204 research outputs found
Exploring Abstract, Physical, Social and Embodied Space: developing an approach for analysing museum spaces for young children
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/09/2018
- Field of study
This paper describes a collaboration between museum staff and university researchers to develop a framework for analysing museum spaces from the perspective of young children. The resultant APSE (abstract, physical, social and embodied) framework draws on spatial theories from childhood studies and architecture to consider children’s museum visiting from a spatial perspective. Starting with space not only foregrounds the role places, objects and bodies play in how experiences are constituted, but also resists linearity and predictability of mainstream educational policy discourses about young children’s learning. As place, children and objects entangle together, they design and make one another. We draw upon Massey’s description of the “chance of space”, in which people, objects and places become entangled in unpredictable and unknowable ways, to consider the potential of the APSE framework to offer alternative framings of children in museums
Young children’s museum geographies; spatial, material and bodily ways of knowing
- Publication venue
- 'Informa UK Limited'
- Publication date
- 09/07/2018
- Field of study
In this guest editorial we outline a new field of children’s museum geographies. We do this by opening up a space for the reader to engage with a collection of papers that trace embodiment, tacit and emplaced knowing, material entanglements and non-representational aspects of experience in accounts of children’s presence in museums. We hope that this special issue will act as an impetus for further working, thinking and collaborating, firstly by disrupting the conflation of children in museums with narrowing notions such as learning and talk, and secondly by highlighting the rich potential of museums as a space of interest for the field of children’s geographies
Barriers to effective discharge planning: a qualitative study investigating the perspectives of frontline healthcare professionals
- Author
- A Driscoll
- AC Strauss
- Annie WL Cheung
- C Pope
- C Williams
- Carrie HK Yam
- CHK Yam
- CJ Hyde
- CM Ashton
- CO Phillips
- DB Preen
- Department of Human Services Victoria
- DR Calkins
- EF Philbin
- EI Williams
- Eliza LY Wong
- ELY Wong
- ELY Wong
- Eng-Kiong Yeoh
- ER Marcantonio
- EZ Oddone
- FA McAlister
- Fiona YY Wong
- Frank WK Chan
- G Hedges
- H McKenna
- H Summerton
- IA Scott
- J Birmingham
- J Mamon
- JW Thomas
- K Evans
- KH Bowles
- M Funk
- M Naylor
- M Skeet
- MD Naylor
- Michael CM Leung
- MK Anthony
- National Health Services
- P Curran
- P Petersson
- R Gautam
- R Watts
- S Payne
- S Procter
- SA Hunt
- SV Katikireddi
- YM Cua
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
<p>Abstract</p> <p>Background</p> <p>Studies have shown that effective discharge planning is one of the key factors related to the quality of inpatient care and unnecessary hospital readmission. The perception and understanding of hospital discharge by health professionals is important in developing effective discharge planning. The aims of this present study were to explore the perceived quality of current hospital discharge from the perspective of health service providers and to identify barriers to effective discharge planning in Hong Kong.