Heart Rate Variability during Plateau Waves of Intracranial Pressure: a pilot descriptive study

This study aims to describe heart rate variability during the first episode of plateau waves of intracranial pressure (ICP) in Traumatic Brain Injury (TBI) in order to characterize and identify at bedside this cerebrovascular phenomenon. The general behavior of the heart rate variability (HRV) spectral measures expressed in the medians across patients is concordant with an increased HRV in the latter part of the baseline and plateau wave, followed by a decrease after the event and a new increase during the recovery. In low and high frequency bands the same increase is more marked in the parametric analysis. Interpretation of HRV may help clinicians to better identify the plateau waves and allow earlier management

Processing and classification of biological images: Application to histology

This article deals with a histological problem by using image processing and feature extraction in images of renal tissues of rats and their classification through various methods such as: Bayesian inference, decision trees and support vector machines

Arsenite oxidase in complex with antimonite and arsenite oxyanions - insights into the catalytic mechanism

Arsenic contamination of groundwater is among one of the biggest health threats affecting millions of people in the world. There is an urgent need for efficient arsenic biosensors where the use of arsenic metabolizing enzymes can be explored. In this work we have solved the crystal structures of four complexes of arsenite oxidase (Aio) obtained in complex with arsenic and antimony oxyanions and the structures determined correspond to intermediate states of the enzymatic mechanism. These structural data were complemented with DFT calculations providing a unique view of the molybdenum active site at different time points that, together with mutagenesis data, enabled to clarify the enzymatic mechanism and the molecular determinants for the oxidation of As(III) to the less toxic As(V) species

Minimal flavour violation extensions of the seesaw

We analyze the most natural formulations of the minimal lepton flavour violation hypothesis compatible with a type-I seesaw structure with three heavy singlet neutrinos N, and satisfying the requirement of being predictive, in the sense that all LFV effects can be expressed in terms of low energy observables. We find a new interesting realization based on the flavour group $SU(3)_e\times SU(3)_{\ell+N}$ (being $e$ and $\ell$ respectively the SU(2) singlet and doublet leptons). An intriguing feature of this realization is that, in the normal hierarchy scenario for neutrino masses, it allows for sizeable enhancements of $\mu \to e$ transitions with respect to LFV processes involving the $\tau$ lepton. We also discuss how the symmetries of the type-I seesaw allow for a strong suppression of the N mass scale with respect to the scale of lepton number breaking, without implying a similar suppression for possible mechanisms of N productionComment: 14 pages, 6 figure

Mollusca from a species-rich deep-water Leptometra community in the Alboran Sea

Postprint1,006

Diagn?stico del uso del fideicomiso como herramienta eficiente para promover proyectos de vivienda social masiva

La presente investigaci?n se propone los siguientes objetivos: - Proponer alternativas para mitigar el d?ficit habitacional a trav?s de lineamientos y pol?ticas de vivienda social masiva mejorando y ampliando los esquemas de financiamiento para los proyectos de vivienda social masiva. - Analizar la normativa peruana, identificar posibles deficiencias y proponer el uso de la figura del fideicomiso como mecanismo de acceso a la vivienda social para las mayor?as. - Proponer a trav?s del fideicomiso la construcci?n de viviendas para disminuir la autoconstrucci?n, las invasiones que permitan construcciones a menos costos, en zonas seguras y asegurar la calidad de vida de los pobladores de menos recursos

Plan de negocios para la implementaci?n de una instituci?n de microcr?ditos en la ciudad de Piura

La presente tesis propone implementar una casa de pr?stamos en la ciudad de Piura para satisfacer la demanda de pr?stamos del microempresario, espec?ficamente ubicado en los distritos de Piura, Castilla, Catacaos y 26 de Octubre. La instituci?n de microcr?ditos propuesta plantea una oferta accesible tanto para el empresario formal como informal, con tasas de inter?s promedio a las casas de pr?stamo e inferior al prestamista informal cuya tasa de inter?s puede llegar hasta 20% mensual. La instituci?n propuesta se diferencia de las actuales ofertas de entidades no financieras en lo que respecta a la calidad de servicio y en cuando introduce dentro de sus procesos la tecnolog?a a trav?s de una aplicaci?n que permitir? ingresar una solicitud de pr?stamo en el local del cliente, hacer la cobranza y recibir las aprobaciones de desembolsos en campo sincroniz?ndose con el software que se emplea en oficina. La casa de pr?stamos propuesta se alinear? con las regulaciones estipuladas por la Superintendencia de Banca, Seguros y AFP (SBS) a trav?s del registro de casas de pr?stamo, lo que le da transparencia en sus operaciones y la constituyeen una entidad formal de pr?stamos