Predictors of mental health in emerging adult offspring of lesbian-parent families

Emerging adulthood is a new, distinct life stage for 18- to 29-year-olds in the United States. In the sixth wave of data collection in a longitudinal cohort study (started in 1986), predictors of mental health were examined in the emerging adult offspring within lesbian-parent parent families. The donor-conceived offspring were 25 years old. In cross-sectional analyses, we assessed whether their mental health (life satisfaction and behavioral/emotional problems) was associated with personal characteristics, family characteristics, quality of important relationships, and experiences of homophobic stigmatization. The findings revealed that the predictors of mental health in these offspring were typical of what has been previously reported on emerging adults. However, offspring who reported stigmatization because of their parents’ sexual identity had higher rates of behavioral/emotional problems than those who did not

Thermal reaction norms and the scale of temperature variation: latitudinal vulnerability of intertidal Nacellid limpets to climate change

The thermal reaction norms of 4 closely related intertidal Nacellid limpets, Antarctic (Nacella concinna), New Zealand (Cellana ornata), Australia (C. tramoserica) and Singapore (C. radiata), were compared across environments with different temperature magnitude, variability and predictability, to test their relative vulnerability to different scales of climate warming. Lethal limits were measured alongside a newly developed metric of “duration tenacity”, which was tested at different temperatures to calculate the thermal reaction norm of limpet adductor muscle fatigue. Except in C. tramoserica which had a wide optimum range with two break points, duration tenacity did not follow a typical aerobic capacity curve but was best described by a single break point at an optimum temperature. Thermal reaction norms were shifted to warmer temperatures in warmer environments; the optimum temperature for tenacity (Topt) increased from 1.0°C (N. concinna) to 14.3°C (C. ornata) to 18.0°C (an average for the optimum range of C. tramoserica) to 27.6°C (C. radiata). The temperature limits for duration tenacity of the 4 species were most consistently correlated with both maximum sea surface temperature and summer maximum in situ habitat logger temperature. Tropical C. radiata, which lives in the least variable and most predictable environment, generally had the lowest warming tolerance and thermal safety margin (WT and TSM; respectively the thermal buffer of CTmax and Topt over habitat temperature). However, the two temperate species, C. ornata and C. tramoserica, which live in a variable and seasonally unpredictable microhabitat, had the lowest TSM relative to in situ logger temperature. N. concinna which lives in the most variable, but seasonally predictable microhabitat, generally had the highest TSMs. Intertidal animals live at the highly variable interface between terrestrial and marine biomes and even small changes in the magnitude and predictability of their environment could markedly influence their future distributions

Cancer du sein au Cameroun, profil histo-épidémiologique: à propos de 3044 cas

Décrire les caractéristiques épidémiologiques et histo-pathologiques des tumeurs malignes du sein au Cameroun. Il s'agissait d'une étude rétrospective descriptive portant sur les tumeurs malignes du sein, colligées, dans les registres des différents laboratoires d'Anatomie Pathologique publiques et privés repartis dans cinq régions (centre, littoral, Ouest, Nord-ouest, Sud-ouest), pendant une période de 10 ans  2004-2013). Les paramètres étudiés étaient la fréquence, l'âge, le sexe, la localisation, le type et le grade histologique, et les récepteurs hormonaux. Un total de 3044 cas de cancers du sein a été recensé, soit une fréquence annuelle de 304,4 cas en moyenne. Le sexe féminin était le plus représenté avec 2971 cas (97,60%) et les hommes avec 73 cas (2,40%), soit un sexe ratio (H/F) de 0,02. L'âge moyen des patients était de 46±15,87 ans, avec des extrêmes de 13 et 95 ans. Selon la localisation, le sein gauche était atteint dans 1244 cas (52%) et le sein droit dans 1115 cas (47%). Au plan histologique, on retrouvait essentiellement des carcinomes avec 96,50% des cas, des sarcomes 1,39%, des lymphomes 1,07% et la maladie de Paget du mamelon, 1,03%. Les tumeurs épithéliales étaient infiltrantes dans 2049 cas (84,46%), avec une prédominance du carcinome canalaire infiltrant (1870 cas) et non infiltrantes dans 377 cas (15,54%). Le grade histo-pronostic de SBR avait révélé une prédominance du grade II dans 66% des cas. Les cancers du sein restent une pathologie fréquente au Cameroun et atteignent principalement la population féminine en âge de procréer. Ils sont caractérisés par la prédominance du carcinome canalaire infiltrant

Low-temperature co-sintering for fabrication of zirconia/ceria bi-layer electrolyte via tape casting using a Fe2O3 sintering aid

Bilayer electrolytes have potential in solid oxide cells to improve ionic conduction whilst blocking electronic conduction. GDC/YSZ bilayer electrolyte processinghas provenproblematic due to thermochemical instability at high sintering temperatures. We first match the shrinkage profile of the two bulk materials using a Fe2O3 sintering additive. Additions of 5 mol% of Fe2O3 in the GDC layer and 2 mol% of Fe2O3 in the YSZ layer prevents delamination during co-sintering. The addition of Fe2O3 promotes densification, enabling achievement of a dense bilayer at a reduced sintering temperature of 1300 ◦C; ∼150 ◦C below conventional sintering temperatures. Elemental analysis showed the compositional distribution curves across the bilayer interface to be asymmetric when Fe2O3 is employed. The Fe2O3 increases the total conductivity of the bilayer electrolyte by an order of magnitude; this is explained by the effect of Fe2O3 on reducing the resistive solid solution interlayer at YSZ/GDC interface from ∼15 to ∼5 m