Lingulodinium machaerophorum expansion over the last centuries in the Caspian Sea reflects global warming

This article is made available through the Brunel Open Access Publishing Fund. Copyright @ Author(s) 2012. This work is distributed under the Creative Commons Attribution 3.0 License.We analysed dinoflagellate cyst assemblages in four short sediment cores, two of them dated by radionuclides, taken in the south basin of the Caspian Sea. The interpretation of the four sequences is supported by a collection of 27 lagoonal or marine surface sediment samples. A sharp increase in the biomass of the dinocyst occurs after 1967, especially owing to Lingulodinium machaerophorum. Considering nine other cores covering parts or the whole of Holocene, this species started to develop in the Caspian Sea only during the last three millennia. By analysing instrumental data and collating existing reconstructions of sea level changes over the last few millennia, we show that the main forcing of the increase of L. machaerophorum percentages and of the recent dinocyst abundance is global climate change, especially sea surface temperature increase. Sea level fluctuations likely have a minor impact. We argue that the Caspian Sea has entered the Anthropocene

Many pion decays of rho(770) and omega(782) mesons in chiral theory

The decays rho(770) to 4 pi and omega(782) to 5pi are considered in detail in the approach based on the Weinberg Lagrangian obtained upon the nonlinear realization of chiral symmetry, added with the term induced by the anomalous Lagrangian of Wess and Zumino. The partial widths and excitation curves of the decays rho^0 to 2 pi^+ 2 pi^-, pi^+ pi^- 2 pi^0, rho^{+-} to 2 pi^{+-} pi^{-+} pi^0, rho^(+-} to pi^(+-} 3 pi^0 are evaluated for e^+e^- annihilation, photoproduction and tau lepton decays. The results of calculations are compared with the recent CMD-2 data on the decay rho^0 to 2 pi^+ 2 pi^- observed in e^+e^- annihilation. The omega to 5 pi decay widths and excitation curves in e^+e^- annihilation are obtained. The angular distributions for various combinations of the final pions in the decays rho to 4 pi and omega to 5 pi are written. The perspectives of the experimental study of the above decays in e^+e^- annihilation, tau lepton decays and photoproduction are discussed.Comment: Revtex, 32 pages including 11 ps figures. Replaced to fit the version published in Phys. Rev. D. Material rearranged, clarifying remarks and references added, typos fixe

Usage Pattern Recognition in Student Activities

Proceedings of: 6th European Conference of Technology Enhanced Learning, EC-TEL 2011, Palermo, Italy, September 20-23, 2011.This paper presents an approach of collecting contextualized attention metadata combined from inside as well as outside a LMS and analyzing them to create feedback about the student activities for the teaching staff. Two types of analyses were run on the collected data: first, key actions were extracted to identify usage patterns and tendencies throughout the whole course and then usage statistics and patterns were identified for some key actions in more detail. Results of both analyses were visualized and presented to the teaching staff for evaluation.The research leading to these results has received funding from the European Community’s Seventh Framework Programme (FP7/2007- 2013) under grant agreement no 231396 (ROLE project). Work was also partially funded by the Learn3 project (TIN2008-05163/TSI), the eMadrid project (S2009/TIC-1650), and the Acción Integrada DE2009-0051

Data-based analysis of speech and gesture: the Bielefeld Speech and Gesture Alignment corpus (SaGA) and its applications

Lücking A, Bergmann K, Hahn F, Kopp S, Rieser H. Data-based analysis of speech and gesture: the Bielefeld Speech and Gesture Alignment corpus (SaGA) and its applications. Journal on Multimodal User Interfaces. 2013;7(1-2):5-18.Communicating face-to-face, interlocutors frequently produce multimodal meaning packages consisting of speech and accompanying gestures. We discuss a systematically annotated speech and gesture corpus consisting of 25 route-and-landmark-description dialogues, the Bielefeld Speech and Gesture Alignment corpus (SaGA), collected in experimental face-to-face settings. We first describe the primary and secondary data of the corpus and its reliability assessment. Then we go into some of the projects carried out using SaGA demonstrating the wide range of its usability: on the empirical side, there is work on gesture typology, individual and contextual parameters influencing gesture production and gestures’ functions for dialogue structure. Speech-gesture interfaces have been established extending unification-based grammars. In addition, the development of a computational model of speech-gesture alignment and its implementation constitutes a research line we focus on

