96 research outputs found

    Awareness of Secondary School Students on Various Gender Perspective Programmes Conducted by the University of Dar Es Salam, Tanzania

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    A ZJER article on gender awareness amongst youths in Tanzania secondary schools.Gender imbalance is a common phenomenon in many educational institutions especially in developing countries. To overcome this imbalance, The University of Dar Es Salaam (UDSM) through its Gender Dimension Programme Committee (GDPC) has introduced gender-biased programmes with the aim of increasing female students’ enrolment at UDSM'. These programmes include Pre-entry Programme (PEP), Female Undergraduate Sponsorship Programme (FUSP) and Lower cut-off points. A cross section study was conducted in secondary schools in Dar Es Salaam region between August 2004 and July 2005 to investigate student awareness of these programmes. A total of276 students from 13 randomly selected secondary schools participated in the study. Self-administered questionnaires and checklists were used and the data were analysed by statistical software Epi Info 2002. The study showed that the majority of the students were familiar with the concept of ‘gender’ but could not specifically define what it was. They were not even aware that the University of Dar- Es-Salaam (UDSM) had gender intervention educational programmes in place. It is recommended that University gender programmes and general information on gender issues should be disseminated to society as a way of improving gender relations

    Chemical Composition and Bioactive Potential of Extracts from Diospyros capricornuta F. White against Aspergillus flavus and Aspergillus parasiticus

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    Diospyros capricornuta is an endemic species widely distributed along the coast of Tanzania that is used as food condiments and traditional medicine. The chemical compositions of Diospyros capricornuta leaves, stem-bark, and root-bark extracts; and their bioactive potentials against Aspergillus flavus and Aspergillus parasiticus were investigated. The leaves, stem-bark, and root-bark samples of D. capricornuta were extracted using Soxhlet apparatus and the resultant extracts were analyzed using Gas Chromatography-Mass Spectrometry (GC-MS). A total of 14 compounds were identified from the extracts, whereby 2,4-di-tert-butylphenol was the most abundant compound in all extracts. The growth and aflatoxin production inhibitions against A. flavus and A. parasiticus were determined via antifungal and antiaflatoxigenic bioassays of the extracts at the concentrations of 0.0, 62.5, 125.0, and 250.0 ”g/mL using a poisoned-food method. The High-Performance Liquid Chromatography (HPLC) technique was used to quantify the aflatoxins after bioassays to evaluate aflatoxin inhibitions. The stem-bark extracts at the highest dose of 250.0 ”g/mL inhibited aflatoxin production by A. flavus for over 99% and A. parasiticus for over 94%. Overall, the results show that the leaves, stem-bark, and root-bark extracts of D. capricornuta are potential inhibitors against A. flavus and A. parasiticus-the producers of aflatoxins. Keywords: Diospyros capricornuta; Growth inhibitions; Aflatoxin inhibitions; Aspergillus flavus; and Aspergillus parasiticus

    Occurrence of Aflatoxins in Maize and Maize Products from Selected Locations of Tanzania and the Effects of Cooking Preparation Processes on Toxin Levels

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    The production and storage of food crops in different countries is affected by aflatoxins contamination, which are known to be carcinogenic and mutagenic to human beings and domestic animals. This study investigated on the occurrence of aflatoxins in maize products and the effects of cooking preparation processes on their concentrations. The maize samples were collected from fields, farmers' stores and markets of selected locations in Tanzania (i.e., Kongwa and Njombe districts). Extracted samples were analyzed for aflatoxins using high performance liquid chromatography. The concentrations of aflatoxins in maize and maize products ranged from below detection limit to 9.99 ± 1.43 Όg/kg and 9.99 ± 0.14 Όg/kg for Njombe and Uwemba wards, respectively. Whereas those collected from Kibaigwa ward in Kongwa district ranged from 2.87 ± 0.02 Όg/kg to 10.26 ± 0.46 Όg/kg. The levels in cooked maize products were lower than the uncooked maize products. The mean concentrations of total aflatoxins in cooked maize products were 0.45 ± 0.05 Όg/kg for stiff porridge prepared from dehulled maize flour, 1.39 ± 0.02 Όg/kg for stiff porridge prepared from undehulled maize flour, and 0.584 ± 0.06 Όg/kg for maize meal (kande). Generally, the levels of aflatoxins were below the maximum acceptable limits set by WHO except for some samples from Kibaigwa market which were slightly above the set limits. Keywords: Aflatoxins; High Performance Liquid Chromatography; Maize; Fung

