The dynamics of z~1 clusters of galaxies from the GCLASS survey

We constrain the internal dynamics of a stack of 10 clusters from the GCLASS survey at 0.87<z<1.34. We determine the stack cluster mass profile M(r) using the MAMPOSSt algorithm of Mamon et al., the velocity anisotropy profile beta(r) from the inversion of the Jeans equation, and the pseudo-phase-space density profiles Q(r) and Qr(r), obtained from the ratio between the mass density profile and the third power of the (total and, respectively, radial) velocity dispersion profiles of cluster galaxies. Several M(r) models are statistically acceptable for the stack cluster (Burkert, Einasto, Hernquist, NFW). The total mass distribution has a concentration c=r200/r-2=4.0-0.6+1.0, in agreement with theoretical expectations, and is less concentrated than the cluster stellar-mass distribution. The stack cluster beta(r) is similar for passive and star-forming galaxies and indicates isotropic galaxy orbits near the cluster center and increasingly radially elongated with increasing cluster-centric distance. Q(r) and Qr(r) are almost power-law relations with slopes similar to those predicted from numerical simulations of dark matter halos. Combined with results obtained for lower-z clusters we determine the dynamical evolution of galaxy clusters, and compare it with theoretical predictions. We discuss possible physical mechanisms responsible for the differential evolution of total and stellar mass concentrations, and of passive and star-forming galaxy orbits [abridged].Comment: 12 pages, 7 figures. Version accepted for publication in A&A after minor modification

A skewer survey of the Galactic halo from deep CFHT and INT images

We study the density profile and shape of the Galactic halo using deep multicolour images from the MENeaCS and CCCP projects, over 33 fields selected to avoid overlap with the Galactic plane. Using multicolour selection and PSF homogenization techniques we obtain catalogues of F stars (near-main sequence turnoff stars) out to Galactocentric distances up to 60kpc. Grouping nearby lines of sight, we construct the stellar density profiles through the halo in eight different directions by means of photometric parallaxes. Smooth halo models are then fitted to these profiles. We find clear evidence for a steepening of the density profile power law index around R=20 kpc, from -2.50 +- 0.04 to -4.85 +- 0.04, and for a flattening of the halo towards the poles with best-fit axis ratio 0.63 +- 0.02. Furthermore, we cannot rule out a mild triaxiality (w>=0.8). We recover the signatures of well-known substructure and streams that intersect our lines of sight. These results are consistent with those derived from wider but shallower surveys, and augur well for upcoming, wide-field surveys of comparable depth to our pencil beam surveys.Comment: 14 pages, 8 figures, 6 table

Finding halo streams with a pencil-beam survey: new wraps in the Sagittarius stream

We use data from two CFHT-MegaCam photometric pencil-beam surveys in the g' and the r' bands to measure distances to the Sagittarius, the Palomar 5 and the Orphan stream. We show that, using a cross-correlation algorithm to detect the turnoff point of the main sequence, it is possible to overcome the main limitation of a two-bands pencil-beam survey, namely the lack of adjacent control-fields that can be used to subtract the foreground and background stars to enhance the signal on the colour-magnitude diagrams (CMDs). We describe the cross-correlation algorithm and its implementation. We combine the resulting main sequence turnoff points with theoretical isochrones to derive photometric distances to the streams. Our results (31 detections on the Sagittarius stream and one each for the Palomar 5 and the Orphan streams) confirm the findings by previous studies, expand the distance trend for the Sagittarius faint southern branch and, for the first time, trace the Sagittarius faint branch of the northern-leading arm out to 56 kpc. In addition, they show evidence for new substructure: we argue that these detections trace the continuation of the Sagittarius northern-leading arm into the southern hemisphere, and find a nearby branch of the Sagittarius trailing wrap in the northern hemisphere.Comment: 16 pages, 15 figures, 2 table

Asymmetric nanofluidic grating detector for differential refractive index measurement and biosensing.