Distinct regulatory effects of myeloid cell and endothelial cell Nox2 on blood pressure

Background -Hypertension due to increased renin angiotensin system (RAS) activation is associated with elevated reactive oxygen species (ROS) production. Previous studies implicate NADPH oxidase (Nox) proteins as important ROS sources during RAS activation, with different Nox isoforms being potentially involved. Among these, Nox2 is expressed in multiple cell types including endothelial cells, fibroblasts, immune cells and microglia. Blood pressure (BP) is regulated at central nervous system, renal and vascular levels but the cell-specific role of Nox2 in BP regulation is unknown. Methods -We generated a novel mouse model with a Floxed Nox2 gene and used Tie2-Cre, LysM Cre or Cdh5-CreERT2 driver lines to develop cell-specific models of Nox2 perturbation to investigate its role in BP regulation. Results -Unexpectedly, Nox2 deletion in myeloid but not endothelial cells resulted in a significant reduction in basal BP. Tie2-CreNox2 knockout (KO) mice (in which Nox2 was deficient in both endothelial cells and myeloid cells) and LysM Cre Nox2KO mice (in which Nox2 was deficient in myeloid cells) both had significantly lower BP than littermate controls whereas basal BP was unaltered in Cdh5-CreERT2 Nox2 KO mice (in which Nox2 is deficient only in endothelial cells). The lower BP was attributable to an increased NO bioavailability which dynamically dilated resistance vessels in vivo under basal conditions, without change in renal function. Myeloid-specific Nox2 deletion had no effect on angiotensin II-induced hypertension which, however, was blunted in Tie2-CreNox2KO mice along with preservation of endothelium-dependent relaxation during angiotensin II stimulation. Conclusions -We identify a hitherto unrecognized modulation of basal BP by myeloid cell Nox2 whereas endothelial cell Nox2 regulates angiotensin II-induced hypertension. These results identify distinct cell-specific roles for Nox2 in BP regulation

Holocene Landscape Dynamics and Long-term Population Trends in the Levant

This paper explores long-term trends in human population and vegetation change in the Levant from the early to the late Holocene in order to assess when and how human impact has shaped the region’s landscapes over the millennia. To do so, we employed multiple proxies and compared archaeological, pollen and palaeoclimate data within a multi-scalar approach in order to assess how Holocene landscape dynamics change at different geographical scales. We based our analysis on 14 fossil pollen sequences and applied a hierarchical agglomerative clustering and community classification in order to define groups of vegetation types (e.g. grassland, wetland, woodland, etc.). Human impact on the landscape has been assessed by the analysis of pollen indicator groups. Archaeological settlement data and Summed Probability Distribution (SPD) of radiocarbon dates have been used to reconstruct long-term demographic trends. In this study, for the first time, the evolution of the human population is estimated statistically and compared with environmental proxies for assessing the interplay of biotic and abiotic factors in shaping the Holocene landscapes in the Levant

On Heads and Coordination in Valence Acquisition

Abstract. The aim of this paper is to present the design of a partial syntactic annotation of the IPI PAN Corpus of Polish [22] and the cor-responding extension of the corpus search engine Poliqarp [25,12] devel-oped at the Institue of Computer Science PAS and currently employed in Polish and Portuguese corpora projects. In particular, we will argue for the need to distinguish between, and represent both, syntactic and se-mantic heads, and we will sketch the representation of coordination, the area traditionally controversial both in theoretical and in computational linguistics. The annotation is designed in a way intended to maximise the usefulness of the resulting corpus for the task of automatic valence acquisition