</p> <p>Methods</p> <p>Focus groups interviews were conducted with different healthcare professionals who were currently responsible for coordinating the discharge planning process in the public hospitals. The discussion covered three main areas: current practice on hospital discharge, barriers to effective hospital discharge, and suggested structures and process for an effective discharge planning system.</p> <p>Results</p> <p>Participants highlighted that there was no standardized hospital-wide discharge planning and policy-driven approach in public health sector in Hong Kong. Potential barriers included lack of standardized policy-driven discharge planning program, and lack of communication and coordination among different health service providers and patients in both acute and sub-acute care provisions which were identified as mainly systemic issues. Improving the quality of hospital discharge was suggested, including a multidisciplinary approach with clearly identified roles among healthcare professionals. Enhancement of health professionals' communication skills and knowledge of patient psychosocial needs were also suggested.</p> <p>Conclusions</p> <p>A systematic approach to develop the structure and key processes of the discharge planning system is critical in ensuring the quality of care and maximizing organization effectiveness. In this study, important views on barriers experienced in hospital discharge were provided. Suggestions for building a comprehensive, system-wide, and policy-driven discharge planning process with clearly identified staff roles were raised. Communication and coordination across various healthcare parties and provisions were also suggested to be a key focus.</p
Endothelial dysfunction and glycocalyx shedding in heart failure:insights from patients receiving cardiac resynchronisation therapy
- Author
- AC Pouleur
- AL Sverdlov
- AM Candia
- Andrew D. McGavigan
- AW Mulivor
- C Hall
- C Çekiç
- Chukwudiebube N. Ajaero
- CS Hayward
- DR Warriner
- E Schepers
- E Schepers
- ES Chung
- FE Curry
- FM Neves
- H Kolarova
- H Krum
- HH Lipowsky
- HH Lipowsky
- J Tromp
- JG Cleland
- John D. Horowitz
- JT Kielstein
- K Enomoto
- K Yufu
- L Kalinowski
- M Sugiura
- Margaret A. Arstall
- Michael P. Frenneaux
- MR Bristow
- MV Pitzalis
- N Procter
- Nathan E. K. Procter
- R Kelly
- RM Lang
- S Mochizuki
- SD Katz
- T Heresztyn
- Tamila Heresztyn
- TH Nguyen
- Wang X-Q Nigro P, World C, Fujiwara K, Yan C, Berk BC
- X Zhang
- Yuliy Y. Chirkov
- YY Chirkov
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/02/2020
- Field of study
To determine (a) whether chronic heart failure with reduced ejection fraction (HFrEF) is associated with increased glycocalyx shedding; (b) whether glycocalyx shedding in HFrEF with left ventricular dyssynchrony is related to inflammation, endothelial dysfunction and/or redox stress and is ameliorated by cardiac resynchronisation therapy. Glycocalyx shedding has been reported to be increased in heart failure and is a marker of increased mortality. Its role in dyssynchronous systolic heart failure and the effects of cardiac resynchronisation therapy (CRT) are largely unknown. Twenty-six patients with dyssynchronous HFrEF were evaluated before and 6 months after CRT insertion. Echocardiographic septal to posterior wall delay (SPWD) assessed intra-ventricular mechanical dyssynchrony, and quality of life, integrity of nitric oxide (NO) signalling, inflammatory and redox-related biomarkers were measured. Glycocalyx shedding was quantitated via plasma levels of the glycocalyx component, syndecan-1. Syndecan-1 levels pre-CRT were inversely correlated with LVEF (r = - 0.45, p = 0.02) and directly with SPWD (r = 0.44, p = 0.02), QOL (r = 0.39, p = 0.04), plasma