Pattern of dyslipidemia in hypothyroid patients: A cross sectional study

Background: An association between thyroid dysfunction and dyslipidemia prevails. Levels of total cholesterol, low density lipoprotein cholesterol, triglycerides tend to increase as thyroid function declines.Objective: To find out the pattern of dyslipidemia in hypothyroid patients. Methods: Sixty cases were selected as a sample of convenience in this cross sectional study from in-patienl depa1tment of Medicine and Endocrinology, BSMMU. Meticulous history taking and thorough clinical examinations were done. Report of lipid profile and thyroid function tests were recorded from patients file. All the information's were recorded in a pre-designed sttuctured questionnaire. Collected data were classi­fied, edited, coded and entered into the computer for statistical analysis by using SPSS. Results: Among the 60 cases, 43 (72%) were female; 17(28%) were male. Age range was 24-59 years with a mean age of 38.80 (± I 0.35) years. Majority 38(65%) were housewife, followed by service holder 11(18.33%), 08(13.3%) were business men and 02(3.3%) had other occupations. Majority 42(70%) patients were taking thyroxin. Mean Total cholesterol (TC), LDL cholesterol, Triglycer­ide (TG) and HDL were 222.20(±42.25); 138.63(±31.51); 243.36(±83.13) and 37.30(±5.12) respectably. Conclusion: All hypothyroid subjects had dyslipidemia. The present study indicated that hypothyroidism was associated with an abnormal lipid profile, especially with respect to the levels of total cholesterol and triglyceride

Pattern of dyslipidemia in hypothyroid patients: A cross sectional study

Background: An association between thyroid dysfunction and dyslipidemia prevails. Levels of total cholesterol, low density lipoprotein cholesterol, triglycerides tend to increase as thyroid function declines. Objective: To find out the pattern of dyslipidemia in hypothyroid patients. Methods: Sixty cases were selected as a sample of convenience in this cross sectional study from in-patienl depa1tment of Medicine and Endocrinology, BSMMU. Meticulous history taking and thorough clinical examinations were done. Report of lipid profile and thyroid function tests were recorded from patients file. All the information's were recorded in a pre-designed sttuctured questionnaire. Collected data were classi­fied, edited, coded and entered into the computer for statistical analysis by using SPSS. Results: Among the 60 cases, 43 (72%) were female; 17(28%) were male. Age range was 24-59 years with a mean age of 38.80 (± I 0.35) years. Majority 38(65%) were housewife, followed by service holder 11(18.33%), 08(13.3%) were business men and 02(3.3%) had other occupations. Majority 42(70%) patients were taking thyroxin. Mean Total cholesterol (TC), LDL cholesterol, Triglycer­ide (TG) and HDL were 222.20(±42.25); 138.63(±31.51); 243.36(±83.13) and 37.30(±5.12) respectably. Conclusion: All hypothyroid subjects had dyslipidemia. The present study indicated that hypothyroidism was associated with an abnormal lipid profile, especially with respect to the levels of total cholesterol and triglyceride

Green synthesis of Bryophyllum pinnatum aqueous leaf extract mediated bio-molecule capped dilute ferromagnetic α-MnO2 nanoparticles

Bio-molecule capped α-MnO2 nanoparticles have been successfully synthesized from the reduction of KMnO4 via a facile green synthesis route using an aqueous leaf extract of Bryophyllum pinnatum as a reducing and capping agent. The synthesized α-MnO2 nanoparticles were characterized by x-ray diffraction (XRD), Fourier transform - infrared (FT-IR), energy dispersive x-ray (EDX), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), thermogravimetric (TG) and differential scanning calorimetry (DSC) techniques. Experimental results clearly demonstrate the successful synthesis of bio-molecule capped crystalline tetragonal α-MnO2 nanoparticles with the size of 4-18 nm. The magnetic property of the product was evaluated using a vibrating sample magnetometer (VSM) and the result reveals that the presently synthesized bio-molecule capped α-MnO2 nanoparticles exhibit ferromagnetic property at room temperature. © 2020 The Author(s). Published by IOP Publishing Ltd

Breadwinners and Homemakers: Migration and Changing Conjugal Expectations in Rural Bangladesh

The literature on marriage norms and aspirations across societies largely sees the institution as static – a tool for the assertion of masculinities and subordination of women. The changing meanings of marriage and conjugality in the contemporary context of globalisation have received scant attention. Based on research in rural Bangladesh, this article questions the usefulness of notions of autonomy and dependence in understanding conjugal relations and expectations in a context of widespread migration for extended periods, especially to overseas destinations, where mutuality is crucial for social reproduction, though in clearly genderdemarcated domains

