3,805 research outputs found

    Finite size effects near the onset of the oscillatory instability

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    A system of two complex Ginzburg - Landau equations is considered that applies at the onset of the oscillatory instability in spatial domains whose size is large (but finite) in one direction; the dependent variables are the slowly modulated complex amplitudes of two counterpropagating wavetrains. In order to obtain a well posed problem, four boundary conditions must be imposed at the boundaries. Two of them were already known, and the other two are first derived in this paper. In the generic case when the group velocity is of order unity, the resulting problem has terms that are not of the same order of magnitude. This fact allows us to consider two distinguished limits and to derive two associated (simpler) sub-models, that are briefly discussed. Our results predict quite a rich variety of complex dynamics that is due to both the modulational instability and finite size effects

    PGI12 DOSE VARIATIONS WITH ADALIMUMAB AND INFLIXIMAB IN THE TREATMENT OF CROHN'S DISEASE: A CANADIAN ASSESSMENT

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    Principal Component Analysis of the Time- and Position-Dependent Point Spread Function of the Advanced Camera for Surveys

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    We describe the time- and position-dependent point spread function (PSF) variation of the Wide Field Channel (WFC) of the Advanced Camera for Surveys (ACS) with the principal component analysis (PCA) technique. The time-dependent change is caused by the temporal variation of the HSTHST focus whereas the position-dependent PSF variation in ACS/WFC at a given focus is mainly the result of changes in aberrations and charge diffusion across the detector, which appear as position-dependent changes in elongation of the astigmatic core and blurring of the PSF, respectively. Using >400 archival images of star cluster fields, we construct a ACS PSF library covering diverse environments of the HSTHST observations (e.g., focus values). We find that interpolation of a small number (∌20\sim20) of principal components or ``eigen-PSFs'' per exposure can robustly reproduce the observed variation of the ellipticity and size of the PSF. Our primary interest in this investigation is the application of this PSF library to precision weak-lensing analyses, where accurate knowledge of the instrument's PSF is crucial. However, the high-fidelity of the model judged from the nice agreement with observed PSFs suggests that the model is potentially also useful in other applications such as crowded field stellar photometry, galaxy profile fitting, AGN studies, etc., which similarly demand a fair knowledge of the PSFs at objects' locations. Our PSF models, applicable to any WFC image rectified with the Lanczos3 kernel, are publicly available.Comment: Accepted to PASP. To appear in December issue. Figures are degraded to meet the size limit. High-resolution version can be downloaded at http://acs.pha.jhu.edu/~mkjee/acs_psf/acspsf.pd

    CARTE: An Observation Station to Regulate Activity in a Learning Context

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    This chapter discusses the introduction of a new concept called "regulation" into a use model, which is part of a theoretical observation model called trace-based system (TBS). This concept defines a retroaction mechanism in an observation station. We present the results of experiments, in a learning context, with a prototype observation station called Collection, activity Analysis and Regulation based on Traces Enriched (CARTE)

    Expression of Hepatitis B Virus Surface Antigen Containing Y100C Variant Frequently Detected in Occult HBV Infection

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    Small hepatitis B virus surface protein (S-HBsAg) variant Y100C has been associated with HBsAg-negative phenotype. To determine whether Y100C substitution yields impaired HBsAg or small amounts of HBsAg that may reduce HBsAg detection by commercial anti-HBsAg antibodies, two eukaryotic expression plasmids, one containing a wild-type S and the other an S gene from a Y100C variant, were constructed and their levels of HBsAg compared by ELISA after transfection of HuH7 cells. Unexpectedly, the extracellular HBsAg levels detected with Y100C plasmid were higher than those observed with the wild-type plasmid, but without statistical significance. We concluded that the Y100C substitution alone did not play a role in reducing HBsAg amounts or HBsAg affinity by commercial ELISA assay. Further studies on in vitro replication fitness with the complete genome of HBV isolates displaying or not Y100C substitution may elucidate whether this mutation affects HBV replication and consequently HBsAg production

    Instability of two interacting, quasi-monochromatic waves in shallow water

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    We study the nonlinear interactions of waves with a doubled-peaked power spectrum in shallow water. The starting point is the prototypical equation for nonlinear uni-directional waves in shallow water, i.e. the Korteweg de Vries equation. Using a multiple-scale technique two defocusing coupled Nonlinear Schr\"odinger equations are derived. We show analytically that plane wave solutions of such a system can be unstable to small perturbations. This surprising result suggests the existence of a new energy exchange mechanism which could influence the behaviour of ocean waves in shallow water.Comment: 4 pages, 2 figure

    On maximum entropy priors and a most likely likelihood in auditing

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    There are two basic questions auditors and accountants must consider when developing test and estimation applications using Bayes' Theorem: What prior probability function should be used and what likelihood function should be used. In this paper we propose to use a maximum entropy prior probability function MEP with the most likely likelihood function MLL in the Quasi-Bayesian QB model introduced by McCray (1984). It is defined on an adequate parameter. Thus procedure only needs an expected value of Ξ0 known (in this paper the expected tainting) to obtain a MEP all an auditor or accountant need to supply are the range, as with any other prior, and the expected tainting, Ξ0. We will see some practical applications of the methodology proposed about internal control evaluation in auditing

    Experimental study of a liquid Xenon PET prototype module

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    A detector using liquid Xenon in the scintillation mode is studied for Positron Emission Tomography (PET). The specific design aims at taking full advantage of the liquid Xenon properties. It does feature a promising insensitive to any parallax effect. This work reports on the performances of the first LXe prototype module, equipped with a position sensitive PMT operating in the VUV range (178 nm).Comment: Proc. of the 7th International Workshops on Radiation Imaging Detectors (IWORID-7), Grenoble, France 4-7 July 200

    NIKEL: Electronics and data acquisition for kilopixels kinetic inductance camera

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    A prototype of digital frequency multiplexing electronics allowing the real time monitoring of microwave kinetic inductance detector (MKIDs) arrays for mm-wave astronomy has been developed. Thanks to the frequency multiplexing, it can monitor simultaneously 400 pixels over a 500 MHz bandwidth and requires only two coaxial cables for instrumenting such a large array. The chosen solution and the performances achieved are presented in this paper.Comment: 21 pages, 14 figure

    Galaxy clusters in the CFHTLS. First matched filter candidate catalogue of the Deep fields

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    We apply a matched-filter cluster detection algorithm to the Canada-France-Hawaii Telescope Legacy Survey (CFHTLS) i-band data for the Deep-1, Deep-2, Deep-3 and Deep-4 fields covering a total of 4square degrees. To test the implemented procedure we carry out simulations for assessing the frequency of noise peaks as well as estimate the recovery efficiency. We estimate that up to z~0.7 the catalogue is essentially complete for clusters of richness class R>~1. The recovered redshifts are in general overestimated by dz=0.1 with a scatter of sigma_dz~0.1, except at redshifts z>~1 where the estimated redshifts are systematically underestimated. The constructed cluster candidate catalogue contains 162 detections over an effective area of 3.112 square degrees corresponding to a density of ~52.1 per square degree. The median estimated redshift of the candidates is z=0.6. The estimated noise frequency is 16.9+-5.4 detections per square degree. From visual inspection we identify systems that show a clear concentration of galaxies with similar colour. These systems have a density of ~20 per square degree
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