NT-proBNP (r = 0.43, p = 0.02), and the inflammatory marker, symmetric dimethylarginine (SDMA) (r = 0.54, p = 0.003). On multivariate analysis, syndecan-1 levels were predicted by SPWD and SDMA (β = 0.42, p = 0.009 and β = 0.54, p = 0.001, respectively). No significant correlation was found between syndecan-1 levels and other markers of endothelial dysfunction/inflammatory activation. Following CRT there was no significant change in syndecan-1 levels. In patients with dyssynchronous HFrEF, markers of glycocalyx shedding are associated with the magnitude of mechanical dyssynchrony and elevation of SDMA levels and inversely with LVEF. However, CRT does not reverse this process
Prader-Willi syndrome: A primer for clinicians
- Author
- A Akefeldt
- A Akefeldt
- A Crino
- A Dimitropoulos
- A Goldstone
- A Prader
- A Reis
- A Schulze
- A Vogels
- A Vogels
- AA Menendez
- AB Grossman
- AC Lindgren
- AJ Holland
- AJ Holland
- AL Carrel
- AL Carrel
- AL Richdale
- AM Haqq
- AN Vgontzas
- AN Vgontzas
- AP Goldstone
- AP Maas
- B Helbing-Zwanenberg
- B Whitman
- Barbara Whitman
- C Hoybye
- C Mantoulan
- CC Glenn
- CC Glenn
- D Caffermann
- DA Festen
- DA Festen
- DA Festen
- DA Schoeller
- DJ Clarke
- E Roof
- EM Dykens
- EM Dykens
- EM Dykens
- F Benarroch
- FR Livingston
- G Grugni
- G Hertz
- G Hertz
- G Hertz
- G Hertz
- GA Bray
- Gila Hertz
- HR Mogul
- J Whittington
- JE Whittington
- JE Whittington
- JL Miller
- JR Morgan
- JS Shim
- JW Kim
- K Arron
- K Buiting
- K Koenig
- KA Chotai
- KM Milner
- L Bertella
- L Vismara
- LA Gondoni
- LA Reddy
- LM Curfs
- LM Holsen
- M Descheemaeker
- M Gunay-Aygun
- M Lindemark
- M Procter
- M Tauber
- M Torrado
- MA Angulo
- Mary Cataletto
- MG Butler
- MG Butler
- MG Butler
- MG Butler
- Moris Angulo
- NA Connell
- NA Shapira
- O Nyunt
- P Copet
- P Marzullo
- PDK Lee
- R Arens
- R Arens
- R Fronczek
- R Manni
- R Sode-Carlsen
- RD Nicholls
- RF de Lind van Wijngaarden
- S Farholt
- S McCandless
- S Nevsimalova
- SB Cassidy
- SB Cassidy
- SE Myers
- SL Einfeld
- SL Einfeld
- SL Hartley
- T Eldar-Geva
- T Greggi
- T Nagai
- T Odent
- T Odent
- U Eiholzer
- U Eiholzer
- V Cimolin
- V Gross-Tsur
- VA Holm
- VA Holm
- Z Fan
- Publication venue
- BioMed Central
- Publication date
- 01/01/2011
- Field of study
The advent of sensitive genetic testing modalities for the diagnosis of Prader-Willi syndrome has helped to define not only the phenotypic features of the syndrome associated with the various genotypes but also to anticipate clinical and psychological problems that occur at each stage during the life span. With advances in hormone replacement therapy, particularly growth hormone children born in circumstances where therapy is available are expected to have an improved quality of life as compared to those born prior to growth hormone
The Argentine Competition Law and its Enforcement
- Author
- / Ambev
- / Arcor
- / Fresenius
- / Molinos
- / Newscorp
- / Pepsi
- / Telefonica
- / Totalinef
- /Ac Inversora-Atl�ntida Telefonica
- A Lafalla Vs. Juan
- A Savant
- Aeropuertos Argentina
- Arcor/La Campagnola
- Buenos Aires
- Cndc Vs
- Cndc Vs
- D G Goyder
- Fecliba Vs. Roux
- German Coloma
- Germ�n Coloma
- Guillermo Cabanellas
- Liberty Media-Hicks/Cablevision
- Manfred
- Oca/Correo Argentino
- Oecd
- Others Fecra
- Oxford
- Paul Joskow
- Petrobras/Eg3
- Petrobras/P�rez Companc
- Procter &
- Staff M�dico Vs
- Teledigital/Esmeralda-Venado Tuerto Television
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2007
- Field of study
