Which factors differentiate athletes with hip/groin pain from those without? A systematic review with meta-analysis

Background: Hip and groin injuries are common in many sports. Understanding the factors differentiating athletes with hip/groin pain from those without these injuries could facilitate management and prevention. Objective: Conduct a systematic review and meta-analysis of the literature on factors differentiating athletes with and without hip/groin pain. Methods: The review was registered as PROSPERO CRD42014007416 and a comprehensive, systematic search was conducted in June 2014. Inclusion criteria were: cross-sectional, cohort or case-control study designs of n>10 that examined outcome measures differentiating athletes with and without hip/groin pain. Two authors independently screened search results, assessed study quality, and performed data extraction. Methodological heterogeneity was determined and data pooled for meta-analysis when appropriate. A best evidence synthesis was performed on the remaining outcome measures. Results: Of 2251 titles identified, 17 articles were included of which 10 were high quality. Sixty two different outcome measures were examined, 8 underwent meta-analysis. Pooled data showed strong evidence that athletes with hip/groin pain demonstrated: pain and lower strength on the adductor squeeze test, reduced range of motion in hip internal rotation and bent knee fall out; however, hip external rotation range was equivalent to controls. Strong evidence was found that lower patient-reported outcome (PRO) scores, altered trunk muscle function, and moderate evidence of bone oedema and secondary cleft sign were associated with hip/groin pain. Conclusions: PROs, pain and reduced strength on the adductor squeeze test, reduced range of motion in internal rotation and bent knee fall out are the outcome measures that best differentiate athletes with hip/groin pain from those without this pain

The role of location in residential location choice models: a review of literature

JTLU vol. 7, no. 2, pp. 3-21 (2014)Geospatial data available to researchers has increased tremendously over the last several decades, opening up opportunities to define residential location in multiple ways. This has led to a myriad of variables to define "location'' in residential location choice models. In this paper, we propose a common classification for location variables and categorize findings from a wide range of studies. We find similar preferences but different measurement methods and market segments for locations across different study regions. Recent studies consider the residential unit as choice alternative, making it possible to include a detailed description of the built environment. However, these studies are still limited in number and the inclusion of socioeconomic environment is more common. Transport land-use models can benefit from the inclusion of points of interest, such as schools, network distances, and the distance to previous locations. For the results of location choice models to be transferable to different disciplines, and avoid multi-collinearity, it is necessary to present different model specifications, including variables of interest in different disciplines

Solar uv damage and skin protection:the boosting of natural defences and healing by cosmeceuticals

As many spatial choices, residential location choices are made from a large pool of potential alternatives. This study evaluates choice sets based on households’ search preferences as a new alternative to the more commonly applied random or weighted sampling, using a recent movers survey conducted in Singapore. Residential units are taken as the unit of analysis. Descriptive analysis reveals that households search in a limited area and in a limited number of markets. Subsequently, a choice set generation algorithm is proposed that evaluates the number of alternatives available to a household based on self-reported search preferences. To a large extent the size of the universal choice set is influenced by the temporal and spatial dimension of the search process. Model results are presented that with alternatives sampled from the universal choice set. Additionally, models are presented with choice sets that take into account households’ self- reported search preferences that include dwelling size, dwelling price and possible areas. Models including spatial variables describing the social environment, combined with choice sets only including alternatives within the preferred price range, perform best. The social environment consisted of variable describing a household’s average distance to work, the distance to their parents and the average distance to the locations where they most frequently meet their five closest contacts. Other significant spatial variables included the distance to a top primary school, as well as the proximity to a mass rapid transit. Given the significance of these variables tt is proposed to further evaluate anchor and distance-based sampling

Measurement of the B0-anti-B0-Oscillation Frequency with Inclusive Dilepton Events

The $B^0$-$\bar B^0$ oscillation frequency has been measured with a sample of 23 million \B\bar B pairs collected with the BABAR detector at the PEP-II asymmetric B Factory at SLAC. In this sample, we select events in which both B mesons decay semileptonically and use the charge of the leptons to identify the flavor of each B meson. A simultaneous fit to the decay time difference distributions for opposite- and same-sign dilepton events gives $\Delta m_d = 0.493 \pm 0.012{(stat)}\pm 0.009{(syst)}$ ps$^{-1}$.Comment: 7 pages, 1 figure, submitted to Physical Review Letter

First direct observation of enhanced octupole collectivity in 146Ba

The octupole strength present in the neutron-rich, radiocative nucleus 146Ba has been experimentally determined for the first time using Coulomb excitation. To achieve this, A=146 fission fragments from CARIBU were post-accelerated by the Argonne Tandem Linac Accelerator System (ATLAS) and impinged on a thin 208Pb target. Using the GRETINA γ-ray spectrometer and the CHICO2 heavy-ion counter, the reduced transition probability B(E3; 3-→0+) was determined as 48(+21-29) W.u. The new result provides further experimental evidence for the presence of a region of octupole deformation surrounding the neutron-rich barium isotopes

