Correction of zinc deficiency in children with type 1 diabetes mellitus

Scientific supervisor: N.V. GluschenkoThe most important in the pathogenesis of diabetes mellitus type 1 (DM-1) among trace elements has zinc (Zn). With the participation of Zn ions is an allocation of insulin from β-cells of Langerhans islands, the inclusion of insulin to transport complex, inhibition of insulinazy. Therefore, zinc deficiency can be considered as one of the factors of development and labile course of DM-1 in children. When you are citing the document, use the following link http://essuir.sumdu.edu.ua/handle/123456789/2749

Ionic liquid-assisted hydrothermal synthesis of a biocompatible filler for photo-curable dental composite : from theory to experiment

Nanostructured hydroxyapatite (HA) is a new class of biocompatible fillers which has been recently utilized in bio hybrid materials by virtue of its excellent tissue bioactivity and biocompatibility. However, the need for higher thermal stability, solubility, surface bioactivity, radiopacity, and remineralization ability suggests a divalent cation substitution of HA for use in light curable dental restorative composites. In this work, structural and optical properties of Sr-doped hydroxyapatite were studied using first-principle calculations based on density functional theory (DFT). Next, Sr-doped hydroxyapatite (HA) was prepared via a new ionic liquid-assisted hydrothermal (ILH) route. Samples were characterized using X-ray diffraction (XRD), scanning electron microscopy (SEM)/energy dispersive spectroscopy (EDS), Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM), dynamic light scattering (DLS), Brunauer-Emmett-Teller (BET) surface area analysis, and cell viability. The obtained experimental data showed that the nucleation and crystal growth process controlled by [BMIM]Br molecules results in uniform products with small and regular particles and high specific surface areas. Finally, cytotoxicity tests showed that the as-prepared Sr-doped HA nanoparticles have good biocompatibility (â¥91%), confirming their potential for use in photo-curable dental restorative composites

Pengaruh Budaya Organisasi, Kompetensi Dan Disiplin Kerja Terhadap Kinerja Pegawai Dengan Kepuasan Kerja Sebagai Mediasi (Studi Kasus Dinas Pemberdayaan Masyarakat Kabupaten Pasaman)

Penelitian ini bertujuan untuk menganalisis pengaruh budaya organisasi, kompetensi dan disiplin kerja terhadap kinerja pegawai dengan kepuasan kerja sebagai mediasi pada Dinas Pemberdayaan Masyarakat Kabupaten Pasaman. Penelitian ini dilatarbelakangi oleh kinerja pegawai yang masih tidak stabil dan masih dapat ditingkatkan lagi, hal ini dikarenakan budaya organisasi dan kompetensi pegawai yang masih rendah, dan tingkat kepuasan kerja pegawai yang masih belum belum terpenuhi. Jenis penelitian menggunakan pendekatan kuantitatif dengan menggunakan pendekatan Partial Least Square dengan model persamaan Structural Equation Modeling. Teknik pengumpulan data dengan kuesioner dan observasi. Responden penelitian berjumlah 57 orang pegawai Dinas Pemberdayaan Masyarakat Kabupaten Pasaman. Metode penarikan sampel mengunakan metode total sampling Pengujian hipotesis dihitung dengan program SmartPLS. Dari hasil penelitian ini ditemukan bahwa pengaruh langsung budaya organisasi berpengaruh positif dan signifikan terhadap kepuasan kerja, kompetensi dan disiplin kerja tidak berpengaruh positif dan signifikan terhadap kepuasan kerja, kepuasan kerja dan kompetensi berpengaruh positif dan signifikan terhadap kinerja, budaya organisasi dan disiplin kerja tidak berpengaruh positif dan signifikan terhadap kinerja. Pengaruh tidak langsung kepuasan kerja sebagai mediasi berpengaruh antara budaya organisasi dan kinerja serta berpengaruh antara disiplin kerja dan kinerja. Namun kepuasan kerja sebagai mediasi tidak berpengaruh antara kompetensi dan kinerja pegawai Dinas Pemberdayaan Masyarakat Kabupaten Pasaman. Kata Kunci:          budaya organisasi, kompetensi, disiplin kerja, kepuasan kerja, kinerja

Analyse des lisibilités du manuel de français langue étrangère à travers le test de closure

RÉSUMÉ. Cette étude tente d’étudier la lisibilité de manuel de français largement utilisés en Indonésie et à décrire les classes de mots qui influencent sa lisibilité. Cette étude utilise une conception de recherche de méthode mixte avec une approche de conception convergente. Les données ont été obtenues à partir de trois textes pris au hasard dans un manuel de français et analysées en effectuant le test de closure auprès des étudiants du deuxième semestre du programme d'études de français dans une université en Indonésie. Les résultats du test de lisibilité montre qu'aucun texte n'est classé comme élevé ou sans assistance. Cependant, il est déterminé qu'un texte appartient à la catégorie moyenne ou à la lecture pédagogique et à la lecture assistée. Tandis que le reste du texte appartient à la même catégorie, qui est faible ou au niveau de frustration. Il est donc conclu que le niveau de lisibilité de ce manuel peut être considéré comme assez bon. La présente étude a des implications pour les études de la didactique de français langue étrangère, notamment pour l’évaluation des manuels. Mots-clés : français langue étrangère, lisibilité, manuel, test de closure. ABSTRACT. This study attemps to investigate the readability of French language textbook that is widely used in Indonesia and to describe word classes that influence its/the readability. This study employs a mixed method research design with a convergent design approach. The data were obtained from three texts taken randomly from a French textbook, and analyzed by conducting the cloze test to the students of second semester at French study program in one university in Indonesia. The results of the readability test show that none of the text are categorized as high or unassisted. However, one text is determined to be in the medium category or instructional and assisted reading. While, the rest of the text are in the same category, which is low or in frustrasion level. It is therefore concluded that the level of readability of this manual can be considered quite good. The current study has implications to French as a foreign language teaching-learning studies, especially for textbook assessment. Keywords: cloze test, french for foreign language, readibility, textbook