This article analyzes the basic characteristics of the Argentine competition law and the way in which it has been enforced in several important antitrust cases. We begin with a section that introduces the evolution of the law, followed by another section about the basic economic and legal principles underlying that law. The rest of the article describes the enforcement of the law, in a number of cases that involve collusive practices, exclusionary practices, vertical restraints, abuses of dominant position, and mergers
Measurement and interpretation of same-sign W boson pair production in association with two jets in pp collisions at s = 13 TeV with the ATLAS detector
- Author
- Aad G
- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Abusleme Hoffman AC
- Acharya BS
- Adam Bourdarios C
- Adamczyk L
- Adamek L
- Addepalli SV
- Addison MJ
- Adelman J
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agaras MN
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ahuja S
- Ai X
- Aielli G
- Aikot A
- Ait Tamlihat M
- Aitbenchikh B
- Aizenberg I
- Akbiyik M
- Akimov AV
- Akiyama D
- Akolkar NN
- Al Khoury K
- Alberghi GL
- Albert J
- Albicocco P
- Albouy GL
- Alderweireldt S
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi F
- Algren M
- Alhroob M
- Ali B
- Ali HMJ
- Ali S
- Alibocus SW
- Aliev M
- Alimonti G
- Alkakhi W
- Allaire C
- Allbrooke BMM
- Allen JF
- Allendes Flores CA
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alvarez Estevez M
- Alvarez Fernandez A
- Alves Cardoso M
- Alviggi MG
- Aly M
- Amaral Coutinho Y
- Ambler A
- Amelung C
- Amerl M
- Ames CG
- Amidei D
- Amor Dos Santos SP
- Amos KR
- Ananiev V
- Anastopoulos C
- Andeen T
- Anders JK
- Andrean SY
- Andreazza A
- Angelidakis S
- Angerami A
- Anisenkov AV
- Annovi A
- Antel C
- Anthony MT
- Antipov E
- Antonelli M
- Anulli F
- Aoki M
- Aoki T
- Aparisi Pozo JA
- Aparo MA
- Aperio Bella L
- Appelt C
- Apyan A
- Aranzabal N
- Arcangeletti C
- Arce ATH
- Arena E
- Arguin J-F
- Argyropoulos S
- Arling J-H
- Arnaez O
- Arnold H
- Artoni G
- Asada H
- Asai K
- Asai S
- Asbah NA
- Assamagan K
- Astalos R
- Atashi S
- Atkin RJ
- Atkinson M
- Atmani H
- Atmasiddha PA
- Augsten K
- Auricchio S
- Auriol AD
- Austrup VA
- Avolio G
- Axiotis K
- Azuelos G
- Babal D
- Bachacou H
- Bachas K
- Bachiu A
- Backman F
- Badea A
- Bagnaia P
- Bahmani M
- Bailey AJ
- Bailey VR
- Baines JT
- Baines L
- Bakalis C
- Baker OK
- Bakos E
- Bakshi Gupta D
- Balakrishnan V
- Balasubramanian R
- Baldin EM
- Balek P
- Ballabene E
- Balli F
- Baltes LM
- Balunas WK
- Balz J
- Banas E
- Bandieramonte M
- Bandyopadhyay A
- Bansal S
- Barak L
- Barakat M
- Barberio EL
- Barberis D
- Barbero M
- Barel MZ
- Barends KN
- Barillari T
- Barisits M-S
- Barklow T
- Baron Moreno DA
- Baron P
- Baroncelli A
- Barone G
- Barr AJ
- Barr JD
- Barranco Navarro L
- Barreiro Guimarães da Costa J
- Barreiro F
- Barron U
- Barros Teixeira MG
- Barsov S
- Bartels F
- Bartoldus R
- Barton AE
- Bartos P
- Basan A
- Baselga M
- Bassalat A
- Basso MJ
- Basson CR
- Bates RL
- Batlamous S
- Batley JR
- Batool B
- Battaglia M
- Battulga D
- Bauce M
- Bauer M
- Bauer P
- Bazzano Hurrell LT
- Beacham JB
- Beau T
- Beauchemin PH
- Becherer F
- Bechtle P
- Beck HP
- Becker K
- Becot C
- Beddall AJ
- Bednyakov VA
- Bee CP
- Beemster LJ
- Beermann TA
- Begalli M
- Begel M
- Behera A
- Behr JK
- Beirer JF
- Beisiegel F
- Belfkir M
- Bella G
- Bellagamba L
- Bellerive A
- Bellos P
- Beloborodov K
- Belyaev NL
- Benchekroun D
- Bendebba F
- Benhammou Y
- Benoit M
- Bensinger JR
- Bentvelsen S
- Beresford L
- Beretta M
- Bergeaas Kuutmann E
- Berger N
- Bergmann B
- Beringer J
- Bernardi G
- Bernius C
