Mission oriented study of advanced nuclear system parameters, phase 6. Volume 2 - Technical report Final report

Mission, trajectory, and vehicle details resulting from advanced nuclear propulsion study for Mars and Venus mission

Mission oriented study of advanced nuclear system parameters, phase 6. Volume 1 - Summary technical report Final report

Summarized study tasks, analyses, and results of advanced nuclear propulsion parameters for Mars and Venus mission

The Hybrid Hanger: A lightweight, portable hang-on tree stand with high durability and ease of use.

The Hybrid Hanger is a fully carbon fiber-epoxy composite hang-on tree stand. This 12-pound tree stand design allows a hunter to carry the stand further without fatiguing, which is perfect for public land hunters. In order to support the weight of a person and the harshness of hunting environments, the Hybrid Hanger will need to be strong and weather resistant. It has been tested to 600 pounds and the carbon fiber is an improvement upon the current metal stands of today’s market. Other qualities of the Hybrid Hanger that improve upon current tree stands in the market include: noise reduction, corrosion 41 resistance, and the compact and sleek design. The Hybrid Hanger will also be foldable with backpack straps to easily carry on a hunter’s back as they walk to their hunting location.https://openriver.winona.edu/urc2019/1021/thumbnail.jp

Nano-scale superhydrophobicity: suppression of protein adsorption and promotion of flow-induced detachment

Wall adsorption is a common problem in microfluidic devices, particularly when proteins are used. Here we show how superhydrophobic surfaces can be used to reduce protein adsorption and to promote desorption. Hydrophobic surfaces, both smooth and having high surface roughness of varying length scales (to generate superhydrophobicity), were incubated in protein solution. The samples were then exposed to flow shear in a device designed to simulate a microfluidic environment. Results show that a similar amount of protein adsorbed onto smooth and nanometer-scale rough surfaces, although a greater amount was found to adsorb onto superhydrophobic surfaces with micrometer scale roughness. Exposure to flow shear removed a considerably larger proportion of adsorbed protein from the superhydrophobic surfaces than from the smooth ones, with almost all of the protein being removed from some nanoscale surfaces. This type of surface may therefore be useful in environments, such as microfluidics, where protein sticking is a problem and fluid flow is present. Possible mechanisms that explain the behaviour are discussed, including decreased contact between protein and surface and greater shear stress due to interfacial slip between the superhydrophobic surface and the liquid

Communication of pharmacogenetic research results to HIV-infected treated patients: standpoints of professionals and patients.

International audienceThe aim of pharmacogenetic studies is to adapt therapeutic strategies to individual genetic profiles, thus maximising their efficacy and minimising the likelihood of adverse side effects. Since the advent of personalised medicine, the issue of communicating research results to participants has become increasingly important. We addressed this question in the context of HIV infection, as patients and associations are particularly concerned by research and therapeutic advances. We explored the standpoints of both research professionals and participants involved in a pharmacogenetic study conducted in a cohort of HIV-infected patients. The setting of the research protocol was followed over a 2-year period. Participants' standpoints were collected through a questionnaire and interviews were conducted with research professionals. Of 125 participants, 76% wished to receive individual results and 71% wished to receive collective results; 39% did not know when results might be expected. Communication of global research results is a principle that is generally accepted by professionals. Concerning individual feedback, the professionals felt that it was necessary if it could be of direct benefit to the participant, but they expressed doubts for situations with no recognised benefit. Our results highlight the necessity to consider this issue in greater detail. We suggest the need to anticipate the debates concerning individual feedback, to differentiate between situations and the importance of further investigations on the opportunities and modalities of communication. Finally, our work emphasised the opposite pressures between the pursuit of scientific knowledge and the therapeutic orientation of clinical trials