includes axial plasma
flow and one end of the plasma column that is free to move due to a
non-line-tied boundary condition.Comment: 4 pages, 6 figure
Endoscopic approach for paranasal sinuses osteomas: Our experience and review of literature
Osteomas are common benign bone tumors of the skull and facial structures involving primarily the cranial vault, mandible, external auditory canal, paranasal sinuses, nasal cavity, and orbit.1,2 These neoplasms are usually asymptomatic and account for 0.43% of tumor in population with an incidental finding on 1% of radiographs and on 3% of computed tomography (CT) scans. [1] These solid nodular sclerotic lesions usually arise from the outer table and are usually < 10 mm; lesions larger than 30 mm in diameter are considered giant tumors.3,4,7 Most of patients with such a diagnosis have few or no symptoms, in general only 10% is symptomatic, in the second to fifth decades of life 5,6. In literature, endoscopic endonasal approaches are mainly indicated for small ethmoidal osteomas without significant orbital or frontal extension7, while large osteomas require Caldwell-Luc surgery8 or other more aggressive approaches25. We report our experience about the treatment of paranasal sinuses osteomas treated endoscopically or by endoscope-assisted Caldwell-Luc approach, achieving total removal of the neoplasms with all the advantages deriving by endoscopic technique such as closer visualization of the anatomy, no damage to the surrounding structures, better cosmetic results, less morbidity and shorter hospitalization17
An Empirical Approach to the Bond Additivity Model in Quantitative Interpretation of Sum Frequency Generation Vibrational Spectra
A complete empirical approach from known Raman and IR spectra is used to make
corrections to the bond additivity model for quantitative interpretation of Sum
Frequency generation Vibrational Spectra (SFG-VS) from molecular interfaces.
This empirical correction successfully addresses the failures of the simple
bond additivity model. This empirical approach not only provides new
understandings of the effectiveness and limitations of the bond additivity
model, but also provides a practical roadmap for its application in SFG-VS
studies of molecular interfaces
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