- Bernlochner FU
- Bernon F
- Berry T
- Berta P
- Berthold A
- Bertram IA
- Bethke S
- Betti A
- Bevan AJ
- Bhamjee M
- Bhatta S
- Bhattacharya DS
- Bhattarai P
- Bhopatkar VS
- Bi R
- Bianchi RM
- Bianco G
- Biebel O
- Bielski R
- Biglietti M
- Billoud TRV
- Bindi M
- Bingul A
- Bini C
- Biondini A
- Birch-sykes CJ
- Bird GA
- Birman M
- Biros M
- Biryukov S
- Bisanz T
- Bisceglie E
- Biswal JP
- Biswas D
- Bitadze A
- Bjørke K
- Bloch I
- Blocker C
- Blue A
- Blumenschein U
- Blumenthal J
- Bobbink GJ
- Bobrovnikov VS
- Boehler M
- Boehm B
- Bogavac D
- Bogdanchikov AG
- Bohm C
- Boisvert V
- Bokan P
- Bold T
- Bomben M
- Bona M
- Boonekamp M
- Booth CD
- Borbély AG
- Bordulev IS
- Borecka-Bielska HM
- Borgna LS
- Borissov G
- Bortoletto D
- Boscherini D
- Bosman M
- Bossio Sola JD
- Bouaouda K
- Bouchhar N
- Boudreau J
- Bouhova-Thacker EV
- Boumediene D
- Bouquet R
- Boveia A
- Boyd J
- Boye D
- Boyko IR
- Bracinik J
- Brahimi N
- Brandt G
- Brandt O
- Braren F
- Brau B
- Brau JE
- Brener R
- Brenner L
- Brenner R
- Bressler S
- Britton D
- Britzger D
- Brock I
- Brooijmans G
- Brooks WK
- Brost E
- Brown LM
- Bruce LE
- Bruckler TL
- Bruckman de Renstrom PA
- Bruni A
- Bruni G
- Bruschi M
- Bruscino N
- Brüers B
- Buanes T
- Buat Q
- Buchin D
- Buckley AG
- Bulekov O
- Bullard BA
- Burdin S
- Burgard CD
- Burger AM
- Burghgrave B
- Burlayenko O
- Burr JTP
- Burton CD
- Burzynski JC
- Busch EL
- Bussey PJ
- Butler JM
- Buttar CM
- Butterworth JM
- Buttinger W
- Buxo Vazquez CJ
- Buzykaev AR
- Büscher V
- Cabrera Urbán S
- Cadamuro L
- Caforio D
- Cai H
- Cai Y
- Cairo VMM
- Cakir O
- Calace N
- Calafiura P
- Calderini G
- Calfayan P
- Callea G
- Caloba LP
- Calvet D
- Calvet S
- Calvet TP
- Calvetti M
- Camacho Toro R
- Camarda S
- Camarero Munoz D
- Camarri P
- Camerlingo MT
- Cameron D
- Camincher C
- Campanelli M
- Camplani A
- Canale V
- Canesse A
- Cantero J
- Cao Y
- Capocasa F
- Capua M
- Carbone A
- Cardarelli R
- Cardenas JCJ
- Cardillo F
- Carli T
- Carlino G
- Carlotto JI
- Carlson BT
- Carlson EM
- Carminati L
- Carnelli A
- Carnesale M
- Caron S
- Carquin E
- Carratta G
- Carrio Argos F
- Carrá S
- Carter JWS
- Carter TM
- Casado MP
- Caspar M
- Castiglia EG
- Castillo Garcia L
- Castillo Gimenez V
- Castillo FL
- Castro NF
- Catinaccio A
- Catmore JR
- Cavaliere V
- Cavalli N
- Cavasinni V
- Cekmecelioglu YC
- Celebi E
- Celli F
- Centonze MS
- Cepaitis V
- Cerny K
- Cerqueira AS
- Cerri A
- Cerrito L
- Cerutti F
- Cervato B
- Cervelli A
- Cesarini G
- Cetin SA
- Chadi Z
- Chakraborty D
- Chan J
- Chan WY
- Chapman JD
- Chapon E
- Chargeishvili B
- Charlton DG
- Charman TP
- Chatterjee M
- Chauhan C
- Chekanov S
- Chekulaev SV
- Chelkov GA
- Chen A
- Chen B
- Chen B
- Chen H
- Chen H
- Chen J
- Chen J
- Chen M
- Chen S
- Chen SJ
- Chen X
- Chen X
- Chen Y
- Cheng CL
- Cheng HC
- Cheong S
- Cheplakov A
- Cheremushkina E
- Cherepanova E
- Cherkaoui El Moursli R
- Cheu E
- Cheung K
- Chevalier L
- Chiarella V
- Chiarelli G
- Chiedde N
- Chiodini G
- Chisholm AS
- Chitan A
- Chitishvili M
- Chizhov MV
- Choi K
- Chomont AR
- Chou Y
- Chow EYS
- Chowdhury T
- Chu KL
- Chu MC
- Chu X
- Chudoba J
- Chwastowski JJ
- Cieri D
- Ciesla KM
- Cindro V
- Ciocio A
- Cirotto F
- Citron ZH
- Citterio M
- Ciubotaru DA
- Ciungu BM
- Clark A
- Clark PJ
- Clavijo Columbie JM
- Clawson SE
- Clement C
- Clercx J
- Coadou Y
- Cobal M
- Coccaro A
- Coelho Barrue RF
- Coelho Lopes De Sa R
- Coelli S
- Cohen H
- Coimbra AEC
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- Collot J
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- Connell MP
