7,244 research outputs found
Monte Carlo evaluation of FADE approach to anomalous kinetics
In this paper we propose a comparison between the CTRW (Monte Carlo) and
Fractional Derivative approaches to the modelling of anomalous diffusion
phenomena in the presence of an advection field. Galilei variant and invariant
schemes are revised.Comment: 13 pages, 6 figure
Some Insights in Superdiffusive Transport
In this paper we deal with high-order corrections for the Fractional
Derivative approach to anomalous diffusion, in super-diffusive regime, which
become relevand whenever one attempts to describe the behavior of particles
close to normal diffusion.Comment: 14 pages, 7 figure
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State-Level and County-Level Estimates of Health Care Costs Associated with Food Insecurity.
IntroductionFood insecurity, or uncertain access to food because of limited financial resources, is associated with higher health care expenditures. However, both food insecurity prevalence and health care spending vary widely in the United States. To inform public policy, we estimated state-level and county-level health care expenditures associated with food insecurity.MethodsWe used linked 2011-2013 National Health Interview Survey/Medical Expenditure Panel Survey data (NHIS/MEPS) data to estimate average health care costs associated with food insecurity, Map the Meal Gap data to estimate state-level and county-level food insecurity prevalence (current though 2016), and Dartmouth Atlas of Health Care data to account for local variation in health care prices and intensity of use. We used targeted maximum likelihood estimation to estimate health care costs associated with food insecurity, separately for adults and children, adjusting for sociodemographic characteristics.ResultsAmong NHIS/MEPS participants, 10,054 adults and 3,871 children met inclusion criteria. Model estimates indicated that food insecure adults had annual health care expenditures that were 1,073-2,595, P < .001) higher than food secure adults. For children, estimates were 80 higher, but this finding was not significant (95% CI, -329, P = .53). The median annual health care cost associated with food insecurity was 239,675,000; 75th percentile, 4,433,000 (25th percentile, 11,267,000). Cost variability was related primarily to food insecurity prevalence.ConclusionsHealth care expenditures associated with food insecurity vary substantially across states and counties. Food insecurity policies may be important mechanisms to contain health care expenditures
A survey thesis of the personal reading preferences of children in the intermediate grades
Thesis (Ed.M.)--Boston Universit
Extracting the Single-Particle Gap in Carbon Nanotubes with Lattice Quantum Monte Carlo
We show how lattice Quantum Monte Carlo simulations can be used to calculate
electronic properties of carbon nanotubes in the presence of strong
electron-electron correlations. We employ the path integral formalism and use
methods developed within the lattice QCD community for our numerical work and
compare our results to empirical data of the Anti-Ferromagnetic Mott Insulating
gap in large diameter tubes.Comment: 8 pages, 5 figures, Lat2017 proceedin
Mitochondria as a Potential Antifungal Target for Isocyanide Compounds
The discovery of antibiotics and antifungals greatly impacted medicine and human health, allowing the effective treatment of infections that were previously deadly. However, due to routine and sometimes excessive usage of these compounds, the development of antimicrobial resistance has created a need for new antibiotic and antifungal compounds. Isocyanide compounds have been shown to have antibacterial, antifungal, and anti-cancer properties, but very little is known about their biochemical effects. Our research aims to understand the mechanism of action of isocyanide compounds. We have conducted a genetic screen of a Saccharomyces gene-deletion (“knockout”) collection on media containing an easily synthesized model isocyanide compound, para-nitrophenyl isocyanide (p-NPIC). This allowed us to identify genes which, when deleted, render the mutant strains resistant or hypersensitive to the compound. Based on our genetic screen for hypersensitive mutants, we hypothesize that the isocyanides impact mitochondrial function, specifically altering the function of the Cu++-containing respiratory complex, Cytochrome C Oxidase (Complex IV). Our findings provide new information on the mechanism(s) of action of this class of antimicrobials and will help guide the development of new molecules based on lead-compounds such as p-NPIC
Vacuum-ultraviolet frequency-modulation spectroscopy
Frequency-modulation (FM) spectroscopy has been extended to the
vacuum-ultraviolet (VUV) range of the electromagnetic spectrum. Coherent VUV
laser radiation is produced by resonance-enhanced sum-frequency mixing
() in Kr and Xe using two
near-Fourier-transform-limited laser pulses of frequencies
and . Sidebands generated in the output of the second laser ()
using an electro-optical modulator operating at the frequency
are directly transfered to the VUV and used to record FM
spectra. Demodulation is demonstrated both at and
. The main advantages of the method are that its
sensitivity is not reduced by pulse-to-pulse fluctuations of the VUV laser
intensity, compared to VUV absorption spectroscopy is its background-free
nature, the fact that its implementation using table-top laser equipment is
straightforward and that it can be used to record VUV absorption spectra of
cold samples in skimmed supersonic beams simultaneously with
laser-induced-fluorescence and photoionization spectra. To illustrate these
advantages we present VUV FM spectra of Ar, Kr, and N in selected regions
between 105000cm and 122000cm.Comment: 23 pages, 10 figure
Unemployment Insurance, Health-Related Social Needs, Health Care Access, and Mental Health During the COVID-19 Pandemic
More than 30 million jobs have been lost during the coronavirus disease 2019 (COVID-19) pandemic.1 Unemployment insurance (UI) was temporarily expanded by the Coronavirus Aid, Relief, and Economic Security (CARES) Act,2 but further reform is under debate. Key CARES Act provisions were adding $600 weekly federal payments to state payments (Federal Pandemic Unemployment Compensation), longer benefit duration (Pandemic Emergency Unemployment Compensation), and broadened eligibility for minimum-wage, self-employed, contract, and gig workers (Pandemic Unemployment Assistance)
Molecular Dynamics Simulation of Dipalmitoylphosphatidylserine Bilayer with Na+ Counterions
AbstractWe performed a molecular dynamics simulation of dipalmitoylphosphatidylserine (DPPS) bilayer with Na+ counterions. We found that hydrogen bonding between the NH3+ group and the phosphate group leads to a reduction in the area per headgroup when compared to the area in dipalmitoylphosphatidylcholine bilayer. The Na+ ions bind to the oxygen in the carboxyl group of serine, thus giving rise to a dipolar bilayer similar to dipalmitoylphosphatidylethanolamine bilayer. The results of the simulation show that counterions play a crucial role in determining the structural and electrostatic properties of DPPS bilayer
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