Biologics Delay Progression of Crohn's Disease, but Not Early Surgery, in Children

Background & Aims: Up to 30% of patients with Crohn's disease (CD) require surgery within the first 5 years from diagnosis. We investigated the recent risk of bowel surgery in an inception cohort of pediatric patients with CD and whether early use of biologics (tumor necrosis factor antagonists) alters later disease course. Methods: We collected data from the Pediatric Inflammatory Bowel Disease Collaborative Research Group registry on 1442 children (age, ó16 y) diagnosed with CD from January 2002 through December 2014. Data were collected at diagnosis, 30 days following diagnosis, and then quarterly and during hospitalizations for up to 12 years. Our primary aim was to determine the 10-year risk for surgery in children with CD. Our secondary aim was to determine whether early use of biologics (<3 mo of diagnosis) affected risk of disease progression. Results: The 10-year risk of first bowel surgery was 26%. The 5-year risk of bowel surgery did not change from 2002 through 2014, and remained between 13% and 14%. Most surgeries occurred within 3 years from diagnosis. The only predictor of surgery was disease behavior at diagnosis. CD with inflammatory behavior had the lowest risk of surgery compared to stricturing disease, penetrating disease, or both. We associated slowing of disease progression to stricturing or penetrating disease (but not surgery) with early use of biologics, but this effect only became evident after 5 years of disease. Our results indicate that biologics slow disease progression over time (hazard ratio, 0.85; 95% CI, 0.76?0.95). Conclusions: In an analysis of data from a registry of pediatric patients with CD, we found that among those with significant and progressing disease at or shortly after presentation, early surgery is difficult to prevent, even with early use of biologics. Early use of biologics (<3 mo of diagnosis) can delay later disease progression to stricturing and/or penetrating disease, but this affect could become evident only years after initial management decisions are made

Shape coexistence and the role of axial asymmetry in 72Ge

The quadrupole collectivity of low-lying states and the anomalous behavior of the 02+ and 23+ levels in 72Ge are investigated via projectile multi-step Coulomb excitation with GRETINA and CHICO-2. A total of forty six E2 and M1 matrix elements connecting fourteen low-lying levels were determined using the least-squares search code, gosia. Evidence for triaxiality and shape coexistence, based on the model-independent shape invariants deduced from the Kumar-Cline sum rule, is presented. These are interpreted using a simple two-state mixing model as well as multi-state mixing calculations carried out within the framework of the triaxial rotor model. The results represent a significant milestone towards the understanding of the unusual structure of this nucleus

Shapes, softness, and nonyrast collectivity in 186W

Nonyrast, excited states in neutron-rich 186W were populated via inelastic-scattering reactions using beams of 136Xe nuclei accelerated to 725 and 800 MeV. Levels populated in the reactions were investigated via particleγ coincidence techniques using the Gammasphere array of high-purity germanium detectors and the compact heavy-ion counter, CHICO2. The Kπ = 2+ (γ), Kπ = 0+ and Kπ = 2− (octupole) rotational side bands were extended to spins 14¯h,12¯ h, and 13¯h, respectively. A staggering pattern observed in the energies of levels in the Kπ = 2+ band was found to be consistent with a potential that gets softer to vibration in the γ degree of freedom with increasing spin. The odd-even staggering of states in the Kπ = 2− band was found to exhibit a phase opposite to that seen in the γ band; an effect most probably associated with Coriolis coupling to other, unobserved octupole vibrational bands in 186W

The Physical Processes of CME/ICME Evolution

As observed in Thomson-scattered white light, coronal mass ejections (CMEs) are manifest as large-scale expulsions of plasma magnetically driven from the corona in the most energetic eruptions from the Sun. It remains a tantalizing mystery as to how these erupting magnetic fields evolve to form the complex structures we observe in the solar wind at Earth. Here, we strive to provide a fresh perspective on the post-eruption and interplanetary evolution of CMEs, focusing on the physical processes that define the many complex interactions of the ejected plasma with its surroundings as it departs the corona and propagates through the heliosphere. We summarize the ways CMEs and their interplanetary CMEs (ICMEs) are rotated, reconfigured, deformed, deflected, decelerated and disguised during their journey through the solar wind. This study then leads to consideration of how structures originating in coronal eruptions can be connected to their far removed interplanetary counterparts. Given that ICMEs are the drivers of most geomagnetic storms (and the sole driver of extreme storms), this work provides a guide to the processes that must be considered in making space weather forecasts from remote observations of the corona.Peer reviewe