The Effects of Massage Therapy by the Patients Relative on Vital Signs of Males Admitted in Critical Care Unit

Background: Changes in vital signs may affect the myocardial oxygen demand. Massage therapy has been used in intensive care units to relive patients’ physical and psychological problems. In all of the studies massaging has been done by a nurse and the patients’ family did not have any role. Objectives: The present study aimed to examine the effects of massage therapy by patient’s relative on vital signs of patients with acute coronary syndrome and acute myocardial infarction. Patients and Methods: A randomized controlled trial was conducted on 60 male patients hospitalized in coronary care units. In the intervention group, massage therapy was done by one of the patient’s male relatives on the third day of admission. The control group only received the routine care. Vital signs were recorded before and after the massage therapy session. SPSS 11.5 software was employed to analyze data using qui-square, Fischer exact test, independent t-test, paired t-test and descriptive statistics. Results: The pre intervention mean of systolic blood pressure of the intervention group were 126.36 ± 16.80 and changed to 121.70 ± 13.31 after the massage therapy session (P = 0.021). The mean pulse rate of the intervention group was 79.46 ± 10.41 and reached 69.30 ± 9.47 after the intervention (P = 0.001). The mean respiration rate of the intervention group also decreased after massage (P = 0.001). No significant changes were observed in diastolic blood pressure and temperature of the intervention group. No significant changes were observed in vital signs of the control group either. Conclusions: Massage therapy by the patients’ relative, decreased systolic blood pressure, pulse and respiration rates of patients admitted in critical care Unite (CCU). Because of the useful effects of those changes, it can be recommended that massage therapy by a member of the patient’s family be used to balance vital signs of patients admitted in CCU. This study was registered at Iranian Registry of Clinical Trials (IRCT). The registration number of the study is IRCT201112048296N

On rr-Simple kk-Path

An $r$-simple $k$-path is a {path} in the graph of length $k$ that passes through each vertex at most $r$ times. The $r$-SIMPLE $k$-PATH problem, given a graph $G$ as input, asks whether there exists an $r$-simple $k$-path in $G$. We first show that this problem is NP-Complete. We then show that there is a graph $G$ that contains an $r$-simple $k$-path and no simple path of length greater than $4\log k/\log r$. So this, in a sense, motivates this problem especially when one's goal is to find a short path that visits many vertices in the graph while bounding the number of visits at each vertex. We then give a randomized algorithm that runs in time $$\mathrm{poly}(n)\cdot 2^{O( k\cdot \log r/r)}$$ that solves the $r$-SIMPLE $k$-PATH on a graph with $n$ vertices with one-sided error. We also show that a randomized algorithm with running time $\mathrm{poly}(n)\cdot 2^{(c/2)k/ r}$ with $c<1$ gives a randomized algorithm with running time \poly(n)\cdot 2^{cn} for the Hamiltonian path problem in a directed graph - an outstanding open problem. So in a sense our algorithm is optimal up to an $O(\log r)$ factor

Is it cheating or learning the craft of writing? Using Turnitin to help students avoid plagiarism

Plagiarism is a growing problem for universities, many of which are turning to software detection for help in detecting and dealing with it. This paper explores issues around plagiarism and reports on a study of the use of Turnitin in a new university. The purpose of the study was to inform the senior management team about the plagiarism policy and the use of Turnitin. The study found that staff and students largely understood the university’s policy and Turnitin’s place within it, and were very supportive of the use of Turnitin in originality checking. Students who had not used Turnitin were generally keen to do so. The recommendation to the senior management team, which was implemented, was that the use of Turnitin for originality checking should be made compulsory where possible - at the time of the study the use of Turnitin was at the discretion of programme directors. A further aim of the study was to contribute to the sector’s body of knowledge. Prevention of plagiarism through education is a theme identified by Badge and Scott (2009) who conclude an area lacking in research is "investigation of the impact of these tools on staff teaching practices". Although a number of recent studies have considered educational use of Turnitin they focus on individual programmes or subject areas rather than institutions as a whole and the relationship with policy

Role of dendrimers in advanced drug delivery and biomedical applications: a review

Aim: Dendrimers dendritic structural design holds vast promises, predominantly for drug delivery, owing to their unique properties. Dendritic architecture is widespread topology found in nature and offers development of specific properties of chemical substances. Dendrimers are an ideal delivery vehicle candidate for open study of the effects of polymer size, charge, and composition on biologically relevant properties such as lipid bilayer interactions, cytotoxicity, bio-distribution, internalization, blood plasma retention time, and filtration. This article reviews role of dendrimers in advanced drug delivery and biomedical applications. Key Words: dendrimers, drug delivery vehicle, lipid bilayer interactions, dendritic architecture

