126 research outputs found
WE-H-BRA-07: Mechanistic Modelling of the Relative Biological Effectiveness of Heavy Charged Particles
Proline-rich sequence recognition I: Marking GYF and WW domain assembly sites in early spliceosomal complexes.
First Measurement of the He3+He3-->He4+2p Cross Section down to the Lower Edge of the Solar Gamow Peak
We give the LUNA results on the cross section measurement of a key reaction
of the proton-proton chain strongly affecting the calculated neutrino
luminosity from the Sun: He3+He3-->He4+2p. Due to the cosmic ray suppression
provided by the Gran Sasso underground laboratory it has been possible to
measure the cross section down to the lower edge of the solar Gamow peak, i.e.
as low as 16.5 keV centre of mass energy. The data clearly show the cross
section increase due to the electron screening effect but they do not exhibit
any evidence for a narrow resonance suggested to explain the observed solar
neutrino flux.Comment: 5 pages, RevTeX, and 2 figures in PostScript Submitted for
publicatio
Low-energy cross section of the 7Be(p,g)8B solar fusion reaction from Coulomb dissociation of 8B
Final results from an exclusive measurement of the Coulomb breakup of 8B into
7Be+p at 254 A MeV are reported. Energy-differential Coulomb-breakup cross
sections are analyzed using a potential model of 8B and first-order
perturbation theory. The deduced astrophysical S_17 factors are in good
agreement with the most recent direct 7Be(p,gamma)8B measurements and follow
closely the energy dependence predicted by the cluster-model description of 8B
by Descouvemont. We extract a zero-energy S_17 factor of 20.6 +- 0.8 (stat) +-
1.2 (syst) eV b.Comment: 14 pages including 16 figures, LaTeX, accepted for publication in
Physical Review C. Minor changes in text and layou
Consistency checks of results from a Monte Carlo code intercomparison for emitted electron spectra and energy deposition around a single gold nanoparticle irradiated by X-rays
Organized by the European Radiation Dosimetry Group (EURADOS), a Monte Carlo code intercomparison exercise was conducted where participants simulated the emitted electron spectra and energy deposition around a single gold nanoparticle (GNP) irradiated by X-rays. In the exercise, the participants scored energy imparted in concentric spherical shells around a spherical volume filled with gold or water as well as the spectral distribution of electrons leaving the GNP. Initially, only the ratio of energy deposition with and without GNP was to be reported. During the evaluation of the exercise, however, the data for energy deposition in the presence and absence of the GNP were also requested. A GNP size of 50 nm and 100 nm diameter was considered as well as two different X-ray spectra (50 kVp and 100 kVp). This introduced a redundancy that can be used to cross-validate the internal consistency of the simulation results. In this work, evaluation of the reported results is presented in terms of integral quantities that can be benchmarked against values obtained from physical properties of the radiation spectra and materials involved. The impact of different interaction cross-section datasets and their implementation in the different Monte Carlo codes is also discussed
Polymorphisms in IL12A and cockroach allergy in children with asthma
<p>Abstract</p> <p>Background</p> <p>IL12A has been implicated in T-cell development and may thus influence the development of atopy and allergic diseases.</p> <p>Methods</p> <p>We tested for association between four linkage disequilibrium (LD)-tagging SNPs (rs2243123, rs2243151, rs668998, and rs17826053) in <it>IL12A </it>and asthma and allergy-related (serum total and allergen-specific IgE, and skin test reactivity [STR] to two common allergens) phenotypes in two samples: 417 Costa Rican children with asthma and their parents, and 470 families of 503 white children in the Childhood Asthma Management Program (CAMP). The analysis was conducted using the family-based association test (FBAT) statistic implemented in the PBAT program.</p> <p>Results</p> <p>Among Costa Rican children with asthma, homozygosity for the minor allele of each of two SNPs in <it>IL12A </it>(rs2243123 and rs2243151) was associated with increased risks of STR to American cockroach (P ≤ 0.03 for both SNPs), STR to German cockroach (P ≤ 0.01 for both SNPs), and having a positive IgE to German cockroach (P < 0.05 for both SNPs). Among children in CAMP, homozygosity for the minor allele of SNP rs2243151 in <it>IL12A </it>was inversely associated with STR to German cockroach (P = 0.03) and homozygosity for the minor allele of SNP rs17826053 in <it>IL12A </it>was associated with increased risks of STR to American cockroach (P = 0.01) and STR to German cockroach (P = 0.007). There was no significant association between any SNP in <it>IL12A </it>and asthma, STR to dust mite, or total IgE in Costa Rica or CAMP.</p> <p>Conclusion</p> <p>Our findings suggest that variants in <it>IL12A </it>influence cockroach allergy among children with asthma.</p
First direct measurement of the total cross section of 12C(alpha,gamma)16O
The total cross section of 12C(alpha,gamma)16O was measured for the first
time by a direct and ungated detection of the 16O recoils. This measurement in
inverse kinematics using the recoil mass separator ERNA in combination with a
windowless He gas target allowed to collect data with high precision in the
energy range E=1.9 to 4.9 MeV. The data represent new information for the
determination of the astrophysical S(E) factor.Comment: 5 pages, 3 figures, 1 table, accepted for publication Eur.Phys.J. A
(Online first available
Evidence for the Appearance of Atmospheric Tau Neutrinos in Super-Kamiokande
Super-Kamiokande atmospheric neutrino data were fit with an unbinned maximum
likelihood method to search for the appearance of tau leptons resulting from
the interactions of oscillation-generated tau neutrinos in the detector.
Relative to the expectation of unity, the tau normalization is found to be
1.42 \pm 0.35 \ (stat) {\}^{+0.14}_{-0.12}\ (syst) excluding the
no-tau-appearance hypothesis, for which the normalization would be zero, at the
3.8 level. We estimate that 180.1 \pm 44.3\ (stat)
{\}^{+17.8}_{-15.2}\ (syst) tau leptons were produced in the 22.5 kton
fiducial volume of the detector by tau neutrinos during the 2806 day running
period. In future analyses, this large sample of selected tau events will allow
the study of charged current tau neutrino interaction physics with oscillation
produced tau neutrinos.Comment: 7 pages, 4 figures. This is the version as published in Physical
Review Letters including the supplemental figure. A typographical error in
the description of figure 3 is also correcte
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