    Perceptions of surgeons on surgical antibiotic prophylaxis use at an urban tertiary hospital in Tanzania

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    Background: Surgical Site Infections are a major cause of morbidity and mortality among operated patients. In spite of the accessibility of universal and national guidelines for surgical prophylaxis, recent studies surveying the present routine of prophylaxis have demonstrated overutilization of a wide range antibacterial medication for a single patient. Few studies have shown qualitatively factors influencing this and perceptions of surgeons on surgical antibiotic prophylaxis use. Unfortunately, none of these studies have been done in Tanzania. Objective: To describe the perceptions of surgeons on surgical antibiotic prophylaxis use at an urban tertiary hospital. Methods: A qualitative study involving in-depth interviews with surgeons was conducted in English by the primary investigator. The interviews were audio-recorded and transcribed verbatim. Systematic text condensation by Malterud was used for data analysis. Findings: Fourteen surgeons and obstetrics and gynaecologists participated. Their perceptions were summarized into three main categories: Inadequate data to support practice; one who sees the patient decides the antibiotic prophylaxis; prolonged antibiotic use for fear of unknown. The participants perceived that choice of antibiotic should be based on local hospital data for bacterial resistance pattern, however the hospital guidelines and data for surgical site infection rates are unknown. Fear of getting infection and anticipating complications led to prolonged antibiotics use. Conclusion: The study provides an understanding of surgical antibiotic prophylaxis use and its implementation challenges. This was partly expressed by unavailability of local data and guidelines to enhance practice. To improve this, there is a need of guidelines that incorporates local resistance surveillance data and enhanced antibiotic stewardship programmes. A strong consideration should be placed into ways to combat the fears of surgeons for complications, as these significantly affect the current practise with use of surgical antibiotic prophylaxis

    Factors influencing adherence to antiretroviral therapy among people living with HIV in an urban and rural setting, Tanzania

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    Adherence is one of the most crucial determinants of treatment response to antiretroviral therapy (ART). An analytical cross-sectional study was conducted in 24 Care and Treatment Centres (CTC) in Dar es Salaam and Iringa regions in Tanzania. Data was collected using questionnaire and appointments records. A total of 943 patients attending at the care and treatment sites in Dar es Salaam and Iringa were recruited. Adherence based on keeping appointments and on four days recall was 65% and 70%, respectively. Adherence based on taking ART more than 95% of the time in one month was 83%. Satisfaction with health services, having treatment support, having knowledge on the use of ART, early presentation to CTC, and being on ART for more than one year, were associated with good adherence. Being in the urban region, using traditional medicine, medicine side effects and alcohol consumption problems negatively associated with adherence to ART.Keywords: Adherence barriers, antiretroviral therapy, HIV, Tanzania, rural, urba

    Priority setting for the implementation of artemisinin-based combination therapy policy in Tanzania: evaluation against the accountability for reasonableness framework

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    \ud Priority setting for artemisinin-based antimalarial drugs has become an integral part of malaria treatment policy change in malaria-endemic countries. Although these drugs are more efficacious, they are also more costly than the failing drugs. When Tanzania changed its National Malaria Treatment Policy in 2006, priority setting was an inevitable challenge. Artemether-lumefantrine was prioritised as the first-line drug for the management of uncomplicated malaria to be available at a subsidized price at public and faith-based healthcare facilities. This paper describes the priority-setting process, which involved the selection of a new first-line antimalarial drug in the implementation of artemisinin-based combination therapy policy. These descriptions were further evaluated against the four conditions of the accountability for easonableness framework. According to this framework, fair decisions must satisfy a set of publicity, relevance, appeals, and revision and enforcement conditions.In-depth interviews were held with key informants using pretested interview guides, supplemented with a review of the treatment guideline. Purposeful sampling was used in order to explore the perceptions of people with different backgrounds and perspectives. The analysis followed an editing organising style. Publicity: The selection decision of artemether-lumefantrine but not the rationale behind it was publicised through radio, television, and newspaper channels in the national language, Swahili. Relevance: The decision was grounded on evidences of clinical efficacy, safety, affordability, and formulation profile. Stakeholders were not adequately involved. There was neither an appeals mechanism to challenge the decision nor enforcement mechanisms to guarantee fairness of the decision outcomes. The priority-setting decision to use artemether-lumefantrine as the first-line antimalarial drug failed to satisfy the four conditions of the accountability for reasonableness framework. In our understanding, this is the first study to evaluate priority-setting decisions for new drugs in Tanzania against the accountability for reasonableness framework. In addition to the demand for enhanced stakeholder involvement, publicity, and transparency, the study also calls for the institution of formal appeals, revision, and regulatory mechanisms in the future change of malaria treatment policies.\u

