The H I angular momentum-mass relation

We study the relationship between the H I specific angular momentum ($\rm j_{g}$) and the H I mass ($\rm M_{g}$) for a sample of galaxies with well-measured H I rotation curves. We find that the relation is well described by an unbroken power law $\rm j_{g}$ ∝ $\rm M_{g}$α over the entire mass range (107-1010.5 M⊙), with α = 0.89 ± 0.05 (scatter 0.18 dex). This is in reasonable agreement with models which assume that evolutionary processes maintain H I discs in a marginally stable state. The slope we observe is also significantly different from both the j ∝ M2/3 relation expected for dark matter haloes from tidal torquing models and the observed slope of the specific angular momentum-mass relation for the stellar component of disc galaxies. Our sample includes two H I-bearing ultra-diffuse galaxies, and we find that their angular momentum follows the same relation as other galaxies. The only discrepant galaxies in our sample are early-type galaxies with large rotating H I discs, which are found to have significantly higher angular momentum than expected from the power-law relation. The H I discs of all these early-type galaxies are misaligned or counter-rotating with respect to the stellar discs, consistent with the gas being recently accreted. We speculate that late-stage wet mergers, as well as cold flows play a dominant role in determining the kinematics of the baryonic component of galaxies as suggested by recent numerical simulations

Towards sustainable training in essential computing research skills in the Netherlands

Life science research increasingly depends on computational skills that enable efficient work with large complex datasets. Unfortunately, formal curricula often lack training in this area. There is a need for specialised training that includes topics like shell scripting, basic programming skills in R or Python, data handling, reproducible computational research and open science

MIGHTEE-HI: the HI Size-Mass relation over the last billion years

We present the observed HI size-mass relation of $204$ galaxies from the MIGHTEE Survey Early Science data. The high sensitivity of MeerKAT allows us to detect galaxies spanning more than 4 orders of magnitude in HI mass, ranging from dwarf galaxies to massive spirals, and including all morphological types. This is the first time the relation has been explored on a blind homogeneous data set which extends over a previously unexplored redshift range of $0 < z < 0.084$, i.e. a period of around one billion years in cosmic time. The sample follows the same tight logarithmic relation derived from previous work, between the diameter ($D_{\rm HI}$) and the mass ($M_{\rm HI}$) of HI discs. We measure a slope of $0.501\pm 0.008$, an intercept of $-3.252^{+0.073}_{-0.074}$, and an observed scatter of $0.057$ dex. For the first time, we quantify the intrinsic scatter of $0.054 \pm 0.003$ dex (${\sim} 10 \%$), which provides a constraint for cosmological simulations of galaxy formation and evolution. We derive the relation as a function of galaxy type and find that their intrinsic scatters and slopes are consistent within the errors. We also calculate the $D_{\rm HI} - M_{\rm HI}$ relation for two redshift bins and do not find any evidence for evolution with redshift. These results suggest that over a period of one billion years in lookback time, galaxy discs have not undergone significant evolution in their gas distribution and mean surface mass density, indicating a lack of dependence on both morphological type and redshift.Comment: 10 pages, 5 figures, accepted for publication in MNRA

MIGHTEE-HI: The first MeerKAT HI mass function from an untargeted interferometric survey

We present the first measurement of the HI mass function (HIMF) using data from MeerKAT, based on 276 direct detections from the MIGHTEE Survey Early Science data covering a period of approximately a billion years ($0 \leq z \leq 0.084$). This is the first HIMF measured using interferometric data over non-group or cluster field, i.e. a deep blank field. We constrain the parameters of the Schechter function which describes the HIMF with two different methods: $1/\rm V_{\rm max}$ and Modified Maximum Likelihood (MML). We find a low-mass slope $\alpha=-1.29^{+0.37}_{-0.26}$, `knee' mass $\log_{10}(M_{*}/{\rm M_{\odot}}) = 10.07^{+0.24}_{-0.24}$ and normalisation $\log_{10}(\phi_{*}/\rm Mpc^{-3})=-2.34^{+0.32}_{-0.36}$ ($H_0 = 67.4$ kms$^{-1}$ Mpc$^{-1}$) for $1/\rm V_{\rm max}$ and $\alpha=-1.44^{+0.13}_{-0.10}$, `knee' mass $\log_{10}(M_{*}/{\rm M_{\odot}}) = 10.22^{+0.10}_{-0.13}$ and normalisation $\log_{10}(\phi_{*}/\rm Mpc^{-3})=-2.52^{+0.19}_{-0.14}$ for MML. When using $1/\rm V_{\rm max}$ we find both the low-mass slope and `knee' mass to be consistent within $1\sigma$ with previous studies based on single-dish surveys. The cosmological mass density of HI is found to be slightly larger than previously reported: $\Omega_{\rm HI}=5.46^{+0.94}_{-0.99} \times 10^{-4}h^{-1}_{67.4}$ from $1/\rm V_{\rm max}$ and $\Omega_{\rm HI}=6.31^{+0.31}_{-0.31} \times 10^{-4}h^{-1}_{67.4}$ from MML but consistent within the uncertainties. We find no evidence for evolution of the HIMF over the last billion years.Comment: 13 pages, 9 figures, accepted for publication in MNRA

