183 research outputs found
Random Wavelet Series: Theory and Applications
Random Wavelet Series form a class of random processes with multifractal
properties. We give three applications of this construction. First, we
synthesize a random function having any given spectrum of singularities
satisfying some conditions (but including non-concave spectra). Second, these
processes provide examples where the multifractal spectrum coincides with the
spectrum of large deviations, and we show how to recover it numerically.
Finally, particular cases of these processes satisfy a generalized
selfsimilarity relation proposed in the theory of fully developed turbulence.Comment: To appear in Annales Math\'ematiques Blaise Pasca
Applied geophysics in archaeological prospecting at sites of Authumes (Saône-et-Loire) and Mirebeau (Côte-d’Or) (Bourgogne, Eastern France)
Authumes « Le Tertre » (Saône-et-Loire, Bourgogne) The most visible part of the archaeological site of Authumes (Burgundy, Eastern France) is the top of an escarpment which forms the limit separating the Bressan plateau from the floodplain of the Doubs River. The importance and interest of the site are directly connected to the presence of archaeological material abounding on the ground. Numerous varied artefacts such as ceramic, architectural tiles, cut stones, can be found in a band (approx..
Antibacterial Resistance, Wayampis Amerindians, French Guyana
Drug resistance in fecal bacteria was high in Wayampis Amerindians who did not take antibacterial agents and were not hospitalized for 1 year. In the Wayampis Amerindians, an isolated traditional community in French Guyana, antibacterial use was 0.64 treatments per person per year. Hospitalization rate was 6.1% per year. Antibacterial drug–resistant bacteria can spread in persons who are not taking antibacterial agents
TACI, unlike BAFF-R, is solely activated by oligomeric BAFF and APRIL to support survival of activated B cells and plasmablasts.
The cytokine BAFF binds to the receptors TACI, BCMA, and BAFF-R on B cells, whereas APRIL binds to TACI and BCMA only. The signaling properties of soluble trimeric BAFF (BAFF 3-mer) were compared with those of higher-order BAFF oligomers. All forms of BAFF bound BAFF-R and TACI, and elicited BAFF-R-dependent signals in primary B cells. In contrast, signaling through TACI in mature B cells or plasmablasts was only achieved by higher-order BAFF and APRIL oligomers, all of which were also po-tent activators of a multimerization-dependent reporter signaling pathway. These results indicate that, although BAFF-R and TACI can provide B cells with similar signals, only BAFF-R, but not TACI, can respond to soluble BAFF 3-mer, which is the main form of BAFF found in circulation. BAFF 60-mer, an efficient TACI agonist, was also detected in plasma of BAFF transgenic and nontransgenic mice and was more than 100-fold more active than BAFF 3-mer for the activation of multimerization-dependent signals. TACI supported survival of activated B cells and plasmablasts in vitro, providing a rational basis to explain the immunoglobulin deficiency reported in TACI-deficient persons
Applied geophysics in archaeological prospecting at sites of Authumes (Saône-et-Loire) and Mirebeau (Côte-d’Or) (Bourgogne, Eastern France)
Authumes « Le Tertre » (Saône-et-Loire, Bourgogne) The most visible part of the archaeological site of Authumes (Burgundy, Eastern France) is the top of an escarpment which forms the limit separating the Bressan plateau from the floodplain of the Doubs River. The importance and interest of the site are directly connected to the presence of archaeological material abounding on the ground. Numerous varied artefacts such as ceramic, architectural tiles, cut stones, can be found in a band (approx..
Using paired serology and surveillance data to quantify dengue transmission and control during a large outbreak in Fiji.
Dengue is a major health burden, but it can be challenging to examine transmission and evaluate control measures because outbreaks depend on multiple factors, including human population structure, prior immunity and climate. We combined population-representative paired sera collected before and after the 2013/14 dengue-3 outbreak in Fiji with surveillance data to determine how such factors influence transmission and control in island settings. Our results suggested the 10-19 year-old age group had the highest risk of infection, but we did not find strong evidence that other demographic or environmental risk factors were linked to seroconversion. A mathematical model jointly fitted to surveillance and serological data suggested that herd immunity and seasonally varying transmission could not explain observed dynamics. However, the model showed evidence of an additional reduction in transmission coinciding with a vector clean-up campaign, which may have contributed to the decline in cases in the later stages of the outbreak
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