5,402 research outputs found
Role of magnesium in carbon partitioning and alleviating photooxidative damage
Magnesium (Mg) deficiency exerts a major influence on the partitioning of
drymatter and carbohydrates between shoots and roots. One of the very early
reactions of plants to Mg deficiency stress is themarked increase in the shootto-
root dry weight ratio, which is associated with a massive accumulation of
carbohydrates in source leaves, especially of sucrose and starch. These higher
concentrations of carbohydrates in Mg-deficient leaves together with the
accompanying increase in shoot-to-root dry weight ratio are indicative of
a severe impairment in phloem export of photoassimilates from source
leaves. Studies with common bean and sugar beet plants have shown that
Mg plays a fundamental role in phloem loading of sucrose. At a very early
stage of Mg deficiency, phloem export of sucrose is severely impaired, an
effect that occurs before any noticeable changes in shoot growth, Chl
concentration or photosynthetic activity. These findings suggest that accumulation
of carbohydrates in Mg-deficient leaves is caused directly by Mg
deficiency stress and not as a consequence of reduced sink activity. The role
of Mg in the phloem-loading process seems to be specific; resupplying Mg for
12 or 24 h to Mg-deficient plants resulted in a very rapid recovery of sucrose
export. It appears that the massive accumulation of carbohydrates and related
impairment in photosynthetic CO2 fixation in Mg-deficient leaves cause an
over-reduction in the photosynthetic electron transport chain that potentiates
the generation of highly reactive O2 species (ROS). Plants respond to Mg
deficiency stress by marked increases in antioxidative capacity of leaves,
especially under high light intensity, suggesting that ROS generation is
stimulated by Mg deficiency in chloroplasts. Accordingly, it has been found
that Mg-deficient plants are very susceptible to high light intensity. Exposure
of Mg-deficient plants to high light intensity rapidly induced leaf chlorosis
and necrosis, an outcome that was effectively delayed by partial shading of
the leaf blade, although the Mg concentrations in different parts of the leaf
blade were unaffected by shading. The results indicate that photooxidative
damage contributes to development of leaf chlorosis under Mg deficiency,
suggesting that plants under high-light conditions have a higher physiological
requirement for Mg. Maintenance of a high Mg nutritional status of plants is,
thus, essential in the avoidance of ROS generation, which occurs at the
expense of inhibited phloem export of sugars and impairment of CO2
fixation, particularly under high-light conditions
The glacial cycles and cosmic rays
The cause of the glacial cycles remains a mystery. The origin is widely
accepted to be astronomical since paleoclimatic archives contain strong
spectral components that match the frequencies of Earth's orbital modulation.
Milankovitch insolation theory contains similar frequencies and has become
established as the standard model of the glacial cycles. However, high
precision paleoclimatic data have revealed serious discrepancies with the
Milankovitch model that fundamentally challenge its validity and re-open the
question of what causes the glacial cycles. We propose here that the ice ages
are initially driven not by insolation cycles but by cosmic ray changes,
probably through their effect on clouds. This conclusion is based on a wide
range of evidence, including results presented here on speleothem growth in
caves in Austria and Oman, and on a record of cosmic ray flux over the past 220
kyr obtained from the 10Be composition of deep-ocean sediments
Nitric oxide-dependent vasodilation is compromised in isolated pulmonary arteries from COX knockout mice
Cyclooxygenase (COX) has two isoforms and is essential for prostanoid synthesis. COX-1 is constitutive whilst COX-2 is induced in inflammation. Two COX products, prostacyclin (PGI2) and thromboxane (TxA2), regulate vessel tone; PGI2 mediates vasodilation and platelet inhibition, and TxA2 opposes this. PGI2 therapies are used in pulmonary arterial hypertension (PAH). Endogenous TxA2/PGI2 has been linked to PAH in animal models, but the mechanism and isoform involved is debated. We hypothesized that pulmonary artery (PA) from COX-1–/– and COX-2–/– mice would have altered vasodilatory function compared with wild-type (WT; C57Bl6) mice. Vasomotor responses to contractile and relaxant agents were measured by myography. PA from all mice responded similarly to contraction by high potassium or the TxA2 mimetic, U46619. Relaxation to PGI2 receptor or PPARβ/ agonists was also similar in all PAs. However, COX-1–/– and, to a lesser extent, COX-2–/– PA had impaired vasodilation to acetylcholine (ACh), which stimulates endothelial nitric oxide (NO) release, and COX-1–/– PA also dilated less to sodium nitroprusside (SNP); an NO donor that works on smooth muscle (Fig 1). These data indicate an interaction between COX and NO sensing pathways in pulmonary vessels, and have implications for our understanding of PAH.Non peer reviewedFinal Accepted Versio
A logic boosting approach to inducing multiclass alternating decision trees
The alternating decision tree (ADTree) is a successful classification technique that combine decision trees with the predictive accuracy of boosting into a ser to interpretable classification rules. The original formulation of the tree induction algorithm restricted attention to binary classification problems. This paper empirically evaluates several methods for extending the algorithm to the multiclass case by splitting the problem into several two-class LogitBoost procedure to induce alternating decision trees directly. Experimental results confirm that this procedure is comparable with methods that are based on the original ADTree formulation in accuracy, while inducing much smaller trees
Characterizing temporary hydrological regimes at a European scale