Designing the Prohibitive Model of the Corruption Based on the Islamic Doctrines

The study aimed to design the prohibitive model of the corruption based on the Islamic doctrines. The purposes of the study included designing and testing the model. The research has used the mixed method (qualitative-quantitative) from expletory type. The statistical population (79 people) consisted of the managers of four headquarters of the anti-corruption committee of industry, mine and commerce.  Cochran’s sample size formula demonstrated 65 people.  The researcher-made questionnaire was used to collect the data. The validity of the questionnaire was measured and confirmed by some professors and masters of Islamic sciences and seminary (who have reached the juridical –religious leadership) and the managers of the anti-corruption (who have acted in the field for 10 years). The reliability of the questionnaire has been estimated %77 through Cronbach's Alpha coefficient. To analyze and obtain the final model, the analysis test of the structural equations (PLS software) was used. The results show that the effect of the exaltation on the prohibition of the corruption, of the prohibition on conflict, and of the exaltation on the treatment through the prohibition are 0.694(9.592), 0.431(2.762), 0.692(10.31), respectively. All of them indicate a significant relation. The effect of the moral and spiritual qualities on the solving mechanism, on the controlling mechanism, on the selective - professional mechanism, on the structural mechanism, on the tact, and on the avoidance of the avarice have been evaluated 0.426 (3.922), 0.691 (12.248), 0.690 (11.215), 0.653 (11.825), respectively. Consequently, the factors of the exaltation and avoidance have most effect on the prohibition of the corruption. Keywords: designing a model, prohibition, avoidance, corruption, exaltation, Islamic doctrines

Reconfiguration of Distribution Networks with Presence of DGs to improving the Reliability

In this paper, the network reconfiguration in the presence of distributed generation units with the aim of improving the reliability of the network is studied. For this purpose four reliability parameters in the objective function are considered, which is average energy not supplied system average interruption frequency index, system average interruption duration index and momentary average interruption frequency index. The new method will be normalized objective function. Another suggestion of this paper are considering the different fault rates, locating time of faults type and prioritization of customers based on their importance. This nonlinear problem has optimized by particle swarm optimization (PSO) algorithm

Comparison of Renal Safety of Tenofovir and Telbivudine in Chronic Hepatitis B Patients: A Real World Study in Indonesia

Introduction. Tenofovir disoproxil fumarate (tenofovir) and telbivudine are two available nucleos(t)ide analogue (NA) for the treatment of chronic hepatitis B (CHB) patients. Tenofovir has been known as a nephrotoxic agent in HIV patients, but still controversy in CHB patients. On the other hand, telbivudine had a renal protective effect and increased estimated glomerular filtration rate (eGFR). This studi aimed to address the renal safety of tenofovir and telbivudine in Indonesian patients. Method. A retrospective cohort study design was conducted in CHB patients who prescribed with tenofovir or telbivudine from January 2013 to December 2016. Patients who met the inclusion and exclusion criteria were followed up for one year. The serial evaluation of creatinine serum was collected in week-24 and week-48 after the administration of tenofovir or telbivudine. Results. Among CHB patients, 68 and 62 patients that prescribed with tenofovir or telbivudine, respectively, were enrolled in this study. Serum creatinine level was increased in tenofovir group from 0.88 (SD 0.17) mg/dL at baseline to 0.93 (SD 0.22) mg/dL after 24 weeks (p = 0.02), but creatinine trend to reach plateau after 48 weeks. However, in telbivudine group, serum creatinine level was decreased from 0.85 (SD 0.21) mg/dL at baseline to 0.80 (SD 0.18) mg/dL after 48 weeks (p = 0.003). Conclusion. Tenofovir is associated with the increased of creatinine serum and decreased of eGFR in CHB patients with eGFR ≥60 mL/menit/1,73 m2

The pattern of knowledge sharing in organization with social interaction approach: A case study in the Research Department of National Iranian Oil Engineering and Construction Company

The aim of this study was to provide the pattern of knowledge sharing in organization with social interaction approach. This is an applied, and descriptive-correlational research. The population consisted of senior experts and executive managers of the research department of national Iranian oil engineering and Construction Company. Thirty subjects were selected purposefully who directly involved in the project of knowledge sharing in organization. For data collection, the questionnaire and for data analysis the regression and structural equation modeling were used. The findings indicated that knowledge sharing activities, including sender, recipient, organizational context, and knowledge sharing mechanisms have a significant positive correlation with the function of knowledge sharing; furthermore, the co-existence of knowledge sharing dimensions and their suitability facilitate knowledge sharing in organization. Finally, knowledge sharing is the culture of knowledge-based interactions and appropriate approach for knowledge sharing refers to social interaction approach