The development of entrepreneurial potential among higher education students

This is the author accepted manuscript. The final version is available from the publisher via the DOI in this recordPurpose – The purpose of this paper is to increase the understanding of how entrepreneurial potential is developed among young people. Changes in individuals’ entrepreneurial intentions and the antecedents of intentions are investigated, as well as the impact of entrepreneurship education on the changes. Design/methodology/approach – Ajzen’s Theory of Planned Behavior (TPB) is applied. Longitudinal data from 197 HE students, in their first and third year of studies, is examined using path analysis. Findings – Overall the entrepreneurial intentions of HE students decreased over time. Intentions decreased particularly for those with high initial level of intentions, whereas the group with increasing intentions rose from low to neutral level of intentions. Changes in attitudes and perceived behavioral control have a significant positive impact. Versatile entrepreneurship courses have direct effect on changes in attitudes. Changes in attitudes have a dual role, as they influence change in both intentions and perceived behavioral control. The developed model explains 19 percent of the variance among women and 28 percent among men, suggesting gender differences in development of intentions. Research limitations/implications – Only one way of developing entrepreneurial potential in young people (i.e. education) is covered. The empirical sample is limited to one university. Practical implications – The results suggest versatile methods of entrepreneurship education are more effective in developing intentions than perhaps purely active modes. Gender differences should be considered when designing interventions to foster entrepreneurial potential. Originality/value – The research confirms with longitudinal individual-level data the applicability of TPB on entrepreneurial intentions and demonstrates the mediated impact of versatile entrepreneurship courses on changes in intentions.European Regional Development Fun

Characterization of globulin storage proteins of a low prolamin cereal species in relation to celiac disease

Brachypodium distachyon, a small annual grass with seed storage globulins as primary protein reserves was used in our study to analyse the toxic nature of non-prolamin seed storage proteins related to celiac disease. The main storage proteins of B. distachyon are the 7S globulin type proteins and the 11S, 12S seed storage globulins similar to oat and rice. Immunoblot analyses using serum samples from celiac disease patients were carried out followed by the identification of immune-responsive proteins using mass spectrometry. Serum samples from celiac patients on a gluten-free diet, from patients with Crohn's disease and healthy subjects, were used as controls. The identified proteins with intense serum-IgA reactivity belong to the 7S and 11-12S seed globulin family. Structure prediction and epitope predictions analyses confirmed the presence of celiac disease-related linear B cell epitope homologs and the presence of peptide regions with strong HLA-DQ8 and DQ2 binding capabilities. These results highlight that both MHC-II presentation and B cell response may be developed not only to prolamins but also to seed storage globulins. This is the first study of the non-prolamin type seed storage proteins of Brachypodium from the aspect of the celiac disease

Increasing prevalence and high incidence of celiac disease in elderly people: A population-based study

<p>Abstract</p> <p>Background</p> <p>Celiac disease may emerge at any age, but little is known of its appearance in elderly people. We evaluated the prevalence of the condition in individuals over 55 years of age, and determined the incidence of biopsy-proven celiac disease (CDb) and celiac disease including seropositive subjects for anti-tissue transglutaminase antibodies (CDb+s).</p> <p>Methods</p> <p>The study based on prevalence figures in 2815 randomly selected subjects who had undergone a clinical examination and serologic screening for celiac disease in 2002. A second screening in the same population was carried out in 2005, comprising now 2216 individuals. Positive tissue transglutaminase antibodies were confirmed with small bowel biopsy.</p> <p>Results</p> <p>Within three years the prevalence of CDb increased from 2.13 to 2.34%, and that of CDb+s from 2.45 to 2.70%. Five new cases were found among patients previously seronegative; two had minor abdominal symptoms and three were asymptomatic. The incidence of celiac disease in 2002–2005 was 0.23%, giving an annual incidence of 0.08% in this population.</p> <p>Conclusion</p> <p>The prevalence of celiac disease was high in elderly people, but the symptoms were subtle. Repeated screening detected five biopsy-proven cases in three years, indicating that the disorder may develop even in the elderly. Increased alertness to the disorder is therefore warranted.</p

Suhteissa muovautuvat johtajuudet yksityisen varhaiskasvatuksen johtajien moniäänisissä kertomuksissa

Tiivistelmä Artikkelissa tarkastellaan yksityisen varhaiskasvatuksen johtajuutta erilaisissa suhteissa muovautuvana ilmiönä. Tutkimuksessa on haastateltu erilaisissa johtajuuspositioissa olevia yksityisen varhaiskasvatuksen johtajia eri puolilta Suomea. Dialogisen analyysin avulla tunnistetaan haastatteluista johtajien puhuvan johtajuudesta suhteessa itseensä, elämänkulkuun, substanssiin, työhön, sidosryhmiin ja yhteiskuntaan. Johtajien puheissa erottuu kolme erilaista johtajuuskertomusta; elämäntapajohtajuus, tasapainoileva johtajuus ja kehittämisjohtajuus.Abstract The article examines the leadership of private early childhood education as a phenomenon that is shaped in different relations. The study draws on interviews with managers of private early childhood education in different leadership positions from across Finland. Dialogical analysis is used to identify narratives from interviews in which leaders talk about leadership in relation to themselves and their life course, substance, work, stakeholders, and society. Three different leadership narratives are discussed: leadership as a way of life, balancing leadership and developmental leadership