- Connell SH
- Connelly IA
- Conroy EI
- Conventi F
- Cooke HG
- Cooper-Sarkar AM
- Cordeiro Oudot Choi A
- Cormier F
- Corpe LD
- Corradi M
- Corriveau F
- Cortes-Gonzalez A
- Costa MJ
- Costanza F
- Costanzo D
- Cote BM
- Cowan G
- Cranmer K
- Cremonini D
- Crescioli F
- Cristinziani M
- Cristoforetti M
- Croft V
- Crosby JE
- Crosetti G
- Crépé-Renaudin S
- Cueto A
- Cuhadar Donszelmann T
- Cui H
- Cui Z
- Cunningham WR
- Curcio F
- Czodrowski P
- Czurylo MM
- Da Cunha Sargedas De Sousa MJ
- Da Fonseca Pinto JV
- Da Via C
- Dabrowski W
- Dado T
- Dahbi S
- Dai T
- Dal Santo D
- Dallapiccola C
- Dam M
- Damp J
- Dandoy JR
- Daneri MF
- Danninger M
- Dao V
- Darbo G
- Darmora S
- Das SJ
- David C
- Davidek T
- Davis-Purcell B
- Dawson I
- Day-hall HA
- De Asmundis R
- De Biase N
- De Castro S
- De Groot N
- de Jong P
- De la Torre H
- De Maria A
- De Salvo A
- De Sanctis U
- De Santo A
- De Vivie De Regie JB
- De K
- Dedovich DV
- Degens J
- Deiana AM
- Del Corso F
- Del Peso J
- Del Rio F
- Deliot F
- Delitzsch CM
- Della Pietra M
- Della Volpe D
- Dell’Acqua A
- Dell’Asta L
- Delmastro M
- Delsart PA
- Demers S
- Demichev M
- Denisov SP
- Derendarz D
- Derue F
- Dervan P
- Desch K
- Deutsch C
- Di Bello FA
- Di Ciaccio A
- Di Ciaccio L
- Di Domenico A
- Di Donato C
- Di Girolamo A
- Di Gregorio G
- Di Luca A
- Di Micco B
- Di Nardo R
- Diaconu C
- Diamantopoulou M
- Dias Do Vale T
- Dias FA
- Diaz Capriles FG
- Diaz MA
- Didenko M
- Diehl EB
- Diehl L
- Diez Pardos C
- Dimitriadi C
- Dimitrievska A
- Dingfelder J
- Dinu I-M
- Dittmeier SJ
- Dittus F
- Djama F
- Djobava T
- Djuvsland JI
- Doglioni C
- Dohnalova A
- Dolejsi J
- Dolezal Z
- Dona KM
- Donadelli M
- Dong B
- Donini J
- Dopke J
- Doria A
- Dos Santos Fernandes N
- Dougan P
- Dova MT
- Doyle AT
- Draguet MA
- Dreyer E
- Drivas-koulouris I
- Drobac AS
- Drozdova M
- du Pree TA
- Du D
- Dubinin F
- Dubovsky M
- Duchovni E
- Duckeck G
- Ducu OA
- Duda D
- Dudarev A
- Duden ER
- Duflot L
- Dumitriu AE
- Dunford M
- Dungs S
- Dunne K
- Duperrin A
- Duran Yildiz H
- Durglishvili A
- Dwyer BL
- Dyckes GI
- Dyndal M
- Dysch S
- Dziedzic BS
- Díez Cornell S
- Dührssen M
- Dülsen C
- Düren M
- D’amen G
- D’Amico V
- D’Auria S
- D’Eramo L
- D’Onofrio A
- D’Onofrio M
- D’uffizi M
- Earnshaw ZO
- Eberwein GH
- Eckerova B
- Eggebrecht S
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- Ehrke LF
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- Zhemchugov A
- Zheng J
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- Zhong D
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- Zhulanov V
- Zimine NI
- Zinsser J
- Ziolkowski M
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- Zou W
- Zwalinski L
- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 01/04/2024
- Field of study
This paper presents the measurement of fducial and diferential cross sections for both the inclusive and electroweak production of a same-sign W-boson pair in association with two jets (W±W±jj) using 139 fb−1 of proton-proton collision data recorded at a centre-of-mass energy of √s = 13 TeV by the ATLAS detector at the Large Hadron Collider. The analysis is performed by selecting two same-charge leptons, electron or muon, and at least two jets with large invariant mass and a large rapidity diference. The measured fducial cross sections for electroweak and inclusive W±W±jj production are 2.92 ± 0.22 (stat.) ± 0.19 (syst.)fb and 3.38±0.22 (stat.)±0.19 (syst.)fb, respectively, in agreement with Standard Model predictions. The measurements are used to constrain anomalous quartic gauge couplings by extracting 95% confdence level intervals on dimension-8 operators. A search for doubly charged Higgs bosons H±± that are produced in vector-boson fusion processes and decay into a same-sign W boson pair is performed. The largest deviation from the Standard Model occurs for an H±± mass near 450 GeV, with a global signifcance of 2.5 standard deviations
