155 research outputs found
Control of post-transplant lymphoproliferative disorders and Kaposi's sarcoma by modulation of immunosuppression
Is children’s education associated with parental health? Evidence from the Philippines
This study examines the association between children’s education and parental health using data from the 2007 Philippine Study on Ageing. It employs a broad, more comprehensive, definition of health to capture the different health dimensions. By employing multiple indicators of health, this study is able to examine whether the influence of children's education is consistent across different health indicators. It also investigates whether parental behavior and receipt of support from children serve as pathways that mediate the relationship between children’s education and parental health. Findings show that older women whose children completed tertiary education have lower odds of reporting IADL or ADL difficulty compared with their counterparts whose children attained below tertiary education. These findings contribute to the growing evidence that education is not only an individual resource; rather it could be a household or family resource that could benefit other family members
Acute torsion of the gallbladder: a case report
This is an Open Access article distributed under the terms of the Creative Commons Attribution Licens
Global Leadership Initiative on Malnutrition (GLIM):Guidance on Validation of the Operational Criteria for the Diagnosis of Protein-Energy Malnutrition in Adults
Background The Global Leadership Initiative on Malnutrition (GLIM) created a consensus-based framework consisting of phenotypic and etiologic criteria to record the occurrence of malnutrition in adults. This is a minimum set of practicable indicators for use in characterizing a patient/client as malnourished, considering the global variations in screening and nutrition assessment, and to be used across different healthcare settings. As with other consensus-based frameworks for diagnosing disease states, these operational criteria require validation and reliability testing, as they are currently based solely on expert opinion. Methods Several forms of validation and reliability are reviewed in the context of GLIM, providing guidance on how to conduct retrospective and prospective studies for criterion and construct validity. Results There are some aspects of GLIM that require refinement; research using large databases can be employed to reach this goal. Machine learning is also introduced as a potential method to support identification of the best cut points and combinations of indicators for use with the different forms of malnutrition, which the GLIM criteria were created to denote. It is noted as well that validation and reliability testing need to occur in a variety of sectors and populations and with diverse persons using GLIM criteria. Conclusion The guidance presented supports the conduct and publication of quality validation and reliability studies for GLIM
Low availability of carnitine precursors as a possible reason for the diminished plasma carnitine concentrations in pregnant women
<p>Abstract</p> <p>Background</p> <p>It has been shown that plasma carnitine concentrations decrease markedly during gestation. A recent study performed with a low number of subjects suggested that this effect could be due to a low iron status which leads to an impairment of carnitine synthesis. The present study aimed to confirm this finding in a greater number of subjects. It was moreover intended to find out whether low carnitine concentrations during pregnancy could be due to a reduced availability of precursors of carnitine synthesis, namely trimethyllysine (TML) and Îł-butyrobetaine (BB).</p> <p>Methods</p> <p>Blood samples of 79 healthy pregnant women collected at delivery were used for this study.</p> <p>Results</p> <p>There was only a weak, non-significant (P > 0.05), correlation between plasma concentration of ferritin and those of free and total carnitine. There was no correlation between other parameters of iron status (plasma iron concentration, hemoglobin, MCV, MCH) and plasma concentration of free and total carnitine. There were, however, significant (P < 0.05) positive correlations between concentrations of TML and BB and those of free and total carnitine in plasma.</p> <p>Conclusions</p> <p>The results of this study suggest that an insufficient iron status is not the reason for low plasma carnitine concentrations observed in pregnant women. It is rather indicated that low plasma carnitine concentrations are caused by a low availability of precursors for carnitine synthesis during gestation.</p
Correction to: Perceived economic self-sufficiency: a country- and generation-comparative approach
After online first publication of the article, it was noticed that the family name of author Panos Tsakloglou was erroneously misspelt as Tsakoglou
Organising for innovation in regional innovation systems: from fragmented innovation ecosystems to the joint aim for competitiveness of offshore wind energy
Perceived economic self‑sufficiency: a countryand generation‑comparative approach
We thank Michael Camasso and Radha Jagannathan as well as Asimina Christoforou,
Gerbert Kraaykamp, Fay Makantasi, Tiziana Nazio, Kyriakos Pierrakakis, Jacqueline O’Reilly
and Jan van Deth for their contribution to the CUPESSE project (Seventh Framework Programme; Grant
Agreement No. 61325). CUPESSE received additional funding from the Mannheim Centre for European
Social Research (MZES) and the Field of Focus 4 “Self-Regulation and Regulation: Individuals and
Organisations” at Heidelberg University. We further acknowledge helpful comments on this article by
two anonymous reviewers. Julian Rossello provided valuable research assistance.Electronic supplementary material The online version of this article (https ://doi.org/10.1057/
s4130 4-018-0186-3) contains supplementary material, which is available to authorized users.Existing datasets provided by statistical agencies (e.g. Eurostat) show that the economic and financial crisis that unfolded in 2008 significantly impacted the lives and livelihoods of young people across Europe. Taking these official statistics as a starting point, the collaborative research project “Cultural Pathways to Economic Self-Sufficiency and Entrepreneurship in Europe” (CUPESSE) generated new survey data on the economic and social situation of young Europeans (18–35 years). The CUPESSE dataset allows for country-comparative assessments of young people’s perceptions about their socio-economic situation. Furthermore, the dataset includes a variety of indicators examining the socio-economic situation of both young adults and their parents. In this data article, we introduce the CUPESSE dataset to political and social scientists in an attempt to spark a debate on the measurements, patterns and mechanisms of intergenerational transmission of economic self-sufficiency as well as its political implications.CUPESSE project (Seventh Framework Programme; Grant Agreement No. 61325
The Impact of Social Support Networks on Maternal Employment: A Comparison of West German, East German and Migrant Mothers of Pre-School Children
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