3,413 research outputs found

    Arab consumer attitutes towards international marketing as a result of the ongoing Arab Spring : a systematic literature review

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    Paper from the International Conference on Contemporary Marketing Issues (ICCI), Thessaloniki, 13-15 June 2012 The Middle East has been recently and continues to be affected by a phenomenon referred to popularly as the ‘Arab Spring’. The phenomenon appears to have sparked a wave of candidness amongst Arab consumers in a way that hitherto was not apparent. A question as to whether the uprisings are about the pursuit of democracy, political reform or freedom of speech remains to be settled. The purpose of this discussion paper is to ask what effects the Arab Spring may have on marketing theory and practice. To that end, the paper presents the results of a systematic literature review pertaining to marketing in the Middle East. A quantitative bibliometric method of citation analysis is deployed to identify the range of themes that have been previously researched. From this review, the paper identifies the particular relevance of the Arab Spring phenomenon to international marketing theory and practice. Thus, this study makes the first attempt to conceptualize what the Arab Spring means for future international marketing theory and practice and marks the start of a first investigation, and potential beginning of a longitudinal study into the phenomenon as it continues to unfold, grounded firmly in the marketing discipline

    The transition of the self through the Arab Spring in Egypt and Libya

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    This paper builds on Belk's notions of the extended, social, family and dialogic selves in an attempt to explore the transformation of the self during the Arab Spring phenomena. From the perspective of the respondents in Egypt and Libya, this paper provides a reading of how images of self are related to artifacts of consumption, rituals, and symbols and how consumer values are navigated through this difficult landscape. The paper uses a three phase history, happening, and hopes narratives to show that the self in a liminal period of flux is referent to history and hopes and proposes a notion of a transitional self that incorporates this observation of reference to past and future. In particular, the findings suggest that consumption, especially Western consumption can be transcendental during a liminal period of flux and that such revelatory incidents offer an opportunity to access the candid thoughts of consumers

    Symmetry constraints on phonon dispersion in graphene

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    Taking into account the constraints imposed by the lattice symmetry, we calculate the phonon dispersion for graphene with interactions between the first, second, and third nearest neighbors in the framework of the Born--von Karman model. Analytical expressions obtained for the dispersion of the out-of-plane (bending) modes give the nonzero sound velocity. The dispersion of four in-plane modes is determined by coupled equations. Values of the force constants are found in fitting with frequencies at critical points and with elastic constants measured on graphite.Comment: 5 pages, 2 figure

    Metabonomics and Intensive Care

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    This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency medicine 2016. Other selected articles can be found online at http://www.biomedcentral.com/collections/annualupdate2016. Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901

    Are GPs under-investigating older patients presenting with symptoms of ovarian cancer? Observational study using General Practice Research Database

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    Background: Recent studies suggest that older patients in the United Kingdom are not benefiting as much from improvements in cancer treatments as their younger counterparts. We investigate whether this might be partly due to differential referral rates using ovarian cancer as an example. Methods: From the General Practice Research Database (GPRD), we identified all women aged 40–80 years on 1 June 2002 with a Read code for ovarian cancer between 1 June 2002 and 31 May 2007. Using these records, we compared the GPRD incidence of ovarian cancer with rates compiled from the UK cancer registries and investigated the relationship between age and coded investigations for suspected ovarian cancer. Results: The GPRD rates peaked earlier, at 70–74, and were lower than registry rates for nearly all ages particularly for patients over 59. The proportion investigated or referred by the GP decreased significantly with age and delays between first coded symptom and investigation showed a U-shaped distribution by age. Conclusions: GPs appear to be less likely to recognise and to refer patients presenting with ovarian cancer as they get older. If our findings extend to other cancers, lack of or delays in referral to secondary care may partly explain poor UK cancer mortality rates of older people

    Screening of DUB activity and specificity by MALDI-TOF mass spectrometry

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    Deubiquitylases (DUBs) are key regulators of the ubiquitin system which cleave ubiquitin moieties from proteins and polyubiquitin chains. Several DUBs have been implicated in various diseases and are attractive drug targets. We have developed a sensitive and fast assay to quantify in vitro DUB enzyme activity using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. Unlike other current assays, this method uses unmodified substrates, such as diubiquitin topoisomers. By analyzing 42 human DUBs against all diubiquitin topoisomers we provide an extensive characterization of DUB activity and specificity. Our results confirm the high specificity of many members of the OTU and JAMM DUB families and highlight that all USPs tested display low linkage selectivity. We also demonstrate that this assay can be deployed to assess the potency and specificity of DUB inhibitors by profiling 11 compounds against a panel of 32 DUBs

    Inference of population splits and mixtures from genome-wide allele frequency data

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    Many aspects of the historical relationships between populations in a species are reflected in genetic data. Inferring these relationships from genetic data, however, remains a challenging task. In this paper, we present a statistical model for inferring the patterns of population splits and mixtures in multiple populations. In this model, the sampled populations in a species are related to their common ancestor through a graph of ancestral populations. Using genome-wide allele frequency data and a Gaussian approximation to genetic drift, we infer the structure of this graph. We applied this method to a set of 55 human populations and a set of 82 dog breeds and wild canids. In both species, we show that a simple bifurcating tree does not fully describe the data; in contrast, we infer many migration events. While some of the migration events that we find have been detected previously, many have not. For example, in the human data we infer that Cambodians trace approximately 16% of their ancestry to a population ancestral to other extant East Asian populations. In the dog data, we infer that both the boxer and basenji trace a considerable fraction of their ancestry (9% and 25%, respectively) to wolves subsequent to domestication, and that East Asian toy breeds (the Shih Tzu and the Pekingese) result from admixture between modern toy breeds and "ancient" Asian breeds. Software implementing the model described here, called TreeMix, is available at http://treemix.googlecode.comComment: 28 pages, 6 figures in main text. Attached supplement is 22 pages, 15 figures. This is an updated version of the preprint available at http://precedings.nature.com/documents/6956/version/
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