Combination of searches for heavy spin-1 resonances using 139 fb−1 of proton-proton collision data at s = 13 TeV with the ATLAS detector
- Author
- Aad G
- Aakvaag E
- Abbott B
- Abeling K
- Abicht NJ
- Abidi SH
- Aboelela M
- Aboulhorma A
- Abramowicz H
- Abreu H
- Abulaiti Y
- Acharya BS
- Ackermann A
- Adam Bourdarios C
- Adamczyk L
- Addepalli SV
- Addison MJ
- Adelman J
- Adiguzel A
- Adye T
- Affolder AA
- Afik Y
- Agaras MN
- Agarwala J
- Aggarwal A
- Agheorghiesei C
- Ahmad A
- Ahmadov F
- Ahmed WS
- Ahuja S
- Ai X
- Aielli G
- Aikot A
- Ait Tamlihat M
- Aitbenchikh B
- Aizenberg I
- Akbiyik M
- Akimov AV
- Akiyama D
- Akolkar NN
- Aktas S
- Al Khoury K
- Alberghi GL
- Albert J
- Albicocco P
- Albouy GL
- Alderweireldt S
- Alegria ZL
- Aleksa M
- Aleksandrov IN
- Alexa C
- Alexopoulos T
- Alfonsi F
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- Alhroob M
- Ali B
- Ali HMJ
- Ali S
- Alibocus SW
- Aliev M
- Alimonti G
- Alkakhi W
- Allaire C
- Allbrooke BMM
- Allen JF
- Allendes Flores CA
- Allport PP
- Aloisio A
- Alonso F
- Alpigiani C
- Alvarez Estevez M
- Alvarez Fernandez A
- Alves Cardoso M
- Alviggi MG
- Aly M
- Amaral Coutinho Y
- Ambler A
- Amelung C
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- Amirie KJ
- Amor Dos Santos SP
- Amos KR
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- Zhemchugov A
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- Åkesson TPA
- Öncel ÖO
- Ženiš T
- Živković L
- Publication venue
- Springer Nature
- Publication date
- 19/04/2024
- Field of study
A combination of searches for new heavy spin-1 resonances decaying into different pairings of W, Z, or Higgs bosons, as well as directly into leptons or quarks, is presented. The data sample used corresponds to 139 fb−1 of proton-proton collisions at
= 13 TeV collected during 2015–2018 with the ATLAS detector at the CERN Large Hadron Collider. Analyses selecting quark pairs (qq, bb,
, and tb) or third-generation leptons (τν and ττ) are included in this kind of combination for the first time. A simplified model predicting a spin-1 heavy vector-boson triplet is used. Cross-section limits are set at the 95% confidence level and are compared with predictions for the benchmark model. These limits are also expressed in terms of constraints on couplings of the heavy vector-boson triplet to quarks, leptons, and the Higgs boson. The complementarity of the various analyses increases the sensitivity to new physics, and the resulting constraints are stronger than those from any individual analysis considered. The data exclude a heavy vector-boson triplet with mass below 5.8 TeV in a weakly coupled scenario, below 4.4 TeV in a strongly coupled scenario, and up to 1.5 TeV in the case of production via vector-boson fusion
Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease
- Author
- A Abbate
- A Abhyankar
- A Adams
- A Agafina
- A Akyea-Djamson
- A Alan
- A Alfieri
- A Alfrey
- A Alvarisqueta
- A Amos
- A Anadiotis
- A Anneveldt
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- Zalazar L
- Zaman A
- Zangroniz P
- Zarate J
- Zareczky P
- Zarifis I
- Zdrenghea D
- Zebrack J
- Zena N
- Zhang J
- Zhang W
- Zhang Y
- Zhao R
- Zhou H
- Zidova M
- Zielinski M
- Zieve F
- Zineldine A.