The decays omega(782), phi(1020) to 5 pi in the hidden local symmetry approach

The decays omega -> 2pi^+ 2pi^- pi^0 and omega -> pi^+ pi^- 3pi^0 are reconsidered in the hidden local symmetry approach (HLS) added with the anomalous terms. The decay amplitudes are analyzed in detail, paying the special attention to the Adler condition of vanishing the whole amplitude at vanishing momentum of any final pion. Combining the Okubo-Zweig-Iizuka (OZI) rule applied to the five pion final state, with the Adler condition, we calculate also the phi -> 2pi^+ 2pi^-pi^0 and phi -> pi^+ pi^- 3pi^0 decay amplitudes. The partial widths of the above decays are evaluated, and the excitation curves in e^+e^- annihilation are obtained, assuming reasonable particular relations among the parameters characterizing the anomalous terms of the HLS Lagrangian. The evaluated branching ratios B(phi -> pi^+ pi^- 3pi^0)~2x10^{-7} and B(phi -> 2pi^+ 2pi^- pi^0)~7x10^{-7} are such that with the luminosity L=500 pb^{-1} attained at DAFNE phi factory, one may already possess about 1685 events of the decays phi -> 5pi.Comment: 15 pages text, 12 pages of figures. Typos corrected, clarifying remarks added. Accepted for publication in Phys.Rev.

Neuronal intranuclear inclusion disease is genetically heterogeneous

Neuronal intranuclear inclusion disease (NIID) is a clinically heterogeneous neurodegenerative condition characterized by pathological intranuclear eosinophilic inclusions. A CGG repeat expansion in NOTCH2NLC was recently identified to be associated with NIID in patients of Japanese descent. We screened pathologically confirmed European NIID, cases of neurodegenerative disease with intranuclear inclusions and applied in silico-based screening using whole-genome sequencing data from 20 536 participants in the 100 000 Genomes Project. We identified a single European case harbouring the pathogenic repeat expansion with a distinct haplotype structure. Thus, we propose new diagnostic criteria as European NIID represents a distinct disease entity from East Asian cases

Usefulness and acceptability of a standardised orientation and mobility training for partially-sighted older adults using an identification cane

<p>Abstract</p> <p>Background</p> <p>Orientation and mobility (O&M) training in using an identification (ID) cane is provided to partially-sighted older adults to facilitate independent functioning and participation in the community. Recently, a protocolised standardised O&M-training in the use of the ID cane was developed in The Netherlands. The purpose of this study is to assess the usefulness and acceptability of both the standardised training and the regular training for participants and O&M-trainers in a randomised controlled trial (NCT00946062).</p> <p>Methods</p> <p>The standardised O&M-training consists of two structured face-to-face sessions and one telephone follow-up, in which, in addition to the regular training, self-management and behavioural change techniques are applied. Questionnaires and interviews were used to collect data on the training’s usefulness, e.g. the population reached, self-reported benefits or achievements, and acceptability, e.g. the performance of the intervention according to protocol and participants’ exposure to and engagement in the training.</p> <p>Results</p> <p>Data was collected from 29 O&M-trainers and 68 participants. Regarding the self-reported benefits, outcomes were comparable for the standardised training and the regular training according the trainers and participants e.g., about 85% of the participants in both groups experienced benefits of the cane and about 70% gained confidence in their capabilities. Participants were actively involved in the standardised training. Nearly 40% of the participants in the standardised training group was not exposed to the training according to protocol regarding the number of sessions scheduled and several intervention elements, such as action planning and contracting.</p> <p>Conclusions</p> <p>The standardised and regular O&M-training showed to be useful and mostly acceptable for the partially-sighted older adults and trainers. Yet, a concern is the deviation from the protocol of the standardised O&M-training by the O&M-trainers regarding distinguishing elements such as action planning. Overall, participants appreciated both trainings and reported benefit.</p