Disaster experiences, associated problems and lessons in southwestern coastal Bangladesh: exploring through participatory rural appraisal to enhance resilience

The southwestern coastal part of Bangladesh is highly vulnerable to different kinds of disasters due to the changing climatic conditions. With the lenses of rural communities here an approach to examine how were the different disasters experiences, what lesson they learnt and what are their present disaster associated problems and stakeholder’s networks they rely on to enhance their resilience. Qualitative data were collected through participatory rapid rural appraisal (100–150 persons), field observation, 12 focus group discussions (25–40 people/FGD), and key informant interviews (25 people) in four southwestern coastal districts and nine coastal villages of Bangladesh. Results showed that since long back to date drinking water crisis, poor roads, poverty, poor sanitation, and health problems are the main identified disaster-associated problems. After learning lessons from previous disaster experiences, the community people have improved and changed their practices mainly by storing emergency foods, house construction, and increasing disaster awareness. However, the coastal communities are combating with the problems that have both direct and indirect association with poor infrastructures. Therefore, the coastal communities urge and sketched for a better stakeholders’ supports and networks to minimize their problems and thus to enhance communities’ disaster resilience

Primaquine radical cure in patients with Plasmodium falciparum malaria in areas co-endemic for P falciparum and Plasmodium vivax (PRIMA): a multicentre, open-label, superiority randomised controlled trial

Background In areas co-endemic for Plasmodium vivax and Plasmodium falciparum there is an increased risk of P vivax parasitaemia following P falciparum malaria. Radical cure is currently only recommended for patients presenting with P vivax malaria. Expanding the indication for radical cure to patients presenting with P falciparum malaria could reduce their risk of subsequent P vivax parasitaemia. Methods We did a multicentre, open-label, superiority randomised controlled trial in five health clinics in Bangladesh, Indonesia, and Ethiopia. In Bangladesh and Indonesia, patients were excluded if they were younger than 1 year, whereas in Ethiopia patients were excluded if they were younger than 18 years. Patients with uncomplicated P falciparum monoinfection who had fever or a history of fever in the 48 h preceding clinic visit were eligible for enrolment and were required to have a glucose-6-dehydrogenase (G6PD) activity of 70% or greater. Patients received blood schizontocidal treatment (artemether–lumefantrine in Ethiopia and Bangladesh and dihydroartemisinin–piperaquine in Indonesia) and were randomly assigned (1:1) to receive either high-dose short-course oral primaquine (intervention arm; total dose 7 mg/kg over 7 days) or standard care (standard care arm; single dose oral primaquine of 0·25 mg/kg). Random assignment was done by an independent statistician in blocks of eight by use of sealed envelopes. All randomly assigned and eligible patients were included in the primary and safety analyses. The per-protocol analysis excluded those who did not complete treatment or had substantial protocol violations. The primary endpoint was the incidence risk of P vivax parasitaemia on day 63. This trial is registered at ClinicalTrials.gov, NCT03916003. Findings Between Aug 18, 2019, and March 14, 2022, a total of 500 patients were enrolled and randomly assigned, and 495 eligible patients were included in the intention-to-treat analysis (246 intervention and 249 control). The incidence risk of P vivax parasitaemia at day 63 was 11·0% (95% CI 7·5–15·9) in the standard care arm compared with 2·5% (1·0–5·9) in the intervention arm (hazard ratio 0·20, 95% CI 0·08–0·51; p=0·0009). The effect size differed with blood schizontocidal treatment and site. Routine symptom reporting on day 2 and day 7 were similar between groups. In the first 42 days, there were a total of four primaquine-related adverse events reported in the standard care arm and 26 in the intervention arm; 132 (92%) of all 143 adverse events were mild. There were two serious adverse events in the intervention arm, which were considered unrelated to the study drug. None of the patients developed severe anaemia (defined as haemoglobin <5 g/dL). Interpretation In patients with a G6PD activity of 70% or greater, high-dose short-course primaquine was safe and relatively well tolerated and reduced the risk of subsequent P vivax parasitaemia within 63 days by five fold. Universal radical cure therefore potentially offers substantial clinical, public health, and operational benefits, but these benefits will vary with endemic setting. Funding Australian Academy of Science Regional Collaborations Program, Bill & Melinda Gates Foundation, and National Health and Medical Research Council

