154 research outputs found
Simulation of the spreading of a gas-propelled micro-droplet upon impact on a dry surface using a lattice-Boltzmann approach
Spray cooling is one of the most promising methods of cooling high heat flux electronics. Depending on the type of the nozzle, spray cooling can be categorized as single phase or two phase. In the latter, which is known to be more effective, a secondary gas is used to further pressurize the liquid and form smaller droplets at higher velocities. The gas is also assumed to assist the spreading phase by imposing normal and tangential forces on the droplet free surface which adds to the complicated hydrodynamics of the droplet impact. Moreover, the order of magnitude of droplet size in spray cooling is 10ÂŻâ¶m thereby introducing a low Weber and Reynolds numbers impact regime which heretofore has not been well understood. A 3D lattice Boltzmann method was implemented to simulate the impact of a single micro-droplet on a dry surface in both ambient air and under a stagnation gas flow. Two cases were closely compared and correlations were proposed for the instantaneous spreading diameter. Contrary to recent findings at higher impact We and Re, it was found that stagnation flow only significantly affects the spreading phase for Ca*â©Ÿ0.35 but has little influence on the receding physics
Validated Thermal Air Management Simulations of Data Centers Using Remote Graphics Processing Units
Simulation tools for thermal management of data centers help to improve layout of new builds or analyse thermal problems in existing data centers. The development of LBM on remote GPUs as an approach for such simulations is discussed making use of VirtualGL and prioritised multi-threaded implementations of an existing LBM code. The simulation is configured to model an existing and highly monitored test data center. Steady-state root mean square averages of measured and simulated temperatures are compared showing good agreement. The full capability of this simulation approach is demonstrated when comparing rack temperatures against a time varying workload, which employs time-dependent boundary conditions
Three computational methods for analysing thermal airflow distributions in the cooling of data centers
This paper develops computational models to study thermal airflow distribution when cooling a data center. The thermal airflow distribution study employs three computational approaches, namely finite element, finite volume and lattice Boltzmann methods, which are respectively implemented via commercial Multiphysics software, opensource CFD code and home grown GPU based code. The results focus on comparison of the three methods, all of which include models for turbulence, when applied to 2 rows of racks with cool air supplied by a plenum. Advantages and disadvantages of the three computational methods are addressed in terms of application to thermal management of data centers
A method to evaluate equitable accessibility: combining ethical theories and accessibility-based approaches
In this paper, we present the case that traditional transport appraisal methods do not sufficiently capture the social dimensions of mobility and accessibility. However, understanding this is highly relevant for policymakers to understand the impacts of their transport decisions. These dimensions include the distribution of mobility and accessibility levels over particular areas or for specific population groups, as well as how this may affect various social outcomes, including their levels of participation, social inclusion and community cohesion. In response, we propose a method to assess the socially relevant accessibility impacts (SRAIs) of policies in some of these key dimensions. The method combines the use of underlying ethics principles, more specifically the theories of egalitarianism and sufficientarianism, in combination with accessibility-based analysis and the Lorenz curve and Gini index. We then demonstrate the method in a case study example. Our suggestion is that policymakers can use these ethical perspectives to determine the equity of their policies decisions and to set minimum standards for local transport delivery. This will help them to become more confident in the development and adoption of new decision frameworks that promote accessibility over mobility and which also disaggregate the costs and benefits of transport policies over particular areas or for specific under-served population groups
Matrix Metalloproteinase-1 and -9 in Human Placenta during Spontaneous Vaginal Delivery and Caesarean Sectioning in Preterm Pregnancy