Monthly duration curves have been constructed from climate data across Europe to help address the relative frequency of ecologically critical low flow stages in temporary rivers, when flow persists only in disconnected pools in the river bed. The hydrological model is 5 based on a partitioning of precipitation to estimate water available for evapotranspiration and plant growth and for residual runoff. The duration curve for monthly flows has then been analysed to give an estimate of bankfull flow based on recurrence interval. The corresponding frequency for pools is then based on the ratio of bank full discharge to pool flow, arguing from observed ratios of cross-sectional areas at flood 10 and low flows to estimate pool flow as 0.1% of bankfull flow, and so estimate the frequency of the pool conditions that constrain survival of river-dwelling arthropods and fish. The methodology has been applied across Europe at 15 km resolution, and can equally be applied under future climatic scenarios
Investigating eye movement acquisition and analysis technologies as a causal factor in differential prevalence of crossed and uncrossed fixation disparity during reading and dot scanning
Previous studies examining binocular coordination during reading have reported conflicting results in terms of the nature of disparity (e.g. Kliegl, Nuthmann, & Engbert (Journal of Experimental Psychology General 135:12-35, 2006); Liversedge, White, Findlay, & Rayner (Vision Research 46:2363-2374, 2006). One potential cause of this inconsistency is differences in acquisition devices and associated analysis technologies. We tested this by directly comparing binocular eye movement recordings made using SR Research EyeLink 1000 and the Fourward Technologies Inc. DPI binocular eye-tracking systems. Participants read sentences or scanned horizontal rows of dot strings; for each participant, half the data were recorded with the EyeLink, and the other half with the DPIs. The viewing conditions in both testing laboratories were set to be very similar. Monocular calibrations were used. The majority of fixations recorded using either system were aligned, although data from the EyeLink system showed greater disparity magnitudes. Critically, for unaligned fixations, the data from both systems showed a majority of uncrossed fixations. These results suggest that variability in previous reports of binocular fixation alignment is attributable to the specific viewing conditions associated with a particular experiment (variables such as luminance and viewing distance), rather than acquisition and analysis software and hardware.<br/
Soil organic matter: A review of research results
The role of soil OM is reviewed, with special reference to bean production. Soil physical properties, chemical properties, and biological effects are covered. The different interactions of soil management practices with soil OM, such as the implications of seasonal effects on decomposition, nutrient cycling in cereal- legume crops, minimization of losses of OM and nutrients, sources of OM, and management of crop residues, are also indicated. The benefits of composting are also reviewed; although few field trials on composting have been reported in Africa, the few research results obtained so far are summarized. Research needs for Africa, with particular reference to bean production, include (1) N and P balance studies in major cropping systems, (2) improved utilization of OM, (3) on-farm verification of management techniques with kraal or boma manure, (4) surveys of local sources of OM potentially for composting, (5) evaluation of different legumes and nonlegumes for green manuring and mulching, (6) determination of the effect of several OM sources on soil physicochemical properties, and (7) determination of the duration of surface-applied mulches. (CIAT
Weka: A machine learning workbench for data mining
The Weka workbench is an organized collection of state-of-the-art machine learning algorithms and data preprocessing tools. The basic way of interacting with these methods is by invoking them from the command line. However, convenient interactive graphical user interfaces are provided for data exploration, for setting up large-scale experiments on distributed computing platforms, and for designing configurations for streamed data processing. These interfaces constitute an advanced environment for experimental data mining. The system is written in Java and distributed under the terms of the GNU General Public License
The view from elsewhere: perspectives on ALife Modeling
Many artificial life researchers stress the interdisciplinary character of the field. Against such a backdrop, this report reviews and discusses artificial life, as it is depicted in, and as it interfaces with, adjacent disciplines (in particular, philosophy, biology, and linguistics), and in the light of a specific historical example of interdisciplinary research (namely cybernetics) with which artificial life shares many features. This report grew out of a workshop held at the Sixth European Conference on Artificial Life in Prague and features individual contributions from the workshop's eight speakers, plus a section designed to reflect the debates that took place during the workshop's discussion sessions. The major theme that emerged during these sessions was the identity and status of artificial life as a scientific endeavor
Exercise-induced asthma in a group of South African schoolchildren during physical education classes
Objectives. The study was conducted to ascertain whether physical education teachers, using a peak flow meter, could reliably screen for exercise-induced asthma (EIA) in children during free running.Design, setting and subjects. The study was conducted using a convenience sample of male pupils between the ages of 12 and 18 years. They were tested with a peak flow meter for peak expiratory flow rate (PEFR) and with a flow-volume curve for forced expiratory flow in 1 second (FEV1) before and 10 minutes after a self-paced free running test during physical education classes. Testing was undertaken by teachers using the peak flow meter and by a medical doctor using a flow-volume curve.Results. Using a 10% decrease in flow parameters (PEFR and FEV1), teachers detected EIA in 14.9% of pupils and the doctor detected EIA in 21.7% of pupils.Conclusion. We conclude that EIA is common and that teachers using a peak flow meter can detect EIA and thus screen for it; they do, however, underestimate the true magnitude of the problem
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