57 research outputs found
Monte Carlo Simulations of Powerful Neutron Interaction with Matter for the Goals of Disclosure of Hidden Explosives and Fissile Materials and for Treatment of Cancer Diseases versus their Experimental Verifications
Dense Plasma Focus: physics and applications (radiation material science, single-shot disclosure of hidden illegal objects, radiation biology and medicine, etc.)
The paper presents some outcomes obtained during the year of 2013 of the activity in the frame of the International Atomic Energy Agency Co-ordinated research project "Investigations of Materials under High Repetition and Intense Fusion-Relevant Pulses". The main results are related to the effects created at the interaction of powerful pulses of different types of radiation (soft and hard X-rays, hot plasma and fast ion streams, neutrons, etc. generated in Dense Plasma Focus (DPF) facilities) with various materials including those that are counted as perspective ones for their use in future thermonuclear reactors. Besides we discuss phenomena observed at the irradiation of biological test objects. We examine possible applications of nanosecond powerful pulses of neutrons to the aims of nuclear medicine and for disclosure of hidden illegal objects. Special attention is devoted to discussions of a possibility to create extremely large and enormously diminutive DPF devices and probabilities of their use in energetics, medicine and modern electronics
Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand.
OBJECTIVE: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV. DESIGN: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand. METHODS: One thousand and ninety-four children initiating a nonnucleoside reverse transcriptase inhibitor or boosted protease inhibitor based regimen aged 1-10 years were included. Super Imposition by Translation And Rotation (SITAR) models described growth from age 8 years using three parameters (average height, timing and shape of the growth spurt), dependent on age and height-for-age z-score (HAZ) (WHO references) at antiretroviral therapy (ART) initiation. Multivariate regression explored characteristics associated with these three parameters. RESULTS: At ART initiation, median age and HAZ was 6.4 [interquartile range (IQR): 2.8, 9.0] years and -1.2 (IQR: -2.3 to -0.2), respectively. Median follow-up was 9.1 (IQR: 6.9, 11.4) years. In girls, older age and lower HAZ at ART initiation were independently associated with a growth spurt which occurred 0.41 (95% confidence interval 0.20-0.62) years later in children starting ART age 6 to 10 years compared with 1 to 2 years and 1.50 (1.21-1.78) years later in those starting with HAZ less than -3 compared with HAZ at least -1. Later growth spurts in girls resulted in continued height growth into later adolescence. In boys starting ART with HAZ less than -1, growth spurts were later in children starting ART in the oldest age group, but for HAZ at least -1, there was no association with age. Girls and boys who initiated ART with HAZ at least -1 maintained a similar height to the WHO reference mean. CONCLUSION: Stunting at ART initiation was associated with later growth spurts in girls. Children with HAZ at least -1 at ART initiation grew in height at the level expected in HIV negative children of a comparable age
Malignancies among children and young people with HIV in Western and Eastern Europe and Thailand
Height and timing of growth spurt during puberty in young people living with vertically acquired HIV in Europe and Thailand
Objective: The aim of this study was to describe growth during puberty in young people with vertically acquired HIV.
Design: Pooled data from 12 paediatric HIV cohorts in Europe and Thailand.
Methods: One thousand and ninety-four children initiating a nonnucleoside reverse transcriptase inhibitor or boosted protease inhibitor based regimen aged 1-10 years were included. Super Imposition by Translation And Rotation (SITAR) models described growth from age 8 years using three parameters (average height, timing and shape of the growth spurt), dependent on age and height-for-age z-score (HAZ) (WHO references) at antiretroviral therapy (ART) initiation. Multivariate regression explored characteristics associated with these three parameters.
