Устройство защиты оборудования автоматизации от сверхкоротких электромагнитных импульсов

Цель работы – разработка и совершенствование нового устройства защиты оборудования автоматизации от сверхкоротких импульсов путем проведения вычислительных и натурных экспериментов при различных параметрах устройства. В данной выпускной квалификационной работе был разработан прототип устройства защиты оборудования автоматизации от СКИ, проведено экспериментальное подтверждение результатов моделирования его электрических характеристик. Исследован способ уменьшения времени моделирования. Выявлена схема включения устройства, обладающая бо?льшим коэффициентом ослабления помехового импульса. Выявлена закономерность в моментах прихода импульсов на выходе устройства, которые не наблюдались ранее.The purpose of the work is the development and improvement of a new device for protecting automation equipment against ultrashort pulses by performing computational and full-scale experiments at various device parameters. In this final qualifying work, a prototype of the protection device for automation equipment from the SRS was developed, and experimental results of simulation of its electrical characteristics were verified. A method for reducing simulation time has been studied. A circuit for switching on the device is revealed, which has a large coefficient of attenuation of the interference pulse. A regularity is revealed in the moments of arrival of pulses at the output of the device, which were not observed earlier

Comprehensive analysis of the chromatin landscape in Drosophila melanogaster.

Chromatin is composed of DNA and a variety of modified histones and non-histone proteins, which have an impact on cell differentiation, gene regulation and other key cellular processes. Here we present a genome-wide chromatin landscape for Drosophila melanogaster based on eighteen histone modifications, summarized by nine prevalent combinatorial patterns. Integrative analysis with other data (non-histone chromatin proteins, DNase I hypersensitivity, GRO-Seq reads produced by engaged polymerase, short/long RNA products) reveals discrete characteristics of chromosomes, genes, regulatory elements and other functional domains. We find that active genes display distinct chromatin signatures that are correlated with disparate gene lengths, exon patterns, regulatory functions and genomic contexts. We also demonstrate a diversity of signatures among Polycomb targets that include a subset with paused polymerase. This systematic profiling and integrative analysis of chromatin signatures provides insights into how genomic elements are regulated, and will serve as a resource for future experimental investigations of genome structure and function

Fabrication of photonic components by nanoimprint technology within ePIXnet

The joined research activities on nanoimprint lithography (JRA-NIL) within a European Network of Excellence (ePIXnet) are described. The achievements are presented in three different exemplary applications

Технологии набора и отбора персонала в угледобывающей отрасли на примере шахты "Казахстанская"

Объект исследования: АО шахта "Казахстанская" угледобывающее предприятие. Предмет исследования: Процессы отбора и подбора персонала в угледобывающей отрасли. Цель работы: Разработать рекомендации по совершенствованию системы подбора, отбора и найма персонала в штат АО шахта "Казахстанская".Object of investigation: JSC mine "Kazakhstan" coal-mining enterprise. Subject matter: Selection and selection processes in the coal mining industry. Objective: To develop recommendations for improving the system of recruitment, selection and recruitment of staff in the staff of JSC "Kazakhstan" mine

New heuristics for minimum weight triangulation

In rendering it is sometimes desirable to compute minimum total light energy mesh. This requires finding the solution for minimum weight triangulation (MWT). We have introduced several new heuristics for MWT, based on original observations. All new algorithms are tested on a set of randomly generated examples. For each example we compute the optimum (for small data sets) using backtrack technique or a reference suboptimum using simulated annealing technique. We compare the new heuristic

“Jump Start and Gain” Model for Dosage Compensation in Drosophila Based on Direct Sequencing of Nascent Transcripts

Dosage compensation in Drosophila is mediated by the MSL complex, which increases male X-linked gene expression approximately two-fold. The MSL complex preferentially binds the bodies of active genes on the male X, depositing H4K16ac with a 3′ bias. Two models have been proposed for the influence of the MSL complex on transcription: one based on promoter recruitment of RNA polymerase II (Pol II), and a second featuring enhanced transcriptional elongation. Here we utilize nascent RNA-sequencing to document dosage compensation during transcriptional elongation. We also compare X and autosomes from published data on paused and elongating polymerase to assess the role of Pol II recruitment. Our results support a model for differentially regulated elongation, starting with release from 5′ pausing and increasing through X-linked gene bodies. Our results highlight facilitated transcriptional elongation as a key mechanism for coordinated regulation of a diverse set of genes