633 research outputs found

    Narrow Linewidth 780 nm Distributed Feedback Lasers for Cold Atom Quantum Technology

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    Cold atom quantum technology systems have a wide range of potential applications which includes atomic clocks, rotational sensors, inertial sensors, quantum navigators, magnetometers and gravimeters. The UK Quantum Technology Hub in Sensors and Metrology has the aim of developing miniature cold atom systems using an approach similar to that pioneered by the chip scale atomic clock where microfabricated vacuum chambers have atomic transitions excited and probed by lasers. Whilst narrow linewidth Ti:Sa and external cavity diode lasers have been required for cooling and control, such lasers are too large, power hungry and expensive for future miniature cold atom systems. Here we demonstrate 1 mm long 780.24 nm GaAs/AlGaAs distributed feedback (DFB) lasers aimed at 87Rb cold atom systems operating at 20 ËšC with over 50 mW of power and side-mode suppression ratios of 46 dB using sidewall gratings and no regrowth. Rb spectroscopy is used to demonstrate linewidths below the required 6.07 MHz natural linewidth of the 87Rb D2 optical transition used for cooling. Initial packaged fibre-coupled devices demonstrate lifetimes greater than 200 hours. We also investigate the use of integrated semiconductor amplifiers (SOAs) and longer devices to further reduce the linewidths well below 1 MHz. A range of options to control the populations of electrons in the hyperfine split energy levels spaced by 3.417 GHz are examined. Two integrated lasers, integrated electro-absorption modulators (EAMs) and the direct modulation of a single DFB laser approaches are investigated and we will discuss which is best suited to integrated cold atom systems

    Time resolved observation of resonant and non-resonant contributions to the nonlinear susceptibility χ(3)

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    The resonant and nonresonant part of χ(3) are distinguished by their different time behavior. The medium is coherently excited by two picosecond light pulses of defined frequency difference and the state of the system is monitored by a third properly delayed probe pulse. Results are presented on neat liquids of carbontetrachloride and cyclohexane and on the mixture of CCl4: C6H12

    Conflict of interest: A tenacious ethical dilemma in public health policy, not only in clinical practice/research

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    In addition to the ethical practice of individual health professionals, bioethical debate about conflict of interest (CoI) must include theinstitutional ethics of public policy-making, as failure to establish independence from powerful stakeholder influence may pervert publichealth goals. All involved in public policy processes are accountable for CoI, including experts, scientists, professionals, industry and government officials. The liquor industry in South Africa is presented as a case study. Generic principles of how to identify, manage and address CoI are discussed. We propose that health professionals and policy makers should avoid partnering with industries that are harmful to health. Regarding institutional CoI, we recommend that there should be effective policies, procedures and processes for governing public-private joint ventures with such industries. These include arms-length funding, maintaining the balance between contesting vested interests, and full disclosure of the identity and affiliations of all participants in structures and reports pertaining to public policy-making

    Bound and free waves in non-collinear second harmonic generation

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    We analyze the relationship between the bound and the free waves in the noncollinear SHG scheme, along with the vectorial conservation law for the different components arising when there are two pump beams impinging on the sample with two different incidence angles. The generated power is systematically investigated, by varying the polarization state of both fundamental beams, while absorption is included via the Herman and Hayden correction terms. The theoretical simulations, obtained for samples which are some coherence length thick show that the resulting polarization mapping is an useful tool to put in evidence the interference between bound and free waves, as well as the effect of absorption on the interference patternComment: 10 pages, 7 figure. to be published on Optics Expres

    Repetitive low intensity magnetic field stimulation in a neuronal cell line: a metabolomics study

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    Low intensity repetitive magnetic stimulation of neural tissue modulates neuronal excitability and has promising therapeutic potential in the treatment of neurological disorders. However, the underpinning cellular and biochemical mechanisms remain poorly understood. This study investigates the behavioural effects of low intensity repetitive magnetic stimulation (LI-rMS) at a cellular and biochemical level. We delivered LI-rMS (10 mT) at 1 Hz and 10 Hz to B50 rat neuroblastoma cells in vitro for 10 minutes and measured levels of selected metabolites immediately after stimulation. LI-rMS at both frequencies depleted selected tricarboxylic acid (TCA) cycle metabolites without affecting the main energy supplies. Furthermore, LI-rMS effects were frequency-specific with 1 Hz stimulation having stronger effects than 10 Hz. The observed depletion of metabolites suggested that higher spontaneous activity may have led to an increase in GABA release. Although the absence of organised neural circuits and other cellular contributors (e.g., excitatory neurons and glia) in the B50 cell line limits the degree to which our results can be extrapolated to the human brain, the changes we describe provide novel insights into how LI-rMS modulates neural tissue

    Examination of the temporal variation of peptide content in decomposition fluid under controlled conditions using pigs as human substitutes

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    We report the preliminary observations of the peptide content of decomposition fluid produced under controlled laboratory conditions and in the absence of a soil matrix. Four domestic pig (Sus scrofa domesticus) cadavers were used to model human decomposition over a four-week trial period; physical characteristics were recorded and the peptide components of decomposition fluid was analysed using high performance liquid chromatography-time of flight mass spectrometry. Preliminary data analysis indicated that a range of peptides were consistently detected across the course of the trial period and 27 of these were common to all four cadavers; 22 originating from haemoglobin. The peptides associated with haemoglobin subunit alpha and beta displayed a breakdown pattern that remained consistent for all cadavers for the duration of the trial. Though identification of peptides during decomposition has potential for estimating the time since death, quantification of selected peptides is likely to be essential to identify time-dependent trends

    Conflict of interest: A tenacious ethical dilemma in public health policy not only in clinical practice/research

    Get PDF
    In addition to the ethical practice of individual health professionals, bioethical debate about conflict of interest (CoI) must include the institutional ethics of public policy-making, as failure to establish independence from powerful stakeholder influence may pervert public health goals. All involved in public policy processes are accountable for CoI, including experts, scientists, professionals, industry and government officials. The liquor industry in South Africa is presented as a case study. Generic principles of how to identify, manage and address CoI are discussed. We propose that health professionals and policy makers should avoid partnering with industries that are harmful to health. Regarding institutional CoI, we recommend that there should be effective policies, procedures and processes for governing public-private joint ventures with such industries. These include arms-length funding, maintaining the balance between contesting vested interests, and full disclosure of the identity and affiliations of all participants in structures and reports pertaining to public policy-making

    Harmonic generation and energy transport in dielectric and semiconductors at visible and UV wavelengths: the case of GaP

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    We study inhibition of absorption, transparency, energy and momentum transport of the inhomogeneous component of harmonic pulses in dielectrics and semiconductors, at visible and UV wavelengths, focusing on materials like GaP. In these spectral regions GaP is characterized by large absorption, metallic behavior or a combination of both. We show that phase locking causes the generated inhomogeneous signals to propagate through a bulk metallic medium without being absorbed, that is occurs even in centrosymmetric materials via the magnetic Lorentz force, and that the transport of energy and momentum is quite peculiar and seemingly anomalous. These results make it clear that there are new opportunities in ultrafast nonlinear optics and nano-plasmonics in new wavelength ranges.Comment: 16 pages, 5 figures, 1 vide
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