Reduced contextually induced muscle thermogenesis in rats with calorie restriction and lower aerobic fitness but not monogenic obesity

We have previously identified predator odor as a potent stimulus activating thermogenesis in skeletal muscle in rats. As this may prove relevant for energy balance and weight loss, the current study investigated whether skeletal muscle thermogenesis was altered with negative energy balance, obesity propensity seen in association with low intrinsic aerobic fitness, and monogenic obesity. First, weight loss subsequent to three weeks of 50% calorie restriction suppressed the muscle thermogenic response to predator odor. Next, we compared rats bred based on artificial selection for intrinsic aerobic fitness—high- and low-capacity runners (HCR, LCR)—that display robust leanness and obesity propensity, respectively. Aerobically fit HCR showed enhanced predator odor-induced muscle thermogenesis relative to the less-fit LCR. This contrasted with the profound monogenic obesity displayed by rats homozygous for a loss of function mutation in Melanocortin 4 receptor (Mc4rK314X/K314X rats), which showed no discernable deficit in thermogenesis. Taken together, these data imply that body size or obesity per se are not associated with deficient muscle thermogenesis. Rather, the physiological phenotype associated with polygenic obesity propensity may encompass pleiotropic mechanisms in the thermogenic pathway. Adaptive thermogenesis associated with weight loss also likely alters muscle thermogenic mechanisms.</p

Wilson line correlator in the MV model: relating the glasma to deep inelastic scattering

In the color glass condensate framework the saturation scale measured in deep inelastic scattering of high energy hadrons and nuclei can be determined from the correlator of Wilson lines in the hadron wavefunction. These same Wilson lines give the initial condition of the classical field computation of the initial gluon multiplicity and energy density in a heavy ion collision. In this paper the Wilson line correlator in both adjoint and fundamental representations is computed using exactly the same numerical procedure that has been used to calculate gluon production in a heavy ion collision. In particular the discretization of the longitudinal coordinate has a large numerical effect on the relation between the color charge density parameter g^2 mu and the saturation scale Qs. Our result for this relation is Qs = 0.6 g^2 mu, which results in the classical Yang-Mills value for the "gluon liberation coefficient" c = 1.1.Comment: 8 pages, 10 figures, RevTEX4, V2: typo corrections, V3: small clarifications, to be published in EPJ

Performance of a fine-sampling electromagnetic calorimeter prototype in the energy range from 1 to 19 GeV

The fine-sampling electromagnetic calorimeter prototype has been experimentally tested using the 1-19 GeV/c tagged beams of negatively charged particles at the U70 accelerator at IHEP, Protvino. The energy resolution measured by electrons is Delta{E}/E=2.8%/\sqrt{E} + 1.3%. The position resolution for electrons is Delta{x}=3.1 + 15.4/sqrt{E} mm in the center of the cell. The lateral non-uniformity of the prototype energy response to electrons and MIPs has turned out to be negligible. Obtained experimental results are in a good agreement with Monte-Carlo simulations.Comment: Article is prepared for pdflatex using the class elsart. 13 pages, 9 figures in 11 PDF file

Non-linear QCD dynamics and exclusive production in epep collisions

The exclusive processes in electron-proton ($ep$) interactions are an important tool to investigate the QCD dynamics at high energies as they are in general driven by the gluon content of proton which is strongly subject to parton saturation effects. In this paper we compute the cross sections for the exclusive vector meson production as well as the deeply virtual Compton scattering (DVCS) relying on the color dipole approach and considering the numerical solution of the Balitsky-Kovchegov equation including running coupling corrections. We show that the small-$x$ evolution given by this evolution equation is able to describe the DESY-HERA data and is relevant for the physics of the exclusive observables in future electron-proton colliders and in photoproduction processes to be measured in coherent interactions at the LHC.Comment: 6 pages, 4 figure