MIGHTEE-\HI: Possible interactions with the galaxy NGC~895

The transformation and evolution of a galaxy is strongly influenced by interactions with its environment. Neutral hydrogen (\HI) is an excellent way to trace these interactions. Here, we present \HI\ observations of the spiral galaxy NGC~895, which was previously thought to be isolated. High-sensitivity \HI\ observations from the MeerKAT large survey project MIGHTEE reveal possible interaction features, such as extended spiral arms, and the two newly discovered \HI\ companions, that drive us to change the narrative that it is an isolated galaxy. We combine these observations with deep optical images from the Hyper Suprime Camera to show an absence of tidal debris between NGC 895 and its companions. We do find an excess of light in the outer parts of the companion galaxy MGTH$\_$J022138.1-052631 which could be an indication of external perturbation and thus possible sign of interactions. Our analysis shows that NGC~895 is an actively star-forming galaxy with a SFR of $\mathrm{1.75 \pm 0.09 [M_{\odot}/yr]}$, a value typical for high stellar mass galaxies on the star forming main sequence. It is reasonable to state that different mechanisms may have contributed to the observed features in NGC~895 and this emphasizes the need to revisit the target with more detailed observations. Our work shows the high potential and synergy of using state-of-the-art data in both \HI\ and optical to reveal a more complete picture of galaxy environments.Comment: 14 pages, 10 figures. Accepted for publication in MNRA

Symmorphosis through dietary regulation: a combinatorial role for proteolysis, autophagy and protein synthesis in normalising muscle metabolism and function of hypertrophic mice after acute starvation

Animals are imbued with adaptive mechanisms spanning from the tissue/organ to the cellular scale which insure that processes of homeostasis are preserved in the landscape of size change. However we and others have postulated that the degree of adaptation is limited and that once outside the normal levels of size fluctuations, cells and tissues function in an aberant manner. In this study we examine the function of muscle in the myostatin null mouse which is an excellent model for hypertrophy beyond levels of normal growth and consequeces of acute starvation to restore mass. We show that muscle growth is sustained through protein synthesis driven by Serum/Glucocorticoid Kinase 1 (SGK1) rather than Akt1. Furthermore our metabonomic profiling of hypertrophic muscle shows that carbon from nutrient sources is being channelled for the production of biomass rather than ATP production. However the muscle displays elevated levels of autophagy and decreased levels of muscle tension. We demonstrate the myostatin null muscle is acutely sensitive to changes in diet and activates both the proteolytic and autophagy programmes and shutting down protein synthesis more extensively than is the case for wild-types. Poignantly we show that acute starvation which is detrimental to wild-type animals is beneficial in terms of metabolism and muscle function in the myostatin null mice by normalising tension production

MIGHTEE-Hi: Evolution of Hi Scaling Relations of Star-forming Galaxies at z &lt; 0.5*