- Zirlik A
- Zucchetti C
- Publication venue
- 'Massachusetts Medical Society'
- Publication date
- 01/01/2017
- Field of study
Background: Experimental and clinical data suggest that reducing inflammation without affecting lipid levels may reduce the risk of cardiovascular disease. Yet, the inflammatory hypothesis of atherothrombosis has remained unproved. Methods: We conducted a randomized, double-blind trial of canakinumab, a therapeutic monoclonal antibody targeting interleukin-1β, involving 10,061 patients with previous myocardial infarction and a high-sensitivity C-reactive protein level of 2 mg or more per liter. The trial compared three doses of canakinumab (50 mg, 150 mg, and 300 mg, administered subcutaneously every 3 months) with placebo. The primary efficacy end point was nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death. RESULTS: At 48 months, the median reduction from baseline in the high-sensitivity C-reactive protein level was 26 percentage points greater in the group that received the 50-mg dose of canakinumab, 37 percentage points greater in the 150-mg group, and 41 percentage points greater in the 300-mg group than in the placebo group. Canakinumab did not reduce lipid levels from baseline. At a median follow-up of 3.7 years, the incidence rate for the primary end point was 4.50 events per 100 person-years in the placebo group, 4.11 events per 100 person-years in the 50-mg group, 3.86 events per 100 person-years in the 150-mg group, and 3.90 events per 100 person-years in the 300-mg group. The hazard ratios as compared with placebo were as follows: in the 50-mg group, 0.93 (95% confidence interval [CI], 0.80 to 1.07; P = 0.30); in the 150-mg group, 0.85 (95% CI, 0.74 to 0.98; P = 0.021); and in the 300-mg group, 0.86 (95% CI, 0.75 to 0.99; P = 0.031). The 150-mg dose, but not the other doses, met the prespecified multiplicity-adjusted threshold for statistical significance for the primary end point and the secondary end point that additionally included hospitalization for unstable angina that led to urgent revascularization (hazard ratio vs. placebo, 0.83; 95% CI, 0.73 to 0.95; P = 0.005). Canakinumab was associated with a higher incidence of fatal infection than was placebo. There was no significant difference in all-cause mortality (hazard ratio for all canakinumab doses vs. placebo, 0.94; 95% CI, 0.83 to 1.06; P = 0.31). Conclusions: Antiinflammatory therapy targeting the interleukin-1β innate immunity pathway with canakinumab at a dose of 150 mg every 3 months led to a significantly lower rate of recurrent cardiovascular events than placebo, independent of lipid-level lowering. (Funded by Novartis; CANTOS ClinicalTrials.gov number, NCT01327846.
The neighbourhood physical environment and active travel in older adults: a systematic review and meta-analysis
- Author
- A Barnett
- A Barnett
- A Etman
- A Martin
- A Nathan
- A Nathan
- A Nathan
- AA Laverty
- AC King
- AC King
- AM Chudyk
- Andrea Nathan
- Anthony Barnett
- B Chaix
- B Giles-Corti
- BE Saelens
- BJ Boruff
- BJ Kelly
- CF Mendes de Leon
- D Ding
- D King
- D Moher
- D Ogilvie
- D Rainham
- DA Dillman
- David W. Barnett
- DD Dunlop
- Department of Infrastructure and transport
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Cerin
- E Leslie
- E Procter-Gray
- Ester Cerin
- GR McCormack
- HB Menz
- J Boone-Heinonen
- J Cauwenberg Van
- J Cauwenberg Van
- J Cauwenberg Van
- J Cauwenberg Van
- J Cohen
- J Davey
- J Garrard
- J Jarrett
- J Kerr
- J Kerr
- J Pelclová
- J Sallis
- J Woodcock
- JA Carlson
- Jelle van Cauwenberg
- JF Sallis
- JL Maisel
- JPT Higgins
- JR Willis
- K Berkemeyer
- K Gebel
- K Witten
- KE Lamb
- KK Davison
- KL Cain
- L Foley
- L Frank
- LB Christiansen
- LL Barnes
- LT Tsai
- M Bland
- M Johnson
- M Moniruzzaman
- M Moniruzzaman
- M Moran
- M Tainio
- M Takemoto
- MA Alfonzo
- MG Davis
- MR Franco
- MS Nyunt
- MW Corseuil
- MW Corseuil Giehl
- NL Bracy
- NW Burton
- P Kelly
- PA Jackson
- PK Patterson
- R Barnes
- R Ewing
- R Rosenthal
- R Shigematsu
- S Foster
- S Inoue
- S O’Hern
- SC Webber
- SK Keadle
- SL Handy
- T Sugiyama
- TL Kolbe-Alexander
- V Holle Van
- V Holle Van
- V Holle Van
- World Health Organisation
- World Health Organization
- X Cao
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
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