Measuring small changes in refractive index can provide both sensitive and contactless information on molecule concentration or process conditions for a wide range of applications. However, refractive index measurements are easily perturbed by non-specific background signals, such as temperature changes or non-specific binding. Here, we present an optofluidic device for measuring refractive index with direct background subtraction within a single measurement. The device is comprised of two interdigitated arrays of nanofluidic channels designed to form an optical grating. Optical path differences between the two sets of channels can be measured directly via an intensity ratio within the diffraction pattern that forms when the grating is illuminated by a collimated laser beam. Our results show that no calibration or biasing is required if the unit cell of the grating is designed with an appropriate built-in asymmetry. In proof-of-concept experiments we attained a noise level equivalent to ∼10(-5) refractive index units (30 Hz sampling rate, 4 min measurement interval). Furthermore, we show that the accumulation of biomolecules on the surface of the nanochannels can be measured in real-time. Because of its simplicity and robustness, we expect that this inherently differential measurement concept will find many applications in ultra-low volume analytical systems, biosensors, and portable devices

U-Pb zircon dating of the Gruf Complex: disclosing the late Variscan granulitic lower crust of Europe stranded in the Central Alps

Permian granulites associated with noritic intrusions and websterites are a common feature of the post-Variscan European crust. Such granulites are common in the Southern Alps (e.g. Ivrea Zone), but occur only in the Gruf Complex in the Central Alps. To understand the geotectonic significance of these granulites, in particular in the context of Alpine migmatisation, zircons from 15 high-grade samples have been U-Pb dated by SHRIMP II analysis. Oscillatory zoned zircons from charnockite sheets, interpreted as melts generated through granulite facies fluid-absent biotite melting at 920-940°C, yield ages of 282-260Ma. Some of these zircons contain inclusions of opx, unequivocally attributable to the granulite facies, thus confirming a Permian age for the charnockites and associated granulites. Two samples from an enclave-rich orthogneiss sheet yield Cambrian and Ordovician zircon cores. Two deformed leucogranites and six ortho- and augengneisses, which compose two-thirds of the Gruf Complex, give zircon ages of 290-260Ma. Most zircons have milky rims with ages of 34-29Ma. These rims date the Alpine amphibolite facies migmatisation, an interpretation confirmed by directly dating a leucosome pocket from upper amphibolite facies metapelites. The Gruf charnockites associated with metre-scale schlieren and boudins of opx-sapphirine-garnet-granulites, websterites and gabbronorites can thus be identified as part of the post-Variscan European lower crust. A geotectonic reconstruction reveals that this piece of lower crust stranded in the (European) North upon rifting of the Neotethys, such contrasting the widespread granulite units in the Southern Alps. Emplacement of the Gruf lower crust into its present-day position occurred during migmatisation and formation of the Bergell Pluton in the aftermath of the breakoff of the European sla

Low complexity scalable MIMO sphere detection through antenna detection reordering

This paper describes a novel low complexity scalable multiple-input multiple-output (MIMO) detector that does not require preprocessing and the optimal squared l2-norm computations to achieve good bit error (BER) performance. Unlike existing detectors such as Flexsphere that use preprocessing before MIMO detection to improve performance, the proposed detector instead performs multiple search passes, where each search pass detects the transmit stream with a different permuted detection order. In addition, to reduce the number of multipliers required in the design, we use l1-norm in place of the optimal squared l2-norm. To ameliorate the BER performance loss due to l1- norm, we propose squaring then scaling the l1-norm. By changing the number of parallel search passes and using norm scaling, we show that this design achieves comparable performance to Flexsphere with reduced resource requirement or achieves BER performance close to exhaustive search with increased resource requirement.National Science Foundatio

Prospects for high-z cluster detections with Planck, based on a follow-up of 28 candidates using MegaCam@CFHT