Dark Matter Spin-Dependent Limits for WIMP Interactions on 19-F by PICASSO

The PICASSO experiment at SNOLAB reports new results for spin-dependent WIMP interactions on $^{19}$F using the superheated droplet technique. A new generation of detectors and new features which enable background discrimination via the rejection of non-particle induced events are described. First results are presented for a subset of two detectors with target masses of $^{19}$F of 65 g and 69 g respectively and a total exposure of 13.75 $\pm$ 0.48 kgd. No dark matter signal was found and for WIMP masses around 24 GeV/c$^2$ new limits have been obtained on the spin-dependent cross section on $^{19}$F of $\sigma_F$ = 13.9 pb (90% C.L.) which can be converted into cross section limits on protons and neutrons of $\sigma_p$ = 0.16 pb and $\sigma_n$ = 2.60 pb respectively (90% C.L). The obtained limits on protons restrict recent interpretations of the DAMA/LIBRA annual modulations in terms of spin-dependent interactions.Comment: Revised version, accepted for publication in Phys. Lett. B, 20 pages, 7 figure

Addressing and Inspiring Vaccine Confidence in Black, Indigenous, and People of Color During the Coronavirus Disease 2019 Pandemic

During the coronavirus disease 2019 (COVID-19) pandemic, we have witnessed profound health inequities suffered by Black, Indigenous, and People of Color (BIPOC). These manifested as differential access to testing early in the pandemic, rates of severe disease and death 2-3 times higher than white Americans, and, now, significantly lower vaccine uptake compared with their share of the population affected by COVID-19. This article explores the impact of these COVID-19 inequities (and the underlying cause, structural racism) on vaccine acceptance in BIPOC populations, ways to establish trustworthiness of healthcare institutions, increase vaccine access for BIPOC communities, and inspire confidence in COVID-19 vaccines

Placing the library at the heart of plagiarism prevention: The University of Bradford experience.

yesPlagiarism is a vexed issue for Higher Education, affecting student transition, retention and attainment. This paper reports on two initiatives from the University of Bradford library aimed at reducing student plagiarism. The first initiative is an intensive course for students who have contravened plagiarism regulations. The second course introduces new students to the concepts surrounding plagiarism with the aim to prevent plagiarism breaches. Since the Plagiarism Avoidance for New Students course was introduced there has been a significant drop in students referred to the disciplinary programme. This paper discusses the background to both courses and the challenges of implementation

Ultra-High Energy Cosmic Ray Probes of Large Scale Structure and Magnetic Fields

We study signatures of a structured universe in the multi-pole moments, auto-correlation function, and cluster statistics of ultra-high energy cosmic rays above 10^19 eV. We compare scenarios where the sources are distributed homogeneously or according to the baryon density distribution obtained from a cosmological large scale structure simulation. The influence of extragalactic magnetic fields is studied by comparing the case of negligible fields with fields expected to be produced along large scale shocks with a maximal strength consistent with observations. We confirm that strongly magnetized observers would predict considerable anisotropy on large scales, which is already in conflict with current data. In the best fit scenario only the sources are strongly magnetized, although deflection can still be considerable, of order 20 degrees up to 10^20 eV, and a pronounced GZK cutoff is predicted. We then discuss signatures for future large scale full-sky detectors such as the Pierre Auger and EUSO projects. Auto-correlations are sensitive to the source density only if magnetic fields do not significantly affect propagation. In contrast, for a weakly magnetized observer, degree scale auto-correlations below a certain level indicate magnetized discrete sources. It may be difficult even for next generation experiments to distinguish between structured and unstructured source distributions.Comment: 17 revtex pages, 29 ps figures, published version with minor changes, see http://link.aps.org/abstract/PRD/v70/e04300

Deaths Attributed to Respiratory Syncytial Virus in Young Children in High-Mortality Rate Settings: Report from Child Health and Mortality Prevention Surveillance (CHAMPS).

BACKGROUND: Lower respiratory tract infections are a leading cause of death in young children, but few studies have collected the specimens needed to define the role of specific causes. The Child Health and Mortality Prevention Surveillance (CHAMPS) platform aims to investigate causes of death in children aged <5 years in high-mortality rate settings, using postmortem minimally invasive tissue sampling and other advanced diagnostic techniques. We examined findings for deaths identified in CHAMPS sites in 7 countries in sub-Saharan Africa and south Asia to evaluate the role of respiratory syncytial virus (RSV). METHODS: We included deaths that occurred between December 2016 and December 2019. Panels determined causes of deaths by reviewing all available data including pathological results from minimally invasive tissue sampling, polymerase chain reaction screening for multiple infectious pathogens in lung tissue, nasopharyngeal swab, blood, and cerebrospinal fluid samples, clinical information from medical records, and verbal autopsies. RESULTS: We evaluated 1213 deaths, including 695 in neonates (aged <28 days), 283 in infants (28 days to <12 months), and 235 in children (12-59 months). RSV was detected in postmortem specimens in 67 of 1213 deaths (5.5%); in 24 deaths (2.0% of total), RSV was determined to be a cause of death, and it contributed to 5 other deaths. Younger infants (28 days to <6 months of age) accounted for half of all deaths attributed to RSV; 6.5% of all deaths in younger infants were attributed to RSV. RSV was the underlying and only cause in 4 deaths; the remainder (n = 20) had a median of 2 (range, 1-5) other conditions in the causal chain. Birth defects (n = 8) and infections with other pathogens (n = 17) were common comorbid conditions. CONCLUSIONS: RSV is an important cause of child deaths, particularly in young infants. These findings add to the substantial body of literature calling for better treatment and prevention options for RSV in high-mortality rate settings