Review: The scope of clinical morbidity in sickle cell trait

Sickle cell trait (SCT), the heterozygous state of the sickle hemoglobin beta globin gene (HbAS) is carried by as many as 100 million individuals including up to 25% of the population in some regions of the World. Sickle cell trait is the best-characterized genetic polymorphism known to protect against falciparum malaria. Although SCT was initially considered as a benign condition, data are accumulating of serious morbidities in SCT individuals including increased incidence of hematuria, renal papillary necrosis, renal failure and malignancy, thromboembolic disorders, splenic infarction as a high altitude complication, and exercise-related rhabdomyolysis and sudden death. Despite these associations, the average life span of individuals with sickle cell trait is similar to that of the general population. Nonetheless, given the large number of people with sickle cell trait, it is important that physicians be aware of these associations. The aim of this article is to review publications reporting and discussing morbidities in SCT individuals

Measuring the effect of customer relationship management (CRM) components on the non financial performance of commercial banks: Egypt case

This paper presents customer relationship management (CRM) components as applied on the Egyptian Commercial Banks, examined from the bankers' point of view. Then, it intends to measure their effect on the level of customer satisfaction and loyalty from the customers’ point of view as examples of the non financial performance measures. The paper is quantitative in nature and consists of two different structured questionnaires using convenience/quota sampling. The first involved 180 employees in order to measure CRM applicability, and the second involved 270 customers to measure the level of customer satisfaction and loyalty and their effect on the Egyptian Commercial Banks' financial performance The findings show that the selected banks apply CRM components but the level of application differs from one bank to another. The results showed a significant positive relationship between CRM and customer satisfaction in the Egyptian Commercial Banks, when applying them together and not separately. In addition, there is a strong positive effect between customer satisfaction and loyalty which was reflected on the Commercial Banks' financial performance. The findings confirm the importance of studying and implementing CRM to achieve customer loyalty and improve the Egyptian Commercial Banks financial performance. Banks wishing to improve their relationships with customers need to focus on the CRM components to develop relevant and effective marketing strategies and tactics. The paper measures the CRM as a multidimensional construct as applied on the Egyptian Commercial Banks and relate it to the achievement of the ultimate goal of retaining customers to gaining a sustainable competitive advantage and achieve more profits

Fuzzy Soft Connected Sets in Fuzzy Soft Topological Spaces

In this paper we introduce some types of fuzzy soft separated sets and study some of thier preperties. Next, the notion of connectedness in fuzzy topological spaces due to Ming and Ming, Zheng etc., extended to fuzzy soft topological spaces. The relationship between these types of connectedness in fuzzy soft topological spaces is investigated with the help of number of counter examples

Soft Real Analysis

The Soft Real number is a parameterized collection real numbers. And by this relation, every properties of real numbers can be discussed in soft real numbers. In this paper, we introduce the operations on soft real numbers and define countable and uncountable soft real sets. Also, some concepts of real numbers such as( upper bound, lower bound, supermum and infimum) are introduced

Effects of Porosity, Rotation, Thermomagnetic, and Thickness Variation on Functionally Graded Tapered Annular Disks

This paper presents a study on porous functionally graded piezoelectric (FGP) annular disks. The paper discussed the magneto-electric-hygrothermal effects on rotating variable thickness porous FG annular disks. Material properties coefficients and magnetic permeability are changed in a power function of radius. The disk is subjected to various loading of a uniform magnetic field, hygrothermal effect, and variation of electric potentials and mechanical pressure on the disk. A semi-analytical technique is used to get the mathematical solution of the rotating annular disk. Numerical outcomes are provided to examine the porosity factor and grading index on the rotating of the disk by different four sets of boundary conditions. The results offered a comparison between the porous and non-porous annular disks with various boundary conditions. Finally, the mathematical solution is beneficial to the planning and manufacture of a rotating porous disk influenced by complex loading and conditions

Finite Element Modelling of Strengthened Simple Beams using FRP Techniques: A parametric Study

The main objective of this paper is to study analytically the strengthening of a simplereinforced concrete beams due to excessive uniform loads in flexure, shear and acombination of flexure and shear, using externally bonded FRP sheets technique. Acommercial finite element computer program ANSYS has been used to perform a structurallinear and non-linear analysis for several models using several schemes of FRP sheets. Aparametric study has been performed for a lot of strengthened beams. FE models studies amain parameter of different schemes of FRP sheets in flexure, shear and combinationflexure/shear. Comparing the results with a control beam model – simple reinforcedconcrete beam without strengthening – it is obvious that all strengthened beams have agreater ultimate capacity than the control beam and noticeable enhancement in memberductility. The increasing level differs as a result of the strengthening scheme. Thestrengthened beam in both flexure and shear gives a higher ultimate load capacity, delay thefailure and prevent debonding failure up to a level at which debonding occurs in bothlongitudinal and wrapped jackets CFRP sheets

Soft Fuzzy Syntopogenous Spaces

In this paper , we introduce the conceptes of semi-topogenous ( resp. topogenous )soft fuzzy order and the syntopogenous soft fuzzy structure and study many of their properties and show that there is a one-one corresponds between perfect topogenous soft fuzzy structures and soft fuzzy topological structure

Multiset proximity spaces

L

Pramipexole protective effect on rotenone induced neurotoxicity in mice

Introduction: 
Pramipexole is a new dopaminergic drug which has been approved for PD treatment. However, we tried to find a new capacity for this drug rather than symptomatic effect. 

Materials and Methods: 
A chronic rotenone model with daily oral dose of 30mg/kg was induced in mice. Pramipexole was tried in a new approach where the treatment began in the middle of rotenone course with oral dose 1mg/kg/day of pramipexole. 

Results: 
Further analysis of behavioral tests and immunohistochemistry revealed success of pramipexole in improving the rotenone intoxicated mice. 

Conclusion: 
These results showed possible beneficial effects of pramipexole against rotenone-induced neurotoxicity

New Solutions for System of Fractional Integro-Differential Equations and Abel’s Integral Equations by Chebyshev Spectral Method

Chebyshev spectral method based on operational matrix is applied to both systems of fractional integro-differential equations and Abel’s integral equations. Some test problems, for which the exact solution is known, are considered. Numerical results with comparisons are made to confirm the reliability of the method. Chebyshev spectral method may be considered as alternative and efficient technique for finding the approximation of system of fractional integro-differential equations and Abel’s integral equations