The Planck catalogue of SZ sources limits itself to a significance threshold of 4.5 to ensure a low contamination rate by false cluster candidates. This means that only the most massive clusters at redshift z>0.5, and in particular z>0.7, are expected to enter into the catalogue, with a large number of systems in that redshift regime being expected around and just below that threshold. In this paper, we follow-up a sample of SZ sources from the Planck SZ catalogues from 2013 and 2015. In the latter maps, we consider detections around and at lower significance than the threshold adopted by the Planck Collaboration. To keep the contamination rate low, our 28 candidates are chosen to have significant WISE detections, in combination with non-detections in SDSS/DSS, which effectively selects galaxy cluster candidates at redshifts $z\gtrsim0.5$. By taking r- and z-band imaging with MegaCam@CFHT, we bridge the 4000A rest-frame break over a significant redshift range, thus allowing accurate redshift estimates of red-sequence cluster galaxies up to z~0.8. After discussing the possibility that an overdensity of galaxies coincides -by chance- with a Planck SZ detection, we confirm that 16 of the candidates have likely optical counterparts to their SZ signals, 13 (6) of which have an estimated redshift z>0.5 (z>0.7). The richnesses of these systems are generally lower than expected given the halo masses estimated from the Planck maps. However, when we follow a simplistic model to correct for Eddington bias in the SZ halo mass proxy, the richnesses are consistent with a reference mass-richness relation established for clusters detected at higher significance. This illustrates the benefit of an optical follow-up, not only to obtain redshift estimates, but also to provide an independent mass proxy that is not based on the same data the clusters are detected with, and thus not subject to Eddington bias.Comment: 13 pages, 7 figures. Accepted for publication in A&

Full counting statistics in a disordered free fermion system

The Full Counting Statistics (FCS) is studied for a one-dimensional system of non-interacting fermions with and without disorder. For two unbiased $L$ site lattices connected at time $t=0$, the charge variance increases as the natural logarithm of $t$, following the universal expression $\approx \frac{1}{\pi^2}\log{t}$. Since the static charge variance for a length $l$ region is given by $\approx \frac{1}{\pi^2}\log{l}$, this result reflects the underlying relativistic or conformal invariance and dynamical exponent $z=1$ of the disorder-free lattice. With disorder and strongly localized fermions, we have compared our results to a model with a dynamical exponent $z \ne 1$, and also a model for entanglement entropy based upon dynamical scaling at the Infinite Disorder Fixed Point (IDFP). The latter scaling, which predicts $\propto \log\log{t}$, appears to better describe the charge variance of disordered 1-d fermions. When a bias voltage is introduced, the behavior changes dramatically and the charge and variance become proportional to $(\log{t})^{1/\psi}$ and $\log{t}$, respectively. The exponent $\psi$ may be related to the critical exponent characterizing spatial/energy fluctuations at the IDFP.Comment: 10 pages, 14 figures; fixed typos; added references; added IDFP scaling based upon reference [1]; added finite bias section; fixed typo

Immunoinformatics: Predicting Peptide–MHC Binding

Immunoinformatics is a discipline that applies methods of computer science to study and model the immune system. A fundamental question addressed by immunoinformatics is how to understand the rules of antigen presentation by MHC molecules to T cells, a process that is central to adaptive immune responses to infections and cancer. In the modern era of personalized medicine, the ability to model and predict which antigens can be presented by MHC is key to manipulating the immune system and designing strategies for therapeutic intervention. Since the MHC is both polygenic and extremely polymorphic, each individual possesses a personalized set of MHC molecules with different peptide-binding specificities, and collectively they present a unique individualized peptide imprint of the ongoing protein metabolism. Mapping all MHC allotypes is an enormous undertaking that cannot be achieved without a strong bioinformatics component. Computational tools for the prediction of peptide?MHC binding have thus become essential in most pipelines for T cell epitope discovery and an inescapable component of vaccine and cancer research. Here, we describe the development of several such tools, from pioneering efforts to the current state-of-the-art methods, that have allowed for accurate predictions of peptide binding of all MHC molecules, even including those that have not yet been characterized experimentally.Fil: Nielsen, Morten. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; Argentina. Technical University of Denmark; DinamarcaFil: Andreatta, Massimo. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Investigaciones Biotecnológicas. Universidad Nacional de San Martín. Instituto de Investigaciones Biotecnológicas; ArgentinaFil: Peters, Bjoern. La Jolla Institute for Allergy and Immunology; Estados UnidosFil: Buus, Søren. Universidad de Copenhagen; Dinamarc