1,961 research outputs found
Inclusion of [H3PW12O40] and [H4SiW12O40] into a silica gel matrix via "sol-gel" methodology
Indexación: Web of Science; Scopus.Here we report the inclusion of two Keggin Polyoxometalates (POMs), [H3PW12O40] and [H4SiW12O40], into silica gels by integrating them during the preparation of the SiO2 matrix via "sol-gel" methods. Aerogels were produced by supercritical drying of the wet gels impregnated with the POMs, and lyogels were obtained by means of a lyophilization process. These materials were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM), Fourier transformed infrared (FT-IR) spectroscopy and thermoanalytical techniques (TGA-DSC). We found that a large fraction of POMs are lost during the aging time, and solvent exchange for lyophilization. However the thermal stability of the bare matrix is modified by the inclusion of POMs. Some aggregates with a high content of POMs were found via SEM-EDX.http://ref.scielo.org/3fg9t
Estrategía didáctica para transformar las concepciones de los niños preescolares sobre seres vivos
Este trabajo describe cuáles son las ideas previas que los niños preescolares poseen en relación al concepto de ser vivo y cómo a través de la aplicación de una estrategia didáctica fundamentada en un marco constructivista se busca el cambio conceptual y la transformación de éstas a través de la modelización, metacognición y analogías. Algunos resultados son presentados
On the dynamics of a quadratic scalar field potential
We review the attractor properties of the simplest chaotic model of
inflation, in which a minimally coupled scalar field is endowed with a
quadratic scalar potential. The equations of motion in a flat
Friedmann-Robertson-Walker universe are written as an autonomous system of
equations, and the solutions of physical interest appear as critical points.
This new formalism is then applied to the study of inflation dynamics, in which
we can go beyond the known slow-roll formalism of inflation.Comment: 14 pages, 6 eps figures, matches version to appear in IJMP
Estabilidad de pórticos 2D en régimen elastoplástico
AbstractThe evaluation of the maximum level of load that any 2D framed structure can undergo, before plastic collapse or buckling, is addressed in this paper. The analytical approach, based on a beam element with elastic behaviour except on its ends, uses an incremental approach to determine when changes appear due to plastic behaviour. When the combination of axial force and bending moment in any cross-section reaches the plastic function, that section is considered to yield suddenly and relative displacements can appear because of the yielding. The model includes the traditional plastic hinge, which only considers relative rotation due to the effect of the bending moment. The sequential loading and yielding reduces the stiffness and stability of the frame, which is computed and compared with the classic plastic methods of analysis
Unveiling the structure of the planetary nebula M 2-48: Kinematics and physical conditions
The kinematics and physical conditions of the bipolar planetary nebula M 2-48
are analysed from high and low dispersion long-slit spectra. Previous CCD
narrow-band optical observations have suggested that this nebula is mainly
formed by a pair of symmetric bow-shocks, an off-center semi-circular shell,
and an internal bipolar structure. The bipolar outflow has a complex structure,
characterised by a series of shocked regions located between the bright core
and the polar tips. There is an apparent kinematic discontinuity between the
bright bipolar core and the outer regions. The fragmented ring around the
bright bipolar region presents a low expansion velocity and could be associated
to ejection in the AGB-PN transition phase, although its nature remains
unclear. The chemical abundances of the central region are derived, showing
that M 2-48 is a Type I planetary nebula (PN)
Systematic identification of phenotypically enriched loci using a patient network of genomic disorders
Background
Network medicine is a promising new discipline that combines systems biology approaches and network science to understand the complexity of pathological phenotypes. Given the growing availability of personalized genomic and phenotypic profiles, network models offer a robust integrative framework for the analysis of "omics" data, allowing the characterization of the molecular aetiology of pathological processes underpinning genetic diseases.
Methods
Here we make use of patient genomic data to exploit different network-based analyses to study genetic and phenotypic relationships between individuals. For this method, we analyzed a dataset of structural variants and phenotypes for 6,564 patients from the DECIPHER database, which encompasses one of the most comprehensive collections of pathogenic Copy Number Variations (CNVs) and their associated ontology-controlled phenotypes. We developed a computational strategy that identifies clusters of patients in a synthetic patient network according to their genetic overlap and phenotype enrichments.
Results
Many of these clusters of patients represent new genotype-phenotype associations, suggesting the identification of newly discovered phenotypically enriched loci (indicative of potential novel syndromes) that are currently absent from reference genomic disorder databases such as ClinVar, OMIM or DECIPHER itself.
Conclusions
We provide a high-resolution map of pathogenic phenotypes associated with their respective significant genomic regions and a new powerful tool for diagnosis of currently uncharacterized mutations leading to deleterious phenotypes and syndromes
Hydrodynamic modelling and operational oceanography for oil-spill events in the andalusian coast: a real case study during the fedra accident (October 2008)
Peer Reviewe
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