Preterm birth is a major public health problem in terms of loss of life, long-term and short term disabilities worldwide. The process of parturition (both term and preterm) involves intensive remodelling of the extracellular matrix (ECM) in the placenta and fetal membranes by matrix metalloproteinases (MMPs). Our previous studies show reduced docosahexaenoic acid (DHA) in women delivering preterm. Further omega 3 fatty acids are reported to regulate MMP levels. This study was undertaken to examine the placental levels of MMPs and their association with placental DHA levels in women delivering preterm. The levels of MMP-1 and MMP-9 in 74 women delivering preterm (52 by spontaneous vaginal delivery and 22 by caesarean sectioning) and 75 women delivering at term (59 by spontaneous vaginal delivery and 16 by caesarean sectioning) were determined by enzyme-linked immunosorbent assay (ELISA) and their association with placental DHA was studied. Placental MMP-1 levels were higher (p<0.05) in women delivering preterm (both by spontaneous vaginal delivery and caesarean sectioning) as compared to those delivering at term. In contrast, placental MMP-9 levels in preterm pregnancies was higher (p<0.05) in women with spontaneous vaginal delivery while lower (p<0.05) in women delivering by caesarean sectioning. Low placental DHA was associated with higher placental MMP-9 levels. Our study suggests a differential effect of mode of delivery on the levels of MMPs from placenta. Further this study suggests a negative association of DHA and the levels of MMP-9 in human placenta although the mechanisms need further study
Mapping species richness of plant families in European vegetation
Aims: Biodiversity is traditionally studied mostly at the species level, but biogeographical and macroecological studies at higher taxonomic levels can provide valuable insights into the evolutionary processes at large spatial scales. Our aim was to assess the representation of vascular plant families within different vegetation formations across Europe. Location: Europe. Methods: We used a data set of 816,005 vegetation plots from the European Vegetation Archive (EVA). For each plot, we calculated the relative species richness of each plant family as the number of species belonging to that family divided by the total number of species. We mapped the relative species richness, averaged across all plots in 50 km Ă 50 km grid cells, for each family and broad habitat groups: forests, grasslands, scrub and wetlands. We also calculated the absolute species richness and the Shannon diversity index for each family. Results: We produced 522 maps of mean relative species richness for a total of 152 vascular plant families occurring in forests, grasslands, scrub and wetlands. We found distinct spatial patterns for many combinations of families and habitat groups. The resulting series of 522 maps is freely available, both as images and GIS layers. Conclusions: The distinct spatial patterns revealed in the maps suggest that the relative species richness of plant families at the community level reflects the evolutionary history of individual families. We believe that the maps and associated data can inspire further biogeographical and macroecological studies and strengthen the ongoing integration of phylogenetic, functional and taxonomic diversity concepts.MV, IA, JPC, ZL, IK, AJ and MC were funded by the Czech Science Foundation, programme EXPRO (project no. 19-28491X); JDi by the Czech Science Foundation (18-02773S); IB and JAC by the Basque Government (IT936-16); AÄ by the Slovenian Research Agency (ARRS, P1-0236); AK by the National Research Foundation of Ukraine (project no. 2020.01/0140); JĆ by the Slovak Research and Development Agency (APVV 16-0431); KV by the National Science Fund (Contract DCOST 01/7/19.10.2018)
Porphyromonas gingivalis Participates in Pathogenesis of Human Abdominal Aortic Aneurysm by Neutrophil Activation. Proof of Concept in Rats
International audienceBACKGROUND: Abdominal Aortic Aneurysms (AAAs) represent a particular form of atherothrombosis where neutrophil proteolytic activity plays a major role. We postulated that neutrophil recruitment and activation participating in AAA growth may originate in part from repeated episodes of periodontal bacteremia. METHODS AND FINDINGS: Our results show that neutrophil activation in human AAA was associated with Neutrophil Extracellular Trap (NET) formation in the IntraLuminal Thrombus, leading to the release of cell-free DNA. Human AAA samples were shown to contain bacterial DNA with high frequency (11/16), and in particular that of Porphyromonas gingivalis (Pg), the most prevalent pathogen involved in chronic periodontitis, a common form of periodontal disease. Both DNA reflecting the presence of NETs and antibodies to Pg were found to be increased in plasma of patients with AAA. Using a rat model of AAA, we demonstrated that repeated injection of Pg fostered aneurysm development, associated with pathological characteristics similar to those observed in humans, such as the persistence of a neutrophil-rich luminal thrombus, not observed in saline-injected rats in which a healing process was observed. CONCLUSIONS: Thus, the control of periodontal disease may represent a therapeutic target to limit human AAA progression
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