Log-moment estimators of the Nakagami-lognormal distribution

[EN] In this paper, estimators of the Nakagami-lognormal (NL) distribution based on the method of log-moments have been derived and thoroughly analyzed. Unlike maximum likelihood (ML) estimators, the log-moment estimators of the NL distribution are obtained using straightforward equations with a unique solution. Also, their performance has been evaluated using the sample mean, confidence regions and normalized mean square error (NMSE). The NL distribution has been extensively used to model composite small-scale fading and shadowing in wireless communication channels. This distribution is of interest in scenarios where the small-scale fading and the shadowing processes cannot be easily separated such as the vehicular environment.This work has been funded in part by the Programa de Estancias de Movilidad de Profesores e Investigadores en Centros Extranjeros de Ensenanza Superior e Investigacion of the Ministerio de Educacion, Cultura y Deporte, Spain, PR2015-00151 and by the Ministerio de Economia, Industria y Competitividad of the Spanish Government under the national project TEC2017-86779-C2-2-R, through the Agencia Estatal de Investigacion (AEI) and the Fondo Europeo de Desarrollo Regional (FEDER).Reig, J.; Brennan, C.; Rodrigo Peñarrocha, VM.; Rubio Arjona, L. (2019). Log-moment estimators of the Nakagami-lognormal distribution. EURASIP Journal on Wireless Communications and Networking. 1-10. https://doi.org/10.1186/s13638-018-1328-6S110J. M. Ho, G. L. 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Mathiopoulos, in Adaptive M-QAM systems with diversity in correlated Nakagami-m fading and shadowing. IEEE Global Telecommunications Conference (GLOBECOM 2010) (IEEEMiami, 2010), pp. 1–5.Ö. Bulakci, A. B. Saleh, J. Hämäläinen, S. Redana, Performance analysis of relay site planning over composite fading/shadowing channels with cochannel interference. IEEE Trans. Veh. Technol.62(4), 1692–1706 (2013).W. Cheng, Y. Huang, On the performance of adaptive SC/MRC cooperative systems over composite fading channels. Chin. J. Electron.25(3), 533–540 (2016).M. G. Kibria, G. P. Villardi, W. Liao, K. Nguyen, K. Ishizu, F. Kojima, Outage analysis of offloading in heterogeneous networks: Composite fading channels. IEEE Trans. Veh. Technol.66(10), 8990–9004 (2017).K. Cho, J. Lee, C. G. Kang, Stochastic geometry-based coverage and rate analysis under Nakagami & log-normal composite fading channel for downlink cellular networks. IEEE Commun. Lett.21(6), 1437–1440 (2017).R. Singh, M. Rawat, Closed-form distribution and analysis of a combined Nakagami-lognormal shadowing and unshadowing fading channel. J Telecommun. Inf. Technol.4:, 81–87 (2016).J. Reig, L. Rubio, Estimation of the composite fast fading and shadowing distribution using the log-moments in wireless communications. IEEE Trans. Wireless. Commun.12(8), 3672–3681 (2013).S. Atapattu, C. Tellambura, H. Jiang, A mixture gamma distribution to model the SNR of wireless channels. IEEE Trans. Wireless Commun.10(12), 4193–4203 (2011).Q. Wang, H. Lin, P. Kam, Tight bounds and invertible average error probability expressions over composite fading channels. J. Commun. Netw.18(2), 182–189 (2016).J. M. Holtzmann, On using perturbation analysis to do sensitivity analysis: derivatives versus differences. IEEE Trans. Autom. Control. 37(2), 243–247 (1992).H. Suzuki, A statistical model for urban radio propagation. IEEE Trans. Commun.25(7), 673–680 (1977).M. D. 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Delineating ethnic and religious identities in research with British South Asians

The present essay presents a rationale for delineating ethnic and religious identities in empirical research into self-identification among British South Asians. It is argued that the delineation of these identities is important in order to (i) predict and explain the identificatory possibilities available to these individuals; (ii) explore the differential values attributed to these identities; (iii) the level of psychological 'connectedness' between the identities; and (iv) the inter-relations between these identities, particularly in relation to psychological coherence. It is argued that a systematic delineation of these identities may have favourable theoretical, empirical and practical outcomes

Long-distance attachments and implications for tourism development: the case of the Western Ukrainian diaspora

This study analyzes the perspectives of roots tourism through the experiences of Western Ukrainian diaspora members. Their sense of attachment to the ancestral homeland and their visits to the places of origin are investigated, together with the views by tour operators specialized in roots tourism and public authorities dealing with tourism in the region, evaluating the actual or potential impact in terms of tourism development opportunities. The peculiar history of this territory makes it a distinct research target, with dynamics that are different from the rest of the country. The desire to turn Western Ukraine into a solid tourist destination and the aim of stimulating economic development in a region that is still struggling to re-emerge from its marginality are widespread and form a fertile basis for the growth of diaspora tourism as a solid asset. Lights and shadows emerge from the diaspora tourists’ experiences and perceptions. Specialized tour operators clearly see the enhancement of this form of tourism as an important business opportunity, while public authorities are not currently focusing on this segment, preferring general tourism promotion