    Change in basic motor abilities, quality of movement and everyday activities following intensive, goal-directed, activity-focused physiotherapy in a group setting for children with cerebral palsy

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    Background: The effects of intensive training for children with cerebral palsy (CP) remain uncertain. The aim of the study was to investigate the impact on motor function, quality of movements and everyday activities of three hours of goal-directed activity-focused physiotherapy in a group setting, five days a week for a period of three weeks. Methods: A repeated measures design was applied with three baseline and two follow up assessments; immediately and three weeks after intervention. Twenty-two children with hemiplegia (n = 7), diplegia (n = 11), quadriplegia (n = 2) and ataxia (n = 2) participated, age ranging 3-9 y. All levels of Gross Motor Function Classification System (GMFCS) and Manual Ability Classification System (MACS) were represented. Parents and professionals participated in goal setting and training. ANOVA was used to analyse change over repeated measures. Results: A main effect of time was shown in the primary outcome measure; Gross Motor Function Measure-66 (GMFM- 66), mean change being 4.5 (p < 0.01) from last baseline to last follow up assessment. An interaction between time and GMFCS-levels was found, implying that children classified to GMFCS-levels I-II improved more than children classified to levels III-V. There were no main or interaction effects of age or anti-spastic medication. Change scores in the Pediatric Evaluation of Disability Inventory (PEDI) ranged 2.0-6.7, p < 0.01 in the Self-care domain of the Functional Skills dimension, and the Self-care and Mobility domains of the Caregiver Assistance dimension. The children's individual goals were on average attained, Mean Goal Attainment Scaling (GAS) T-score being 51.3. Non-significant improved scores on the Gross Motor Performance Measure (GMPM) and the Quality of Upper Extremities Skills Test (QUEST) were demonstrated. Significant improvement in GMPM scores were found in improved items of the GMFM, not in items that maintained the same score. Conclusions: Basic motor abilities and self-care improved in young children with CP after goal-directed activityfocused physiotherapy with involvement of their local environment, and their need for caregiver assistance in self-care and mobility decreased. The individualized training within a group context during a limited period of time was feasible and well-tolerated. The coherence between acquisition of basic motor abilities and quality of movement should be further examined

    An equal right to inherit? Women's land rights, customary law and constitutional reform in Tanzania

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    This article explores contemporary contestations surrounding women’s inheritance of land in Africa. Legal activism has gained momentum, both in agendas for law reform and in test case litigation, which reached United Nations Committee on the Elimination of Discrimination against Women in ES and SC v. United Republic of Tanzania. Comparing the approach of Tanzania to that of its neighbours, Uganda, Kenya and Rwanda, this article explores patterns of resistance and omission towards enshrining an equal right to inherit in land and succession laws. It identifies two main reasons: neoliberal drivers for land law reform of the 1990s and sociopolitical sensitivity surrounding inheritance of land. It argues that a progressive approach to constitutional and law reform on women’s land rights requires understanding of the realities of claims to family land based on kinship relations. It calls for a holistic approach to land, marriage and inheritance law reform underpinned with constitutional rights to equality and progressive interpretations of living customary law

    Evaluating Sex and Age Differences in ADI-R and ADOS Scores in a Large European Multi-site Sample of Individuals with Autism Spectrum Disorder

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    Research on sex-related differences in Autism Spectrum Disorder (ASD) has been impeded by small samples. We pooled 28 datasets from 18 sites across nine European countries to examine sex differences in the ASD phenotype on the ADI-R (376 females, 1763 males) and ADOS (233 females, 1187 males). On the ADI-R, early childhood restricted and repetitive behaviours were lower in females than males, alongside comparable levels of social interaction and communication difficulties in females and males. Current ADI-R and ADOS scores showed no sex differences for ASD severity. There were lower socio-communicative symptoms in older compared to younger individuals. This large European ASD sample adds to the literature on sex and age variations of ASD symptomatology
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