Results: At ART initiation, median age and HAZ was 6.4 [interquartile range (IQR): 2.8, 9.0] years and -1.2 (IQR: -2.3 to -0.2), respectively. Median follow-up was 9.1 (IQR: 6.9, 11.4) years. In girls, older age and lower HAZ at ART initiation were independently associated with a growth spurt which occurred 0.41 (95% confidence interval 0.20-0.62) years later in children starting ART age 6 to 10 years compared with 1 to 2 years and 1.50 (1.21-1.78) years later in those starting with HAZ less than -3 compared with HAZ at least -1. Later growth spurts in girls resulted in continued height growth into later adolescence. In boys starting ART with HAZ less than -1, growth spurts were later in children starting ART in the oldest age group, but for HAZ at least -1, there was no association with age. Girls and boys who initiated ART with HAZ at least -1 maintained a similar height to the WHO reference mean.
Conclusion: Stunting at ART initiation was associated with later growth spurts in girls. Children with HAZ at least -1 at ART initiation grew in height at the level expected in HIV negative children of a comparable age
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study
Background:
The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms.
Methods:
International, prospective observational study of 60â109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms.
Results:
âTypicalâ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (â€â18 years: 69, 48, 23; 85%), older adults (â„â70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each Pâ<â0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country.
Interpretation:
This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men
The importance of agritourism in rural development
The paper presents the role and importance of agritourism in rural development.
The concept and the essence of agritourism have been discussed, as well
as the state of its development in Poland. It was followed by presentation of the
preconditions for its development and its positive social and economic outcomes.
The risks and negative consequences of this form of tourism were analysed
Development issues of catenary surge protection system based on a varistor surge arresters
W artykule opisano zagadnienia zwiÄ
zane z ochronÄ
sieci trakcyjnej 3 kV DC przed przepiÄciami pochodzÄ
cymi od wyĆadowaĆ atmosferycznych i procesĂłw komutacyjnych. ZwiÄĆșle uwidoczniono problemy wynikajÄ
ce z istnienia tych przepiÄÄ, ich ĆșrĂłdeĆ i przedstawiono aktualny stan ochrony przed tymi przepiÄciami. OmĂłwiono koncepcjÄ ochrony przed przepiÄciami z wykorzystaniem warystorowych ogranicznikĂłw przepiÄÄ. Zaprezentowano wyniki badaĆ nowego systemu ochrony przed przepiÄciami.The article presents issue of determinating an optimal distance between varistors located on 3 kV DC catenary. Line attenuation as a function of distance has been determined during preliminary tests for the following measurement configurations: catenary network unloaded (open), catenary network charged by a value of resistance close to the value of wave impedance of the catenary network test section, catenary network charged by a low voltage varistor. The results allowed to estimate the optimal distance between the varistors and they were verified on the catenary network on Ć»migrĂłd Test Ring using a surge generator with an amplitude of about 15 kV and varistors designed to work in rail-way enviroment. The methodology and results of these studies were presented and analyzed in this paper
Development issues of catenary surge protection system based on a varistor surge arresters
W artykule opisano zagadnienia zwiÄ
zane z ochronÄ
sieci trakcyjnej 3 kV DC przed przepiÄciami pochodzÄ
cymi od wyĆadowaĆ atmosferycznych i procesĂłw komutacyjnych. ZwiÄĆșle uwidoczniono problemy wynikajÄ
ce z istnienia tych przepiÄÄ, ich ĆșrĂłdeĆ i przedstawiono aktualny stan ochrony przed tymi przepiÄciami. OmĂłwiono koncepcjÄ ochrony przed przepiÄciami z wykorzystaniem warystorowych ogranicznikĂłw przepiÄÄ. Zaprezentowano wyniki badaĆ nowego systemu ochrony przed przepiÄciami.The article presents issue of determinating an optimal distance between varistors located on 3 kV DC catenary. Line attenuation as a function of distance has been determined during preliminary tests for the following measurement configurations: catenary network unloaded (open), catenary network charged by a value of resistance close to the value of wave impedance of the catenary network test section, catenary network charged by a low voltage varistor. The results allowed to estimate the optimal distance between the varistors and they were verified on the catenary network on Ć»migrĂłd Test Ring using a surge generator with an amplitude of about 15 kV and varistors designed to work in rail-way enviroment. The methodology and results of these studies were presented and analyzed in this paper
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