We present the first measurements of H I galaxy scaling relations from a blind survey at z > 0.15. We perform spectral stacking of 9023 spectra of star-forming galaxies undetected in H I at 0.23 < z < 0.49, extracted from MIGHTEE-H I Early Science data cubes, acquired with the MeerKAT radio telescope. We stack galaxies in bins of galaxy properties (stellar mass M *, star formation rateSFR, and specific star formation rate sSFR, with sSFR ≡ M */SFR), obtaining ≳5σ detections in most cases, the strongest H I-stacking detections to date in this redshift range. With these detections, we are able to measure scaling relations in the probed redshift interval, finding evidence for a moderate evolution from the median redshift of our sample z med ~ 0.37 to z ~ 0. In particular, low-M * galaxies ( {\mathrm{log}}_{10}({M}_{* }/{M}_{\odot })\sim 9 )experienceastrongHIdepletion( 0.5dexinlog10(MHI/M⊙) ), while massive galaxies ( {\mathrm{log}}_{10}({M}_{* }/{M}_{\odot })\sim 11$ ) keep their H I mass nearly unchanged. When looking at the star formation activity, highly star-forming galaxies evolve significantly in M H I (f H I, where f H I ≡ M H I/M *) at fixed SFR (sSFR), while at the lowest probed SFR (sSFR) the scaling relations show no evolution. These findings suggest a scenario in which low-M * galaxies have experienced a strong H I depletion during the last ~5 Gyr, while massive galaxies have undergone a significant H I replenishment through some accretion mechanism, possibly minor mergers. Interestingly, our results are in good agreement with the predictions of the SIMBA simulation. We conclude that this work sets novel important observational constraints on galaxy scaling relations

HIV infection and drugs of abuse: role of acute phase proteins

Background HIV infection and drugs of abuse such as methamphetamine (METH), cocaine, and alcohol use have been identified as risk factors for triggering inflammation. Acute phase proteins such as C-reactive protein (CRP) and serum amyloid A (SAA) are the biomarkers of inflammation. Hence, the interactive effect of drugs of abuse with acute phase proteins in HIV-positive subjects was investigated. Methods Plasma samples were utilized from 75 subjects with METH use, cocaine use, alcohol use, and HIV-positive alone and HIV-positive METH, cocaine, and alcohol users, and age-matched control subjects. The plasma CRP and SAA levels were measured by ELISA and western blot respectively and the CD4 counts were also measured. Results Observed results indicated that the CRP and SAA levels in HIV-positive subjects who are METH, cocaine and alcohol users were significantly higher when compared with either drugs of abuse or HIV-positive alone. The CD4 counts were also dramatically reduced in HIV-positive with drugs of abuse subjects compared with only HIV-positive subjects. Conclusions These results suggest that, in HIV-positive subjects, drugs of abuse increase the levels of CRP and SAA, which may impact on the HIV infection and disease progression

Agile Manifesto and Practices Selection for Tailoring Software Development: A Systematic Literature Review

peer reviewedAgile methods have been largely used for many years to provide developers with a flexible software development process leading to software quality improvement. To get the best results and eliminate unnecessary efforts, the development team should select the most appropriate methods and techniques. The fundamental core of an agile method has to be well-understood before deciding which parts of the method need to be adopted. We believe that the quickest way to do so is to understand the prescripts of the Agile Manifesto. Many researches have proposed different tailoring approaches based on the relation and straight-forward interpretation between each agile practice and agile values or principles. We however have observed that agile practitioners do not dedicate the necessary attention to the Agile Manifesto before adopting agile methods or practices and directly use them. It is because the importance of Agile Manifesto in tailoring context is not obvious enough to the community. This study aims at doing a systematic literature review on the existing case studies, to verify the relation between the Agile Manifesto and agile practice selection

Degradation behaviors and mechanisms of MoS2 crystals relevant to bioabsorbable electronics

Monolayer molybdenum disulfide (MoS2) exhibits unique semiconducting and bioresorption properties, giving this material enormous potential for electronic/biomedical applications, such as bioabsorbable electronics. In this regard, understanding the degradation performance of monolayer MoS2 in biofluids allows modulation of the properties and lifetime of related bioabsorbable devices and systems. Herein, the degradation behaviors and mechanisms of monolayer MoS2 crystals with different misorientation angles are explored. High-angle grain boundaries (HAGBs) biodegrade faster than low-angle grain boundaries (LAGBs), exhibiting degraded edges with wedge and zigzag shapes, respectively. Triangular pits that formed in the degraded grains have orientations opposite to those of the parent crystals, and these pits grow into larger pits laterally. These behaviors indicate that the degradation is induced and propagated based on intrinsic defects, such as grain boundaries and point defects, because of their high chemical reactivity due to lattice breakage and the formation of dangling bonds. High densities of dislocations and point defects lead to high chemical reactivity and faster degradation. The structural cause of MoS2 degradation is studied, and a feasible approach to study changes in the properties and lifetime of MoS2 by controlling the defect type and density is presented. The results can thus be used to promote the widespread use of two-dimensional materials in bioabsorption applications