Scaling anomaly in cosmic string background

We show that the classical scale symmetry of a particle moving in cosmic string background is broken upon inequivalent quantization of the classical system, leading to anomaly. The consequence of this anomaly is the formation of single bound state in the coupling interval \gamma\in(-1,1). The inequivalent quantization is characterized by a 1-parameter family of self-adjoint extension parameter \omega. It has been conjectured that the formation of loosely bound state in cosmic string background may lead to the so called anomalous scattering cross section for the particles, which is usually seen in molecular physics.Comment: 4 pages,1 figur

Non-linear QCD dynamics in two-photon interactions at high energies

Perturbative QCD predicts that the growth of the gluon density at high energies should saturate, forming a Color Glass Condensate (CGC), which is described in mean field approximation by the Balitsky-Kovchegov (BK) equation. In this paper we study the $\gamma \gamma$ interactions at high energies and estimate the main observables which will be probed at future linear colliders using the color dipole picture. We discuss in detail the dipole - dipole cross section and propose a new relation between this quantity and the dipole scattering amplitude. The total $\gamma \gamma$, $\gamma^{*} \gamma^{*}$ cross-sections and the real photon structure function $F_2^{\gamma}(x,Q^2)$ are calculated using the recent solution of the BK equation with running coupling constant and the predictions are compared with those obtained using phenomenological models for the dipole-dipole cross section and scattering amplitude. We demonstrate that these models are able to describe the LEP data at high energies, but predict a very different behavior for the observables at higher energies. Therefore we conclude that the study of $\gamma \gamma$ interactions can be useful to constrain the QCD dynamics.Comment: 11 pages, 5 figures. Version to be published in European Physical Journal

Parity-violating Electron Deuteron Scattering and the Proton's Neutral Weak Axial Vector Form Factor

We report on a new measurement of the parity-violating asymmetry in quasielastic electron scattering from the deuteron at backward angles at Q2= 0.038 (GeV/c)2. This quantity provides a determination of the neutral weak axial vector form factor of the nucleon, which can potentially receive large electroweak corrections. The measured asymmetry A=-3.51 +/- 0.57(stat) +/- 0.58(sys)ppm is consistent with theoretical predictions. We also report on updated results of the previous experiment at Q2=0.091 (GeV/c)2, which are also consistent with theoretical predictions.Comment: 4 pages, 2 figures, submitted to Phys. Rev. Let

Next-to-leading and resummed BFKL evolution with saturation boundary

We investigate the effects of the saturation boundary on small-x evolution at the next-to-leading order accuracy and beyond. We demonstrate that the instabilities of the next-to-leading order BFKL evolution are not cured by the presence of the nonlinear saturation effects, and a resummation of the higher order corrections is therefore needed for the nonlinear evolution. The renormalization group improved resummed equation in the presence of the saturation boundary is investigated, and the corresponding saturation scale is extracted. A significant reduction of the saturation scale is found, and we observe that the onset of the saturation corrections is delayed to higher rapidities. This seems to be related to the characteristic feature of the resummed splitting function which at moderately small values of x possesses a minimum.Comment: 34 page

Measurement of the Transverse-Longitudinal Cross Sections in the p (e,e'p)pi0 Reaction in the Delta Region

Accurate measurements of the p(e,e?p)pi0 reaction were performed at Q^2=0.127(GeV/c)^2 in the Delta resonance energy region. The experiments at the MIT-Bates Linear Accelerator used an 820 MeV polarized electron beam with the out of plane magnetic spectrometer system (OOPS). In this paper we report the first simultaneous determination of both the TL and TL? (``fifth" or polarized) cross sections at low Q^{2} where the pion cloud contribution dominates the quadrupole amplitudes (E2 and C2). The real and imaginary parts of the transverse-longitudinal cross section provide both a sensitive determination of the Coulomb quadrupole amplitude and a test of reaction calculations. Comparisons with model calculations are presented. The empirical MAID calculation gives the best overall agreement with this accurate data. The parameters of this model for the values of the resonant multipoles are |M_{1+}(I=3/2)|= (40.9 \pm 0.3)10^{-3}/m_pi, CMR= C2/M1= -6.5 \pm 0.3%, EMR=E2/M1=-2.2 \pm 0.9%, where the errors are due to the experimental uncertainties.Comment: 10 pages, 3 figures, minor corrections and addition