246 research outputs found
Set-up effects of piles in sand tested in the centrifuge
The bearing capacity of piles increases over time. Research has shown that this is caused by an increase in shaft friction combined with a constant or only slightly increasing base capacity. Although there are some ideas on the mechanisms that play a role there is no quantitative model to describe this mechanism. From the literature the shaft friction seems to increase linearly with the logarithm of time. For piles in the field this is proven by load tests performed between 1 until approximately 1000 days after installation. Literature indicates that set-up as a function of time is also present minutes and hours after installation. This allows investigating the set-up mechanisms under controlled conditions in a centrifuge. Therefore two test series have been performed to investigate the set-up for a single pile and a pile group. This paper presents the relevant literature and describes the position of the tests in the on-going research program on piles in The Netherlands. Furthermore, the results will be described and discussed. Time dependency in bearing capacity in sand can be observed in the centrifuge tests, although it is not certain whether some of the increase has not been caused by other mechanisms. It appears that the testing conditions as well as the effects of installation of neighboring piles are of great importance on the time effects
Natural Notation for the Domestic Internet of Things
This study explores the use of natural language to give instructions that
might be interpreted by Internet of Things (IoT) devices in a domestic `smart
home' environment. We start from the proposition that reminders can be
considered as a type of end-user programming, in which the executed actions
might be performed either by an automated agent or by the author of the
reminder. We conducted an experiment in which people wrote sticky notes
specifying future actions in their home. In different conditions, these notes
were addressed to themselves, to others, or to a computer agent.We analyse the
linguistic features and strategies that are used to achieve these tasks,
including the use of graphical resources as an informal visual language. The
findings provide a basis for design guidance related to end-user development
for the Internet of Things.Comment: Proceedings of the 5th International symposium on End-User
Development (IS-EUD), Madrid, Spain, May, 201
Positive psychology of Malaysian students: impacts of engagement, motivation, self-compassion and wellbeing on mental health
Malaysia plays a key role in education of the Asia Pacific, expanding its scholarly output rapidly. However, mental health of Malaysian students is challenging, and their help-seeking is low because of stigma. This study explored the relationships between mental health and positive psychological constructs (academic engagement, motivation, self-compassion, and wellbeing), and evaluated the relative contribution of each positive psychological construct to mental health in Malaysian students. An opportunity sample of 153 students completed the measures regarding these constructs. Correlation, regression, and mediation analyses were conducted. Engagement, amotivation, self-compassion, and wellbeing were associated with, and predicted large variance in mental health. Self-compassion was the strongest independent predictor of mental health among all the positive psychological constructs. Findings can imply the strong links between mental health and positive psychology, especially selfcompassion. Moreover, intervention studies to examine the effects of self-compassion training on mental health of Malaysian students appear to be warranted.N/
Colonoscopic surveillance improves survival after colorectal cancer diagnosis in inflammatory bowel disease
Item does not contain fulltextBACKGROUND: Colonoscopic surveillance provides the best practical means for preventing colorectal cancer (CRC) in inflammatory bowel disease (IBD) patients. Strong evidence for improved survival from surveillance programmes is sparse. METHOD: The aim of this study was to compare tumour stage and survival of IBD patients with CRC who were a part of a surveillance programme with those who were not. A nationwide pathology database (PALGA (pathologisch anatomisch landelijk geautomatiseerd archief)) was consulted to identify IBD patients with CRC treated in all eight university hospitals in The Netherlands over a period of 15 years. Patients were assigned to the surveillance group when they had undergone one or more surveillance colonoscopies before a diagnosis of CRC. Patients who had not undergone surveillance served as controls. Tumour stage and survival were compared between the two groups. RESULTS: A total of 149 patients with IBD-associated CRC were identified. Twenty-three had had colonoscopic surveillance before CRC was discovered. The 5-year CRC-related survival rate of patients in the surveillance group was 100% compared with 74% in the non-surveillance group (P=0.042). In the surveillance group, only one patient died as a consequence of CRC compared with 29 patients in the control group (P=0.047). In addition, more early tumour stages were found in the surveillance group (P=0.004). CONCLUSIONS: These results provide evidence for improved survival from colonoscopic surveillance in IBD patients by detecting CRC at a more favourable tumour stage
Successfully sustaining sex and gender issues in undergraduate medical education: a case study
Ecological divergence of Chaetopteryx rugulosa species complex (Insecta, Trichoptera) linked to climatic niche diversification
Climate is often considered to be an important, but indirect driver of speciation. Indeed, environmental factors may contribute to the formation of biodiversity, but to date this crucial relationship remains largely unexplored. Here we investigate the possible role of climate, geological factors, and biogeographical processes in the formation of a freshwater insect species group, the Chaetopteryx rugulosa species complex (Trichoptera) in the Western Balkans. We used multi-locus DNA sequence data to establish a dated phylogenetic hypothesis for the group. The comparison of the dated phylogeny with the geological history of the Western Balkans shows that lineage formation coincided with major past Earth surface and climatic events in the region. By reconstructing present-day habitat conditions (climate, bedrock geology), we show that the lineages of C. rugulosa species complex have distinct climatic but not bedrock geological niches. Without exception, all splits associated with Pliocene/Pleistocene transition led to independent, parallel split into ‘warm’ and ‘cold’ sister lineages. This indicates a non-random diversification on the C. rugulosa species complex associated with late Pliocene climate in the region. We interpreted the results as the diversification of the species complex were mainly driven by ecological diversification linked to past climate change, along with geographical isolation
Predicting Landscape-Genetic Consequences of Habitat Loss, Fragmentation and Mobility for Multiple Species of Woodland Birds
Inference concerning the impact of habitat fragmentation on dispersal and gene flow is a key theme in landscape genetics. Recently, the ability of established approaches to identify reliably the differential effects of landscape structure (e.g. land-cover composition, remnant vegetation configuration and extent) on the mobility of organisms has been questioned. More explicit methods of predicting and testing for such effects must move beyond post hoc explanations for single landscapes and species. Here, we document a process for making a priori predictions, using existing spatial and ecological data and expert opinion, of the effects of landscape structure on genetic structure of multiple species across replicated landscape blocks. We compare the results of two common methods for estimating the influence of landscape structure on effective distance: least-cost path analysis and isolation-by-resistance. We present a series of alternative models of genetic connectivity in the study area, represented by different landscape resistance surfaces for calculating effective distance, and identify appropriate null models. The process is applied to ten species of sympatric woodland-dependant birds. For each species, we rank a priori the expectation of fit of genetic response to the models according to the expected response of birds to loss of structural connectivity and landscape-scale tree-cover. These rankings (our hypotheses) are presented for testing with empirical genetic data in a subsequent contribution. We propose that this replicated landscape, multi-species approach offers a robust method for identifying the likely effects of landscape fragmentation on dispersal
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